 Binding, Competitive
"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
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| MeSH Number(s) |
E05.196.080 G02.111.087.090 G02.111.570.120.309 G02.149.115.090
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 2 | 2 | | 1988 | 1 | 1 | 2 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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Padroni G, Parkinson JA, Fox KR, Burley GA. Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides. Nucleic Acids Res. 2018 01 09; 46(1):42-53.
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Madsen J, Gaiha GD, Palaniyar N, Dong T, Mitchell DA, Clark HW. Surfactant Protein D modulates HIV infection of both T-cells and dendritic cells. PLoS One. 2013; 8(3):e59047.
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Tolg C, Hamilton SR, Zalinska E, McCulloch L, Amin R, Akentieva N, Winnik F, Savani R, Bagli DJ, Luyt LG, Cowman MK, McCarthy JB, Turley EA. A RHAMM mimetic peptide blocks hyaluronan signaling and reduces inflammation and fibrogenesis in excisional skin wounds. Am J Pathol. 2012 Oct; 181(4):1250-70.
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Meehan TP, Tabeta K, Du X, Woodward LS, Firozi K, Beutler B, Justice MJ. Point mutations in the melanocortin-4 receptor cause variable obesity in mice. Mamm Genome. 2006 Dec; 17(12):1162-71.
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Hanson J, Reynaud D, Qiao N, Devel P, Moray AL, Renard JF, Kelley LP, Winum JY, Montero JL, Kinsella BT, Pirotte B, Pace-Asciak CR, Dogné JM. Synthesis and pharmacological evaluation of novel nitrobenzenic thromboxane modulators as antiplatelet agents acting on both the alpha and beta isoforms of the human thromboxane receptor. J Med Chem. 2006 Jun 15; 49(12):3701-9.
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Nadesalingam J, Dodds AW, Reid KB, Palaniyar N. Mannose-binding lectin recognizes peptidoglycan via the N-acetyl glucosamine moiety, and inhibits ligand-induced proinflammatory effect and promotes chemokine production by macrophages. J Immunol. 2005 Aug 01; 175(3):1785-94.
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Beites CL, Campbell KA, Trimble WS. The septin Sept5/CDCrel-1 competes with alpha-SNAP for binding to the SNARE complex. Biochem J. 2005 Jan 15; 385(Pt 2):347-53.
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Mulvihill DJ, Nichol Edamura K, Hagerman KA, Pearson CE, Wang YH. Effect of CAT or AGG interruptions and CpG methylation on nucleosome assembly upon trinucleotide repeats on spinocerebellar ataxia, type 1 and fragile X syndrome. J Biol Chem. 2005 Feb 11; 280(6):4498-503.
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Palaniyar N, Nadesalingam J, Clark H, Shih MJ, Dodds AW, Reid KB. Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin. J Biol Chem. 2004 Jul 30; 279(31):32728-36.
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Tsay MJ, Fatemi N, Narindrasorasak S, Forbes JR, Sarkar B. Identification of the "missing domain" of the rat copper-transporting ATPase, atp7b: insight into the structural and metal binding characteristics of its N-terminal copper-binding domain. Biochim Biophys Acta. 2004 Jan 20; 1688(1):78-85.
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