 Serotonin
"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
| Descriptor ID |
D012701
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| MeSH Number(s) |
D02.092.211.215.801.852 D03.438.473.914.814 D23.469.050.650
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| Concept/Terms |
Serotonin- Serotonin
- Hippophaine
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
- Enteramine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- 5-HT
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Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 2 | 2 | | 1989 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 1 | 2 | | 1994 | 0 | 2 | 2 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 1 | 2 | | 2002 | 0 | 3 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 2 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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Kim H, Kim YG, Choi W, Moon JH, Hwang I, Kim K, Yadav VK, Karsenty G, Jeong JS, Kim H. Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Sci Rep. 2018 12 05; 8(1):17642.
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Ellegood J, Yee Y, Kerr TM, Muller CL, Blakely RD, Henkelman RM, Veenstra-VanderWeele J, Lerch JP. Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging. Mol Autism. 2018; 9:24.
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Kim YG, Moon JH, Kim K, Kim H, Kim J, Jeong JS, Lee J, Kang S, Park JS, Kim H. ß-cell serotonin production is associated with female sex, old age, and diabetes-free condition. Biochem Biophys Res Commun. 2017 11 25; 493(3):1197-1203.
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Haynes RL, Frelinger AL, Giles EK, Goldstein RD, Tran H, Kozakewich HP, Haas EA, Gerrits AJ, Mena OJ, Trachtenberg FL, Paterson DS, Berry GT, Adeli K, Kinney HC, Michelson AD. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7695-7700.
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Sinopoli VM, Burton CL, Kronenberg S, Arnold PD. A review of the role of serotonin system genes in obsessive-compulsive disorder. Neurosci Biobehav Rev. 2017 Sep; 80:372-381.
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Livermore S, Zhou Y, Pan J, Yeger H, Nurse CA, Cutz E. Pulmonary neuroepithelial bodies are polymodal airway sensors: evidence for CO2/H+ sensing. Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15; 308(8):L807-15.
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Zhou Y, Mokhtari RB, Pan J, Cutz E, Yeger H. Carbonic anhydrase II mediates malignant behavior of pulmonary neuroendocrine tumors. Am J Respir Cell Mol Biol. 2015 Feb; 52(2):183-92.
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Livermore S, Pan J, Yeger H, Ratcliffe P, Bishop T, Cutz E. Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice. Adv Exp Med Biol. 2015; 860:309-13.
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Mokhtari RB, Kumar S, Islam SS, Yazdanpanah M, Adeli K, Cutz E, Yeger H. Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines. BMC Cancer. 2013 Aug 08; 13:378.
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Buttigieg J, Pan J, Yeger H, Cutz E. NOX2 (gp91phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 01; 303(7):L598-607.
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