 Choline-Phosphate Cytidylyltransferase
"Choline-Phosphate Cytidylyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.
| Descriptor ID |
D019916
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| MeSH Number(s) |
D08.811.913.696.445.184
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| Concept/Terms |
Choline-Phosphate Cytidylyltransferase- Choline-Phosphate Cytidylyltransferase
- Choline Phosphate Cytidylyltransferase
- Cytidylyltransferase, Choline-Phosphate
- CTP Phosphocholine Cytidylyl-Transferase
- CTP Phosphocholine Cytidylyl Transferase
- Cytidylyl-Transferase, CTP Phosphocholine
- Phosphocholine Cytidylyl-Transferase, CTP
- Phosphorylcholine Cytidyl Transferase
- Cytidyl Transferase, Phosphorylcholine
- Transferase, Phosphorylcholine Cytidyl
- CTP Phosphorylcholine Cytidyltransferase
- Cytidyltransferase, CTP Phosphorylcholine
- Phosphorylcholine Cytidyltransferase, CTP
- Phosphocholine Cytidyltransferase
- Cytidyltransferase, Phosphocholine
- CDP-Choline Synthetase
- CDP Choline Synthetase
- Synthetase, CDP-Choline
- CTP Phosphocholine Cytidylyltransferase
- Cytidylyltransferase, CTP Phosphocholine
- Phosphocholine Cytidylyltransferase, CTP
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Below are MeSH descriptors whose meaning is more general than "Choline-Phosphate Cytidylyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Choline-Phosphate Cytidylyltransferase".
This graph shows the total number of publications written about "Choline-Phosphate Cytidylyltransferase" by people in this website by year, and whether "Choline-Phosphate Cytidylyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Choline-Phosphate Cytidylyltransferase" by people in Profiles.
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Ridsdale R, Tseu I, Wang J, Post M. Functions of membrane binding domain of CTP:phosphocholine cytidylyltransferase in alveolar type II cells. Am J Respir Cell Mol Biol. 2010 Jul; 43(1):74-87.
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Ridsdale R, Tseu I, Roth-Kleiner M, Wang J, Post M. Increased phosphatidylcholine production but disrupted glycogen metabolism in fetal type II cells of mice that overexpress CTP:phosphocholine cytidylyltransferase. J Biol Chem. 2004 Dec 31; 279(53):55946-57.
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Tseu I, Ridsdale R, Liu J, Wang J, Post M. Cell cycle regulation of pulmonary phosphatidylcholine synthesis. Am J Respir Cell Mol Biol. 2002 Apr; 26(4):506-15.
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Ridsdale R, Tseu I, Wang J, Post M. CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues. J Biol Chem. 2001 Dec 28; 276(52):49148-55.
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Yang J, Wang J, Tseu I, Kuliszewski M, Lee W, Post M. Identification of an 11-residue portion of CTP-phosphocholine cytidylyltransferase that is required for enzyme-membrane interactions. Biochem J. 1997 Jul 01; 325 ( Pt 1):29-38.
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Zimmermann LJ, Lee WS, Post M. Regulation of CTP:phosphocholine cytidylyltransferase by cytosolic lipids in rat type II pneumocytes during development. Pediatr Res. 1995 Dec; 38(6):864-9.
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Hogan M, Zimmermann LJ, Wang J, Kuliszewski M, Liu J, Post M. Increased expression of CTP:phosphocholine cytidylyltransferase in maturing type II cells. Am J Physiol. 1994 Jul; 267(1 Pt 1):L25-32.
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Zimmermann LJ, Lee WS, Smith BT, Post M. Cyclic AMP-dependent protein kinase does not regulate CTP:phosphocholine cytidylyltransferase activity in maturing type II cells. Biochim Biophys Acta. 1994 Feb 10; 1211(1):44-50.
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Zimmermann LJ, Hogan M, Carlson KS, Smith BT, Post M. Regulation of phosphatidylcholine synthesis in fetal type II cells by CTP:phosphocholine cytidylyltransferase. Am J Physiol. 1993 Jun; 264(6 Pt 1):L575-80.
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