 Hirschsprung Disease
"Hirschsprung Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Descriptor ID |
D006627
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| MeSH Number(s) |
C06.198.439 C06.405.469.158.701.439 C16.131.314.439
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| Concept/Terms |
Hirschsprung Disease- Hirschsprung Disease
- Disease, Hirschsprung
- Megacolon, Congenital
- Hirschsprung's Disease
- Disease, Hirschsprung's
- Hirschsprungs Disease
- Megacolon, Aganglionic
- Aganglionic Megacolon
- Congenital Megacolon
Aganglionosis, Colonic- Aganglionosis, Colonic
- Colonic Aganglionosis
- Total Colonic Aganglionosis
- Aganglionosis, Total Colonic
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Below are MeSH descriptors whose meaning is more general than "Hirschsprung Disease".
Below are MeSH descriptors whose meaning is more specific than "Hirschsprung Disease".
This graph shows the total number of publications written about "Hirschsprung Disease" by people in this website by year, and whether "Hirschsprung Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 2 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 3 | 1 | 4 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 4 | 1 | 5 | | 2005 | 2 | 0 | 2 | | 2007 | 3 | 0 | 3 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 2 | 0 | 2 | | 2012 | 5 | 1 | 6 | | 2013 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 4 | 0 | 4 | | 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Hirschsprung Disease" by people in Profiles.
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Saadai P, Trappey AF, Goldstein AM, Cowles RA, De La Torre L, Durham MM, Huang EY, Levitt MA, Rialon K, Rollins M, Rothstein DH, Langer JC. Guidelines for the management of postoperative soiling in children with Hirschsprung disease. Pediatr Surg Int. 2019 Aug; 35(8):829-834.
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Masiakos PT, Wales PW. Question-Mark Appearance of the Colon. N Engl J Med. 2019 May 23; 380(21):2051.
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Veras LV, Arnold M, Avansino JR, Bove K, Cowles RA, Durham MM, Goldstein AM, Krishnan C, Langer JC, Levitt M, Monforte-Munoz H, Rabah R, Reyes-Mugica M, Rollins MD, Kapur RP, Gosain A. Guidelines for synoptic reporting of surgery and pathology in Hirschsprung disease. J Pediatr Surg. 2019 Oct; 54(10):2017-2023.
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Cairo SB, Chiu PPL, Dasgupta R, Diefenbach KA, Goldstein AM, Hamilton NA, Lo A, Rollins MD, Rothstein DH. Transitions in care from pediatric to adult general surgery: Evaluating an unmet need for patients with anorectal malformation and Hirschsprung disease. J Pediatr Surg. 2018 Aug; 53(8):1566-1572.
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Seo S, Miyake H, Hock A, Koike Y, Yong C, Lee C, Li B, Pierro A. Duhamel and Transanal Endorectal Pull-throughs for Hirschsprung' Disease: A Systematic Review and Meta-analysis. Eur J Pediatr Surg. 2018 Feb; 28(1):81-88.
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Langer JC, Rollins MD, Levitt M, Gosain A, Torre L, Kapur RP, Cowles RA, Horton J, Rothstein DH, Goldstein AM. Guidelines for the management of postoperative obstructive symptoms in children with Hirschsprung disease. Pediatr Surg Int. 2017 May; 33(5):523-526.
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Gosain A, Frykman PK, Cowles RA, Horton J, Levitt M, Rothstein DH, Langer JC, Goldstein AM. Guidelines for the diagnosis and management of Hirschsprung-associated enterocolitis. Pediatr Surg Int. 2017 May; 33(5):517-521.
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Zani A, Eaton S, Morini F, Puri P, Rintala R, Heurn EV, Lukac M, Bagolan P, Kuebler JF, Friedmacher F, Wijnen R, Tovar JA, Hoellwarth ME, Pierro A. European Paediatric Surgeons' Association Survey on the Management of Hirschsprung Disease. Eur J Pediatr Surg. 2017 Feb; 27(1):96-101.
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Stewart CL, Kulungowski AM, Tong S, Langer JC, Soden J, Sømme S. Rectal biopsies for Hirschsprung disease: Patient characteristics by diagnosis and attending specialty. J Pediatr Surg. 2016 Apr; 51(4):573-6.
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Liu JA, Lai FP, Gui HS, Sham MH, Tam PK, Garcia-Barcelo MM, Hui CC, Ngan ES. Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice. Gastroenterology. 2015 Dec; 149(7):1837-1848.e5.
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