 Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
| Descriptor ID |
D019032
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| MeSH Number(s) |
E05.196.566.755
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| Concept/Terms |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix Assisted Laser Desorption Ionization
- Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
- Matrix Assisted Laser Desorption Ionization Mass Spectrometry
- MALDI
- Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
- MS-MALD
- MALD-MS
- MALDI-MS
- MALDI MS
- Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
- Laser Desorption Ionization Mass Spectrometry, Matrix Assisted
- Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization
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Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in this website by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles.
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Woolman M, Kuzan-Fischer CM, Ferry I, Kiyota T, Luu B, Wu M, Munoz DG, Das S, Aman A, Taylor MD, Rutka JT, Ginsberg HJ, Zarrine-Afsar A. Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales. Cancer Res. 2019 05 01; 79(9):2426-2434.
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Ermini L, Morganti E, Post A, Yeganeh B, Caniggia I, Leadley M, Faria CC, Rutka JT, Post M. Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma. PLoS One. 2017; 12(5):e0176254.
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Heinz A, Schräder CU, Baud S, Keeley FW, Mithieux SM, Weiss AS, Neubert RH, Schmelzer CE. Molecular-level characterization of elastin-like constructs and human aortic elastin. Matrix Biol. 2014 Sep; 38:12-21.
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Forget A, Bihannic L, Cigna SM, Lefevre C, Remke M, Barnat M, Dodier S, Shirvani H, Mercier A, Mensah A, Garcia M, Humbert S, Taylor MD, Lasorella A, Ayrault O. Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors. Dev Cell. 2014 Jun 23; 29(6):649-61.
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Beck J, Maerki S, Posch M, Metzger T, Persaud A, Scheel H, Hofmann K, Rotin D, Pedrioli P, Swedlow JR, Peter M, Sumara I. Ubiquitylation-dependent localization of PLK1 in mitosis. Nat Cell Biol. 2013 Apr; 15(4):430-9.
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Heinz A, Ruttkies CK, Jahreis G, Schräder CU, Wichapong K, Sippl W, Keeley FW, Neubert RH, Schmelzer CE. In vitro cross-linking of elastin peptides and molecular characterization of the resultant biomaterials. Biochim Biophys Acta. 2013 Apr; 1830(4):2994-3004.
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Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, Sanders RW, Moore JP. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. J Biol Chem. 2012 Jul 13; 287(29):24239-54.
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McTaggart LR, Lei E, Richardson SE, Hoang L, Fothergill A, Zhang SX. Rapid identification of Cryptococcus neoformans and Cryptococcus gattii by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol. 2011 Aug; 49(8):3050-3.
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Chae YS, Lee SJ, Moon JH, Kang BW, Kim JG, Sohn SK, Jung JH, Park HY, Park JY, Kim HJ, Lee SW. VARS2 V552V variant as prognostic marker in patients with early breast cancer. Med Oncol. 2011 Dec; 28(4):1273-80.
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Wong DM, Webb JP, Malinowski PM, Macri J, Adeli K. Proteomic profiling of the prechylomicron transport vesicle involved in the assembly and secretion of apoB-48-containing chylomicrons in the intestinal enterocytes. Proteomics. 2009 Jul; 9(14):3698-711.
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