Cystathionine beta-Synthase
"Cystathionine beta-Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.
| Descriptor ID |
D003541
|
| MeSH Number(s) |
D08.811.520.241.300.200
|
| Concept/Terms |
Cystathionine beta-Synthase- Cystathionine beta-Synthase
- Cystathionine beta Synthase
- beta-Synthase, Cystathionine
- Serine Sulfhydrase
- Sulfhydrase, Serine
- Cystathionine Synthetase
- Synthetase, Cystathionine
- beta-Thionase
- beta Thionase
|
Below are MeSH descriptors whose meaning is more general than "Cystathionine beta-Synthase".
Below are MeSH descriptors whose meaning is more specific than "Cystathionine beta-Synthase".
This graph shows the total number of publications written about "Cystathionine beta-Synthase" by people in this website by year, and whether "Cystathionine beta-Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cystathionine beta-Synthase" by people in Profiles.
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Yamada T, Krzeminski M, Bozoky Z, Forman-Kay JD, Strange K. Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel. Biophys J. 2016 Nov 01; 111(9):1876-1886.
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Hubmacher D, Cirulis JT, Miao M, Keeley FW, Reinhardt DP. Functional consequences of homocysteinylation of the elastic fiber proteins fibrillin-1 and tropoelastin. J Biol Chem. 2010 Jan 08; 285(2):1188-98.
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Bocock MA, Zlotkin SH. Hepatic sulfur amino acid metabolism in rats with chronic renal failure. J Nutr. 1990 Jul; 120(7):691-9.