 Sequence Alignment
"Sequence Alignment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
| Descriptor ID |
D016415
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| MeSH Number(s) |
E05.393.751
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| Concept/Terms |
Sequence Alignment- Sequence Alignment
- Alignment, Sequence
- Alignments, Sequence
- Sequence Alignments
Determination, Sequence Homology- Determination, Sequence Homology
- Determinations, Sequence Homology
- Sequence Homology Determinations
- Sequence Homology Determination
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Below are MeSH descriptors whose meaning is more general than "Sequence Alignment".
Below are MeSH descriptors whose meaning is more specific than "Sequence Alignment".
This graph shows the total number of publications written about "Sequence Alignment" by people in this website by year, and whether "Sequence Alignment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 2 | 2 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 2 | 2 | | 1994 | 0 | 3 | 3 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 10 | 10 | | 1997 | 0 | 4 | 4 | | 1998 | 0 | 9 | 9 | | 1999 | 0 | 7 | 7 | | 2000 | 2 | 11 | 13 | | 2001 | 0 | 8 | 8 | | 2002 | 2 | 2 | 4 | | 2003 | 6 | 5 | 11 | | 2004 | 5 | 8 | 13 | | 2005 | 1 | 8 | 9 | | 2006 | 0 | 7 | 7 | | 2007 | 3 | 6 | 9 | | 2008 | 3 | 4 | 7 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 3 | 3 | | 2011 | 0 | 7 | 7 | | 2012 | 0 | 4 | 4 | | 2013 | 0 | 5 | 5 | | 2014 | 2 | 5 | 7 | | 2015 | 0 | 5 | 5 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Sequence Alignment" by people in Profiles.
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Tao P, Sun J, Wu Z, Wang S, Wang J, Li W, Pan H, Bai R, Zhang J, Wang Y, Lee PY, Ying W, Zhou Q, Hou J, Wang W, Sun B, Yang M, Liu D, Fang R, Han H, Yang Z, Huang X, Li H, Deuitch N, Zhang Y, Dissanayake D, Haude K, McWalter K, Roadhouse C, MacKenzie JJ, Laxer RM, Aksentijevich I, Yu X, Wang X, Yuan J, Zhou Q. A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1. Nature. 2020 01; 577(7788):109-114.
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Teyra J, Singer AU, Schmitges FW, Jaynes P, Kit Leng Lui S, Polyak MJ, Fodil N, Krieger JR, Tong J, Schwerdtfeger C, Brasher BB, Ceccarelli DFJ, Moffat J, Sicheri F, Moran MF, Gros P, Eichhorn PJA, Lenter M, Boehmelt G, Sidhu SS. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 2019 04 02; 27(4):590-605.e5.
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Ereño-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP. Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J Mol Biol. 2018 02 02; 430(3):322-336.
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Greb H, Hermann S, Dirks P, Ommen G, Kretschmer V, Schultz K, Zoidl G, Weiler R, Janssen-Bienhold U. Complexity of gap junctions between horizontal cells of the carp retina. Neuroscience. 2017 01 06; 340:8-22.
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Berndt A, Lee SY, Wietek J, Ramakrishnan C, Steinberg EE, Rashid AJ, Kim H, Park S, Santoro A, Frankland PW, Iyer SM, Pak S, Ährlund-Richter S, Delp SL, Malenka RC, Josselyn SA, Carlén M, Hegemann P, Deisseroth K. Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity. Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4):822-9.
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Molinski SV, Ahmadi S, Hung M, Bear CE. Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening. J Biomol Screen. 2015 Dec; 20(10):1204-17.
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Heidari A, Tongsook C, Najafipour R, Musante L, Vasli N, Garshasbi M, Hu H, Mittal K, McNaughton AJ, Sritharan K, Hudson M, Stehr H, Talebi S, Moradi M, Darvish H, Arshad Rafiq M, Mozhdehipanah H, Rashidinejad A, Samiei S, Ghadami M, Windpassinger C, Gillessen-Kaesbach G, Tzschach A, Ahmed I, Mikhailov A, Stavropoulos DJ, Carter MT, Keshavarz S, Ayub M, Najmabadi H, Liu X, Ropers HH, Macheroux P, Vincent JB. Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability. Hum Mol Genet. 2015 Oct 15; 24(20):5697-710.
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Mendoza-Londono R, Fahiminiya S, Majewski J, Tétreault M, Nadaf J, Kannu P, Sochett E, Howard A, Stimec J, Dupuis L, Roschger P, Klaushofer K, Palomo T, Ouellet J, Al-Jallad H, Mort JS, Moffatt P, Boudko S, Bächinger HP, Rauch F. Recessive osteogenesis imperfecta caused by missense mutations in SPARC. Am J Hum Genet. 2015 Jun 04; 96(6):979-85.
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Motta VN, Markle JG, Gulban O, Mortin-Toth S, Liao KC, Mogridge J, Steward CA, Danska JS. Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse. J Immunol. 2015 Jun 15; 194(12):5663-73.
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Vincent A, Forster N, Maynes JT, Paton TA, Billingsley G, Roslin NM, Ali A, Sutherland J, Wright T, Westall CA, Paterson AD, Marshall CR, Héon E. OTX2 mutations cause autosomal dominant pattern dystrophy of the retinal pigment epithelium. J Med Genet. 2014 Dec; 51(12):797-805.
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