 Phagosomes
"Phagosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-bound cytoplasmic vesicles formed by invagination of phagocytized material. They fuse with lysosomes to form phagolysosomes in which the hydrolytic enzymes of the lysosome digest the phagocytized material.
| Descriptor ID |
D010588
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| MeSH Number(s) |
A11.284.430.214.190.875.190.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phagosomes".
Below are MeSH descriptors whose meaning is more specific than "Phagosomes".
This graph shows the total number of publications written about "Phagosomes" by people in this website by year, and whether "Phagosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 3 | 1 | 4 | | 2001 | 3 | 1 | 4 | | 2002 | 2 | 8 | 10 | | 2003 | 6 | 3 | 9 | | 2004 | 4 | 0 | 4 | | 2005 | 5 | 1 | 6 | | 2006 | 3 | 4 | 7 | | 2007 | 7 | 6 | 13 | | 2008 | 5 | 4 | 9 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 2 | 3 | | 2011 | 5 | 1 | 6 | | 2012 | 2 | 3 | 5 | | 2013 | 0 | 2 | 2 | | 2014 | 2 | 2 | 4 | | 2016 | 4 | 0 | 4 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 1 | 4 | | 2019 | 3 | 2 | 5 | | 2020 | 4 | 0 | 4 |
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Below are the most recent publications written about "Phagosomes" by people in Profiles.
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López-Haber C, Levin-Konigsberg R, Zhu Y, Bi-Karchin J, Balla T, Grinstein S, Marks MS, Mantegazza AR. Phosphatidylinositol-4-kinase IIa licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28251-28262.
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Westman J, Walpole GFW, Kasper L, Xue BY, Elshafee O, Hube B, Grinstein S. Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection. Cell Host Microbe. 2020 12 09; 28(6):798-812.e6.
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Walpole GFW, Plumb JD, Chung D, Tang B, Boulay B, Osborne DG, Piotrowski JT, Catz SD, Billadeau DD, Grinstein S, Jaumouillé V. Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation. Cell Rep. 2020 06 02; 31(9):107721.
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Maxson ME, Grinstein S. The Role of Membrane Surface Charge in Phagocytosis. Adv Exp Med Biol. 2020; 1246:43-54.
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Levin-Konigsberg R, Grinstein S. Phagosome-endoplasmic reticulum contacts: Kissing and not running. Traffic. 2020 01; 21(1):172-180.
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Lu Y, Zheng Y, Coyaud É, Zhang C, Selvabaskaran A, Yu Y, Xu Z, Weng X, Chen JS, Meng Y, Warner N, Cheng X, Liu Y, Yao B, Hu H, Xia Z, Muise AM, Klip A, Brumell JH, Girardin SE, Ying S, Fairn GD, Raught B, Sun Q, Neculai D. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019 10 25; 366(6464):460-467.
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Levin-Konigsberg R, Montaño-Rendón F, Keren-Kaplan T, Li R, Ego B, Mylvaganam S, DiCiccio JE, Trimble WS, Bassik MC, Bonifacino JS, Fairn GD, Grinstein S. Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling. Nat Cell Biol. 2019 10; 21(10):1234-1247.
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Ostrowski PP, Freeman SA, Fairn G, Grinstein S. Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides. Dev Cell. 2019 08 19; 50(4):397-410.e3.
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Westman J, Grinstein S, Maxson ME. Revisiting the role of calcium in phagosome formation and maturation. J Leukoc Biol. 2019 10; 106(4):837-851.
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Westman J, Moran G, Mogavero S, Hube B, Grinstein S. Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization. mBio. 2018 09 11; 9(5).
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