 Antimicrobial Cationic Peptides
"Antimicrobial Cationic Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
| Descriptor ID |
D023181
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| MeSH Number(s) |
D12.644.050 D12.776.543.695.054
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| Concept/Terms |
Antimicrobial Cationic Peptides- Antimicrobial Cationic Peptides
- Cationic Peptides, Antimicrobial
- Peptides, Antimicrobial Cationic
- Microbicidal Cationic Proteins
- Cationic Proteins, Microbicidal
- Proteins, Microbicidal Cationic
- Cationic Antimicrobial Peptides
- Antimicrobial Peptides, Cationic
- Peptides, Cationic Antimicrobial
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Below are MeSH descriptors whose meaning is more general than "Antimicrobial Cationic Peptides".
Below are MeSH descriptors whose meaning is more specific than "Antimicrobial Cationic Peptides".
This graph shows the total number of publications written about "Antimicrobial Cationic Peptides" by people in this website by year, and whether "Antimicrobial Cationic Peptides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 2 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antimicrobial Cationic Peptides" by people in Profiles.
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Stone TA, Cole GB, Ravamehr-Lake D, Nguyen HQ, Khan F, Sharpe S, Deber CM. Positive Charge Patterning and Hydrophobicity of Membrane-Active Antimicrobial Peptides as Determinants of Activity, Toxicity, and Pharmacokinetic Stability. J Med Chem. 2019 07 11; 62(13):6276-6286.
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Beaudoin T, Stone TA, Glibowicka M, Adams C, Yau Y, Ahmadi S, Bear CE, Grasemann H, Waters V, Deber CM. Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms. Sci Rep. 2018 10 03; 8(1):14728.
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Sun X, Xiu F, Pan B, Li Y, Haskins JT, Shen W, Li J. Antimicrobial peptide expression in swine granulosa cells in response to lipopolysaccharide. Theriogenology. 2018 Oct 01; 119:80-90.
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Stone TA, Cole GB, Nguyen HQ, Sharpe S, Deber CM. Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides. Bioorg Med Chem. 2018 03 15; 26(6):1189-1196.
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Lavallee CM, MacPherson JAR, Zhou M, Gao Y, Wizzard PR, Wales PW, Turner JM, Willing BP. Lipid Emulsion Formulation of Parenteral Nutrition Affects Intestinal Microbiota and Host Responses in Neonatal Piglets. JPEN J Parenter Enteral Nutr. 2017 11; 41(8):1301-1309.
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Lackraj T, Johnson-Henry K, Sherman PM, Goodman SD, Segall AM, Barnett Foster D. Novel antimicrobial peptide prevents C. rodentium infection in C57BL/6 mice by enhancing acid-induced pathogen killing. Microbiology. 2016 09; 162(9):1641-1650.
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Raqib R, Ly A, Akhtar E, Mily A, Perumal N, Al-Mahmud A, Rekha RS, Hel Baqui A, Roth DE. Prenatal vitamin D3 supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity. Br J Nutr. 2014 Sep 28; 112(6):908-15.
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Walsh P, Vanderlee G, Yau J, Campeau J, Sim VL, Yip CM, Sharpe S. The mechanism of membrane disruption by cytotoxic amyloid oligomers formed by prion protein(106-126) is dependent on bilayer composition. J Biol Chem. 2014 Apr 11; 289(15):10419-30.
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Melino S, Santone C, Di Nardo P, Sarkar B. Histatins: salivary peptides with copper(II)- and zinc(II)-binding motifs: perspectives for biomedical applications. FEBS J. 2014 Feb; 281(3):657-72.
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Yin LM, Lee S, Mak JS, Helmy AS, Deber CM. Differential binding of L- vs. D-isomers of cationic antimicrobial peptides to the biofilm exopolysaccharide alginate. Protein Pept Lett. 2013 Aug; 20(8):843-7.
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