 Autophagy
"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.
| Descriptor ID |
D001343
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| MeSH Number(s) |
G04.299.139.399 G04.299.482.350.091
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| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Autophagocytosis
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Programmed Cell Death
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
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Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 3 | 1 | 4 | | 2009 | 8 | 0 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 7 | 1 | 8 | | 2012 | 10 | 1 | 11 | | 2013 | 3 | 1 | 4 | | 2014 | 2 | 4 | 6 | | 2015 | 6 | 1 | 7 | | 2016 | 3 | 3 | 6 | | 2017 | 2 | 1 | 3 | | 2018 | 0 | 4 | 4 | | 2019 | 2 | 4 | 6 | | 2020 | 1 | 4 | 5 | | 2021 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Autophagy" by people in Profiles.
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McGillis L, Bronte-Tinkew DM, Dang F, Capurro M, Prashar A, Ricciuto A, Greenfield L, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth DE, Griffiths A, Philpott D, Jones NL. Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and "involved" IBD patient intestinal tissues. Am J Physiol Gastrointest Liver Physiol. 2021 08 01; 321(2):G171-G184.
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Akhshi T, Trimble WS. A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy. J Cell Biol. 2021 01 04; 220(1).
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Loredo Martinez M, Zampieri S, Franco C, Ghirardello A, Doria A, Gatto M. Nonimmune mechanisms in idiopathic inflammatory myopathies. Curr Opin Rheumatol. 2020 11; 32(6):515-522.
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Lawson KA, Sousa CM, Zhang X, Kim E, Akthar R, Caumanns JJ, Yao Y, Mikolajewicz N, Ross C, Brown KR, Zid AA, Fan ZP, Hui S, Krall JA, Simons DM, Slater CJ, De Jesus V, Tang L, Singh R, Goldford JE, Martin S, Huang Q, Francis EA, Habsid A, Climie R, Tieu D, Wei J, Li R, Tong AHY, Aregger M, Chan KS, Han H, Wang X, Mero P, Brumell JH, Finelli A, Ailles L, Bader G, Smolen GA, Kingsbury GA, Hart T, Kung C, Moffat J. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Nature. 2020 10; 586(7827):120-126.
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Yamoto M, Alganabi M, Chusilp S, Lee D, Yazaki Y, Lee C, Li B, Pierro A. Lysosomal overloading and necrotizing enterocolitis. Pediatr Surg Int. 2020 Oct; 36(10):1157-1165.
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Chung PED, Gendoo DMA, Ghanbari-Azarnier R, Liu JC, Jiang Z, Tsui J, Wang DY, Xiao X, Li B, Dubuc A, Shih D, Remke M, Ho B, Garzia L, Ben-David Y, Kang SG, Croul S, Haibe-Kains B, Huang A, Taylor MD, Zacksenhaus E. Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy. Nat Commun. 2020 04 14; 11(1):1825.
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Germain K, Kim PK. Pexophagy: A Model for Selective Autophagy. Int J Mol Sci. 2020 Jan 16; 21(2).
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Yamoto M, Lee C, Chusilp S, Yazaki Y, Alganabi M, Li B, Pierro A. The role of autophagy in intestinal epithelial injury. Pediatr Surg Int. 2019 Dec; 35(12):1389-1394.
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Frendo-Cumbo S, Jaldin-Fincati JR, Coyaud E, Laurent EMN, Townsend LK, Tan JMJ, Xavier RJ, Pillon NJ, Raught B, Wright DC, Brumell JH, Klip A. Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation. J Biol Chem. 2019 11 01; 294(44):16172-16185.
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Chong PA, Forman-Kay JD. Oxidative Inhibition of Pbp1 Phase Separation. Biochemistry. 2019 07 16; 58(28):3057-3059.
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