 Autophagy
"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.299.139.399 G04.299.482.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Autophagocytosis
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Programmed Cell Death
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 3 | 1 | 4 | | 2009 | 8 | 0 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 7 | 1 | 8 | | 2012 | 10 | 1 | 11 | | 2013 | 3 | 1 | 4 | | 2014 | 2 | 4 | 6 | | 2015 | 6 | 1 | 7 | | 2016 | 3 | 3 | 6 | | 2017 | 2 | 1 | 3 | | 2018 | 0 | 4 | 4 | | 2019 | 2 | 4 | 6 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Autophagy" by people in Profiles.
-
Chung PED, Gendoo DMA, Ghanbari-Azarnier R, Liu JC, Jiang Z, Tsui J, Wang DY, Xiao X, Li B, Dubuc A, Shih D, Remke M, Ho B, Garzia L, Ben-David Y, Kang SG, Croul S, Haibe-Kains B, Huang A, Taylor MD, Zacksenhaus E. Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy. Nat Commun. 2020 04 14; 11(1):1825.
-
Yamoto M, Lee C, Chusilp S, Yazaki Y, Alganabi M, Li B, Pierro A. The role of autophagy in intestinal epithelial injury. Pediatr Surg Int. 2019 Dec; 35(12):1389-1394.
-
Frendo-Cumbo S, Jaldin-Fincati JR, Coyaud E, Laurent EMN, Townsend LK, Tan JMJ, Xavier RJ, Pillon NJ, Raught B, Wright DC, Brumell JH, Klip A. Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation. J Biol Chem. 2019 11 01; 294(44):16172-16185.
-
Chong PA, Forman-Kay JD. Oxidative Inhibition of Pbp1 Phase Separation. Biochemistry. 2019 07 16; 58(28):3057-3059.
-
Capurro MI, Greenfield LK, Prashar A, Xia S, Abdullah M, Wong H, Zhong XZ, Bertaux-Skeirik N, Chakrabarti J, Siddiqui I, O'Brien C, Dong X, Robinson L, Peek RM, Philpott DJ, Zavros Y, Helmrath M, Jones NL. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nat Microbiol. 2019 08; 4(8):1411-1423.
-
Tan JMJ, Mellouk N, Brumell JH. An autophagy-independent role for ATG16L1: promoting lysosome-mediated plasma membrane repair. Autophagy. 2019 05; 15(5):932-933.
-
Abdullah M, Greenfield LK, Bronte-Tinkew D, Capurro MI, Rizzuti D, Jones NL. VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Sci Rep. 2019 01 10; 9(1):38.
-
Leung CH, Caldarone CA, Guan R, Wen XY, Ailenberg M, Kapus A, Szaszi K, Rotstein OD. Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock. Antioxid Redox Signal. 2019 05 10; 30(14):1760-1773.
-
Tan JMJ, Mellouk N, Osborne SE, Ammendolia DA, Dyer DN, Li R, Brunen D, van Rijn JM, Huang J, Czuczman MA, Cemma MA, Won AM, Yip CM, Xavier RJ, MacDuff DA, Reggiori F, Debnath J, Yoshimori T, Kim PK, Fairn GD, Coyaud E, Raught B, Muise AM, Higgins DE, Brumell JH. An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread. Nat Microbiol. 2018 12; 3(12):1472-1485.
-
Ausman J, Abbade J, Ermini L, Farrell A, Tagliaferro A, Post M, Caniggia I. Ceramide-induced BOK promotes mitochondrial fission in preeclampsia. Cell Death Dis. 2018 02 20; 9(3):298.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|