Monensin
"Monensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
| Descriptor ID |
D008985
|
| MeSH Number(s) |
D03.383.312.600
|
| Concept/Terms |
Monensin Sodium- Monensin Sodium
- Monensin-A-Sodium Complex
- Monensin A Sodium Complex
- Monensin Monosodium Salt
|
Below are MeSH descriptors whose meaning is more general than "Monensin".
Below are MeSH descriptors whose meaning is more specific than "Monensin".
This graph shows the total number of publications written about "Monensin" by people in this website by year, and whether "Monensin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 |
| 1987 | 0 | 1 | 1 |
| 1994 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monensin" by people in Profiles.
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Yu XM, Salter MW. Gain control of NMDA-receptor currents by intracellular sodium. Nature. 1998 Dec 03; 396(6710):469-74.
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Nachliel E, Finkelstein Y, Gutman M. The mechanism of monensin-mediated cation exchange based on real time measurements. Biochim Biophys Acta. 1996 Dec 04; 1285(2):131-45.
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Adeli K. Regulated intracellular degradation of apolipoprotein B in semipermeable HepG2 cells. J Biol Chem. 1994 Mar 25; 269(12):9166-75.
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Grinstein S, Smith JD. Asymmetry of the Na+/H+ antiport of dog red cell ghosts. Sidedness of inhibition by amiloride. J Biol Chem. 1987 Jul 05; 262(19):9088-92.
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Sarkadi B, Attisano L, Grinstein S, Buchwald M, Rothstein A. Volume regulation of Chinese hamster ovary cells in anisoosmotic media. Biochim Biophys Acta. 1984 Jul 25; 774(2):159-68.