 Philipp Maass
| Title | Scientist |
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| Institution | The Hospital for Sick Children |
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| Department | Research Operations |
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| Address | 555 University Avenue
Toronto ON M5G 1X8
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| Phone | 416-813-1500 |
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ORCID
.gif) | 0000-0002-2742-8301  |
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| vCard | Download vCard |
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 Biography | Harvard University, Cambridge, MA | USA | | 2018 | lncRNAs | genome organization | live-cell imaging | | Experimental and Clinical Research Center & Max-Delbrueck-Center for Molecular Medicine, Berlin | Germany | | 2015 | lncRNAs | Molecular Genetics | | Max-Delbrueck-Center for Molecular Medicine, Berlin | Germany | PhD | 10/2009 | Molecular Genetics | | Eberhard Karls University Tuebingen, Tuebingen | Germany | Diploma | 2005 | Virology | Immunology | Human Genetics |
| 2018 | Walter-Siegenthaler Award, Walter-Siegenthaler Society | | 2015 - 2018 | Postdoc fellowship , German Research Foundation (DFG) | | 2013 | National Fellowship Award, European Society of Human Genetics (ESHG) | | 2013 | Best selected talk, German Society of Human Genetics (GfH) | | 2010 | Max Delbrück Center PostDoc fellowship, Max-Delbrück-Center for Molecular Medicine | | 2006 - 2009 | Max Delbrück Center PhD scholarship , Max-Delbrück-Center for Molecular Medicine |
Overview The proper organization of the genome is crucial for the regulation of genes. Interactions between genes and their regulators on the same chromosome are well characterized. Inter-chromosomal contacts between different chromosomes also exist, but their molecular mechanisms remain elusive and obscure. Determining how inter-chromosomal contacts are formed, and how they impact normal and disease states, is critical to better understand the biology and etiology of disease. Dr. Philipp Maass addresses this challenge by using state-of-the-art systems biology. The Maass lab focuses on regions of the non-coding genome that impact development and disease mechanisms in a bedside-to-bench approach.
Research MA-5028/1-2 (PG Maass) German Research Foundation (DFG)
Molecular characterization of cis- and trans-acting gene and ncRNA regulation during human chondrogenesis |
| MA-5028/1-3 (PG Maass) German Research Foundation (DFG)
Molecular characterization of cis- and trans-acting gene and ncRNA regulation during human chondrogenesis |
| MA-5028/2-1 (PG Maass) German Research Foundation (DFG)
Functional characterization of mesenchymal stem cell-derived lncRNAs |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Mattioli K, Volders PJ, Gerhardinger C, Lee JC, Maass PG, Melé M, Rinn JL. High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity. Genome Res. 2019 03; 29(3):344-355. PMID: 30683753.
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Maass PG, Barutcu AR, Rinn JL. Interchromosomal interactions: A genomic love story of kissing chromosomes. J Cell Biol. 2019 Jan 07; 218(1):27-38. PMID: 30181316.
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Maass PG, Weise A, Rittscher K, Lichtenwald J, Barutcu AR, Liehr T, Aydin A, Wefeld-Neuenfeld Y, Pölsler L, Tinschert S, Rinn JL, Luft FC, Bähring S. Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome. EMBO J. 2018 Aug 01; 37(15). PMID: 29921581.
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Barutcu AR, Maass PG, Lewandowski JP, Weiner CL, Rinn JL. A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus. Nat Commun. 2018 04 13; 9(1):1444. PMID: 29654311.
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Maass PG, Barutcu AR, Weiner CL, Rinn JL. Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C. Mol Cell. 2018 03 15; 69(6):1039-1045.e3. PMID: 29526697.
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Shukla CJ, McCorkindale AL, Gerhardinger C, Korthauer KD, Cabili MN, Shechner DM, Irizarry RA, Maass PG, Rinn JL. High-throughput identification of RNA nuclear enrichment sequences. EMBO J. 2018 03 15; 37(6). PMID: 29335281.
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Maass PG, Barutcu AR, Shechner DM, Weiner CL, Melé M, Rinn JL. Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING). Nat Struct Mol Biol. 2018 Feb; 25(2):176-184. PMID: 29343869.
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Maass PG, Glažar P, Memczak S, Dittmar G, Hollfinger I, Schreyer L, Sauer AV, Toka O, Aiuti A, Luft FC, Rajewsky N. A map of human circular RNAs in clinically relevant tissues. J Mol Med (Berl). 2017 11; 95(11):1179-1189. PMID: 28842720.
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Eulenberg-Gustavus C, Bähring S, Maass PG, Luft FC, Kettritz R. Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets. J Exp Med. 2017 Jul 03; 214(7):2089-2101. PMID: 28559244.
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Toka O, Tank J, Schächterle C, Aydin A, Maass PG, Elitok S, Bartels-Klein E, Hollfinger I, Lindschau C, Mai K, Boschmann M, Rahn G, Movsesian MA, Müller T, Doescher A, Gnoth S, Mühl A, Toka HR, Wefeld-Neuenfeld Y, Utz W, Töpper A, Jordan J, Schulz-Menger J, Klussmann E, Bähring S, Luft FC. Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly. Hypertension. 2015 Oct; 66(4):800-8. PMID: 26283042.
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Maass PG, Aydin A, Luft FC, Schächterle C, Weise A, Stricker S, Lindschau C, Vaegler M, Qadri F, Toka HR, Schulz H, Krawitz PM, Parkhomchuk D, Hecht J, Hollfinger I, Wefeld-Neuenfeld Y, Bartels-Klein E, Mühl A, Kann M, Schuster H, Chitayat D, Bialer MG, Wienker TF, Ott J, Rittscher K, Liehr T, Jordan J, Plessis G, Tank J, Mai K, Naraghi R, Hodge R, Hopp M, Hattenbach LO, Busjahn A, Rauch A, Vandeput F, Gong M, Rüschendorf F, Hübner N, Haller H, Mundlos S, Bilginturan N, Movsesian MA, Klussmann E, Toka O, Bähring S. PDE3A mutations cause autosomal dominant hypertension with brachydactyly. Nat Genet. 2015 Jun; 47(6):647-53. PMID: 25961942.
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Maass PG, Luft FC, Bähring S. Long non-coding RNA in health and disease. J Mol Med (Berl). 2014 Apr; 92(4):337-46. PMID: 24531795.
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Maass PG, Rump A, Schulz H, Stricker S, Schulze L, Platzer K, Aydin A, Tinschert S, Goldring MB, Luft FC, Bähring S. A misplaced lncRNA causes brachydactyly in humans. J Clin Invest. 2012 Nov; 122(11):3990-4002. PMID: 23093776; PMCID: PMC3485082.
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Toka O, Maass PG, Aydin A, Toka H, Hübner N, Rüschendorf F, Gong M, Luft FC, Bähring S. Childhood hypertension in autosomal-dominant hypertension with brachydactyly. Hypertension. 2010 Nov; 56(5):988-94. PMID: 20837885.
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Maass PG, Wirth J, Aydin A, Rump A, Stricker S, Tinschert S, Otero M, Tsuchimochi K, Goldring MB, Luft FC, Bähring S. A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E. Hum Mol Genet. 2010 Mar 01; 19(5):848-60. PMID: 20015959; PMCID: PMC3031338.
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Naumann U, Maass P, Gleske AK, Aulwurm S, Weller M, Eisele G. Glioma gene therapy with soluble transforming growth factor-beta receptors II and III. Int J Oncol. 2008 Oct; 33(4):759-65. PMID: 18813789.
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Bähring S, Kann M, Neuenfeld Y, Gong M, Chitayat D, Toka HR, Toka O, Plessis G, Maass P, Rauch A, Aydin A, Luft FC. Inversion region for hypertension and brachydactyly on chromosome 12p features multiple splicing and noncoding RNA. Hypertension. 2008 Feb; 51(2):426-31. PMID: 18086950.
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Barta P, Monti J, Maass PG, Gorzelniak K, Müller DN, Dechend R, Luft FC, Hübner N, Sharma AM. A gene expression analysis in rat kidney following high and low salt intake. J Hypertens. 2002 Jun; 20(6):1115-20. PMID: 12023680.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2002 | 1 | | 2007 | 1 | | 2008 | 1 | | 2009 | 1 | | 2010 | 1 | | 2012 | 1 | | 2014 | 1 | | 2015 | 2 | | 2017 | 2 | | 2018 | 6 | | 2019 | 1 |
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