 Apolipoproteins B
"Apolipoproteins B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
| Descriptor ID |
D001055
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| MeSH Number(s) |
D10.532.091.300 D12.776.070.400.300 D12.776.521.120.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apolipoproteins B".
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This graph shows the total number of publications written about "Apolipoproteins B" by people in this website by year, and whether "Apolipoproteins B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 1 | 2 | | 1992 | 4 | 0 | 4 | | 1993 | 2 | 0 | 2 | | 1994 | 1 | 0 | 1 | | 1995 | 3 | 0 | 3 | | 1996 | 1 | 0 | 1 | | 1997 | 4 | 0 | 4 | | 1998 | 4 | 0 | 4 | | 1999 | 2 | 0 | 2 | | 2000 | 3 | 1 | 4 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 4 | 5 | | 2003 | 0 | 2 | 2 | | 2004 | 8 | 1 | 9 | | 2005 | 4 | 0 | 4 | | 2006 | 3 | 0 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 3 | 4 | | 2012 | 1 | 2 | 3 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apolipoproteins B" by people in Profiles.
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Su Q, Baker C, Christian P, Naples M, Tong X, Zhang K, Santha M, Adeli K. Hepatic mitochondrial and ER stress induced by defective PPARa signaling in the pathogenesis of hepatic steatosis. Am J Physiol Endocrinol Metab. 2014 Jun 01; 306(11):E1264-73.
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Christian P, Sacco J, Adeli K. Autophagy: Emerging roles in lipid homeostasis and metabolic control. Biochim Biophys Acta. 2013 Apr; 1831(4):819-24.
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Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2104-12.
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Xiao C, Bandsma RH, Dash S, Szeto L, Lewis GF. Exenatide, a glucagon-like peptide-1 receptor agonist, acutely inhibits intestinal lipoprotein production in healthy humans. Arterioscler Thromb Vasc Biol. 2012 Jun; 32(6):1513-9.
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Adeli K. Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules. Am J Physiol Endocrinol Metab. 2011 Dec; 301(6):E1051-64.
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Karimian Pour N, Adeli K. Insulin silences apolipoprotein B mRNA translation by inducing intracellular traffic into cytoplasmic RNA granules. Biochemistry. 2011 Aug 16; 50(32):6942-50.
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Boros CA, Bradley TJ, Cheung MM, Bargman JM, Russell JL, McCrindle BW, Adeli K, Hamilton J, Silverman ED. Early determinants of atherosclerosis in paediatric systemic lupus erythematosus. Clin Exp Rheumatol. 2011 May-Jun; 29(3):575-81.
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Xiao C, Hsieh J, Adeli K, Lewis GF. Gut-liver interaction in triglyceride-rich lipoprotein metabolism. Am J Physiol Endocrinol Metab. 2011 Sep; 301(3):E429-46.
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Taylor A, Wang D, Patel K, Whittall R, Wood G, Farrer M, Neely RD, Fairgrieve S, Nair D, Barbir M, Jones JL, Egan S, Everdale R, Lolin Y, Hughes E, Cooper JA, Hadfield SG, Norbury G, Humphries SE. Mutation detection rate and spectrum in familial hypercholesterolaemia patients in the UK pilot cascade project. Clin Genet. 2010 Jun; 77(6):572-80.
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Su Q, Tsai J, Xu E, Qiu W, Bereczki E, Santha M, Adeli K. Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology. 2009 Jul; 50(1):77-84.
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