 Hydroxyeicosatetraenoic Acids
"Hydroxyeicosatetraenoic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.
| Descriptor ID |
D006893
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| MeSH Number(s) |
D10.251.355.255.100.300 D10.251.355.310.166.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydroxyeicosatetraenoic Acids".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyeicosatetraenoic Acids".
This graph shows the total number of publications written about "Hydroxyeicosatetraenoic Acids" by people in this website by year, and whether "Hydroxyeicosatetraenoic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 2 | 0 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydroxyeicosatetraenoic Acids" by people in Profiles.
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Pace-Asciak CR. Novel eicosanoid pathways: the discovery of prostacyclin/6-keto prostaglandin F1alpha and the hepoxilins. Mol Neurobiol. 2005 Aug; 32(1):19-26.
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Vogan CL, Maskrey BH, Taylor GW, Henry S, Pace-Asciak CR, Clare AS, Rowley AF. Hepoxilins and trioxilins in barnacles: an analysis of their potential roles in egg hatching and larval settlement. J Exp Biol. 2003 Sep; 206(Pt 18):3219-26.
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Reynaud D, Sun A, Demin P, Pace-Asciak CR. Novel platelet antiaggregating substances. Biochem Biophys Res Commun. 2001 Jun 15; 284(3):580-2.
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Reynaud D, Pace-Asciak CR. Docosahexaenoic acid causes accumulation of free arachidonic acid in rat pineal gland and hippocampus to form hepoxilins from both substrates. Biochim Biophys Acta. 1997 Jun 23; 1346(3):305-16.
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Demin P, Reynaud D, Pace-Asciak CR. Extractive derivatization of the 12-lipoxygenase products, hepoxilins, and related compounds into fluorescent anthryl esters for their complete high-performance liquid chromatography profiling in biological systems. Anal Biochem. 1995 Apr 10; 226(2):252-5.
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Lin Z, Laneuville O, Pace-Asciak CR. Hepoxilin A3 induces heat shock protein (HSP72) expression in human neutrophils. Biochem Biophys Res Commun. 1991 Aug 30; 179(1):52-6.
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Pace-Asciak CR, Asotra S, Pellerin L, Wolfe LS, Corey EJ, Wu P, Gurevich N, Carlen PL. Brain hepoxilins: formation and action. Adv Prostaglandin Thromboxane Leukot Res. 1989; 19:141-7.
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Pace-Asciak CR. Formation and metabolism of hepoxilin A3 by the rat brain. Biochem Biophys Res Commun. 1988 Feb 29; 151(1):493-8.
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Pace-Asciak CR. Formation of hepoxilin A4, B4 and the corresponding trioxilins from 12(S)-hydroperoxy-5,8,10,14,17-icosapentaenoic acid. Prostaglandins Leukot Med. 1986 Apr; 22(1):1-9.
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Pace-Asciak CR, Martin JM, Corey EJ. Hepoxilins, potential endogenous mediators of insulin release. Prog Lipid Res. 1986; 25(1-4):625-8.
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