 Area Under Curve
"Area Under Curve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
| Descriptor ID |
D019540
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| MeSH Number(s) |
E05.318.740.200 G03.787.101 G07.690.725.064 N06.850.520.830.200
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| Concept/Terms |
Area Under Curve- Area Under Curve
- Area Under Curves
- Curve, Area Under
- Curves, Area Under
- Under Curve, Area
- Under Curves, Area
- AUC
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Below are MeSH descriptors whose meaning is more general than "Area Under Curve".
Below are MeSH descriptors whose meaning is more specific than "Area Under Curve".
This graph shows the total number of publications written about "Area Under Curve" by people in this website by year, and whether "Area Under Curve" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 2000 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 4 | 4 | | 2007 | 0 | 3 | 3 | | 2008 | 1 | 3 | 4 | | 2009 | 0 | 4 | 4 | | 2010 | 1 | 3 | 4 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 3 | 3 | | 2013 | 0 | 7 | 7 | | 2014 | 0 | 3 | 3 | | 2015 | 0 | 4 | 4 | | 2016 | 0 | 6 | 6 | | 2017 | 0 | 7 | 7 | | 2018 | 0 | 5 | 5 | | 2019 | 1 | 2 | 3 |
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Below are the most recent publications written about "Area Under Curve" by people in Profiles.
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Arrieta AC, Sung L, Bradley JS, Zwaan CM, Gates D, Waskin H, Carmelitano P, Groll AH, Lehrnbecher T, Mangin E, Joshi A, Kartsonis NA, Walsh TJ, Paschke A. A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia. PLoS One. 2019; 14(3):e0212837.
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Patel P, Nathan PC, Walker SE, Zupanec S, Volpe J, Dupuis LL. Relative bioavailability of an extemporaneously prepared aprepitant oral suspension in healthy adults. J Oncol Pharm Pract. 2019 Dec; 25(8):1907-1915.
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El-Matary W, Walters TD, Huynh HQ, deBruyn J, Mack DR, Jacobson K, Sherlock ME, Church P, Wine E, Carroll MW, Benchimol EI, Lawrence S, Griffiths AM. Higher Postinduction Infliximab Serum Trough Levels Are Associated With Healing of Fistulizing Perianal Crohn's Disease in Children. Inflamm Bowel Dis. 2019 01 01; 25(1):150-155.
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Delaney SR, Malik PRV, Stefan C, Edginton AN, Colantonio DA, Ito S. Predicting Escitalopram Exposure to Breastfeeding Infants: Integrating Analytical and In Silico Techniques. Clin Pharmacokinet. 2018 12; 57(12):1603-1611.
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Payne BA, Ryan H, Bone J, Magee LA, Aarvold AB, Mark Ansermino J, Bhutta ZA, Bowen M, Guilherme Cecatti J, Chazotte C, Crozier T, de Pont AJM, Demirkiran O, Duan T, Kallen M, Ganzevoort W, Geary M, Goffman D, Hutcheon JA, Joseph KS, Lapinsky SE, Lataifeh I, Li J, Liskonova S, Hamel EM, McAuliffe FM, O'Herlihy C, Mol BWJ, Seaward PGR, Tadros R, Togal T, Qureshi R, Vivian Ukah U, Vasquez D, Wallace E, Yong P, Zhou V, Walley KR, von Dadelszen P. Development and internal validation of the multivariable CIPHER (Collaborative Integrated Pregnancy High-dependency Estimate of Risk) clinical risk prediction model. Crit Care. 2018 Oct 30; 22(1):278.
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Lee GW, Park SW, Go SI, Kim HG, Kim MK, Min CK, Kwak JY, Bae SB, Yoon SS, Lee JJ, Kim KH, Nam SH, Mun YC, Kim HJ, Bae SH, Shin HJ, Lee JH, Park JS, Jeong SH, Lee MH, Lee HS, Park KW, Lee WS, Lee SM, Lee JO, Hyun MS, Jo DY, Lim SN, Lee JH, Kim H, Cho DY, Do YR, Kim JA, Park SK, Kim JS, Kim SJ, Yi HG, Moon JH, Choi CW, Kim SH, Kim BS, Park MR, Shim H, Song MK, Kim Y, Kim K. The Derived Neutrophil-to-Lymphocyte Ratio Is an Independent Prognostic Factor in Transplantation Ineligible Patients with Multiple Myeloma. Acta Haematol. 2018; 140(3):146-156.
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McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer M, Thomas CJ, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA. Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma. Oncogene. 2018 05; 37(20):2630-2644.
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Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H, Hough T, Mallon AM, Wells S, Santos L, Lelliott CJ, White JK, Sorg T, Champy MF, Bower LR, Reynolds CL, Flenniken AM, Murray SA, Nutter LMJ, Svenson KL, West D, Tocchini-Valentini GP, Beaudet AL, Bosch F, Braun RB, Dobbie MS, Gao X, Herault Y, Moshiri A, Moore BA, Kent Lloyd KC, McKerlie C, Masuya H, Tanaka N, Flicek P, Parkinson HE, Sedlacek R, Seong JK, Wang CL, Moore M, Brown SD, Tschöp MH, Wurst W, Klingenspor M, Wolf E, Beckers J, Machicao F, Peter A, Staiger H, Häring HU, Grallert H, Campillos M, Maier H, Fuchs H, Gailus-Durner V, Werner T, Hrabe de Angelis M. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nat Commun. 2018 01 18; 9(1):288.
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Samuels-Kalow M, Peltz A, Rodean J, Hall M, Alpern ER, Aronson PL, Berry JG, Shaw KN, Morse RB, Freedman SB, Cohen E, Simon HK, Shah SS, Katsogridakis Y, Neuman MI. Predicting Low-Resource-Intensity Emergency Department Visits in Children. Acad Pediatr. 2018 04; 18(3):297-304.
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Marcovecchio ML, Chiesa ST, Bond S, Daneman D, Dawson S, Donaghue KC, Jones TW, Mahmud FH, Marshall SM, Neil HAW, Dalton RN, Deanfield J, Dunger DB. ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes. N Engl J Med. 2017 11 02; 377(18):1733-1745.
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