 Leukotriene B4
"Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D007975
|
| MeSH Number(s) |
D10.251.355.255.100.450.411 D10.251.355.310.166.887.411 D23.469.050.175.450.415
|
| Concept/Terms |
Leukotriene B4- Leukotriene B4
- Leukotriene B-4
- B-4, Leukotriene
- Leukotriene B 4
- LTB4
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene B4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene B4".
This graph shows the total number of publications written about "Leukotriene B4" by people in this website by year, and whether "Leukotriene B4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1993 | 1 | 0 | 1 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukotriene B4" by people in Profiles.
-
Otulakowski G, Engelberts D, Arima H, Hirate H, Bayir H, Post M, Kavanagh BP. a-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury. Thorax. 2017 06; 72(6):538-549.
-
Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, Brown GE, Yaffe MB, Plumb J, Grinstein S, Glogauer M, Gelb MH. Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. J Biol Chem. 2005 Mar 04; 280(9):7519-29.
-
Pace-Asciak CR, Reynaud D, Rounova O, Demin P, Pivnitsky KK. Hepoxilin A3 is metabolized into its omega-hydroxy metabolite by human neutrophils. Adv Exp Med Biol. 1999; 469:535-8.
-
Reynaud D, Rounova O, Demin PM, Pivnitsky KK, Pace-Asciak CR. Hepoxilin A3 is oxidized by human neutrophils into its omega-hydroxy metabolite by an activity independent of LTB4 omega-hydroxylase. Biochim Biophys Acta. 1997 Oct 18; 1348(3):287-98.
-
Pace-Asciak CR, Reynaud D, Laneuville O, Grinstein S, Nigam S. Hepoxilin A3 inhibits agonist-evoked rise in free intracellular calcium in human neutrophils. Adv Exp Med Biol. 1997; 400A:375-80.
-
Laneuville O, Reynaud D, Grinstein S, Nigam S, Pace-Asciak CR. Hepoxilin A3 inhibits the rise in free intracellular calcium evoked by formyl-methionyl-leucyl-phenylalanine, platelet-activating factor and leukotriene B4. Biochem J. 1993 Oct 15; 295 ( Pt 2):393-7.
-
Mack DR, Lau AS, Sherman PM. Systemic tumor necrosis factor-alpha production in experimental colitis. Dig Dis Sci. 1992 Nov; 37(11):1738-45.
-
Mack DR, Gaginella TS, Sherman PM. Effect of colonic inflammation on mucin inhibition of Escherichia coli RDEC-1 binding in vitro. Gastroenterology. 1992 Apr; 102(4 Pt 1):1199-211.
-
Lu DJ, Grinstein S. ATP and guanine nucleotide dependence of neutrophil activation. Evidence for the involvement of two distinct GTP-binding proteins. J Biol Chem. 1990 Aug 15; 265(23):13721-9.
-
Nasmith PE, Grinstein S. Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils. Biosci Rep. 1988 Feb; 8(1):65-76.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|