 Up-Regulation
"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
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| MeSH Number(s) |
G02.111.087.880 G02.149.115.880 G05.355.315.850 G07.690.773.998
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| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
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Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 5 | 6 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 6 | 6 | | 2005 | 1 | 3 | 4 | | 2006 | 0 | 6 | 6 | | 2007 | 0 | 4 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 1 | 6 | 7 | | 2010 | 0 | 9 | 9 | | 2011 | 2 | 11 | 13 | | 2012 | 1 | 11 | 12 | | 2013 | 2 | 5 | 7 | | 2014 | 0 | 5 | 5 | | 2015 | 0 | 7 | 7 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 9 | 9 | | 2018 | 0 | 11 | 11 | | 2019 | 2 | 4 | 6 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. The white matter is a pro-differentiative niche for glioblastoma. Nat Commun. 2021 04 12; 12(1):2184.
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Ryall S, Tabori U, Hawkins C. Pediatric low-grade glioma in the era of molecular diagnostics. Acta Neuropathol Commun. 2020 03 12; 8(1):30.
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Lock MC, Tellam RL, Darby JRT, Soo JY, Brooks DA, Macgowan CK, Selvanayagam JB, Porrello ER, Seed M, Keller-Wood M, Morrison JL. Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart. Physiol Genomics. 2020 03 01; 52(3):143-159.
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Alganabi M, Zhu H, O'Connell JS, Biouss G, Zito A, Li B, Bindi E, Pierro A. Calcium/calmodulin-dependent protein kinase IV signaling pathway is upregulated in experimental necrotizing enterocolitis. Pediatr Surg Int. 2020 Mar; 36(3):271-277.
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Lee C, Lau E, Chusilp S, Filler R, Li B, Zhu H, Yamoto M, Pierro A. Protective effects of vitamin D against injury in intestinal epithelium. Pediatr Surg Int. 2019 Dec; 35(12):1395-1401.
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Robinson MH, Maximov V, Lallani S, Farooq H, Taylor MD, Read RD, Kenney AM. Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. Sci Rep. 2019 09 20; 9(1):13611.
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Musa J, Cidre-Aranaz F, Aynaud MM, Orth MF, Knott MML, Mirabeau O, Mazor G, Varon M, Hölting TLB, Grossetête S, Gartlgruber M, Surdez D, Gerke JS, Ohmura S, Marchetto A, Dallmayer M, Baldauf MC, Stein S, Sannino G, Li J, Romero-Pérez L, Westermann F, Hartmann W, Dirksen U, Gymrek M, Anderson ND, Shlien A, Rotblat B, Kirchner T, Delattre O, Grünewald TGP. Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. Nat Commun. 2019 09 11; 10(1):4128.
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Robinson CM, Poon BPK, Kano Y, Pluthero FG, Kahr WHA, Ohh M. A Hypoxia-Inducible HIF1-GAL3ST1-Sulfatide Axis Enhances ccRCC Immune Evasion via Increased Tumor Cell-Platelet Binding. Mol Cancer Res. 2019 11; 17(11):2306-2317.
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Liu J, Zhu H, Li B, Robinson SC, Lee C, O'Connell JS, Bindi E, Zheng S, Sherman PM, Pierro A. Lactoferrin Reduces Necrotizing Enterocolitis Severity by Upregulating Intestinal Epithelial Proliferation. Eur J Pediatr Surg. 2020 Feb; 30(1):90-95.
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Kemaladewi DU, Bassi PS, Erwood S, Al-Basha D, Gawlik KI, Lindsay K, Hyatt E, Kember R, Place KM, Marks RM, Durbeej M, Prescott SA, Ivakine EA, Cohn RD. A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene. Nature. 2019 08; 572(7767):125-130.
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