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Kathene Johnson-Henry

TitleOperations Manager (PM)
InstitutionThe Hospital for Sick Children
DepartmentGastroenterology, Hepatology and Nutrition
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
ORCID ORCID Icon0000-0002-6046-550X Additional info
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wu RY, Li B, Koike Y, Määttänen P, Miyake H, Cadete M, Johnson-Henry KC, Botts SR, Lee C, Abrahamsson TR, Landberg E, Pierro A, Sherman PM. Human Milk Oligosaccharides Increase Mucin Expression in Experimental Necrotizing Enterocolitis. Mol Nutr Food Res. 2019 02; 63(3):e1800658. PMID: 30407734.
      View in: PubMed
    2. Määttänen P, Lurz E, Botts SR, Wu RY, Yeung CW, Li B, Abiff S, Johnson-Henry KC, Lepp D, Power KA, Pierro A, Surette ME, Sherman PM. Ground flaxseed reverses protection of a reduced-fat diet against Citrobacter rodentium-induced colitis. Am J Physiol Gastrointest Liver Physiol. 2018 Nov 01; 315(5):G788-G798. PMID: 30095298.
      View in: PubMed
    3. Wu RY, Määttänen P, Napper S, Scruten E, Li B, Koike Y, Johnson-Henry KC, Pierro A, Rossi L, Botts SR, Surette MG, Sherman PM. Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota. Microbiome. 2017 10 10; 5(1):135. PMID: 29017607.
      View in: PubMed
    4. Wu RY, Abdullah M, Määttänen P, Pilar AV, Scruten E, Johnson-Henry KC, Napper S, O'Brien C, Jones NL, Sherman PM. Protein kinase C d signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function. Sci Rep. 2017 01 18; 7:40820. PMID: 28098206.
      View in: PubMed
    5. Johnson-Henry KC, Abrahamsson TR, Wu RY, Sherman PM. Probiotics, Prebiotics, and Synbiotics for the Prevention of Necrotizing Enterocolitis. Adv Nutr. 2016 09; 7(5):928-37. PMID: 27633108.
      View in: PubMed
    6. Lackraj T, Johnson-Henry K, Sherman PM, Goodman SD, Segall AM, Barnett Foster D. Novel antimicrobial peptide prevents C. rodentium infection in C57BL/6 mice by enhancing acid-induced pathogen killing. Microbiology. 2016 09; 162(9):1641-1650. PMID: 27412446.
      View in: PubMed
    7. Richard Y. Wu, Michael P. Jeffery, Kathene C. Johnson-Henry, Julia M. Green-Johnson, and Philip M. Sherman. Prebiotic and probiotic effects on host immunity. Lymphosign. 2016.
      View Publication
    8. Howe KL, Lorentz RJ, Assa A, Pinnell LJ, Johnson-Henry KC, Sherman PM. Transforming growth factor-ß1 protects against intestinal epithelial barrier dysfunction caused by hypoxia-reoxygenation. Shock. 2015 May; 43(5):483-9. PMID: 25608140.
      View in: PubMed
    9. Yusta B, Baggio LL, Koehler J, Holland D, Cao X, Pinnell LJ, Johnson-Henry KC, Yeung W, Surette MG, Bang KW, Sherman PM, Drucker DJ. GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R. Diabetes. 2015 Jul; 64(7):2537-49. PMID: 25735732.
      View in: PubMed
    10. Assa A, Vong L, Pinnell LJ, Rautava J, Avitzur N, Johnson-Henry KC, Sherman PM. Vitamin D deficiency predisposes to adherent-invasive Escherichia coli-induced barrier dysfunction and experimental colonic injury. Inflamm Bowel Dis. 2015 Feb; 21(2):297-306. PMID: 25590952.
      View in: PubMed
    11. Johnson-Henry KC, Pinnell LJ, Waskow AM, Irrazabal T, Martin A, Hausner M, Sherman PM. Short-chain fructo-oligosaccharide and inulin modulate inflammatory responses and microbial communities in Caco2-bbe cells and in a mouse model of intestinal injury. J Nutr. 2014 Nov; 144(11):1725-33. PMID: 25143376.
      View in: PubMed
    12. Assa A, Vong L, Pinnell LJ, Avitzur N, Johnson-Henry KC, Sherman PM. Vitamin D deficiency promotes epithelial barrier dysfunction and intestinal inflammation. J Infect Dis. 2014 Oct 15; 210(8):1296-305. PMID: 24755435.
      View in: PubMed
    13. Shen-Tu G, Kim H, Liu M, Johnson-Henry KC, Sherman PM. Protein kinase C mediates enterohemorrhagic Escherichia coli O157:H7-induced attaching and effacing lesions. Infect Immun. 2014 Apr; 82(4):1648-56. PMID: 24491575; PMCID: PMC3993376.
      View in: PubMed, PubMed Central
    14. Ho NK, Hawley SP, Ossa JC, Mathieu O, Tompkins TA, Johnson-Henry KC, Sherman PM. Immune signalling responses in intestinal epithelial cells exposed to pathogenic Escherichia coli and lactic acid-producing probiotics. Benef Microbes. 2013 Jun 01; 4(2):195-209. PMID: 23443951.
      View in: PubMed
    15. Ho NK, Henry AC, Johnson-Henry K, Sherman PM. Pathogenicity, host responses and implications for management of enterohemorrhagic Escherichia coli O157:H7 infection. Can J Gastroenterol. 2013; 27(5):281-5. PMID: 23712303; PMCID: PMC3735731.
      View in: PubMed, PubMed Central
    16. Rodrigues DM, Sousa AJ, Hawley SP, Vong L, Gareau MG, Kumar SA, Johnson-Henry KC, Sherman PM. Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis. BMC Microbiol. 2012 Jun 13; 12:105. PMID: 22694805; PMCID: PMC3676156.
      View in: PubMed, PubMed Central
    17. Ho NK, Ossa JC, Silphaduang U, Johnson R, Johnson-Henry KC, Sherman PM. Enterohemorrhagic Escherichia coli O157:H7 Shiga toxins inhibit gamma interferon-mediated cellular activation. Infect Immun. 2012 Jul; 80(7):2307-15. PMID: 22526675; PMCID: PMC3416474.
      View in: PubMed, PubMed Central
    18. Rodrigues DM, Sousa AJ, Johnson-Henry KC, Sherman PM, Gareau MG. Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice. J Infect Dis. 2012 Jul 01; 206(1):99-109. PMID: 22430833.
      View in: PubMed
    19. Wine E, Gareau MG, Johnson-Henry K, Sherman PM. Strain-specific probiotic (Lactobacillus helveticus) inhibition of Campylobacter jejuni invasion of human intestinal epithelial cells. FEMS Microbiol Lett. 2009 Nov; 300(1):146-52. PMID: 19765084.
      View in: PubMed
    20. Sherman PM, Ossa JC, Johnson-Henry K. Unraveling mechanisms of action of probiotics. Nutr Clin Pract. 2009 Feb-Mar; 24(1):10-4. PMID: 19244144.
      View in: PubMed
    21. Jandu N, Zeng ZJ, Johnson-Henry KC, Sherman PM. Probiotics prevent enterohaemorrhagic Escherichia coli O157:H7-mediated inhibition of interferon-gamma-induced tyrosine phosphorylation of STAT-1. Microbiology. 2009 Feb; 155(Pt 2):531-40. PMID: 19202101.
      View in: PubMed
    22. Philip M Sherman, Kathene Johnson-Henry, and Stanley Zlotkin. Role of probiotics in promoting gastrointestinal health and physical development. Nutrition Reviews. 2009; 1(67):43-45.
      View Publication
    23. Donato KA, Zareie M, Jassem AN, Jandu N, Alingary N, Carusone SC, Johnson-Henry KC, Sherman PM. Escherichia albertii and Hafnia alvei are candidate enteric pathogens with divergent effects on intercellular tight junctions. Microb Pathog. 2008 Nov-Dec; 45(5-6):377-85. PMID: 18930803.
      View in: PubMed
    24. Johnson-Henry KC, Donato KA, Shen-Tu G, Gordanpour M, Sherman PM. Lactobacillus rhamnosus strain GG prevents enterohemorrhagic Escherichia coli O157:H7-induced changes in epithelial barrier function. Infect Immun. 2008 Apr; 76(4):1340-8. PMID: 18227169; PMCID: PMC2292865.
      View in: PubMed, PubMed Central
    25. Kathene C Johnson-Henry and Philip M Sherman. Exploring Frontiers of New Probiotic and Pharmabiotic Therapies. Nutrafoods. 2008; 2/3(7):27-36.
    26. Johnson-Henry KC, Hagen KE, Gordonpour M, Tompkins TA, Sherman PM. Surface-layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells. Cell Microbiol. 2007 Feb; 9(2):356-67. PMID: 16925785.
      View in: PubMed
    27. Zareie M, Johnson-Henry K, Jury J, Yang PC, Ngan BY, McKay DM, Soderholm JD, Perdue MH, Sherman PM. Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress. Gut. 2006 Nov; 55(11):1553-60. PMID: 16638791; PMCID: PMC1860130.
      View in: PubMed, PubMed Central
    28. Sherman PM, Johnson-Henry KC, Yeung HP, Ngo PS, Goulet J, Tompkins TA. Probiotics reduce enterohemorrhagic Escherichia coli O157:H7- and enteropathogenic E. coli O127:H6-induced changes in polarized T84 epithelial cell monolayers by reducing bacterial adhesion and cytoskeletal rearrangements. Infect Immun. 2005 Aug; 73(8):5183-8. PMID: 16041036; PMCID: PMC1201237.
      View in: PubMed, PubMed Central
    29. Johnson-Henry KC, Nadjafi M, Avitzur Y, Mitchell DJ, Ngan BY, Galindo-Mata E, Jones NL, Sherman PM. Amelioration of the effects of Citrobacter rodentium infection in mice by pretreatment with probiotics. J Infect Dis. 2005 Jun 15; 191(12):2106-17. PMID: 15897997.
      View in: PubMed
    30. Kathene C. Johnson-Henry, Jason D. Riff, Mahsa Gordanpour, Philip M. Sherman. Probiotics in GI Bacterial Infections. Nutrafoods. 2005; 2/3(4):29-36.
    31. Johnson-Henry KC, Mitchell DJ, Avitzur Y, Galindo-Mata E, Jones NL, Sherman PM. Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice. Dig Dis Sci. 2004 Aug; 49(7-8):1095-102. PMID: 15387328.
      View in: PubMed
    32. Mooney A, Byrne C, Clyne M, Johnson-Henry K, Sherman P, Bourke B. Invasion of human epithelial cells by Campylobacter upsaliensis. Cell Microbiol. 2003 Nov; 5(11):835-47. PMID: 14531898.
      View in: PubMed
    33. Johnson-Henry K, Wallace JL, Basappa NS, Soni R, Wu GK, Sherman PM. Inhibition of attaching and effacing lesion formation following enteropathogenic Escherichia coli and Shiga toxin-producing E. coli infection. Infect Immun. 2001 Nov; 69(11):7152-8. PMID: 11598092; PMCID: PMC100109.
      View in: PubMed, PubMed Central
    34. Roberts EA, Johnson KC, Dippold WG. Ah receptor mediating induction of cytochrome P450IA1 in a novel continuous human liver cell line (Mz-Hep-1). Detection by binding with [3H]2,3,7,8-tetrachlorodibenzo-p-dioxin and relationship to the activity of aryl hydrocarbon hydroxylase. Biochem Pharmacol. 1991 Jul 15; 42(3):521-8. PMID: 1650214.
      View in: PubMed
    35. Roberts EA, Johnson KC, Harper PA, Okey AB. Characterization of the Ah receptor mediating aryl hydrocarbon hydroxylase induction in the human liver cell line Hep G2. Arch Biochem Biophys. 1990 Feb 01; 276(2):442-50. PMID: 2154949.
      View in: PubMed
    36. Lang AE, Johnson K. Akathisia in idiopathic Parkinson's disease. Neurology. 1987 Mar; 37(3):477-81. PMID: 3822142.
      View in: PubMed
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