 RNA, Messenger
"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
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| MeSH Number(s) |
D13.444.735.544
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| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Polyadenylated mRNA
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Poly(A)+ mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 1 | 2 | | 1984 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 1 | 1 | 2 | | 1988 | 3 | 5 | 8 | | 1989 | 1 | 2 | 3 | | 1990 | 3 | 7 | 10 | | 1991 | 0 | 9 | 9 | | 1992 | 1 | 14 | 15 | | 1993 | 3 | 11 | 14 | | 1994 | 4 | 19 | 23 | | 1995 | 2 | 19 | 21 | | 1996 | 3 | 21 | 24 | | 1997 | 1 | 13 | 14 | | 1998 | 3 | 17 | 20 | | 1999 | 1 | 10 | 11 | | 2000 | 3 | 27 | 30 | | 2001 | 1 | 17 | 18 | | 2002 | 2 | 18 | 20 | | 2003 | 2 | 26 | 28 | | 2004 | 1 | 22 | 23 | | 2005 | 2 | 35 | 37 | | 2006 | 0 | 20 | 20 | | 2007 | 1 | 15 | 16 | | 2008 | 0 | 14 | 14 | | 2009 | 0 | 19 | 19 | | 2010 | 1 | 10 | 11 | | 2011 | 6 | 13 | 19 | | 2012 | 3 | 23 | 26 | | 2013 | 2 | 12 | 14 | | 2014 | 4 | 13 | 17 | | 2015 | 3 | 11 | 14 | | 2016 | 2 | 11 | 13 | | 2017 | 3 | 12 | 15 | | 2018 | 2 | 12 | 14 | | 2019 | 4 | 3 | 7 | | 2020 | 0 | 6 | 6 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Achiha T, Kijima N, Kodama Y, Kagawa N, Kinoshita M, Fujimoto Y, Nonaka M, Fukai J, Inoue A, Nishida N, Yamanaka T, Harada A, Mori K, Tsuyuguchi N, Uda T, Ishibashi K, Tomogane Y, Sakamoto D, Shofuda T, Yoshioka E, Kanematsu D, Mano M, Luu B, Taylor MD, Kanemura Y, Kishima H. Activated leukocyte cell adhesion molecule expression correlates with the WNT subgroup in medulloblastoma and is involved in regulating tumor cell proliferation and invasion. PLoS One. 2020; 15(12):e0243272.
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Wu Q, Ba-Alawi W, Deblois G, Cruickshank J, Duan S, Lima-Fernandes E, Haight J, Tonekaboni SAM, Fortier AM, Kuasne H, McKee TD, Mahmoud H, Kushida M, Cameron S, Dogan-Artun N, Chen W, Nie Y, Zhang LX, Vellanki RN, Zhou S, Prinos P, Wouters BG, Dirks PB, Done SJ, Park M, Cescon DW, Haibe-Kains B, Lupien M, Arrowsmith CH. GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer. Nat Commun. 2020 08 21; 11(1):4205.
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Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G. Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nat Commun. 2020 04 24; 11(1):2018.
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Koneru B, Lopez G, Farooqi A, Conkrite KL, Nguyen TH, Macha SJ, Modi A, Rokita JL, Urias E, Hindle A, Davidson H, Mccoy K, Nance J, Yazdani V, Irwin MS, Yang S, Wheeler DA, Maris JM, Diskin SJ, Reynolds CP. Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma. Cancer Res. 2020 06 15; 80(12):2663-2675.
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Abrahamson JR, Read A, Chin K, Mistry N, Joo H, Desjardins JF, Liu E, Thai K, Wilson DF, Vinogradov SA, Maynes JT, Gilbert RE, Connelly KA, Baker AJ, Mazer CD, Hare GMT. Renal tissue Po2 sensing during acute hemodilution is dependent on the diluent. . 2020 04 01; 318(4):R799-R812.
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Lamhonwah AM, Tein I. Expression of the organic cation/carnitine transporter family (Octn1,-2 and-3) in mdx muscle and heart: Implications for early carnitine therapy in Duchenne muscular dystrophy to improve cellular carnitine homeostasis. Clin Chim Acta. 2020 Jun; 505:92-97.
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Youn JY, Dyakov BJA, Zhang J, Knight JDR, Vernon RM, Forman-Kay JD, Gingras AC. Properties of Stress Granule and P-Body Proteomes. Mol Cell. 2019 10 17; 76(2):286-294.
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Darby JRT, Saini BS, Soo JY, Lock MC, Holman SL, Bradshaw EL, McInnes SJP, Voelcker NH, Macgowan CK, Seed M, Wiese MD, Morrison JL. Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth. J Physiol. 2019 10; 597(20):5063-5077.
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Narula A, Ellis J, Taliaferro JM, Rissland OS. Coding regions affect mRNA stability in human cells. RNA. 2019 12; 25(12):1751-1764.
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Kim TH, Tsang B, Vernon RM, Sonenberg N, Kay LE, Forman-Kay JD. Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation. Science. 2019 08 23; 365(6455):825-829.
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