Loading...
Reach Banner
Keywords
Last name
Institution

Sterol 14-Demethylase

"Sterol 14-Demethylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.


expand / collapse publications
This graph shows the total number of publications written about "Sterol 14-Demethylase" by people in this website by year, and whether "Sterol 14-Demethylase" was a major or minor topic of these publications.
Bar chart showing 2 publications over 2 distinct years, with a maximum of 1 publications in 1996 and 1999
To see the data from this visualization as text, click here.
People Expand Description
_
Similar Concepts expand description
_
Top Journals expand description