Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Descriptor ID |
D016207
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MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1991 | 0 | 2 | 2 | 1993 | 2 | 0 | 2 | 1994 | 2 | 4 | 6 | 1995 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 1999 | 0 | 2 | 2 | 2000 | 0 | 3 | 3 | 2001 | 0 | 2 | 2 | 2002 | 1 | 2 | 3 | 2003 | 2 | 1 | 3 | 2004 | 3 | 2 | 5 | 2005 | 2 | 1 | 3 | 2006 | 4 | 9 | 13 | 2007 | 3 | 3 | 6 | 2008 | 2 | 6 | 8 | 2009 | 2 | 7 | 9 | 2010 | 3 | 11 | 14 | 2011 | 1 | 6 | 7 | 2012 | 3 | 9 | 12 | 2013 | 4 | 4 | 8 | 2014 | 4 | 2 | 6 | 2015 | 2 | 4 | 6 | 2016 | 1 | 7 | 8 | 2017 | 0 | 5 | 5 | 2018 | 1 | 4 | 5 | 2019 | 1 | 5 | 6 | 2020 | 1 | 6 | 7 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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López-Haber C, Levin-Konigsberg R, Zhu Y, Bi-Karchin J, Balla T, Grinstein S, Marks MS, Mantegazza AR. Phosphatidylinositol-4-kinase IIa licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28251-28262.
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De Boeck A, Ahn BY, D'Mello C, Lun X, Menon SV, Alshehri MM, Szulzewsky F, Shen Y, Khan L, Dang NH, Reichardt E, Goring KA, King J, Grisdale CJ, Grinshtein N, Hambardzumyan D, Reilly KM, Blough MD, Cairncross JG, Yong VW, Marra MA, Jones SJM, Kaplan DR, McCoy KD, Holland EC, Bose P, Chan JA, Robbins SM, Senger DL. Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression. Nat Commun. 2020 10 05; 11(1):4997.
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Bohn MK, Hall A, Sepiashvili L, Jung B, Steele S, Adeli K. Pathophysiology of COVID-19: Mechanisms Underlying Disease Severity and Progression. Physiology (Bethesda). 2020 09 01; 35(5):288-301.
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Bindoli S, Felicetti M, Sfriso P, Doria A. The amount of cytokine-release defines different shades of Sars-Cov2 infection. Exp Biol Med (Maywood). 2020 06; 245(11):970-976.
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Schultz KR, Kariminia A, Ng B, Abdossamadi S, Lauener M, Nemecek ER, Wahlstrom JT, Kitko CL, Lewis VA, Schechter T, Jacobsohn DA, Harris AC, Pulsipher MA, Bittencourt H, Choi SW, Caywood EH, Kasow KA, Bhatia M, Oshrine BR, Flower A, Chaudhury S, Coulter D, Chewning JH, Joyce M, Savasan S, Pawlowska AB, Megason GC, Mitchell D, Cheerva AC, Lawitschka A, Azadpour S, Ostroumov E, Subrt P, Halevy A, Mostafavi S, Cuvelier GDE. Immune profile differences between chronic GVHD and late acute GVHD: results of the ABLE/PBMTC 1202 studies. Blood. 2020 04 09; 135(15):1287-1298.
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Mao S, Ouyang W, Zhou Y, Zeng R, Zhao X, Chen Q, Zhang M, Hinek A. Addition of Chinese herbal remedy, Tongguan Capsules, to the standard treatment in patients with myocardial infarction improve the ventricular reperfusion and remodeling: Proteomic analysis of possible signaling pathways. J Ethnopharmacol. 2020 Jul 15; 257:112794.
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Alganabi M, Zhu H, O'Connell JS, Biouss G, Zito A, Li B, Bindi E, Pierro A. Calcium/calmodulin-dependent protein kinase IV signaling pathway is upregulated in experimental necrotizing enterocolitis. Pediatr Surg Int. 2020 Mar; 36(3):271-277.
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Van JAD, Clotet-Freixas S, Zhou J, Batruch I, Sun C, Glogauer M, Rampoldi L, Elia Y, Mahmud FH, Sochett E, Diamandis EP, Scholey JW, Konvalinka A. Peptidomic Analysis of Urine from Youths with Early Type 1 Diabetes Reveals Novel Bioactivity of Uromodulin Peptides In Vitro. Mol Cell Proteomics. 2020 03; 19(3):501-517.
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Hafiz W, Nori R, Bregasi A, Noamani B, Bonilla D, Lisnevskaia L, Silverman E, Bookman AAM, Johnson SR, Landolt-Marticorena C, Wither J. Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease. Arthritis Res Ther. 2019 11 04; 21(1):223.
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Lee C, Lau E, Chusilp S, Filler R, Li B, Zhu H, Yamoto M, Pierro A. Protective effects of vitamin D against injury in intestinal epithelium. Pediatr Surg Int. 2019 Dec; 35(12):1395-1401.
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