 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.087.680 G02.149.115.680 G03.495.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1981 | 0 | 2 | 2 | | 1982 | 0 | 4 | 4 | | 1984 | 0 | 3 | 3 | | 1985 | 0 | 2 | 2 | | 1986 | 0 | 2 | 2 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 2 | 2 | | 1993 | 0 | 6 | 6 | | 1994 | 0 | 3 | 3 | | 1995 | 0 | 8 | 8 | | 1996 | 0 | 6 | 6 | | 1997 | 0 | 9 | 9 | | 1998 | 0 | 11 | 11 | | 1999 | 1 | 13 | 14 | | 2000 | 0 | 15 | 15 | | 2001 | 0 | 16 | 16 | | 2002 | 0 | 23 | 23 | | 2003 | 0 | 22 | 22 | | 2004 | 0 | 21 | 21 | | 2005 | 0 | 18 | 18 | | 2006 | 0 | 20 | 20 | | 2007 | 0 | 15 | 15 | | 2008 | 0 | 15 | 15 | | 2009 | 0 | 24 | 24 | | 2010 | 0 | 14 | 14 | | 2011 | 0 | 25 | 25 | | 2012 | 0 | 23 | 23 | | 2013 | 0 | 24 | 24 | | 2014 | 0 | 23 | 23 | | 2015 | 0 | 11 | 11 | | 2016 | 0 | 13 | 13 | | 2017 | 0 | 21 | 21 | | 2018 | 0 | 11 | 11 | | 2019 | 1 | 7 | 8 | | 2020 | 0 | 6 | 6 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Rujas E, Cui H, Sicard T, Semesi A, Julien JP. Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies. Nat Commun. 2020 10 08; 11(1):5066.
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Conicella AE, Huang R, Ripstein ZA, Nguyen A, Wang E, Löhr T, Schuck P, Vendruscolo M, Rubinstein JL, Kay LE. An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase. Proc Natl Acad Sci U S A. 2020 10 20; 117(42):26226-26236.
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Dawson JE, Bah A, Zhang Z, Vernon RM, Lin H, Chong PA, Vanama M, Sonenberg N, Gradinaru CC, Forman-Kay JD. Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition. Nat Commun. 2020 06 19; 11(1):3146.
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Griffiths CD, Bilawchuk LM, McDonough JE, Jamieson KC, Elawar F, Cen Y, Duan W, Lin C, Song H, Casanova JL, Ogg S, Jensen LD, Thienpont B, Kumar A, Hobman TC, Proud D, Moraes TJ, Marchant DJ. IGF1R is an entry receptor for respiratory syncytial virus. Nature. 2020 07; 583(7817):615-619.
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Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X. Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth. J Exp Med. 2020 05 04; 217(5).
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Lim S, Khoo R, Peh KM, Teo J, Chang SC, Ng S, Beilhartz GL, Melnyk RA, Johannes CW, Brown CJ, Lane DP, Henry B, Partridge AW. bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA). Proc Natl Acad Sci U S A. 2020 03 17; 117(11):5791-5800.
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Piñas GE, Parkinson JS. Identification of a Kinase-Active CheA Conformation in Escherichia coli Chemoreceptor Signaling Complexes. J Bacteriol. 2019 12 01; 201(23).
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Li Z, Tomlinson AC, Wong AH, Zhou D, Desforges M, Talbot PJ, Benlekbir S, Rubinstein JL, Rini JM. The human coronavirus HCoV-229E S-protein structure and receptor binding. Elife. 2019 10 25; 8.
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Mitchell CJ, Stone TA, Deber CM. Peptide-Based Efflux Pump Inhibitors of the Small Multidrug Resistance Protein from Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019 09; 63(9).
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Swystun LL, Ogiwara K, Rawley O, Brown C, Georgescu I, Hopman W, Labarque V, Male C, Thom K, Blanchette VS, Carcao MD, Lillicrap D. Genetic determinants of VWF clearance and FVIII binding modify FVIII pharmacokinetics in pediatric hemophilia A patients. Blood. 2019 09 12; 134(11):880-891.
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