 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.087.680 G02.149.115.680 G03.495.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1981 | 0 | 2 | 2 | | 1982 | 0 | 4 | 4 | | 1984 | 0 | 3 | 3 | | 1985 | 0 | 2 | 2 | | 1986 | 0 | 2 | 2 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 2 | 2 | | 1993 | 0 | 6 | 6 | | 1994 | 0 | 3 | 3 | | 1995 | 0 | 8 | 8 | | 1996 | 0 | 6 | 6 | | 1997 | 0 | 9 | 9 | | 1998 | 0 | 11 | 11 | | 1999 | 1 | 13 | 14 | | 2000 | 0 | 15 | 15 | | 2001 | 0 | 16 | 16 | | 2002 | 0 | 23 | 23 | | 2003 | 0 | 22 | 22 | | 2004 | 0 | 21 | 21 | | 2005 | 0 | 18 | 18 | | 2006 | 0 | 20 | 20 | | 2007 | 0 | 15 | 15 | | 2008 | 0 | 15 | 15 | | 2009 | 0 | 24 | 24 | | 2010 | 0 | 14 | 14 | | 2011 | 0 | 25 | 25 | | 2012 | 0 | 23 | 23 | | 2013 | 0 | 24 | 24 | | 2014 | 0 | 23 | 23 | | 2015 | 0 | 11 | 11 | | 2016 | 0 | 13 | 13 | | 2017 | 0 | 21 | 21 | | 2018 | 0 | 11 | 11 | | 2019 | 1 | 7 | 8 | | 2020 | 0 | 13 | 13 | | 2021 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Saric A, Freeman SA, Williamson CD, Jarnik M, Guardia CM, Fernandopulle MS, Gershlick DC, Bonifacino JS. SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum. Nat Commun. 2021 07 27; 12(1):4552.
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Piette BL, Alerasool N, Lin ZY, Lacoste J, Lam MHY, Qian WW, Tran S, Larsen B, Campos E, Peng J, Gingras AC, Taipale M. Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains. Mol Cell. 2021 06 17; 81(12):2549-2565.e8.
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Toyama Y, Harkness RW, Lee TYT, Maynes JT, Kay LE. Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR. Proc Natl Acad Sci U S A. 2021 03 16; 118(11).
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Wybenga-Groot LE, Tench AJ, Simpson CD, Germain JS, Raught B, Moran MF, McGlade CJ. SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function. J Mol Biol. 2021 04 16; 433(8):166880.
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Kucharska I, Thai E, Srivastava A, Rubinstein JL, Pomès R, Julien JP. Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11. Elife. 2020 11 30; 9.
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Dhingani N, Guo C, Pan J, Li Q, Warner N, Jardine S, Leung G, Kotlarz D, Gonzaga-Jauregui C, Klein C, Snapper SB, Navas-López VM, Muise AM. The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease. Sci Rep. 2020 10 29; 10(1):18648.
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Rujas E, Cui H, Sicard T, Semesi A, Julien JP. Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies. Nat Commun. 2020 10 08; 11(1):5066.
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Conicella AE, Huang R, Ripstein ZA, Nguyen A, Wang E, Löhr T, Schuck P, Vendruscolo M, Rubinstein JL, Kay LE. An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase. Proc Natl Acad Sci U S A. 2020 10 20; 117(42):26226-26236.
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Lee H, Beilhartz GL, Kucharska I, Raman S, Cui H, Lam MHY, Liang H, Rubinstein JL, Schramek D, Julien JP, Melnyk RA, Taipale M. Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins. Cell. 2020 07 23; 182(2):345-356.e16.
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Cao WX, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, Ihling C, Pekovic F, Low TCH, Siddiqui NU, Cheng MHK, Angers S, Smibert CA, Wühr M, Wahle E, Lipshitz HD. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Rep. 2020 06 23; 31(12):107783.
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