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Spastic Paraplegia, Hereditary

"Spastic Paraplegia, Hereditary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)


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This graph shows the total number of publications written about "Spastic Paraplegia, Hereditary" by people in this website by year, and whether "Spastic Paraplegia, Hereditary" was a major or minor topic of these publications.
Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2016 and 2017 and 2018
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