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Michael Salter

TitleChief of Research
InstitutionThe Hospital for Sick Children
DepartmentResearch Operations
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
ORCID ORCID Icon0000-0001-6897-6585 Additional info
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    Collapse Biography 
    Collapse education and training
    McGill University, Montreal, CanadaPh. D. (Dean's Honour List)1987Dept. of Physiology
    The University of Western Ontario, London, CanadaM. D.1982Medicine
    Collapse awards and honors
    2015Northbridge Chair in Paediatric Research, The Hospital for Sick Children
    2011 - 2016Anne and Max Tanenbaum Chair in Molecular Medicine , The Hospital for Sick Children
    2004 - 2016Canada Research Chair in Neuroplasticity and Pain (Tier I), The Hospital for Sick Children
    2014 - 2014James E. Beall II Memorial Lectureship, Univ. Texas Medical Branch
    2014 - 2014Dr. Jean Hugill Lectureship, University of Alberta
    2012 - 2012Excellence in Basic Science Research Award, The University of Western Ontario
    2012 - 2012Genome Advance of the Month, National Human Genome Res. Institute
    2011 - 2011Investigator Award , Association for Neurons and Disease
    2007 - 2012International Research Scholar , Howard Hughes Medical Institute
    2009 - 2011Pfizer Neuropathic Pain Research Award, Pfizer
    2006 - 2006Distinguished Career Investigator Award , Canadian Pain Society
    2005Fellow, Royal Society of Canada
    1998 - 2003Investigator, Canadian Institutes of Health Research
    1995 - 1995Early Career Investigator Award , Canadian Pain Society
    1992 - 1997Scholar, Medical Research Council of Canada
    1989 - 1990Centennial Fellowship , Medical Research Council of Canada
    1988 - 1989The John Charles Polanyi Prize in Physiology or Medicine, Province of Ontario
    1988 - 1989Medical Research Council of Canada Fellowship , Medical Research Council of Canada
    1987 - 1988The E.B. Eastburn Fellowship in Advanced Science
    1982 - 1987Medical Research Council of Canada Fellowship, Medical Research Council of Canada
    1982 - 1983Alma Mater Fellowship, McGill University
    1980Elected member, Alpha Omega Alpha Medical Honor Society

    Collapse Overview 
    Collapse overview
    Dr. Salter is Chief of Research at The Hospital for Sick Children (SickKids), a Senior Scientist in the Program in Neurosciences & Mental Health, and a Professor of Physiology at the University of Toronto.

    Dr. Salter received an MD degree from the University of Western Ontario in 1982 and went on to obtain a Ph.D. in Physiology from McGill in 1987. After post-doctoral training at Toronto Western and at Mt. Sinai hospitals, he joined the Research Institute of SickKids in 1990. From 1999 to 2009 Dr. Salter was the founding Director of the University of Toronto Centre for the Study of Pain. Dr. Salter’s main research focus is on synaptic physiology, in particular in relation to pain, and he has done groundbreaking work that has led to new paradigms about neuroplasticity and about how synaptic transmission in the central nervous system is regulated by biochemical processes within neurons and by glial-neuronal interactions. His discoveries have broad implications for the control of cell-cell communication throughout the nervous system and his work has regularly appeared in elite journals including Nature, Science, Cell, Nature Medicine and Neuron. Dr. Salter has a broad interest in neuroscience and his work relevant to learning and memory, stroke-induced neuron death, epilepsy and schizophrenia. As a distinct line of research, he and his collaborators reported in Cell in 2006 their discovery of a previously unsuspected role for sensory neurons in the pathogenesis of diabetes and in the control of glucose homeostasis.

    To facilitate the translation of his fundamental studies to the development of new therapies for humans, Dr. Salter is a founding scientist and actively involved in two startup biotech companies – NoNO Inc and Afference Therapeutics. Dr. Salter currently holds the Northbridge Chair in Paediatric Research. He has received numerous awards including the E.B. Eastburn Award, the John Charles Polyani Prize in Physiology or Medicine, the Early Career Investigator Award of the Canadian Pain Society, the Distinguished Career Investigator Award of the Canadian Pain Society, and was an International Research Scholar of the Howard Hughes Medical Institute. He is a Fellow of the Royal Society of Canada.


    Collapse Research 
    Collapse research activities and funding
         (Michael W. Salter)
    Centre for Developmental Brain Plasticity & Repair (CDBPR)
    Canadian Foundation for Innovation
    Role: Lead PI

         (Michael W. Salter)
    The Krembil Foundation
    Defining new horizons in neuropathic pain
    Role: Sole PI

         (Peter Dirks, Sam Weiss)
    Canada Cancer Stem Cell Dream Team, Stand Up To Cancer
    Targeting brain tumor stem cell epigenetic and molecular networks
    Role: Co-applicant

         (Michael W. Salter)
    Canadian Foundation for Innovation
    Dynamic complexes and large-scale assemblies in neurobiology and disease
    Role: Co-PI

         (Norm Buckley)
    Canadian Institutes of Health Research, SPOR
    Chronic Pain Network
    Role: Co-Investigator

    FDN-154336     (Michael W. Salter)
    CIHR
    Targeting neuronal and glial signaling in chronic pain
    Role: Sole PI

    5R01MH075916-06     (HAHN, CHANG-GYU)Dec 1, 2005 - Jan 31, 2020
    NIH
    Src mediates molecular alterations leading to NMDAR hypofunction in schizophrenia
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Mapplebeck JCS, Dalgarno R, Tu Y, Moriarty O, Beggs S, Kwok CHT, Halievski K, Assi S, Mogil JS, Trang T, Salter MW. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain. 2018 Sep; 159(9):1752-1763. PMID: 29927790.
      View in: PubMed
    2. Wang W, Duclot F, Groveman BR, Carrier N, Qiao H, Fang XQ, Wang H, Xin W, Jiang XH, Salter MW, Ding XS, Kabbaj M, Yu XM. Hippocampal protein kinase D1 is necessary for DHPG-induced learning and memory impairments in rats. PLoS One. 2018; 13(4):e0195095. PMID: 29614089.
      View in: PubMed
    3. Jevtic S, Sengar AS, Salter MW, McLaurin J. The role of the immune system in Alzheimer disease: Etiology and treatment. Ageing Res Rev. 2017 Nov; 40:84-94. PMID: 28941639.
      View in: PubMed
    4. Salter MW, Stevens B. Microglia emerge as central players in brain disease. Nat Med. 2017 Sep 08; 23(9):1018-1027. PMID: 28886007.
      View in: PubMed
    5. Fernandes DJ, Ellegood J, Askalan R, Blakely RD, Dicicco-Bloom E, Egan SE, Osborne LR, Powell CM, Raznahan A, Robins DM, Salter MW, Sengar AS, Veenstra-VanderWeele J, Henkelman RM, Lerch JP. Spatial gene expression analysis of neuroanatomical differences in mouse models. Neuroimage. 2017 12; 163:220-230. PMID: 28882630.
      View in: PubMed
    6. Wyeth MS, Pelkey KA, Yuan X, Vargish G, Johnston AD, Hunt S, Fang C, Abebe D, Mahadevan V, Fisahn A, Salter MW, McInnes RR, Chittajallu R, McBain CJ. Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition. Cell Rep. 2017 Aug 29; 20(9):2156-2168. PMID: 28854365.
      View in: PubMed
    7. Harding EK, Salter MW. VIP cortical conductors set the tone for chronic pain. Nat Neurosci. 2017 Jul 26; 20(8):1037-1038. PMID: 28745719.
      View in: PubMed
    8. Scanlon DP, Bah A, Krzeminski M, Zhang W, Leduc-Pessah HL, Dong YN, Forman-Kay JD, Salter MW. An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors. Nat Commun. 2017 05 16; 8:15220. PMID: 28508887.
      View in: PubMed
    9. Mapplebeck JC, Beggs S, Salter MW. Molecules in pain and sex: a developing story. Mol Brain. 2017 03 07; 10(1):9. PMID: 28270169.
      View in: PubMed
    10. Chan KL, Tam TH, Boroumand P, Prescott D, Costford SR, Escalante NK, Fine N, Tu Y, Robertson SJ, Prabaharan D, Liu Z, Bilan PJ, Salter MW, Glogauer M, Girardin SE, Philpott DJ, Klip A. Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance. Cell Rep. 2017 03 07; 18(10):2415-2426. PMID: 28273456.
      View in: PubMed
    11. Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Rep. 2016 12 06; 17(10):2753-2765. PMID: 27926876.
      View in: PubMed
    12. Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, Masuda T, Kohro Y, Matsunaga N, Tsuda M, Salter MW, Inoue K, Ohdo S. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016 10 14; 7:13102. PMID: 27739425.
      View in: PubMed
    13. Joshi K, Shen L, Michaeli A, Salter M, Thibault-Messier G, Hashmi S, Eubanks JH, Cortez MA, Snead OC. Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel. Ann Neurol. 2016 10; 80(4):511-21. PMID: 27462820.
      View in: PubMed
    14. Masuda T, Ozono Y, Mikuriya S, Kohro Y, Tozaki-Saitoh H, Iwatsuki K, Uneyama H, Ichikawa R, Salter MW, Tsuda M, Inoue K. Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain. Nat Commun. 2016 08 12; 7:12529. PMID: 27515581.
      View in: PubMed
    15. Beggs S, Salter MW. SnapShot: Microglia in Disease. Cell. 2016 May 19; 165(5):1294-1294.e1. PMID: 27203115.
      View in: PubMed
    16. Zhang WB, Ross PJ, Tu Y, Wang Y, Beggs S, Sengar AS, Ellis J, Salter MW. Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons. Sci Rep. 2016 Apr 04; 6:23837. PMID: 27040756; PMCID: PMC4819183.
    17. Mapplebeck JC, Beggs S, Salter MW. Sex differences in pain: a tale of two immune cells. Pain. 2016 Feb; 157 Suppl 1:S2-6. PMID: 26785152.
      View in: PubMed
    18. Khattak S, Brimble E, Zhang W, Zaslavsky K, Strong E, Ross PJ, Hendry J, Mital S, Salter MW, Osborne LR, Ellis J. Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome. Mol Brain. 2015 Nov 24; 8(1):77. PMID: 26603386; PMCID: PMC4657290.
    19. Fang XQ, Qiao H, Groveman BR, Feng S, Pflueger M, Xin WK, Ali MK, Lin SX, Xu J, Duclot F, Kabbaj M, Wang W, Ding XS, Santiago-Sim T, Jiang XH, Salter MW, Yu XM. Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors. Mol Brain. 2015 Nov 19; 8(1):75. PMID: 26584860.
      View in: PubMed
    20. Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM. Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. J Neurosci. 2015 Oct 14; 35(41):13879-88. PMID: 26468188; PMCID: PMC4604226.
    21. Sorge RE, Mapplebeck JC, Rosen S, Beggs S, Taves S, Alexander JK, Martin LJ, Austin JS, Sotocinal SG, Chen D, Yang M, Shi XQ, Huang H, Pillon NJ, Bilan PJ, Tu Y, Klip A, Ji RR, Zhang J, Salter MW, Mogil JS. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat Neurosci. 2015 Aug; 18(8):1081-3. PMID: 26120961; PMCID: PMC4772157.
    22. Djuric U, Cheung AYL, Zhang W, Mok RS, Lai W, Piekna A, Hendry JA, Ross PJ, Pasceri P, Kim DS, Salter MW, Ellis J. MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells. Neurobiol Dis. 2015 Apr; 76:37-45. PMID: 25644311.
      View in: PubMed
    23. Kemp SW, Szynkaruk M, Stanoulis KN, Wood MD, Liu EH, Willand MP, Morlock L, Naidoo J, Williams NS, Ready JM, Mangano TJ, Beggs S, Salter MW, Gordon T, Pieper AA, Borschel GH. Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury. Neuroscience. 2015 Jan 22; 284:202-16. PMID: 25313000.
      View in: PubMed
    24. Cahill LS, Laliberté CL, Liu XJ, Bishop J, Nieman BJ, Mogil JS, Sorge RE, Jones CD, Salter MW, Henkelman RM. Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse. Mol Pain. 2014 Sep 13; 10:60. PMID: 25216623; PMCID: PMC4190293.
    25. Salter MW, Beggs S. Sublime microglia: expanding roles for the guardians of the CNS. Cell. 2014 Jul 03; 158(1):15-24. PMID: 24995975.
      View in: PubMed
    26. Salter MW. Deepening understanding of the neural substrates of chronic pain. Brain. 2014 Mar; 137(Pt 3):651-3. PMID: 24549811.
      View in: PubMed
    27. Hildebrand ME, Pitcher GM, Harding EK, Li H, Beggs S, Salter MW. GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord. Sci Rep. 2014 Feb 13; 4:4094. PMID: 24522697; PMCID: PMC3923208.
    28. Wyeth MS, Pelkey KA, Petralia RS, Salter MW, McInnes RR, McBain CJ. Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses. J Neurosci. 2014 Jan 08; 34(2):622-8. PMID: 24403160; PMCID: PMC3870939.
    29. Bourinet E, Altier C, Hildebrand ME, Trang T, Salter MW, Zamponi GW. Calcium-permeable ion channels in pain signaling. Physiol Rev. 2014 Jan; 94(1):81-140. PMID: 24382884.
      View in: PubMed
    30. Beggs S, Salter MW. The known knowns of microglia-neuronal signalling in neuropathic pain. Neurosci Lett. 2013 Dec 17; 557 Pt A:37-42. PMID: 23994389.
      View in: PubMed
    31. Han L, Campanucci VA, Cooke J, Salter MW. Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors. Mol Brain. 2013 Aug 13; 6:36. PMID: 23941530; PMCID: PMC3846451.
    32. Paltser G, Liu XJ, Yantha J, Winer S, Tsui H, Wu P, Maezawa Y, Cahill LS, Laliberté CL, Ramagopalan SV, DeLuca GC, Sadovnick AD, Astsaturov I, Ebers GC, Henkelman RM, Salter MW, Dosch HM. TRPV1 gates tissue access and sustains pathogenicity in autoimmune encephalitis. Mol Med. 2013 Jul 24; 19:149-59. PMID: 23689362.
      View in: PubMed
    33. Sengar AS, Ellegood J, Yiu AP, Wang H, Wang W, Juneja SC, Lerch JP, Josselyn SA, Henkelman RM, Salter MW, Egan SE. Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition. J Neurosci. 2013 Feb 27; 33(9):4055-65. PMID: 23447614.
      View in: PubMed
    34. Ivakine EA, Acton BA, Mahadevan V, Ormond J, Tang M, Pressey JC, Huang MY, Ng D, Delpire E, Salter MW, Woodin MA, McInnes RR. Neto2 is a KCC2 interacting protein required for neuronal Cl- regulation in hippocampal neurons. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3561-6. PMID: 23401525; PMCID: PMC3587235.
    35. Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl? homeostasis. Nat Neurosci. 2013 Feb; 16(2):183-92. PMID: 23292683; PMCID: PMC4974077.
    36. Tang M, Ivakine E, Mahadevan V, Salter MW, McInnes RR. Neto2 interacts with the scaffolding protein GRIP and regulates synaptic abundance of kainate receptors. PLoS One. 2012; 7(12):e51433. PMID: 23236500; PMCID: PMC3516556.
    37. Olausson P, Venkitaramani DV, Moran TD, Salter MW, Taylor JR, Lombroso PJ. The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity. Neuroscience. 2012 Dec 06; 225:1-8. PMID: 22885232; PMCID: PMC3725644.
    38. Beggs S, Alvares D, Moss A, Currie G, Middleton J, Salter MW, Fitzgerald M. A role for NT-3 in the hyperinnervation of neonatally wounded skin. Pain. 2012 Oct; 153(10):2133-9. PMID: 22871470; PMCID: PMC3657181.
    39. Gagliese L, Katz L, Gibson M, Clark AJ, Lussier D, Gordon A, Salter MW. A brief educational intervention about pain and aging for older members of the community and health care workers. J Pain. 2012 Sep; 13(9):849-56. PMID: 22841472.
      View in: PubMed
    40. Beggs S, Trang T, Salter MW. P2X4R+ microglia drive neuropathic pain. Nat Neurosci. 2012 Jul 26; 15(8):1068-73. PMID: 22837036; PMCID: PMC5023423.
    41. Tsuda M, Beggs S, Salter MW, Inoue K. Microglia and intractable chronic pain. Glia. 2013 Jan; 61(1):55-61. PMID: 22740331.
      View in: PubMed
    42. Trang T, Beggs S, Salter MW. Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain. Neuron Glia Biol. 2011 Feb; 7(1):99-108. PMID: 22613083; PMCID: PMC3748035.
    43. Trang T, Salter MW. P2X4 purinoceptor signaling in chronic pain. Purinergic Signal. 2012 Sep; 8(3):621-8. PMID: 22528681; PMCID: PMC3360095.
    44. Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, Herbert TA, Yarkoni-Abitbul M, Tichauer D, Livneh J, Gershon E, Zheng M, Tan K, John SL, Slade GD, Jordan J, Woolf CJ, Peltz G, Maixner W, Diatchenko L, Seltzer Z, Salter MW, Mogil JS. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med. 2012 Mar 25; 18(4):595-9. PMID: 22447075; PMCID: PMC3350463.
    45. Farra N, Zhang WB, Pasceri P, Eubanks JH, Salter MW, Ellis J. Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations. Mol Psychiatry. 2012 Dec; 17(12):1261-71. PMID: 22230884; PMCID: PMC3504383.
    46. Yang K, Trepanier C, Sidhu B, Xie YF, Li H, Lei G, Salter MW, Orser BA, Nakazawa T, Yamamoto T, Jackson MF, Macdonald JF. Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases. EMBO J. 2012 Feb 15; 31(4):805-16. PMID: 22187052; PMCID: PMC3280552.
    47. Salter MW, Pitcher GM. Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia. FEBS J. 2012 Jan; 279(1):2-11. PMID: 21985289; PMCID: PMC3589551.
    48. Beggs S, Currie G, Salter MW, Fitzgerald M, Walker SM. Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity. Brain. 2012 Feb; 135(Pt 2):404-17. PMID: 22102650; PMCID: PMC3281475.
    49. Trang T, Beggs S, Salter MW. ATP receptors gate microglia signaling in neuropathic pain. Exp Neurol. 2012 Apr; 234(2):354-61. PMID: 22116040; PMCID: PMC3748033.
    50. Sorge RE, LaCroix-Fralish ML, Tuttle AH, Sotocinal SG, Austin JS, Ritchie J, Chanda ML, Graham AC, Topham L, Beggs S, Salter MW, Mogil JS. Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice. J Neurosci. 2011 Oct 26; 31(43):15450-4. PMID: 22031891; PMCID: PMC3218430.
    51. Asrar S, Kaneko K, Takao K, Negandhi J, Matsui M, Shibasaki K, Miyakawa T, Harrison RV, Jia Z, Salter MW, Tominaga M, Fukumi-Tominaga T. DIP/WISH deficiency enhances synaptic function and performance in the Barnes maze. Mol Brain. 2011 Oct 21; 4:39. PMID: 22018352; PMCID: PMC3208581.
    52. Hildebrand ME, Mezeyova J, Smith PL, Salter MW, Tringham E, Snutch TP. Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons. Mol Pain. 2011 Sep 12; 7:67. PMID: 21910862; PMCID: PMC3190347.
    53. Tang M, Pelkey KA, Ng D, Ivakine E, McBain CJ, Salter MW, McInnes RR. Neto1 is an auxiliary subunit of native synaptic kainate receptors. J Neurosci. 2011 Jul 06; 31(27):10009-18. PMID: 21734292.
      View in: PubMed
    54. Pitcher GM, Kalia LV, Ng D, Goodfellow NM, Yee KT, Lambe EK, Salter MW. Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors. Nat Med. 2011 Apr; 17(4):470-8. PMID: 21441918; PMCID: PMC3264662.
    55. Tsuda M, Kohro Y, Yano T, Tsujikawa T, Kitano J, Tozaki-Saitoh H, Koyanagi S, Ohdo S, Ji RR, Salter MW, Inoue K. JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. Brain. 2011 Apr; 134(Pt 4):1127-39. PMID: 21371995.
      View in: PubMed
    56. Kimura T, Kawabe H, Jiang C, Zhang W, Xiang YY, Lu C, Salter MW, Brose N, Lu WY, Rotin D. Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3216-21. PMID: 21300902; PMCID: PMC3044364.
    57. Beggs S, Salter MW. A straightjacket for pain? Cell. 2010 Nov 12; 143(4):505-7. PMID: 21074043.
      View in: PubMed
    58. Beggs S, Liu XJ, Kwan C, Salter MW. Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier. Mol Pain. 2010 Nov 02; 6:74. PMID: 21044346; PMCID: PMC2984489.
    59. Beggs S, Salter MW. Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0. Curr Opin Neurobiol. 2010 Aug; 20(4):474-80. PMID: 20817512; PMCID: PMC3589562.
    60. Liu XJ, Salter MW. Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn. Eur J Neurosci. 2010 Jul; 32(2):278-89. PMID: 20629726; PMCID: PMC3589563.
    61. Li HB, Jackson MF, Yang K, Trepanier C, Salter MW, Orser BA, Macdonald JF. Plasticity of synaptic GluN receptors is required for the Src-dependent induction of long-term potentiation at CA3-CA1 synapses. Hippocampus. 2011 Oct; 21(10):1053-61. PMID: 20865743.
      View in: PubMed
    62. Vargas-Caballero M, Martin LJ, Salter MW, Orser BA, Paulsen O. alpha5 Subunit-containing GABA(A) receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation. Neuropharmacology. 2010 Mar; 58(3):668-75. PMID: 19941877.
      View in: PubMed
    63. Okada-Ogawa A, Suzuki I, Sessle BJ, Chiang CY, Salter MW, Dostrovsky JO, Tsuboi Y, Kondo M, Kitagawa J, Kobayashi A, Noma N, Imamura Y, Iwata K. Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanisms. J Neurosci. 2009 Sep 09; 29(36):11161-71. PMID: 19741123; PMCID: PMC2804401.
    64. Trang T, Beggs S, Wan X, Salter MW. P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation. J Neurosci. 2009 Mar 18; 29(11):3518-28. PMID: 19295157; PMCID: PMC3589565.
    65. Ng D, Pitcher GM, Szilard RK, Sertié A, Kanisek M, Clapcote SJ, Lipina T, Kalia LV, Joo D, McKerlie C, Cortez M, Roder JC, Salter MW, McInnes RR. Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol. 2009 Feb 24; 7(2):e41. PMID: 19243221; PMCID: PMC2652390.
    66. Liu XJ, Gingrich JR, Vargas-Caballero M, Dong YN, Sengar A, Beggs S, Wang SH, Ding HK, Frankland PW, Salter MW. Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nat Med. 2008 Dec; 14(12):1325-32. PMID: 19011637; PMCID: PMC3616027.
    67. Hunter J, Watt-Watson J, McGillion M, Raman-Wilms L, Cockburn L, Lax L, Stinson J, Cameron A, Dao T, Pennefather P, Schreiber M, Librach L, Kavanagh T, Gordon A, Cullen N, Mock D, Salter M. An interfaculty pain curriculum: lessons learned from six years experience. Pain. 2008 Nov 15; 140(1):74-86. PMID: 18774226.
      View in: PubMed
    68. Kalia LV, Kalia SK, Salter MW. NMDA receptors in clinical neurology: excitatory times ahead. Lancet Neurol. 2008 Aug; 7(8):742-55. PMID: 18635022; PMCID: PMC3589564.
    69. Sun HS, Doucette TA, Liu Y, Fang Y, Teves L, Aarts M, Ryan CL, Bernard PB, Lau A, Forder JP, Salter MW, Wang YT, Tasker RA, Tymianski M. Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke. 2008 Sep; 39(9):2544-53. PMID: 18617669.
      View in: PubMed
    70. Beggs S, Salter MW. Taking two cuts at pain. Nat Med. 2008 Mar; 14(3):243-4. PMID: 18323841.
      View in: PubMed
    71. Pitcher GM, Beggs S, Woo RS, Mei L, Salter MW. ErbB4 is a suppressor of long-term potentiation in the adult hippocampus. Neuroreport. 2008 Jan 22; 19(2):139-43. PMID: 18185097; PMCID: PMC3707840.
    72. Keller AF, Beggs S, Salter MW, De Koninck Y. Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain. Mol Pain. 2007 Sep 27; 3:27. PMID: 17900333; PMCID: PMC2093929.
    73. Cui H, Hayashi A, Sun HS, Belmares MP, Cobey C, Phan T, Schweizer J, Salter MW, Wang YT, Tasker RA, Garman D, Rabinowitz J, Lu PS, Tymianski M. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci. 2007 Sep 12; 27(37):9901-15. PMID: 17855605.
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    74. Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, Jia Z, Kaang BK, Kawamata M, Kida S, Klann E, Kohno T, Li M, Li XJ, MacDonald JF, Nader K, Nguyen PV, Oh U, Ren K, Roder JC, Salter MW, Song W, Sugita S, Tang SJ, Tao Y, Wang YT, Woo N, Woodin MA, Yan Z, Yoshimura M, Xu M, Xu ZC, Zhang X, Zhen M, Zhuo M. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Mol Pain. 2006 Dec 30; 2:38. PMID: 17196111; PMCID: PMC1769477.
    75. Beggs S, Salter MW. Stereological and somatotopic analysis of the spinal microglial response to peripheral nerve injury. Brain Behav Immun. 2007 Jul; 21(5):624-33. PMID: 17267172; PMCID: PMC5021535.
    76. Razavi R, Chan Y, Afifiyan FN, Liu XJ, Wan X, Yantha J, Tsui H, Tang L, Tsai S, Santamaria P, Driver JP, Serreze D, Salter MW, Dosch HM. TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell. 2006 Dec 15; 127(6):1123-35. PMID: 17174891.
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    77. Moss A, Beggs S, Vega-Avelaira D, Costigan M, Hathway GJ, Salter MW, Fitzgerald M. Spinal microglia and neuropathic pain in young rats. Pain. 2007 Apr; 128(3):215-24. PMID: 17110040.
      View in: PubMed
    78. Paul S, Olausson P, Venkitaramani DV, Ruchkina I, Moran TD, Tronson N, Mills E, Hakim S, Salter MW, Taylor JR, Lombroso PJ. The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala. Biol Psychiatry. 2007 May 01; 61(9):1049-61. PMID: 17081505; PMCID: PMC1853327.
    79. MacVicar BA, Salter MW. Neuroscience: controlled capillaries. Nature. 2006 Oct 12; 443(7112):642-3. PMID: 17035989.
      View in: PubMed
    80. Kalia LV, Pitcher GM, Pelkey KA, Salter MW. PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex. EMBO J. 2006 Oct 18; 25(20):4971-82. PMID: 16990796; PMCID: PMC1618112.
    81. Trang T, Beggs S, Salter MW. Purinoceptors in microglia and neuropathic pain. Pflugers Arch. 2006 Aug; 452(5):645-52. PMID: 16767466.
      View in: PubMed
    82. Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y. BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature. 2005 Dec 15; 438(7070):1017-21. PMID: 16355225.
      View in: PubMed
    83. Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci. 2005 Aug; 8(8):1051-8. PMID: 16025111.
      View in: PubMed
    84. Chiang CY, Zhang S, Xie YF, Hu JW, Dostrovsky JO, Salter MW, Sessle BJ. Endogenous ATP involvement in mustard-oil-induced central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn). J Neurophysiol. 2005 Sep; 94(3):1751-60. PMID: 15901761.
      View in: PubMed
    85. Taverna FA, Georgiou J, McDonald RJ, Hong NS, Kraev A, Salter MW, Takeshima H, Muller RU, Roder JC. Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation. J Physiol. 2005 Jun 01; 565(Pt 2):579-91. PMID: 15774528; PMCID: PMC1464524.
    86. Tsuda M, Inoue K, Salter MW. Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci. 2005 Feb; 28(2):101-7. PMID: 15667933.
      View in: PubMed
    87. Liu XJ, Salter MW. Purines and pain mechanisms: recent developments. Curr Opin Investig Drugs. 2005 Jan; 6(1):65-75. PMID: 15675605.
      View in: PubMed
    88. Salter MW. Cellular signalling pathways of spinal pain neuroplasticity as targets for analgesic development. Curr Top Med Chem. 2005; 5(6):557-67. PMID: 16022678.
      View in: PubMed
    89. Kalia LV, Gingrich JR, Salter MW. Src in synaptic transmission and plasticity. Oncogene. 2004 Oct 18; 23(48):8007-16. PMID: 15489918.
      View in: PubMed
    90. Wang Y, Ju W, Liu L, Fam S, D'Souza S, Taghibiglou C, Salter M, Wang YT. alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor (AMPAR) endocytosis is essential for N-methyl-D-aspartate-induced neuronal apoptosis. J Biol Chem. 2004 Oct 01; 279(40):41267-70. PMID: 15319422.
      View in: PubMed
    91. Watt-Watson J, Hunter J, Pennefather P, Librach L, Raman-Wilms L, Schreiber M, Lax L, Stinson J, Dao T, Gordon A, Mock D, Salter M. An integrated undergraduate pain curriculum, based on IASP curricula, for six health science faculties. Pain. 2004 Jul; 110(1-2):140-8. PMID: 15275761.
      View in: PubMed
    92. Nong Y, Huang YQ, Salter MW. NMDA receptors are movin' in. Curr Opin Neurobiol. 2004 Jun; 14(3):353-61. PMID: 15194116.
      View in: PubMed
    93. Gingrich JR, Pelkey KA, Fam SR, Huang Y, Petralia RS, Wenthold RJ, Salter MW. Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2. Proc Natl Acad Sci U S A. 2004 Apr 20; 101(16):6237-42. PMID: 15069201; PMCID: PMC395953.
    94. Salter MW, Kalia LV. Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci. 2004 Apr; 5(4):317-28. PMID: 15034556.
      View in: PubMed
    95. Salter MW. Cellular neuroplasticity mechanisms mediating pain persistence. J Orofac Pain. 2004; 18(4):318-24. PMID: 15636015.
      View in: PubMed
    96. Kalia LV, Salter MW. Interactions between Src family protein tyrosine kinases and PSD-95. Neuropharmacology. 2003 Nov; 45(6):720-8. PMID: 14529711.
      View in: PubMed
    97. Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature. 2003 Aug 14; 424(6950):778-83. PMID: 12917686.
      View in: PubMed
    98. Gallagher CJ, Salter MW. Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors. J Neurosci. 2003 Jul 30; 23(17):6728-39. PMID: 12890765.
      View in: PubMed
    99. Fam SR, Gallagher CJ, Kalia LV, Salter MW. Differential frequency dependence of P2Y1- and P2Y2- mediated Ca 2+ signaling in astrocytes. J Neurosci. 2003 Jun 01; 23(11):4437-44. PMID: 12805284.
      View in: PubMed
    100. Salter MW. D1 and NMDA receptors hook up: expanding on an emerging theme. Trends Neurosci. 2003 May; 26(5):235-7. PMID: 12744837.
      View in: PubMed
    101. Ma L, Huang YZ, Pitcher GM, Valtschanoff JG, Ma YH, Feng LY, Lu B, Xiong WC, Salter MW, Weinberg RJ, Mei L. Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts. J Neurosci. 2003 Apr 15; 23(8):3164-75. PMID: 12716924.
      View in: PubMed
    102. Nong Y, Huang YQ, Ju W, Kalia LV, Ahmadian G, Wang YT, Salter MW. Glycine binding primes NMDA receptor internalization. Nature. 2003 Mar 20; 422(6929):302-7. PMID: 12646920.
      View in: PubMed
    103. Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, Wang YT, Salter MW, Tymianski M. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science. 2002 Oct 25; 298(5594):846-50. PMID: 12399596.
      View in: PubMed
    104. Pelkey KA, Askalan R, Paul S, Kalia LV, Nguyen TH, Pitcher GM, Salter MW, Lombroso PJ. Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation. Neuron. 2002 Mar 28; 34(1):127-38. PMID: 11931747.
      View in: PubMed
    105. Cheng HY, Pitcher GM, Laviolette SR, Whishaw IQ, Tong KI, Kockeritz LK, Wada T, Joza NA, Crackower M, Goncalves J, Sarosi I, Woodgett JR, Oliveira-dos-Santos AJ, Ikura M, van der Kooy D, Salter MW, Penninger JM. DREAM is a critical transcriptional repressor for pain modulation. Cell. 2002 Jan 11; 108(1):31-43. PMID: 11792319.
      View in: PubMed
    106. Salter MW. LTP gets culture. Trends Neurosci. 2001 Oct; 24(10):560-1. PMID: 11576651.
      View in: PubMed
    107. Ali DW, Salter MW. NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol. 2001 Jun; 11(3):336-42. PMID: 11399432.
      View in: PubMed
    108. Huang Y, Lu W, Ali DW, Pelkey KA, Pitcher GM, Lu YM, Aoto H, Roder JC, Sasaki T, Salter MW, MacDonald JF. CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron. 2001 Feb; 29(2):485-96. PMID: 11239437.
      View in: PubMed
    109. Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science. 2000 Jun 09; 288(5472):1765-9. PMID: 10846153.
      View in: PubMed
    110. Salter MW, Wang YT. Sodium channels develop a tyrosine phosphatase complex. Nat Neurosci. 2000 May; 3(5):417-9. PMID: 10769374.
      View in: PubMed
    111. Huang YZ, Won S, Ali DW, Wang Q, Tanowitz M, Du QS, Pelkey KA, Yang DJ, Xiong WC, Salter MW, Mei L. Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses. Neuron. 2000 May; 26(2):443-55. PMID: 10839362.
      View in: PubMed
    112. Fam SR, Gallagher CJ, Salter MW. P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes. J Neurosci. 2000 Apr 15; 20(8):2800-8. PMID: 10751431.
      View in: PubMed
    113. Taverna F, Xiong ZG, Brandes L, Roder JC, Salter MW, MacDonald JF. The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. J Biol Chem. 2000 Mar 24; 275(12):8475-9. PMID: 10722683.
      View in: PubMed
    114. Xiong ZG, Pelkey KA, Lu WY, Lu YM, Roder JC, MacDonald JF, Salter MW. Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J Neurosci. 1999 Nov 01; 19(21):RC37. PMID: 10531471.
      View in: PubMed
    115. Yu XM, Salter MW. Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7697-704. PMID: 10393883; PMCID: PMC33604.
    116. Salter MW. A pinch of salt for NMDA receptors. Mol Psychiatry. 1999 May; 4(3):209-11. PMID: 10395205.
      View in: PubMed
    117. Salter MW, De Koninck Y. An ambiguous fast synapse: a new twist in the tale of two transmitters. Nat Neurosci. 1999 Mar; 2(3):199-200. PMID: 10195207.
      View in: PubMed
    118. Gallagher CJ, Salter MW. Nucleotide receptor signalling in spinal cord astrocytes: findings and functional implications. Prog Brain Res. 1999; 120:311-22. PMID: 10551007.
      View in: PubMed
    119. Yu XM, Salter MW. Gain control of NMDA-receptor currents by intracellular sodium. Nature. 1998 Dec 03; 396(6710):469-74. PMID: 9853755.
      View in: PubMed
    120. Idestrup CP, Salter MW. P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase c/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord. Neuroscience. 1998 Oct; 86(3):913-23. PMID: 9692727.
      View in: PubMed
    121. Salter MW. Src, N-methyl-D-aspartate (NMDA) receptors, and synaptic plasticity. Biochem Pharmacol. 1998 Oct 01; 56(7):789-98. PMID: 9774140.
      View in: PubMed
    122. Lu YM, Roder JC, Davidow J, Salter MW. Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science. 1998 Feb 27; 279(5355):1363-7. PMID: 9478899.
      View in: PubMed
    123. Braunton JL, Wong V, Wang W, Salter MW, Roder J, Liu M, Wang YT. Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro. Neuroscience. 1998 Jan; 82(1):161-70. PMID: 9483512.
      View in: PubMed
    124. Wan Q, Man HY, Braunton J, Wang W, Salter MW, Becker L, Wang YT. Modulation of GABAA receptor function by tyrosine phosphorylation of beta subunits. J Neurosci. 1997 Jul 01; 17(13):5062-9. PMID: 9185543.
      View in: PubMed
    125. Yu XM, Askalan R, Keil GJ, Salter MW. NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science. 1997 Jan 31; 275(5300):674-8. PMID: 9005855.
      View in: PubMed
    126. Stevanovic ZS, Salter MW, Whiteside CI. Extracellular chloride regulates mesangial cell calcium response to vasopressor peptides. Am J Physiol. 1996 Jul; 271(1 Pt 2):F21-9. PMID: 8760239.
      View in: PubMed
    127. Wang YT, Yu XM, Salter MW. Ca(2+)-independent reduction of N-methyl-D-aspartate channel activity by protein tyrosine phosphatase. Proc Natl Acad Sci U S A. 1996 Feb 20; 93(4):1721-5. PMID: 8643696; PMCID: PMC40009.
    128. Pickering DS, Taverna FA, Salter MW, Hampson DR. Palmitoylation of the GluR6 kainate receptor. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):12090-4. PMID: 8618850; PMCID: PMC40302.
    129. Ho C, Hicks J, Salter MW. A novel P2-purinoceptor expressed by a subpopulation of astrocytes from the dorsal spinal cord of the rat. Br J Pharmacol. 1995 Dec; 116(7):2909-18. PMID: 8680724; PMCID: PMC1909233.
    130. Salter MW, Hicks JL. ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord. J Neurosci. 1995 Apr; 15(4):2961-71. PMID: 7722640.
      View in: PubMed
    131. Salter M, Duffy C, Hazelwood R. Determination of brain nitric oxide synthase inhibition in vivo: ex vivo assays of nitric oxide synthase can give incorrect results. Neuropharmacology. 1995 Mar; 34(3):327-34. PMID: 7543191.
      View in: PubMed
    132. Hodaie M, Jeevaratnam P, Salter MW, Roach A. Regulation of intracellular calcium and preprotachykinin neurotransmitter precursor gene expression by patterned electrical stimulation in rat sympathetic neurons. Neurosci Lett. 1995 Feb 13; 185(3):195-8. PMID: 7753490.
      View in: PubMed
    133. De Koninck Y, Salter MW, Henry JL. Substance P released endogenously by high-intensity sensory stimulation potentiates purinergic inhibition of nociceptive dorsal horn neurons induced by peripheral vibration. Neurosci Lett. 1994 Jul 18; 176(1):128-32. PMID: 7526299.
      View in: PubMed
    134. Wang YT, Salter MW. Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature. 1994 May 19; 369(6477):233-5. PMID: 7514272.
      View in: PubMed
    135. Salter MW, Hicks JL. ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord. J Neurosci. 1994 Mar; 14(3 Pt 2):1563-75. PMID: 8126555.
      View in: PubMed
    136. Salter MW, De Koninck Y, Henry JL. Physiological roles for adenosine and ATP in synaptic transmission in the spinal dorsal horn. Prog Neurobiol. 1993 Aug; 41(2):125-56. PMID: 8392739.
      View in: PubMed
    137. Wang YT, Pak YS, Salter MW. Rundown of NMDA-receptor mediated currents is resistant to lowering intracellular [Ca2+] and is prevented by ATP in rat spinal dorsal horn neurons. Neurosci Lett. 1993 Jul 23; 157(2):183-6. PMID: 8233050.
      View in: PubMed
    138. Pickering DS, Thomsen C, Suzdak PD, Fletcher EJ, Robitaille R, Salter MW, MacDonald JF, Huang XP, Hampson DR. A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover. J Neurochem. 1993 Jul; 61(1):85-92. PMID: 8390570.
      View in: PubMed
    139. McPhail ME, Knowles RG, Salter M, Dawson J, Burchell B, Pogson CI. Uptake of acetaminophen (paracetamol) by isolated rat liver cells. Biochem Pharmacol. 1993 Apr 22; 45(8):1599-604. PMID: 8484800.
      View in: PubMed
    140. Salter MW, De Koninck Y, Henry JL. ATP-sensitive K+ channels mediate an IPSP in dorsal horn neurones elicited by sensory stimulation. Synapse. 1992 Jul; 11(3):214-20. PMID: 1636151.
      View in: PubMed
    141. Mody I, Heinemann U, MacDonald JF, Salter MW. Recruitment of NMDA receptors into synaptic transmission after kindling-induced epilepsy and its possible mechanism. Epilepsy Res Suppl. 1992; 8:307-10; discussion 310-1. PMID: 1329821.
      View in: PubMed
    142. Salter M, Knowles RG, Moncada S. Widespread tissue distribution, species distribution and changes in activity of Ca(2+)-dependent and Ca(2+)-independent nitric oxide synthases. FEBS Lett. 1991 Oct 07; 291(1):145-9. PMID: 1718778.
      View in: PubMed
    143. Wang LY, Salter MW, MacDonald JF. Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science. 1991 Sep 06; 253(5024):1132-5. PMID: 1653455.
      View in: PubMed
    144. Salter MW, Henry JL. Responses of functionally identified neurones in the dorsal horn of the cat spinal cord to substance P, neurokinin A and physalaemin. Neuroscience. 1991; 43(2-3):601-10. PMID: 1717888.
      View in: PubMed
    145. MacDonald JF, Bartlett MC, Mody I, Pahapill P, Reynolds JN, Salter MW, Schneiderman JH, Pennefather PS. Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones. J Physiol. 1991 Jan; 432:483-508. PMID: 1832184; PMCID: PMC1181337.
    146. MacDonald JF, Brandes L, Deverill M, Mody I, Salter MW, Theriault E. Mammalian neurons in dissociated cultures form clusters in the presence of retinal pigment epithelium. Exp Brain Res. 1991; 83(3):643-55. PMID: 2026204.
      View in: PubMed
    147. Mody I, Reynolds JN, Salter MW, Carlen PL, MacDonald JF. Kindling-induced epilepsy alters calcium currents in granule cells of rat hippocampal slices. Brain Res. 1990 Oct 29; 531(1-2):88-94. PMID: 1963106.
      View in: PubMed
    148. Salter MW, Henry JL. Differential responses of nociceptive vs. non-nociceptive spinal dorsal horn neurones to cutaneously applied vibration in the cat. Pain. 1990 Mar; 40(3):311-22. PMID: 2326096.
      View in: PubMed
    149. Salter MW, Henry JL. Physiological characteristics of responses of wide dynamic range spinal neurones to cutaneously applied vibration in the cat. Brain Res. 1990 Jan 15; 507(1):69-84. PMID: 2302582.
      View in: PubMed
    150. MacDonald JF, Bartlett MC, Mody I, Reynolds JN, Salter MW. The PCP site of the NMDA receptor complex. Adv Exp Med Biol. 1990; 268:27-34. PMID: 2150154.
      View in: PubMed
    151. Spielman AI, Mody I, Brand JG, Whitney G, MacDonald JF, Salter MW. A method for isolating and patch-clamping single mammalian taste receptor cells. Brain Res. 1989 Dec 04; 503(2):326-9. PMID: 2605526.
      View in: PubMed
    152. MacDonald JF, Mody I, Salter MW. Regulation of N-methyl-D-aspartate receptors revealed by intracellular dialysis of murine neurones in culture. J Physiol. 1989 Jul; 414:17-34. PMID: 2558167; PMCID: PMC1189128.
    153. Mody I, Salter MW, MacDonald JF. Whole-cell voltage-clamp recordings in granule cells acutely isolated from hippocampal slices of adult or aged rats. Neurosci Lett. 1989 Jan 02; 96(1):70-5. PMID: 2538782.
      View in: PubMed
    154. MacDonald JF, Mody I, Salter MW, Pennefather P, Schneiderman JH. The regulation of NMDA receptors in the central nervous system. Prog Neuropsychopharmacol Biol Psychiatry. 1989; 13(3-4):481-8. PMID: 2473487.
      View in: PubMed
    155. Mody I, Salter MW, MacDonald JF. Requirement of NMDA receptor/channels for intracellular high-energy phosphates and the extent of intraneuronal calcium buffering in cultured mouse hippocampal neurons. Neurosci Lett. 1988 Oct 31; 93(1):73-8. PMID: 2850518.
      View in: PubMed
    156. Salter MW, Henry JL. Tachykinins enhance the depression of spinal nociceptive neurons caused by cutaneously applied vibration in the cat. Neuroscience. 1988 Oct; 27(1):243-9. PMID: 2462189.
      View in: PubMed
    157. Salter MW, Henry JL. Purine-induced depression of dorsal horn neurons in the cat spinal cord: enhancement by tachykinins. Neuroscience. 1987 Dec; 23(3):903-15. PMID: 2449638.
      View in: PubMed
    158. Salter MW, Henry JL. Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat. Neuroscience. 1987 Aug; 22(2):631-50. PMID: 3670602.
      View in: PubMed
    159. Salter M, Knowles RG, Pogson CI. Transport of the aromatic amino acids into isolated rat liver cells. Properties of uptake by two distinct systems. Biochem J. 1986 Jan 15; 233(2):499-506. PMID: 3954748; PMCID: PMC1153053.
    160. Salter MW, Henry JL. Effects of adenosine 5'-monophosphate and adenosine 5'-triphosphate on functionally identified units in the cat spinal dorsal horn. Evidence for a differential effect of adenosine 5'-triphosphate on nociceptive vs non-nociceptive units. Neuroscience. 1985 Jul; 15(3):815-25. PMID: 2999643.
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    161. Salter M, Brooke RI, Merskey H, Fichter GF, Kapusianyk DH. Is the temporo-mandibular pain and dysfunction syndrome a disorder of the mind? Pain. 1983 Oct; 17(2):151-66. PMID: 6646794.
      View in: PubMed
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