Arachidonic Acid
"Arachidonic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.
Descriptor ID |
D016718
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MeSH Number(s) |
D10.251.355.255.100.100 D10.251.355.310.166.100
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Concept/Terms |
Arachidonic Acid- Arachidonic Acid
- Vitamin F
- (all-Z)-5,8,11,14-Eicosatetraenoic acid
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Below are MeSH descriptors whose meaning is more general than "Arachidonic Acid".
Below are MeSH descriptors whose meaning is more specific than "Arachidonic Acid".
This graph shows the total number of publications written about "Arachidonic Acid" by people in this website by year, and whether "Arachidonic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1981 | 0 | 1 | 1 | 1982 | 0 | 2 | 2 | 1983 | 0 | 4 | 4 | 1984 | 0 | 2 | 2 | 1987 | 0 | 4 | 4 | 1988 | 0 | 4 | 4 | 1989 | 0 | 2 | 2 | 1990 | 0 | 1 | 1 | 1991 | 0 | 1 | 1 | 1994 | 1 | 1 | 2 | 1995 | 1 | 1 | 2 | 1997 | 1 | 1 | 2 | 2004 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 1 | 0 | 1 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Arachidonic Acid" by people in Profiles.
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Nance D, Campbell RA, Rowley JW, Downie JM, Jorde LB, Kahr WH, Mereby SA, Tolley ND, Zimmerman GA, Weyrich AS, Rondina MT. Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants. J Thromb Haemost. 2016 11; 14(11):2230-2240.
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Turner JM, Field CJ, Goruk S, Wizzard P, Dicken BJ, Bruce A, Wales PW. Platelet Arachidonic Acid Deficiency May Contribute to Abnormal Platelet Function During Parenteral Fish Oil Monotherapy in a Piglet Model. JPEN J Parenter Enteral Nutr. 2016 05; 40(4):587-91.
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Pace-Asciak CR, Li X, Reynaud D, Qiao N, Demin P, Abdelhaleem M. Alterations in eicosanoid levels during U937 bcl-xL tumour growth suppression and recovery in NU/NU mice in vivo-Involvement of phospholipase A2. Prostaglandins Other Lipid Mediat. 2013 Dec; 107:43-7.
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Aprikian O, Reynaud D, Pace-Asciak C, Leone P, Blancher F, Monnard I, Darimont C, Macé K. Neonatal dietary supplementation of arachidonic acid increases prostaglandin levels in adipose tissue but does not promote fat mass development in guinea pigs. . 2007 Nov; 293(5):R2006-12.
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Beharry S, Ackerley C, Corey M, Kent G, Heng YM, Christensen H, Luk C, Yantiss RK, Nasser IA, Zaman M, Freedman SD, Durie PR. Long-term docosahexaenoic acid therapy in a congenic murine model of cystic fibrosis. Am J Physiol Gastrointest Liver Physiol. 2007 Mar; 292(3):G839-48.
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Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, Brown GE, Yaffe MB, Plumb J, Grinstein S, Glogauer M, Gelb MH. Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. J Biol Chem. 2005 Mar 04; 280(9):7519-29.
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Reynaud D, Pace-Asciak CR. Docosahexaenoic acid causes accumulation of free arachidonic acid in rat pineal gland and hippocampus to form hepoxilins from both substrates. Biochim Biophys Acta. 1997 Jun 23; 1346(3):305-16.
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Reynaud D, Pace-Asciak CR. 12-HETE and 12-HPETE potently stimulate intracellular release of calcium in intact human neutrophils. Prostaglandins Leukot Essent Fatty Acids. 1997 Jan; 56(1):9-12.
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Demin P, Reynaud D, Pace-Asciak CR. Extractive derivatization of the 12-lipoxygenase products, hepoxilins, and related compounds into fluorescent anthryl esters for their complete high-performance liquid chromatography profiling in biological systems. Anal Biochem. 1995 Apr 10; 226(2):252-5.
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Reynaud D, Demin PM, Pace-Asciak CR. Enzymatic formation of hepoxilin A3. Adv Prostaglandin Thromboxane Leukot Res. 1995; 23:183-5.
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