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Ruud Verstegen

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentClinical Pharmacology and Toxicology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
ORCID ORCID Icon0000-0001-6638-8405 Additional info
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shimamoto Y, Verstegen RHJ, Mizuno T, Schechter T, Allen U, Ito S. Population pharmacokinetics of vancomycin in paediatric patients with febrile neutropenia and augmented renal clearance: development of new dosing recommendations. J Antimicrob Chemother. 2021 Sep 04. PMID: 34480578.
      View in: PubMed
    2. Cohen N, Galvis Blanco L, Davis A, Kahane A, Mathew M, Schuh S, Kestenbom I, Test G, Pasternak Y, Verstegen RHJ, Jung B, Maguire B, Rached d'Astous S, Rumantir M, Finkelstein Y. Pediatric cannabis intoxication trends in the pre and post-legalization era. Clin Toxicol (Phila). 2021 Jun 17; 1-6. PMID: 34137352.
      View in: PubMed
    3. Correll CK, Shrader P, Dennos A, Phillips T, Shiff NJ, Verstegen RHJ, Beukelman T. Effectiveness and Safety of High-Dose Biologics in Juvenile Idiopathic Arthritis in the Childhood Arthritis and Rheumatology Research Alliance. Arthritis Care Res (Hoboken). 2021 Jun 13. PMID: 34121344.
      View in: PubMed
    4. Cohn I, Manshaei R, Liston E, Okello JBA, Khan R, Curtis MR, Krupski AJ, Jobling RK, Kalbfleisch K, Paton TA, Reuter MS, Hayeems RZ, Verstegen RHJ, Goldman A, Kim RH, Ito S. Assessment of the Implementation of Pharmacogenomic Testing in a Pediatric Tertiary Care Setting. JAMA Netw Open. 2021 May 03; 4(5):e2110446. PMID: 34037732.
      View in: PubMed
    5. Verstegen RHJ, Anderson PO, Ito S. Infant drug exposure via breast milk. Br J Clin Pharmacol. 2020 Aug 29. PMID: 32860456.
      View in: PubMed
    6. Verstegen RHJ, Kusters MAA. Inborn Errors of Adaptive Immunity in Down Syndrome. J Clin Immunol. 2020 08; 40(6):791-806. PMID: 32638194.
      View in: PubMed
    7. Verstegen RHJ, Wang G, Langenberg-Ververgaert KPS, Ren LY, Nulman I. Paternal exposure to recreational drugs before conception and its effect on live-born offspring: A scoping review. Birth Defects Res. 2020 08; 112(13):970-988. PMID: 32431075.
      View in: PubMed
    8. Verstegen RHJ, McMillan R, Feldman BM, Ito S, Laxer RM. Towards therapeutic drug monitoring of TNF inhibitors for children with juvenile idiopathic arthritis: a scoping review. Rheumatology (Oxford). 2020 02 01; 59(2):386-397. PMID: 31335941.
      View in: PubMed
    9. Verstegen RHJ, Ito S. The Future of Precision Medicine. Clin Pharmacol Ther. 2019 11; 106(5):903-906. PMID: 31584718.
      View in: PubMed
    10. Verstegen RHJ, Chang KJJ, Kusters MAA. Clinical implications of immune-mediated diseases in children with Down syndrome. Pediatr Allergy Immunol. 2020 02; 31(2):117-123. PMID: 31599041.
      View in: PubMed
    11. Verstegen RHJ, Aui PM, Watson E, De Jong S, Bartol SJW, Bosco JJ, Cameron PU, Stirling RG, de Vries E, van Dongen JJM, van Zelm MC. Quantification of T-Cell and B-Cell Replication History in Aging, Immunodeficiency, and Newborn Screening. Front Immunol. 2019; 10:2084. PMID: 31543882.
      View in: PubMed
    12. Verstegen RHJ, Ito S. Drugs in lactation. J Obstet Gynaecol Res. 2019 Mar; 45(3):522-531. PMID: 30663176.
      View in: PubMed
    13. Hong Y, Standing ASI, Nanthapisal S, Sebire N, Jolles S, Omoyinmi E, Verstegen RH, Brogan PA, Eleftheriou D. Autoinflammation due to homozygous S208 MEFV mutation. Ann Rheum Dis. 2019 04; 78(4):571-573. PMID: 30355575.
      View in: PubMed
    14. Martial LC, Verstegen RH, Cornelissen EA, Aarnoutse RE, Schreuder MF, Brüggemann RJ. A preliminary study searching for the right dose of tacrolimus in very young (=4 years) renal transplant patients. J Pharm Pharmacol. 2016 Nov; 68(11):1366-1372. PMID: 27669677.
      View in: PubMed
    15. Verstegen RHJ, Driessen GJ, Bartol SJW, van Noesel CJM, Boon L, van der Burg M, van Dongen JJM, de Vries E, van Zelm MC. Defective B-cell memory in patients with Down syndrome. J Allergy Clin Immunol. 2014 Dec; 134(6):1346-1353.e9. PMID: 25159464.
      View in: PubMed
    16. Verstegen RH, van Hout RW, de Vries E. Epidemiology of respiratory symptoms in children with Down syndrome: a nationwide prospective web-based parent-reported study. BMC Pediatr. 2014 Apr 15; 14:103. PMID: 24735352.
      View in: PubMed
    17. Verstegen RH, Borte S, Bok LA, van Zwieten PH, von Döbeln U, Hammarström L, de Vries E. Impact of Down syndrome on the performance of neonatal screening assays for severe primary immunodeficiency diseases. J Allergy Clin Immunol. 2014 Apr; 133(4):1208-11. PMID: 24332217.
      View in: PubMed
    18. Gemen EF, Verstegen RH, Leuvenink J, de Vries E. Increased circulating apoptotic lymphocytes in children with Down syndrome. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1310-2. PMID: 22811045.
      View in: PubMed
    19. Verstegen RH, van Gameren-Oosterom HB, Fekkes M, Dusseldorp E, de Vries E, van Wouwe JP. Significant impact of recurrent respiratory tract infections in children with Down syndrome. Child Care Health Dev. 2013 Nov; 39(6):801-9. PMID: 22774862.
      View in: PubMed
    20. Brouwer KM, Daamen WF, Reijnen D, Verstegen RH, Lammers G, Hafmans TG, Wismans RG, van Kuppevelt TH, Wijnen RM. Repair of surgically created diaphragmatic defect in rat with use of a crosslinked porous collagen scaffold. J Tissue Eng Regen Med. 2013 Jul; 7(7):552-61. PMID: 22589175.
      View in: PubMed
    21. Kusters MA, Verstegen RH, de Vries E. Down syndrome: is it really characterized by precocious immunosenescence? Aging Dis. 2011 Dec; 2(6):538-45. PMID: 22396900.
      View in: PubMed
    22. Verstegen RH, Theodore M, van de Klerk H, Morava E. Lymphatic edema in congenital disorders of glycosylation. JIMD Rep. 2012; 4:113-6. PMID: 23430905.
      View in: PubMed
    23. Verstegen RH, Kusters MA, Gemen EF, DE Vries E. Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help. Pediatr Res. 2010 May; 67(5):563-9. PMID: 20098344.
      View in: PubMed
    24. Kusters MA, Gemen EF, Verstegen RH, Wever PC, DE Vries E. Both normal memory counts and decreased naive cells favor intrinsic defect over early senescence of Down syndrome T lymphocytes. Pediatr Res. 2010 May; 67(5):557-62. PMID: 20098345.
      View in: PubMed
    25. Kusters MA, Verstegen RH, Gemen EF, de Vries E. Intrinsic defect of the immune system in children with Down syndrome: a review. Clin Exp Immunol. 2009 May; 156(2):189-93. PMID: 19250275.
      View in: PubMed
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