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Earl Silverman

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentRheumatology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Webber D, Cao J, Dominguez D, Gladman DD, Levy DM, Ng L, Paterson AD, Touma Z, Urowitz MB, Wither JE, Silverman ED, Hiraki LT. Association of systemic lupus erythematosus (SLE) genetic susceptibility loci with lupus nephritis in childhood-onset and adult-onset SLE. Rheumatology (Oxford). 2019 Jun 24. PMID: 31236574.
      View in: PubMed
    2. Silverman ED. Canadian Rheumatology Association Meeting Fairmont The Queen Elizabeth Montreal, Quebec, Canada February - March 2, 2019. J Rheumatol. 2019 Jun 01. PMID: 31154408.
      View in: PubMed
    3. Ong Tone S, Elbaz U, Silverman E, Levy D, Williams S, Mireskandari K, Ali A. Evaluation of Dry Eye Disease in Children With Systemic Lupus Erythematosus and Healthy Controls. Cornea. 2019 May; 38(5):581-586. PMID: 30933962.
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    4. Kim H, Levy DM, Silverman ED, Hitchon C, Bernatsky S, Pineau C, Smith CD, Tucker L, Petty R, Arbillaga H, Zummer M, Hudson M, Fortin P, Huber AM, Chedeville G, Peschken C, Pope JE. A comparison between childhood and adult onset systemic lupus erythematosus adjusted for ethnicity from the 1000 Canadian Faces of Lupus Cohort. Rheumatology (Oxford). 2019 Feb 25. PMID: 30805629.
      View in: PubMed
    5. Tao JJ, Hiraki LT, Levy DM, Silverman ED. Comparison of Sensitivities of American College of Rheumatology and Systemic Lupus International Collaborating Clinics Classification Criteria in Childhood-onset Systemic Lupus Erythematosus. J Rheumatol. 2019 Jul; 46(7):731-738. PMID: 30770510.
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    6. Mackay M, Dall'Era M, Fishbein J, Kalunian K, Lesser M, Sanchez-Guerrero J, Levy DM, Silverman E, Petri M, Arriens C, Lewis EJ, Korbet SM, Conti F, Tesar V, Hruskova Z, Borba EF, Bonfa E, Chan TM, Rathi M, Gupta KL, Jha V, Hasni S, West MR, Solomons N, Houssiau FA, Romero-Diaz J, Mejia-Vilet J, Rovin BH. Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes. Arthritis Rheumatol. 2019 Mar; 71(3):411-419. PMID: 30225865.
      View in: PubMed
    7. Baglaenko Y, Chang NH, Johnson SR, Hafiz W, Manion K, Ferri D, Noamani B, Bonilla D, Rusta-Sellehy S, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C, Wither J. The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease. Arthritis Res Ther. 2018 11 29; 20(1):264. PMID: 30486869.
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    8. Barsalou J, Costedoat-Chalumeau N, Berhanu A, Fors-Nieves C, Shah U, Brown P, Laskin CA, Morel N, Levesque K, Buyon JP, Silverman ED, Izmirly PM. Effect of in utero hydroxychloroquine exposure on the development of cutaneous neonatal lupus erythematosus. Ann Rheum Dis. 2018 12; 77(12):1742-1749. PMID: 30297329.
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    9. Peschken CA, Wang Y, Abrahamowicz M, Pope J, Silverman E, Sayani A, Iczkovitz S, Ross J, Zummer M, Tucker L, Pineau C, Levy D, Hudson M, Hitchon CA, Huber AM, Smith CD, Avina-Zubieta A, Arbillaga H, Chédeville G, Wynant W, Fortin PR. Persistent Disease Activity Remains a Burden for Patients with Systemic Lupus Erythematosus. J Rheumatol. 2019 Feb; 46(2):166-175. PMID: 30219771.
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    10. Keeling SO, Alabdurubalnabi Z, Avina-Zubieta A, Barr S, Bergeron L, Bernatsky S, Bourre-Tessier J, Clarke A, Baril-Dionne A, Dutz J, Ensworth S, Fifi-Mah A, Fortin PR, Gladman DD, Haaland D, Hanly JG, Hiraki LT, Hussein S, Legault K, Levy D, Lim L, Matsos M, McDonald EG, Medina-Rosas J, Pardo Pardi J, Peschken C, Pineau C, Pope J, Rader T, Reynolds J, Silverman E, Tselios K, Suitner M, Urowitz M, Touma Z, Vinet E, Santesso N. Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus. J Rheumatol. 2018 Oct; 45(10):1426-1439. PMID: 30173152.
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    11. Patel ZH, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Martin J, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA, Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA, Alarcón-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, Harley JB, Kottyan LC. A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 Jul 01; 27(13):2392-2404. PMID: 29912393.
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    12. Bhattacharya J, Pappas K, Toz B, Aranow C, Mackay M, Gregersen PK, Doumbo O, Traore AK, Lesser ML, McMahon M, Utset T, Silverman E, Levy D, McCune WJ, Jolly M, Wallace D, Weisman M, Romero-Diaz J, Diamond B. Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus. Mol Med. 2018 06 01; 24(1):24. PMID: 30134810.
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    13. Lim LSH, Pullenayegum E, Feldman BM, Lim L, Gladman DD, Silverman ED. From Childhood to Adulthood: Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2018 05; 70(5):750-757. PMID: 28704581.
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    14. Okihiro A, Hasija R, Fung L, Cameron B, Feldman BM, Laxer R, Schneider R, Silverman E, Spiegel L, Yeung RSM, Tse SML. Development of neoplasms in pediatric patients with rheumatic disease exposed to anti-tumor necrosis factor therapies: a single Centre retrospective study. Pediatr Rheumatol Online J. 2018 Mar 14; 16(1):17. PMID: 29540190.
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    15. Borgia RE, Gerstein M, Levy DM, Silverman ED, Hiraki LT. Features, Treatment, and Outcomes of Macrophage Activation Syndrome in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Rheumatol. 2018 04; 70(4):616-624. PMID: 29342508.
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    16. Tian SY, Silverman ED, Pullenayegum E, Brown PE, Beyene J, Feldman BM. Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile-Onset Proliferative Lupus Nephritis. Arthritis Care Res (Hoboken). 2017 12; 69(12):1887-1894. PMID: 28182833.
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    17. Lim LSH, Pullenayegum E, Lim L, Gladman D, Feldman B, Silverman E. From Childhood to Adulthood: The Trajectory of Damage in Patients With Juvenile-Onset Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2017 11; 69(11):1627-1635. PMID: 28118527.
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    18. Barsalou J, Jaeggi E, Laskin CA, Brown P, Tian SY, Hamilton RM, Silverman ED. Prenatal exposure to antimalarials decreases the risk of cardiac but not non-cardiac neonatal lupus: a single-centre cohort study. Rheumatology (Oxford). 2017 09 01; 56(9):1552-1559. PMID: 28595349.
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    19. Guzman J, Kerr T, Ward LM, Ma J, Oen K, Rosenberg AM, Feldman BM, Boire G, Houghton K, Dancey P, Scuccimarri R, Bruns A, Huber AM, Watanabe Duffy K, Shiff NJ, Berard RA, Levy DM, Stringer E, Morishita K, Johnson N, Cabral DA, Larché M, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Roth J, Campillo S, Benseler S, Chédeville G, Schneider R, Tse SML, Bolaria R, Gross K, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RSM, Duffy CM, Tucker LB. Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Pediatr Rheumatol Online J. 2017 Aug 22; 15(1):68. PMID: 28830457.
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    20. Lionel AC, Costain G, Monfared N, Walker S, Reuter MS, Hosseini SM, Thiruvahindrapuram B, Merico D, Jobling R, Nalpathamkalam T, Pellecchia G, Sung WWL, Wang Z, Bikangaga P, Boelman C, Carter MT, Cordeiro D, Cytrynbaum C, Dell SD, Dhir P, Dowling JJ, Heon E, Hewson S, Hiraki L, Inbar-Feigenberg M, Klatt R, Kronick J, Laxer RM, Licht C, MacDonald H, Mercimek-Andrews S, Mendoza-Londono R, Piscione T, Schneider R, Schulze A, Silverman E, Siriwardena K, Snead OC, Sondheimer N, Sutherland J, Vincent A, Wasserman JD, Weksberg R, Shuman C, Carew C, Szego MJ, Hayeems RZ, Basran R, Stavropoulos DJ, Ray PN, Bowdin S, Meyn MS, Cohn RD, Scherer SW, Marshall CR. Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test. Genet Med. 2018 04; 20(4):435-443. PMID: 28771251.
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    21. Bernatsky S, Clarke AE, Zahedi Niaki O, Labrecque J, Schanberg LE, Silverman ED, Hayward K, Imundo L, Brunner HI, Haines KA, Cron RQ, Oen K, Wagner-Weiner L, Rosenberg AM, O'Neil KM, Duffy CM, von Scheven E, Joseph L, Lee JL, Ramsey-Goldman R. Malignancy in Pediatric-onset Systemic Lupus Erythematosus. J Rheumatol. 2017 Oct; 44(10):1484-1486. PMID: 28765255.
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    22. Hiraki LT, Silverman ED. Genomics of Systemic Lupus Erythematosus: Insights Gained by Studying Monogenic Young-Onset Systemic Lupus Erythematosus. Rheum Dis Clin North Am. 2017 08; 43(3):415-434. PMID: 28711143.
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    23. Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021. PMID: 28714469.
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    24. Brunner HI, Ruperto N, Tzaribachev N, Horneff G, Chasnyk VG, Panaviene V, Abud-Mendoza C, Reiff A, Alexeeva E, Rubio-Pérez N, Keltsev V, Kingsbury DJ, Del Rocio Maldonado Velázquez M, Nikishina I, Silverman ED, Joos R, Smolewska E, Bandeira M, Minden K, van Royen-Kerkhof A, Emminger W, Foeldvari I, Lauwerys BR, Sztajnbok F, Gilmer KE, Xu Z, Leu JH, Kim L, Lamberth SL, Loza MJ, Lovell DJ, Martini A. Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial. Ann Rheum Dis. 2018 Jan; 77(1):21-29. PMID: 28507219.
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    25. Silverman ED. Canadian Rheumatology Association Meeting, The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017. J Rheumatol. 2017 May 01. PMID: 28461649.
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    26. Lim LS, Pullenayegum E, Moineddin R, Gladman DD, Silverman ED, Feldman BM. Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review & worked example using a clinic-based cohort of juvenile dermatomyositis patients. Pediatr Rheumatol Online J. 2017 Mar 29; 15(1):18. PMID: 28356102.
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    27. Wither J, Johnson SR, Liu T, Noamani B, Bonilla D, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C. Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis. Arthritis Res Ther. 2017 02 28; 19(1):41. PMID: 28245862.
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    28. Kan N, Silverman ED, Kingdom J, Dutil N, Laskin C, Jaeggi E. Serial echocardiography for immune-mediated heart disease in the fetus: results of a risk-based prospective surveillance strategy. Prenat Diagn. 2017 Apr; 37(4):375-382. PMID: 28177533.
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    29. Pigott YH, Rodrigo CM, Silverman ED. Back to the Future of Rheumatology. J Rheumatol. 2017 02; 44(2):140-141. PMID: 28148753.
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    30. George A, Wong-Pack A, Peschken CA, Silverman E, Pineau C, Smith CD, Arbillaga H, Zummer M, Bernatsky S, Hudson M, Hitchon C, Fortin PR, Nevskaya T, Pope JE. Influence of Education on Disease Activity and Damage in Systemic Lupus Erythematosus: Data From the 1000 Canadian Faces of Lupus. Arthritis Care Res (Hoboken). 2017 Jan; 69(1):124-132. PMID: 27110869.
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    31. Harrington J, Holmyard D, Silverman E, Sochett E, Grynpas M. Bone histomorphometric changes in children with rheumatic disorders on chronic glucocorticoids. Pediatr Rheumatol Online J. 2016 Nov 10; 14(1):58. PMID: 27832795.
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    32. Couture J, Silverman ED. Update on the pathogenesis and treatment of childhood-onset systemic lupus erythematosus. Curr Opin Rheumatol. 2016 09; 28(5):488-96. PMID: 27341622.
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    33. Silverman ED. Canadian Rheumatology Association Meeting, Fairmont Chateau Lake Louise, Lake Louise, Alberta, Canada, February 17-20, 2016. J Rheumatol. 2016 06; 43(6):1149-1250. PMID: 27084909.
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    34. Moots RJ, Wilson K, Silverman ED. Ghost busting--taking the sheet off the ghost. Clin Rheumatol. 2016 Apr; 35(4):841-2. PMID: 26895628.
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    35. Moots RJ, Wilson K, Silverman ED. Ghost busting--taking the sheet off the ghost. Z Rheumatol. 2016 Apr; 75(3):240-1. PMID: 27038049.
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    36. Moots RJ, Wilson K, Silverman ED. Ghost Busting, Taking the Sheet Off the Ghost. J Rheumatol. 2016 Apr; 43(4):689-90. PMID: 26879351.
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    37. Moots RJ, Wilson K, Silverman ED. Ghostbusting-taking the sheet off the ghost. Rheumatology (Oxford). 2016 Apr; 55(4):597-8. PMID: 26876339.
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    38. Barsalou J, Bradley TJ, Tyrrell PN, Slorach C, Ng LW, Levy DM, Silverman ED. Impact of Disease Duration on Vascular Surrogates of Early Atherosclerosis in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Rheumatol. 2016 Jan; 68(1):237-46. PMID: 26361097.
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    39. Yang Y, Kumar S, Lim LS, Silverman ED, Levy DM. Risk Factors for Symptomatic Avascular Necrosis in Childhood-onset Systemic Lupus Erythematosus. J Rheumatol. 2015 Dec; 42(12):2304-9. PMID: 26568601.
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    40. Schmeling H, Mahler M, Levy DM, Moore K, Stevens AM, Wick J, McMillan JD, Horneff G, Assassi S, Charles J, Salazar G, Mayes MD, Silverman ED, Klien-Gitelman M, Lee T, Brunner HI, Reed AM, Fritzler MJ. Autoantibodies to Dense Fine Speckles in Pediatric Diseases and Controls. J Rheumatol. 2015 Dec; 42(12):2419-26. PMID: 26472409.
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    41. Borgia RE, Silverman ED. Childhood-onset systemic lupus erythematosus: an update. Curr Opin Rheumatol. 2015 Sep; 27(5):483-92. PMID: 26200474.
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    42. Tian SY, Feldman BM, Beyene J, Brown PE, Uleryk EM, Silverman ED. Immunosuppressive Therapies for the Maintenance Treatment of Proliferative Lupus Nephritis: A Systematic Review and Network Metaanalysis. J Rheumatol. 2015 Aug; 42(8):1392-400. PMID: 26077406.
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    43. Guzman J, Oen K, Huber AM, Watanabe Duffy K, Boire G, Shiff N, Berard RA, Levy DM, Stringer E, Scuccimarri R, Morishita K, Johnson N, Cabral DA, Rosenberg AM, Larché M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Bruns A, Roth J, Campillo S, Benseler S, Chédeville G, Schneider R, Tse SM, Bolaria R, Gross K, Feldman B, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RS, Duffy CM, Tucker LB. The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Ann Rheum Dis. 2016 06; 75(6):1092-8. PMID: 25985972.
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    44. Taylor JC, Martin HC, Lise S, Broxholme J, Cazier JB, Rimmer A, Kanapin A, Lunter G, Fiddy S, Allan C, Aricescu AR, Attar M, Babbs C, Becq J, Beeson D, Bento C, Bignell P, Blair E, Buckle VJ, Bull K, Cais O, Cario H, Chapel H, Copley RR, Cornall R, Craft J, Dahan K, Davenport EE, Dendrou C, Devuyst O, Fenwick AL, Flint J, Fugger L, Gilbert RD, Goriely A, Green A, Greger IH, Grocock R, Gruszczyk AV, Hastings R, Hatton E, Higgs D, Hill A, Holmes C, Howard M, Hughes L, Humburg P, Johnson D, Karpe F, Kingsbury Z, Kini U, Knight JC, Krohn J, Lamble S, Langman C, Lonie L, Luck J, McCarthy D, McGowan SJ, McMullin MF, Miller KA, Murray L, Németh AH, Nesbit MA, Nutt D, Ormondroyd E, Oturai AB, Pagnamenta A, Patel SY, Percy M, Petousi N, Piazza P, Piret SE, Polanco-Echeverry G, Popitsch N, Powrie F, Pugh C, Quek L, Robbins PA, Robson K, Russo A, Sahgal N, van Schouwenburg PA, Schuh A, Silverman E, Simmons A, Sørensen PS, Sweeney E, Taylor J, Thakker RV, Tomlinson I, Trebes A, Twigg SR, Uhlig HH, Vyas P, Vyse T, Wall SA, Watkins H, Whyte MP, Witty L, Wright B, Yau C, Buck D, Humphray S, Ratcliffe PJ, Bell JI, Wilkie AO, Bentley D, Donnelly P, McVean G. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nat Genet. 2015 Jul; 47(7):717-726. PMID: 25985138.
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    45. Silverman ED. 70th Annual Meeting of the Canadian Rheumatology Association, Quebec City, Quebec, Canada, February 4-7, 2015. J Rheumatol. 2015 May 15. PMID: 25979717.
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    46. Mohan S, Barsalou J, Bradley TJ, Slorach C, Reynolds JA, Hasni S, Thompson B, Ng L, Levy D, Silverman E, Kaplan MJ. Endothelial progenitor cell phenotype and function are impaired in childhood-onset systemic lupus erythematosus. Arthritis Rheumatol. 2015 May; 67(8):2257-62. PMID: 25891295.
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    47. Olfat M, Silverman ED, Levy DM. Rituximab therapy has a rapid and durable response for refractory cytopenia in childhood-onset systemic lupus erythematosus. Lupus. 2015 Aug; 24(9):966-72. PMID: 25804672.
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    48. Rozenblyum EV, Levy DM, Allen U, Harvey E, Hebert D, Silverman ED. Cytomegalovirus in pediatric systemic lupus erythematosus: prevalence and clinical manifestations. Lupus. 2015 Jun; 24(7):730-5. PMID: 25568145.
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    49. Levy DM, Peschken CA, Tucker LB, Chédeville G, Huber AM, Pope JE, Silverman ED. Association of health-related quality of life in childhood-onset systemic lupus erythematosus with ethnicity: results from a multiethnic multicenter Canadian cohort. Arthritis Care Res (Hoboken). 2014 Dec; 66(12):1767-74. PMID: 24821613.
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    50. van den Akker M, Silverman E, Abdelhaleem M, Kirby-Allen M. Aplastic anemia associated with systemic lupus erythematosus in children - case report and review of the literature. Clin Case Rep. 2014 Dec; 2(6):319-22. PMID: 25548637.
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    51. Lim LS, Lee SJ, Feldman BM, Gladman DD, Pullenayegum E, Uleryk E, Silverman ED. Systematic review of the quality of prognosis studies in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2014 Oct; 66(10):1536-41. PMID: 24643975.
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    52. Tian SY, Feldman BM, Beyene J, Brown PE, Uleryk EM, Silverman ED. Immunosuppressive therapies for the induction treatment of proliferative lupus nephritis: a systematic review and network metaanalysis. J Rheumatol. 2014 Oct; 41(10):1998-2007. PMID: 25225281.
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    53. Kelly EN, Sananes R, Chiu-Man C, Silverman ED, Jaeggi E. Prenatal anti-Ro antibody exposure, congenital complete atrioventricular heart block, and high-dose steroid therapy: impact on neurocognitive outcome in school-age children. Arthritis Rheumatol. 2014 Aug; 66(8):2290-6. PMID: 24756962.
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    54. Hugle B, Silverman ED, Tyrrell PN, Harvey EA, Hébert D, Benseler SM. Presentation and outcome of paediatric membranous non-proliferative lupus nephritis. Pediatr Nephrol. 2015 Jan; 30(1):113-21. PMID: 25080370.
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    55. Guzman J, Oen K, Tucker LB, Huber AM, Shiff N, Boire G, Scuccimarri R, Berard R, Tse SM, Morishita K, Stringer E, Johnson N, Levy DM, Duffy KW, Cabral DA, Rosenberg AM, Larché M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey S, Bruns A, Campillo S, Benseler S, Chédeville G, Schneider R, Yeung R, Duffy CM. The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort. Ann Rheum Dis. 2015 Oct; 74(10):1854-60. PMID: 24842571.
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    56. Brunner HI, Ruperto N, Zuber Z, Keane C, Harari O, Kenwright A, Lu P, Cuttica R, Keltsev V, Xavier RM, Calvo I, Nikishina I, Rubio-Pérez N, Alexeeva E, Chasnyk V, Horneff G, Opoka-Winiarska V, Quartier P, Silva CA, Silverman E, Spindler A, Baildam E, Gámir ML, Martin A, Rietschel C, Siri D, Smolewska E, Lovell D, Martini A, De Benedetti F. Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial. Ann Rheum Dis. 2015 Jun; 74(6):1110-7. PMID: 24834925.
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    57. Toulany A, Katzman DK, Kaufman M, Hiraki LT, Silverman ED. Chicken or the egg: anorexia nervosa and systemic lupus erythematosus in children and adolescents. Pediatrics. 2014 Feb; 133(2):e447-50. PMID: 24394681.
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    58. Bose B, Silverman ED, Bargman JM. Ten common mistakes in the management of lupus nephritis. Am J Kidney Dis. 2014 Apr; 63(4):667-76. PMID: 24332767.
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    59. Lee J, Peschken CA, Muangchan C, Silverman E, Pineau C, Smith CD, Arbillaga H, Zummer M, Clarke A, Bernatsky S, Hudson M, Hitchon C, Fortin PR, Pope JE. The frequency of and associations with hospitalization secondary to lupus flares from the 1000 Faces of Lupus Canadian cohort. Lupus. 2013 Nov; 22(13):1341-8. PMID: 24048215.
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    60. Strandberg LS, Cui X, Rath A, Liu J, Silverman ED, Liu X, Siragam V, Ackerley C, Su BB, Yan JY, Capecchi M, Biavati L, Accorroni A, Yuen W, Quattrone F, Lung K, Jaeggi ET, Backx PH, Deber CM, Hamilton RM. Congenital heart block maternal sera autoantibodies target an extracellular epitope on the a1G T-type calcium channel in human fetal hearts. PLoS One. 2013; 8(9):e72668. PMID: 24039792.
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    65. Greenwald AG, Zakerzadeh A, Laxer RM, Schneider R, Cameron B, Feldman B, Spiegel L, Tse SM, Silverman ED. Later-onset rheumatoid factor negative polyarticular juvenile idiopathic arthritis (JIA): a unique patient group? Clin Exp Rheumatol. 2013 Jul-Aug; 31(4):645-52. PMID: 23622111.
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    66. Butbul Aviel Y, Tyrrell P, Schneider R, Dhillon S, Feldman BM, Laxer R, Saurenmann RK, Spiegel L, Cameron B, Tse SM, Silverman E. Juvenile Psoriatic Arthritis (JPsA): juvenile arthritis with psoriasis? Pediatr Rheumatol Online J. 2013 Mar 15; 11(1):11. PMID: 23497068.
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    67. Lim LS, Lefebvre A, Benseler S, Silverman ED. Longterm outcomes and damage accrual in patients with childhood systemic lupus erythematosus with psychosis and severe cognitive dysfunction. J Rheumatol. 2013 Apr; 40(4):513-9. PMID: 23457384.
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    68. Silverman ED, Inman RD, Kraag G. In memoriam - Duncan A. Gordon, 1930-2012. J Rheumatol. 2013 Mar; 40(3):209-13. PMID: 23457396.
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    71. Rozenblyum EV, Allen UD, Silverman ED, Levy DM. Cytomegalovirus infection in childhood-onset systemic lupus erythematosus. Int J Clin Rheumtol. 2013 Feb; 8(1):137-146. PMID: 24527062.
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    74. Lim L, Lippe S, Silverman E. Effect of autoimmune diseases on cognitive function. Handb Clin Neurol. 2013; 112:1275-83. PMID: 23622338.
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    75. Levy DM, Peschken CA, Tucker LB, Chédeville G, Huber AM, Pope JE, Silverman ED. Influence of ethnicity on childhood-onset systemic lupus erythematosus: results from a multiethnic multicenter Canadian cohort. Arthritis Care Res (Hoboken). 2013 Jan; 65(1):152-60. PMID: 22744999.
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    76. Silverman E. Send us your best. J Rheumatol. 2013 Jan; 40(1):3. PMID: 23280160.
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    78. Manaboriboon B, Silverman ED, Homsanit M, Chui H, Kaufman M. Weight change associated with corticosteroid therapy in adolescents with systemic lupus erythematosus. Lupus. 2013 Feb; 22(2):164-70. PMID: 23223243.
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    79. Miettunen PM, Pistorio A, Palmisani E, Ravelli A, Silverman E, Oliveira S, Alessio M, Cuttica R, Mihaylova D, Espada G, Pasic S, Insalaco A, Ozen S, Porras O, Sztajnbok F, Lazarevic D, Martini A, Ruperto N. Therapeutic approaches for the treatment of renal disease in juvenile systemic lupus erythematosus: an international multicentre PRINTO study. Ann Rheum Dis. 2013 Sep 01; 72(9):1503-9. PMID: 23100607.
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    82. Lim LS, Benseler SM, Tyrrell PN, Harvey E, Herbert D, Charron M, Silverman ED. Predicting longitudinal trajectory of bone mineral density in paediatric systemic lupus erythematosus patients. Ann Rheum Dis. 2012 Oct; 71(10):1686-91. PMID: 22440826.
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    83. Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN, Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chédeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI. Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2012 Mar; 64(3):375-83. PMID: 22162255.
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    84. Schanberg LE, Sandborg C, Barnhart HX, Ardoin SP, Yow E, Evans GW, Mieszkalski KL, Ilowite NT, Eberhard A, Imundo LF, Kimura Y, von Scheven E, Silverman E, Bowyer SL, Punaro M, Singer NG, Sherry DD, McCurdy D, Klein-Gitelman M, Wallace C, Silver R, Wagner-Weiner L, Higgins GC, Brunner HI, Jung L, Soep JB, Reed AM, Provenzale J, Thompson SD. Use of atorvastatin in systemic lupus erythematosus in children and adolescents. Arthritis Rheum. 2012 Jan; 64(1):285-96. PMID: 22031171.
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    85. Jacob CO, Eisenstein M, Dinauer MC, Ming W, Liu Q, John S, Quismorio FP, Reiff A, Myones BL, Kaufman KM, McCurdy D, Harley JB, Silverman E, Kimberly RP, Vyse TJ, Gaffney PM, Moser KL, Klein-Gitelman M, Wagner-Weiner L, Langefeld CD, Armstrong DL, Zidovetzki R. Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):E59-67. PMID: 22203994.
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    87. Lee SJ, Silverman E, Bargman JM. The role of antimalarial agents in the treatment of SLE and lupus nephritis. Nat Rev Nephrol. 2011 Oct 18; 7(12):718-29. PMID: 22009248.
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    90. Jaeggi ET, Silverman ED, Laskin C, Kingdom J, Golding F, Weber R. Prolongation of the atrioventricular conduction in fetuses exposed to maternal anti-Ro/SSA and anti-La/SSB antibodies did not predict progressive heart block. A prospective observational study on the effects of maternal antibodies on 165 fetuses. J Am Coll Cardiol. 2011 Mar 29; 57(13):1487-92. PMID: 21435519.
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    91. Trucco SM, Jaeggi E, Cuneo B, Moon-Grady AJ, Silverman E, Silverman N, Hornberger LK. Use of intravenous gamma globulin and corticosteroids in the treatment of maternal autoantibody-mediated cardiomyopathy. J Am Coll Cardiol. 2011 Feb 08; 57(6):715-23. PMID: 21292131.
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    92. Ardoin SP, Schanberg LE, Sandborg C, Yow E, Barnhart HX, Mieszkalski Kl, Ilowite NT, von Scheven E, Eberhard A, Levy DM, Kimura Y, Silverman E, Bowyer SL, Punaro L, Singer NG, Sherry DD, McCurdy D, Klein-Gitelman M, Wallace C, Silver R, Wagner-Weiner L, Higgins GC, Brunner HI, Jung LK, Imundo L, Soep JB, Reed AM. Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort. Lupus. 2010 Oct; 19(11):1315-25. PMID: 20861207.
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    96. Mahler M, Silverman ED, Fritzler MJ. Novel diagnostic and clinical aspects of anti-PCNA antibodies detected by novel detection methods. Lupus. 2010 Nov; 19(13):1527-33. PMID: 20647252.
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    97. Mahler M, Silverman ED, Schulte-Pelkum J, Fritzler MJ. Anti-Scl-70 (topo-I) antibodies in SLE: Myth or reality? Autoimmun Rev. 2010 Sep; 9(11):756-60. PMID: 20601198.
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    99. Saurenmann RK, Levin AV, Feldman BM, Laxer RM, Schneider R, Silverman ED. Risk factors for development of uveitis differ between girls and boys with juvenile idiopathic arthritis. Arthritis Rheum. 2010 Jun; 62(6):1824-8. PMID: 20178126.
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    100. Ruperto N, Lovell DJ, Cuttica R, Woo P, Meiorin S, Wouters C, Silverman ED, Balogh Z, Henrickson M, Davidson J, Foeldvari I, Imundo L, Simonini G, Oppermann J, Xu S, Shen YK, Visvanathan S, Fasanmade A, Mendelsohn A, Martini A, Giannini EH. Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: findings from an open-label treatment extension. Ann Rheum Dis. 2010 Apr; 69(4):718-22. PMID: 20237125.
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    101. Oen K, Duffy CM, Tse SM, Ramsey S, Ellsworth J, Chédeville G, Chetaille AL, Saint-Cyr C, Cabral DA, Spiegel LR, Schneider R, Lang B, Huber AM, Dancey P, Silverman E, Rosenberg AM, Cameron B, Johnson N, Dorval J, Scuccimarri R, Campillo S, Petty RE, Duffy KN, Boire G, Haddad E, Houghton K, Laxer R, Turvey SE, Miettunen P, Gross K, Guzman J, Benseler S, Feldman BM, Espinosa V, Yeung RS, Tucker L. Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort. Arthritis Care Res (Hoboken). 2010 Apr; 62(4):527-36. PMID: 20391508.
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    102. Tyrrell PN, Beyene J, Feldman BM, McCrindle BW, Silverman ED, Bradley TJ. Rheumatic disease and carotid intima-media thickness: a systematic review and meta-analysis. Arterioscler Thromb Vasc Biol. 2010 May; 30(5):1014-26. PMID: 20150560.
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    103. Mittoo S, Gelber AC, Hitchon CA, Silverman ED, Pope JE, Fortin PR, Pineau C, Smith CD, Arbillaga H, Gladman DD, Urowitz MB, Zummer M, Clarke AE, Bernatsky S, Hudson M, Tucker LB, Petty RE, Peschken CA. Clinical and serologic factors associated with lupus pleuritis. J Rheumatol. 2010 Apr; 37(4):747-53. PMID: 20110526.
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    104. Baker K, Pope J, Fortin P, Silverman E, Peschken C. Work disability in systemic lupus erythematosus is prevalent and associated with socio-demographic and disease related factors. Lupus. 2009 Dec; 18(14):1281-8. PMID: 19854811.
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    105. Hiraki LT, Benseler SM, Tyrrell PN, Harvey E, Hebert D, Silverman ED. Ethnic differences in pediatric systemic lupus erythematosus. J Rheumatol. 2009 Nov; 36(11):2539-46. PMID: 19833755.
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    106. Hinze CH, Suzuki M, Klein-Gitelman M, Passo MH, Olson J, Singer NG, Haines KA, Onel K, O'Neil K, Silverman ED, Tucker L, Ying J, Devarajan P, Brunner HI. Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity. Arthritis Rheum. 2009 Sep; 60(9):2772-81. PMID: 19714584.
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    108. Butbul YA, Tyrrell PN, Schneider R, Dhillon S, Feldman BM, Laxer RM, Saurenmann RK, Spiegel L, Cameron B, Tse SM, Silverman ED. Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they? J Rheumatol. 2009 Sep; 36(9):2033-41. PMID: 19648305.
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    109. Jaeggi ET, Golding F, Silverman ED. Letter by Jaeggi et al regarding article, "Perinatal outcome of fetal atrioventricular block: one-hundred sixteen cases from a single institution". Circulation. 2009 May 26; 119(20):e539; author reply e541-2. PMID: 19470895.
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    112. Suzuki M, Wiers K, Brooks EB, Greis KD, Haines K, Klein-Gitelman MS, Olson J, Onel K, O'Neil KM, Silverman ED, Tucker L, Ying J, Devarajan P, Brunner HI. Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatr Res. 2009 May; 65(5):530-6. PMID: 19218887.
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    117. Benseler SM, Bargman JM, Feldman BM, Tyrrell PN, Harvey E, Hebert D, Silverman ED. Acute renal failure in paediatric systemic lupus erythematosus: treatment and outcome. Rheumatology (Oxford). 2009 Feb; 48(2):176-82. PMID: 19141574.
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    120. Kumar S, Benseler SM, Kirby-Allen M, Silverman ED. B-cell depletion for autoimmune thrombocytopenia and autoimmune hemolytic anemia in pediatric systemic lupus erythematosus. Pediatrics. 2009 Jan; 123(1):e159-63. PMID: 19074962.
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    125. Urowitz MB, Gladman DD, MacKinnon A, Ibañez D, Bruto V, Rovet J, Silverman E. Neurocognitive abnormalities in offspring of mothers with systemic lupus erythematosus. Lupus. 2008 Jun; 17(6):555-60. PMID: 18539709.
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    134. Benseler SM, Silverman ED. Systemic lupus erythematosus. Rheum Dis Clin North Am. 2007 Aug; 33(3):471-98, vi. PMID: 17936174.
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    135. Akikusa JD, Schneider R, Harvey EA, Hebert D, Thorner PS, Laxer RM, Silverman ED. Clinical features and outcome of pediatric Wegener's granulomatosis. Arthritis Rheum. 2007 Jun 15; 57(5):837-44. PMID: 17530684.
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    136. Compeyrot-Lacassagne S, Tyrrell PN, Atenafu E, Doria AS, Stephens D, Gilday D, Silverman ED. Prevalence and etiology of low bone mineral density in juvenile systemic lupus erythematosus. Arthritis Rheum. 2007 Jun; 56(6):1966-73. PMID: 17530722.
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    137. Saurenmann RK, Rose JB, Tyrrell P, Feldman BM, Laxer RM, Schneider R, Silverman ED. Epidemiology of juvenile idiopathic arthritis in a multiethnic cohort: ethnicity as a risk factor. Arthritis Rheum. 2007 Jun; 56(6):1974-84. PMID: 17530723.
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    138. Boros CA, Spence D, Blaser S, Silverman ED. Hydrocephalus and macrocephaly: new manifestations of neonatal lupus erythematosus. Arthritis Rheum. 2007 Mar 15; 57(2):261-6. PMID: 17330304.
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    139. Akikusa JD, Feldman BM, Gross GJ, Silverman ED, Schneider R. Sinus bradycardia after intravenous pulse methylprednisolone. Pediatrics. 2007 Mar; 119(3):e778-82. PMID: 17308245.
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    140. Sarkissian T, Beyene J, Feldman B, McCrindle B, Silverman ED. Longitudinal examination of lipid profiles in pediatric systemic lupus erythematosus. Arthritis Rheum. 2007 Feb; 56(2):631-8. PMID: 17265498.
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    141. Saurenmann RK, Levin AV, Feldman BM, Rose JB, Laxer RM, Schneider R, Silverman ED. Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: a long-term followup study. Arthritis Rheum. 2007 Feb; 56(2):647-57. PMID: 17265500.
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    142. Aviv RI, Benseler SM, DeVeber G, Silverman ED, Tyrrell PN, Tsang LM, Armstrong D. Angiography of primary central nervous system angiitis of childhood: conventional angiography versus magnetic resonance angiography at presentation. AJNR Am J Neuroradiol. 2007 Jan; 28(1):9-15. PMID: 17213414.
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    143. Avcin T, Singh-Grewal D, Silverman ED, Schneider R. Severe digital ischaemia in a child with Wegener's granulomatosis. Scand J Rheumatol. 2007 Jan-Feb; 36(1):78-80. PMID: 17454943.
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    144. Benseler SM, Silverman ED. Neuropsychiatric involvement in pediatric systemic lupus erythematosus. Lupus. 2007; 16(8):564-71. PMID: 17711889.
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    145. Avcin T, Silverman ED. Antiphospholipid antibodies in pediatric systemic lupus erythematosus and the antiphospholipid syndrome. Lupus. 2007; 16(8):627-33. PMID: 17711899.
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    146. Hiraki LT, Hamilton J, Silverman ED. Measuring permanent damage in pediatric systemic lupus erythematosus. Lupus. 2007; 16(8):657-62. PMID: 17711904.
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    147. Saurenmann RK, Levin AV, Feldman BM, Laxer RM, Schneider R, Silverman ED. Risk of new-onset uveitis in patients with juvenile idiopathic arthritis treated with anti-TNFalpha agents. J Pediatr. 2006 Dec; 149(6):833-6. PMID: 17137902.
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    148. Levine D, Akikusa J, Manson D, Silverman E, Schneider R. Chest CT findings in pediatric Wegener's granulomatosis. Pediatr Radiol. 2007 Jan; 37(1):57-62. PMID: 17072611.
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    149. Avcin T, Tse SM, Schneider R, Ngan B, Silverman ED. Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood. J Pediatr. 2006 May; 148(5):683-6. PMID: 16737887.
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    150. Chagnon P, Schneider R, Hébert J, Fortin PR, Provost S, Belisle C, Gingras M, Bolduc V, Perreault C, Silverman E, Busque L. Identification and characterization of an Xp22.33;Yp11.2 translocation causing a triplication of several genes of the pseudoautosomal region 1 in an XX male patient with severe systemic lupus erythematosus. Arthritis Rheum. 2006 Apr; 54(4):1270-8. PMID: 16575839.
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    151. Sarkissian T, Beyenne J, Feldman B, Adeli K, Silverman E. The complex nature of the interaction between disease activity and therapy on the lipid profile in patients with pediatric systemic lupus erythematosus. Arthritis Rheum. 2006 Apr; 54(4):1283-90. PMID: 16575849.
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    152. Benseler SM, Silverman E, Aviv RI, Schneider R, Armstrong D, Tyrrell PN, deVeber G. Primary central nervous system vasculitis in children. Arthritis Rheum. 2006 Apr; 54(4):1291-7. PMID: 16575852.
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    153. Lang BA, Yeung RS, Oen KG, Malleson PN, Huber AM, Riley M, Ebbeson R, Ramsey SE, Laxer RM, Silverman ED, McCrindle BW, Ratnapalan S, Feldman BM. Corticosteroid treatment of refractory Kawasaki disease. J Rheumatol. 2006 Apr; 33(4):803-9. PMID: 16583481.
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    154. Saurenmann RK, Levin AV, Rose JB, Parker S, Rabinovitch T, Tyrrell PN, Feldman BM, Laxer RM, Schneider R, Silverman ED. Tumour necrosis factor alpha inhibitors in the treatment of childhood uveitis. Rheumatology (Oxford). 2006 Aug; 45(8):982-9. PMID: 16461435.
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    155. Aviv RI, Benseler SM, Silverman ED, Tyrrell PN, Deveber G, Tsang LM, Armstrong D. MR imaging and angiography of primary CNS vasculitis of childhood. AJNR Am J Neuroradiol. 2006 Jan; 27(1):192-9. PMID: 16418382.
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    156. Benseler SM, McCrindle BW, Silverman ED, Tyrrell PN, Wong J, Yeung RS. Infections and Kawasaki disease: implications for coronary artery outcome. Pediatrics. 2005 Dec; 116(6):e760-6. PMID: 16322132.
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    157. Avcin T, Silverman ED, Forte V, Schneider R. Nasal septal perforation: a novel clinical manifestation of systemic juvenile idiopathic arthritis/adult onset Still's disease. J Rheumatol. 2005 Dec; 32(12):2429-31. PMID: 16331776.
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    158. Spence D, Hornberger L, Hamilton R, Silverman ED. Increased risk of complete congenital heart block in infants born to women with hypothyroidism and anti-Ro and/or anti-La antibodies. J Rheumatol. 2006 Jan; 33(1):167-70. PMID: 16292791.
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    159. Ramanan AV, Campbell-Webster N, Ota S, Parker S, Tran D, Tyrrell PN, Cameron B, Spiegel L, Schneider R, Laxer RM, Silverman ED, Feldman BM. The effectiveness of treating juvenile dermatomyositis with methotrexate and aggressively tapered corticosteroids. Arthritis Rheum. 2005 Nov; 52(11):3570-8. PMID: 16255046.
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    160. Male C, Foulon D, Hoogendoorn H, Vegh P, Silverman E, David M, Mitchell L. Predictive value of persistent versus transient antiphospholipid antibody subtypes for the risk of thrombotic events in pediatric patients with systemic lupus erythematosus. Blood. 2005 Dec 15; 106(13):4152-8. PMID: 16144797.
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    161. Benseler SM, deVeber G, Hawkins C, Schneider R, Tyrrell PN, Aviv RI, Armstrong D, Laxer RM, Silverman ED. Angiography-negative primary central nervous system vasculitis in children: a newly recognized inflammatory central nervous system disease. Arthritis Rheum. 2005 Jul; 52(7):2159-67. PMID: 15986347.
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    162. Levy DM, Silverman ED, Massicotte MP, McCrindle BW, Yeung RS. Longterm outcomes in patients with giant aneurysms secondary to Kawasaki disease. J Rheumatol. 2005 May; 32(5):928-34. PMID: 15868632.
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    163. Silverman E, Mouy R, Spiegel L, Jung LK, Saurenmann RK, Lahdenne P, Horneff G, Calvo I, Szer IS, Simpson K, Stewart JA, Strand V. Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med. 2005 Apr 21; 352(16):1655-66. PMID: 15843668.
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    164. Benseler SM, Silverman ED. Systemic lupus erythematosus. Pediatr Clin North Am. 2005 Apr; 52(2):443-67, vi. PMID: 15820375.
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    165. Mäkitie O, Doria AS, Henriques F, Cole WG, Compeyrot S, Silverman E, Laxer R, Daneman A, Sochett EB. Radiographic vertebral morphology: a diagnostic tool in pediatric osteoporosis. J Pediatr. 2005 Mar; 146(3):395-401. PMID: 15756228.
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    166. Suzuki H, Silverman ED, Wu X, Borges C, Zhao S, Isacovics B, Hamilton RM. Effect of maternal autoantibodies on fetal cardiac conduction: an experimental murine model. Pediatr Res. 2005 Apr; 57(4):557-62. PMID: 15695601.
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    167. Silverman E, Spiegel L, Hawkins D, Petty R, Goldsmith D, Schanberg L, Duffy C, Howard P, Strand V. Long-term open-label preliminary study of the safety and efficacy of leflunomide in patients with polyarticular-course juvenile rheumatoid arthritis. Arthritis Rheum. 2005 Feb; 52(2):554-62. PMID: 15693001.
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    168. Jaeggi ET, Fouron JC, Silverman ED, Ryan G, Smallhorn J, Hornberger LK. Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease. Circulation. 2004 Sep 21; 110(12):1542-8. PMID: 15353508.
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    169. Jaeggi ET, Silverman ED, Yoo SJ, Kingdom J. Is immune-mediated complete fetal atrioventricular block reversible by transplacental dexamethasone therapy? Ultrasound Obstet Gynecol. 2004 Jun; 23(6):602-5. PMID: 15170804.
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    170. Muise A, Tallett SE, Silverman ED. Are children with Kawasaki disease and prolonged fever at risk for macrophage activation syndrome? Pediatrics. 2003 Dec; 112(6 Pt 1):e495. PMID: 14654653.
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    171. Schmugge M, Revel-Vilk S, Hiraki L, Rand ML, Blanchette VS, Silverman ED. Thrombocytopenia and thromboembolism in pediatric systemic lupus erythematosus. J Pediatr. 2003 Nov; 143(5):666-9. PMID: 14615743.
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    172. Ruperto N, Ravelli A, Murray KJ, Lovell DJ, Andersson-Gare B, Feldman BM, Garay S, Kuis W, Machado C, Pachman L, Prieur AM, Rider LG, Silverman E, Tsitsami E, Woo P, Giannini EH, Martini A. Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis. Rheumatology (Oxford). 2003 Dec; 42(12):1452-9. PMID: 12832713.
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    173. Brunner HI, Silverman ED, Bombardier C, Feldman BM. European Consensus Lupus Activity Measurement is sensitive to change in disease activity in childhood-onset systemic lupus erythematosus. Arthritis Rheum. 2003 Jun 15; 49(3):335-41. PMID: 12794788.
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    174. Cimaz R, Spence DL, Hornberger L, Silverman ED. Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies. J Pediatr. 2003 Jun; 142(6):678-83. PMID: 12838197.
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    175. Uziel Y, Berkovitch M, Gazarian M, Koren G, Silverman ED, Schneider R, Laxer RM. Evaluation of eutectic lidocaine/prilocaine cream (EMLA) for steroid joint injection in children with juvenile rheumatoid arthritis: a double blind, randomized, placebo controlled trial. J Rheumatol. 2003 Mar; 30(3):594-6. PMID: 12610822.
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    176. Levy DM, Massicotte MP, Harvey E, Hebert D, Silverman ED. Thromboembolism in paediatric lupus patients. Lupus. 2003; 12(10):741-6. PMID: 14596422.
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    177. Duong TT, Silverman ED, Bissessar MV, Yeung RS. Superantigenic activity is responsible for induction of coronary arteritis in mice: an animal model of Kawasaki disease. Int Immunol. 2003 Jan; 15(1):79-89. PMID: 12502728.
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    178. Honkanen VE, McCrindle BW, Laxer RM, Feldman BM, Schneider R, Silverman ED. Clinical relevance of the risk factors for coronary artery inflammation in Kawasaki disease. Pediatr Cardiol. 2003 Mar-Apr; 24(2):122-6. PMID: 12457252.
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    179. Hagelberg S, Lee Y, Bargman J, Mah G, Schneider R, Laskin C, Eddy A, Gladman D, Urowitz M, Hebert D, Silverman E. Longterm followup of childhood lupus nephritis. J Rheumatol. 2002 Dec; 29(12):2635-42. PMID: 12465165.
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    180. Nield LE, Silverman ED, Smallhorn JF, Taylor GP, Mullen JB, Benson LN, Hornberger LK. Endocardial fibroelastosis associated with maternal anti-Ro and anti-La antibodies in the absence of atrioventricular block. J Am Coll Cardiol. 2002 Aug 21; 40(4):796-802. PMID: 12204513.
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    181. Klein-Gitelman M, Reiff A, Silverman ED. Systemic lupus erythematosus in childhood. Rheum Dis Clin North Am. 2002 Aug; 28(3):561-77, vi-vii. PMID: 12380370.
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    182. Muzaffer MA, Dayer JM, Feldman BM, Pruzanski W, Roux-Lombard P, Schneider R, Laxer RM, Silverman ED. Differences in the profiles of circulating levels of soluble tumor necrosis factor receptors and interleukin 1 receptor antagonist reflect the heterogeneity of the subgroups of juvenile rheumatoid arthritis. J Rheumatol. 2002 May; 29(5):1071-8. PMID: 12022325.
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    183. Tse SM, Silverman ED, McCrindle BW, Yeung RS. Early treatment with intravenous immunoglobulin in patients with Kawasaki disease. J Pediatr. 2002 Apr; 140(4):450-5. PMID: 12006960.
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    184. Nield LE, Silverman ED, Taylor GP, Smallhorn JF, Mullen JB, Silverman NH, Finley JP, Law YM, Human DG, Seaward PG, Hamilton RM, Hornberger LK. Maternal anti-Ro and anti-La antibody-associated endocardial fibroelastosis. Circulation. 2002 Feb 19; 105(7):843-8. PMID: 11854125.
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    185. Brunner HI, Silverman ED, To T, Bombardier C, Feldman BM. Risk factors for damage in childhood-onset systemic lupus erythematosus: cumulative disease activity and medication use predict disease damage. Arthritis Rheum. 2002 Feb; 46(2):436-44. PMID: 11840446.
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    186. Gladman G, Silverman ED, Luy L, Boutin C, Laskin C, Smallhorn JF. Fetal echocardiographic screening of pregnancies of mothers with anti-Ro and/or anti-La antibodies. Am J Perinatol. 2002 Feb; 19(2):73-80. PMID: 11938480.
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    187. Jaeggi ET, Hamilton RM, Silverman ED, Zamora SA, Hornberger LK. Outcome of children with fetal, neonatal or childhood diagnosis of isolated congenital atrioventricular block. A single institution's experience of 30 years. J Am Coll Cardiol. 2002 Jan 02; 39(1):130-7. PMID: 11755298.
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    188. Gordon MM, Silverman ED, Kim JH, Huber AM, Furuya K. Acute severe hepatitis with coagulopathy: An unusual presentation of Kawasaki syndrome in association with Epstein-Barr virus. Paediatr Child Health. 2001 Nov; 6(9):627-30. PMID: 20084133.
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    189. Silva AA, Maeno Y, Hashmi A, Smallhorn JF, Silverman ED, McCrindle BW. Cardiovascular risk factors after Kawasaki disease: a case-control study. J Pediatr. 2001 Mar; 138(3):400-5. PMID: 11241050.
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    190. Tse S, Lubelsky S, Gordon M, Al Mayouf SM, Babyn PS, Laxer RM, Silverman ED, Schneider R, Feldman BM. The arthritis of inflammatory childhood myositis syndromes. J Rheumatol. 2001 Jan; 28(1):192-7. PMID: 11196524.
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    191. Spiegel LR, Schneider R, Lang BA, Birdi N, Silverman ED, Laxer RM, Stephens D, Feldman BM. Early predictors of poor functional outcome in systemic-onset juvenile rheumatoid arthritis: a multicenter cohort study. Arthritis Rheum. 2000 Nov; 43(11):2402-9. PMID: 11083261.
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    192. Al-Mayouf SM, Laxer RM, Schneider R, Silverman ED, Feldman BM. Intravenous immunoglobulin therapy for juvenile dermatomyositis: efficacy and safety. J Rheumatol. 2000 Oct; 27(10):2498-503. PMID: 11036850.
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    193. Han RK, Silverman ED, Newman A, McCrindle BW. Management and outcome of persistent or recurrent fever after initial intravenous gamma globulin therapy in acute Kawasaki disease. Arch Pediatr Adolesc Med. 2000 Jul; 154(7):694-9. PMID: 10891021.
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    194. Lawrence S, Luy L, Laxer R, Krafchik B, Silverman E. The health of mothers of children with cutaneous neonatal lupus erythematosus differs from that of mothers of children with congenital heart block. Am J Med. 2000 Jun 15; 108(9):705-9. PMID: 10924646.
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    195. Han RK, Sinclair B, Newman A, Silverman ED, Taylor GW, Walsh P, McCrindle BW. Recognition and management of Kawasaki disease. CMAJ. 2000 Mar 21; 162(6):807-12. PMID: 10750471.
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    196. Lovell DJ, Giannini EH, Reiff A, Cawkwell GD, Silverman ED, Nocton JJ, Stein LD, Gedalia A, Ilowite NT, Wallace CA, Whitmore J, Finck BK. Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group. N Engl J Med. 2000 Mar 16; 342(11):763-9. PMID: 10717011.
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    197. Brunner HI, Freedman M, Silverman ED. Close relationship between systemic lupus erythematosus and thrombotic thrombocytopenic purpura in childhood. Arthritis Rheum. 1999 Nov; 42(11):2346-55. PMID: 10555030.
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    198. Brunner HI, Feldman BM, Bombardier C, Silverman ED. Sensitivity of the Systemic Lupus Erythematosus Disease Activity Index, British Isles Lupus Assessment Group Index, and Systemic Lupus Activity Measure in the evaluation of clinical change in childhood-onset systemic lupus erythematosus. Arthritis Rheum. 1999 Jul; 42(7):1354-60. PMID: 10403262.
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    199. Tse S, Saunders EF, Silverman E, Vajsar J, Becker L, Meaney B. Myasthenia gravis and polymyositis as manifestations of chronic graft-versus-host-disease. Bone Marrow Transplant. 1999 Feb; 23(4):397-9. PMID: 10100585.
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    200. Barron KS, Shulman ST, Rowley A, Taubert K, Myones BL, Meissner HC, Peters J, Duffy CE, Silverman E, Sundel R. Report of the National Institutes of Health Workshop on Kawasaki Disease. J Rheumatol. 1999 Jan; 26(1):170-90. PMID: 9918260.
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    201. Menon A, Silverman ED, Gow RM, Hamilton RM. Chronotropic competence of the sinus node in congenital complete heart block. Am J Cardiol. 1998 Nov 01; 82(9):1119-21, A9. PMID: 9817493.
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    202. Berube C, Mitchell L, Silverman E, David M, Saint Cyr C, Laxer R, Adams M, Vegh P, Andrew M. The relationship of antiphospholipid antibodies to thromboembolic events in pediatric patients with systemic lupus erythematosus: a cross-sectional study. Pediatr Res. 1998 Sep; 44(3):351-6. PMID: 9727712.
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    203. D'Souza SJ, Tsai WS, Silver MM, Chait P, Benson LN, Silverman E, Hebért D, Balfe JW. Diagnosis and management of stenotic aorto-arteriopathy in childhood. J Pediatr. 1998 Jun; 132(6):1016-22. PMID: 9627596.
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    204. al-Mayouf SM, Silverman ED, Feldman BM, Thorner P, Laxer RM. Cyclosporine in the treatment of an unusual case of juvenile systemic sclerosis. J Rheumatol. 1998 Apr; 25(4):791-3. PMID: 9558187.
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    205. Uziel Y, Silverman ED. Intravenous immunoglobulin therapy in a child with cutaneous polyarteritis nodosa. Clin Exp Rheumatol. 1998 Mar-Apr; 16(2):187-9. PMID: 9536399.
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    206. Russo R, Gilday D, Laxer RM, Eddy A, Silverman ED. Single photon emission computed tomography scanning in childhood systemic lupus erythematosus. J Rheumatol. 1998 Mar; 25(3):576-82. PMID: 9517784.
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    207. Hamilton RM, Lee-Poy M, Kruger K, Silverman ED. Investigative methods of congenital complete heart block. J Electrocardiol. 1998; 30 Suppl:69-74. PMID: 9535483.
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    208. Gazarian M, Feldman BM, Benson LN, Gilday DL, Laxer RM, Silverman ED. Assessment of myocardial perfusion and function in childhood systemic lupus erythematosus. J Pediatr. 1998 Jan; 132(1):109-16. PMID: 9470010.
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    209. Schraml FV, Driver DR, Randolph T, Silverman ED. PET versus SPECT for determining myocardial tissue viability using fluorine-18-fluorodeoxyglucose. J Nucl Med Technol. 1997 Dec; 25(4):272-4. PMID: 9438929.
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    210. Uziel Y, Laxer RM, Silverman ED. Persistent pulmonary hemorrhage as the sole initial clinical manifestation of pediatric systemic lupus erythematosus. Clin Exp Rheumatol. 1997 Nov-Dec; 15(6):697-700. PMID: 9444430.
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    211. Silverman ED, Laxer RM. Neonatal lupus erythematosus. Rheum Dis Clin North Am. 1997 Aug; 23(3):599-618. PMID: 9287379.
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    212. Zhang H, Phang D, Laxer RM, Silverman ED, Pan S, Doherty PJ. Evolution of the T cell receptor beta repertoire from synovial fluid T cells of patients with juvenile onset rheumatoid arthritis. J Rheumatol. 1997 Jul; 24(7):1396-402. PMID: 9228144.
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    213. Wong M, Silverman ED, Fish EN. Evidence for RANTES, monocyte chemotactic protein-1, and macrophage inflammatory protein-1 beta expression in Kawasaki disease. J Rheumatol. 1997 Jun; 24(6):1179-85. PMID: 9195529.
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    214. al-Mayouf SM, Babyn P, Schneider R, Silverman ED, Laxer RM. Patellar enthesopathy in childhood: a new clinical and radiographic observation. J Rheumatol. 1997 Jun; 24(6):1186-8. PMID: 9195530.
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    215. Silverman ED, Lang B. An overview of the treatment of childhood SLE. Scand J Rheumatol. 1997; 26(4):241-6. PMID: 9310101.
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    216. Feldman BM, Reichlin M, Laxer RM, Targoff IN, Stein LD, Silverman ED. Clinical significance of specific autoantibodies in juvenile dermatomyositis. J Rheumatol. 1996 Oct; 23(10):1794-7. PMID: 8895161.
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    217. Feldman BM, Birdi N, Boone JE, Dent PB, Duffy CM, Ellsworth JE, Lang BA, Laxer RM, Lewkonia RM, Malleson PN, Oen KG, Paquin JD, Rosenberg AM, Schneider R, Silverman ED. Seasonal onset of systemic-onset juvenile rheumatoid arthritis. J Pediatr. 1996 Oct; 129(4):513-8. PMID: 8859257.
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    218. Silverman E. What's new in the treatment of pediatric SLE. J Rheumatol. 1996 Sep; 23(9):1657-60. PMID: 8877943.
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    219. Kruithoff WA, Schraml FV, Silverman ED. Tl-201 scintigraphy in multivessel exercise-induced variant angina. Clin Nucl Med. 1996 Sep; 21(9):675-8. PMID: 8879865.
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    220. Greenwald M, Couper R, Laxer R, Durie P, Silverman E. Gastroesophageal reflux and esophagitis-associated hypertrophic osteoarthropathy. J Pediatr Gastroenterol Nutr. 1996 Aug; 23(2):178-81. PMID: 8856586.
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    221. Doherty PJ, Inman RD, Laxer RM, Silverman ED, Yang SX, Suurmann I, Pan S. Analysis of T cell receptor gamma transcripts in right and left knee synovial fluids of patients with rheumatoid arthritis. J Rheumatol. 1996 Jul; 23(7):1143-50. PMID: 8823684.
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    222. Uziel Y, Laxer RM, Schneider R, Silverman ED. Intravenous immunoglobulin therapy in systemic onset juvenile rheumatoid arthritis: a followup study. J Rheumatol. 1996 May; 23(5):910-8. PMID: 8724308.
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    223. Giannini EH, Lovell DJ, Silverman ED, Sundel RP, Tague BL, Ruperto N. Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: a phase I/II study. Pediatric Rheumatology Collaborative Study Group. J Rheumatol. 1996 May; 23(5):919-24. PMID: 8724309.
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    224. Herman BE, Vargo JJ, Baum S, Silverman ED, Eisold J. Gastric antral vascular ectasia: a case report and review of the literature. J Nucl Med. 1996 May; 37(5):854-6. PMID: 8965161.
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    225. Muzaffer MA, Schneider R, Cameron BJ, Silverman ED, Laxer RM. Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis. J Pediatr. 1996 May; 128(5 Pt 1):698-700. PMID: 8627446.
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    226. Press J, Palayew K, Laxer RM, Elkon K, Eddy A, Rakoff D, Silverman ED. Antiribosomal P antibodies in pediatric patients with systemic lupus erythematosus and psychosis. Arthritis Rheum. 1996 Apr; 39(4):671-6. PMID: 8630119.
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    227. Press J, Uziel Y, Laxer RM, Luy L, Hamilton RM, Silverman ED. Long-term outcome of mothers of children with complete congenital heart block. Am J Med. 1996 Mar; 100(3):328-32. PMID: 8629679.
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    228. Pilkington C, Taylor PV, Silverman E, Isenberg DA, Costello AM, Rook GA. Agalactosyl IgG and materno-fetal transmission of autoimmune neonatal lupus. Rheumatol Int. 1996; 16(3):89-94. PMID: 8893372.
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    229. Rosenberg AM, Uziel Y, Krafchik BR, Hauta SA, Prokopchuk PA, Silverman ED, Laxer RM. Antinuclear antibodies in children with localized scleroderma. J Rheumatol. 1995 Dec; 22(12):2337-43. PMID: 8835572.
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    230. Gazarian M, Laxer RM, Kooh SW, Silverman ED. Hypoparathyroidism associated with systemic lupus erythematosus. J Rheumatol. 1995 Nov; 22(11):2156-8. PMID: 8596161.
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    231. Steinlin MI, Blaser SI, Gilday DL, Eddy AA, Logan WJ, Laxer RM, Silverman ED. Neurologic manifestations of pediatric systemic lupus erythematosus. Pediatr Neurol. 1995 Oct; 13(3):191-7. PMID: 8554655.
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    232. Dupuis LL, Koren G, Silverman ED, Laxer RM. Influence of food on the bioavailability of oral methotrexate in children. J Rheumatol. 1995 Aug; 22(8):1570-3. PMID: 7473485.
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    233. Press J, Berkovitch M, Laxer R, Giesbrecht E, Verjee Z, Silverman E, Klein J, Koren G. Evaluation of therapeutic drug monitoring of methotrexate in saliva of children with rheumatic diseases. Ther Drug Monit. 1995 Jun; 17(3):247-50. PMID: 7624920.
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    234. Silverman ED, Buyon J, Laxer RM, Hamilton R, Bini P, Chu JL, Elkon KB. Autoantibody response to the Ro/La particle may predict outcome in neonatal lupus erythematosus. Clin Exp Immunol. 1995 Jun; 100(3):499-505. PMID: 7774062.
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    235. Uziel Y, Laxer RM, Blaser S, Andrew M, Schneider R, Silverman ED. Cerebral vein thrombosis in childhood systemic lupus erythematosus. J Pediatr. 1995 May; 126(5 Pt 1):722-7. PMID: 7751995.
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    236. Gazarian M, Berkovitch M, Koren G, Silverman ED, Laxer RM. Experience with misoprostol therapy for NSAID gastropathy in children. Ann Rheum Dis. 1995 Apr; 54(4):277-80. PMID: 7763105.
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    237. Stamato T, Laxer RM, de Freitas C, Gow R, Silverman ED, Luy L, Smallhorn JF. Prevalence of cardiac manifestations of juvenile ankylosing spondylitis. Am J Cardiol. 1995 Apr 01; 75(10):744-6. PMID: 7900679.
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    238. Sheth AP, Esterly NB, Ratoosh SL, Smith JP, Hebert AA, Silverman E. U1RNP positive neonatal lupus erythematosus: association with anti-La antibodies? Br J Dermatol. 1995 Apr; 132(4):520-6. PMID: 7748740.
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    239. Eberhard BA, Andersson U, Laxer RM, Rose V, Silverman ED. Evaluation of the cytokine response in Kawasaki disease. Pediatr Infect Dis J. 1995 Mar; 14(3):199-203. PMID: 7539120.
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    240. Feldman BM, Ayling-Campos A, Luy L, Stevens D, Silverman ED, Laxer RM. Measuring disability in juvenile dermatomyositis: validity of the childhood health assessment questionnaire. J Rheumatol. 1995 Feb; 22(2):326-31. PMID: 7738957.
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    241. Lang BA, Schneider R, Reilly BJ, Silverman ED, Laxer RM. Radiologic features of systemic onset juvenile rheumatoid arthritis. J Rheumatol. 1995 Jan; 22(1):168-73. PMID: 7699666.
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    242. Silverman ED, Cawkwell GD, Lovell DJ, Laxer RM, Lehman TJ, Passo MH, Zemel LS, Giannini EH. Intravenous immunoglobulin in the treatment of systemic juvenile rheumatoid arthritis: a randomized placebo controlled trial. Pediatric Rheumatology Collaborative Study Group. J Rheumatol. 1994 Dec; 21(12):2353-8. PMID: 7699642.
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    243. Pruzanski W, Albin-Cook K, Laxer RM, MacMillan J, Stefanski E, Vadas P, Silverman ED. Phospholipase A2 in juvenile rheumatoid arthritis: correlation to disease type and activity. J Rheumatol. 1994 Oct; 21(10):1951-4. PMID: 7837165.
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    244. Shabib S, Laxer R, Silverman E, Perez-Perez G, Blaser M, Sherman P. Seroprevalence of Helicobacter pylori infection is not increased in pediatric inflammatory arthritides. J Rheumatol. 1994 Aug; 21(8):1548-52. PMID: 7983663.
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    245. Eberhard A, Sparling C, Sudbury S, Ford P, Laxer R, Silverman E. Hypoprothrombinemia in childhood systemic lupus erythematosus. Semin Arthritis Rheum. 1994 Aug; 24(1):12-8. PMID: 7985033.
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    246. Uziel Y, Krafchik BR, Feldman B, Silverman ED, Rubin LA, Laxer RM. Serum levels of soluble interleukin-2 receptor. A marker of disease activity in localized scleroderma. Arthritis Rheum. 1994 Jun; 37(6):898-901. PMID: 8003062.
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    247. Eberhard BA, Laxer RM, Andersson U, Silverman ED. Local synthesis of both macrophage and T cell cytokines by synovial fluid cells from children with juvenile rheumatoid arthritis. Clin Exp Immunol. 1994 May; 96(2):260-6. PMID: 8187333.
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    248. Uziel Y, Krafchik BR, Silverman ED, Thorner PS, Laxer RM. Localized scleroderma in childhood: a report of 30 cases. Semin Arthritis Rheum. 1994 Apr; 23(5):328-40. PMID: 8036522.
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    249. Plioplys AV, Greaves A, Kazemi K, Silverman E. Lymphocyte function in autism and Rett syndrome. Neuropsychobiology. 1994; 29(1):12-6. PMID: 8127418.
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    250. Bargman JM, Nong Y, Silverman ED. The effect of in vivo erythropoietin on cytokine mRNA in CAPD patients. Adv Perit Dial. 1994; 10:129-34. PMID: 7999810.
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    251. Liu P, Uziel Y, Chuang S, Silverman E, Krafchik B, Laxer R. Localized scleroderma: imaging features. Pediatr Radiol. 1994; 24(3):207-9. PMID: 7936801.
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    252. Rosh JR, Silverman ED, Groisman G, Dolgin S, LeLeiko NS. Intrahepatic cholestasis in neonatal lupus erythematosus. J Pediatr Gastroenterol Nutr. 1993 Oct; 17(3):310-2. PMID: 8271133.
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    253. Isacovics B, Silverman ED. Limiting dilution analysis of Epstein-Barr virus infectable B cells secreting anti-Ro/SSA and anti-La/SSB antibodies in neonatal lupus erythematosus and systemic lupus erythematosus. J Autoimmun. 1993 Aug; 6(4):481-94. PMID: 8216690.
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    254. Feldman BM, Zabriskie JB, Silverman ED, Laxer RM. Diagnostic use of B-cell alloantigen D8/17 in rheumatic chorea. J Pediatr. 1993 Jul; 123(1):84-6. PMID: 8320631.
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    255. Silverman ED. Congenital heart block and neonatal lupus erythematosus: prevention is the goal. J Rheumatol. 1993 Jul; 20(7):1101-4. PMID: 8371199.
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    256. Taylor DB, Babyn P, Blaser S, Smith S, Shore A, Silverman ED, Chuang S, Laxer RM. MR evaluation of the temporomandibular joint in juvenile rheumatoid arthritis. J Comput Assist Tomogr. 1993 May-Jun; 17(3):449-54. PMID: 8491910.
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    257. Lang BA, Silverman ED. A clinical overview of systemic lupus erythematosus in childhood. Pediatr Rev. 1993 May; 14(5):194-201. PMID: 8493191.
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    258. Barron KS, Silverman ED, Gonzales J, Reveille JD. Clinical, serologic, and immunogenetic studies in childhood-onset systemic lupus erythematosus. Arthritis Rheum. 1993 Mar; 36(3):348-54. PMID: 8452580.
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    259. Birdi N, Laxer RM, Thorner P, Fritzler MJ, Silverman ED. Localized scleroderma progressing to systemic disease. Case report and review of the literature. Arthritis Rheum. 1993 Mar; 36(3):410-5. PMID: 8452586.
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    260. Silverman ED, Isacovics B, Petsche D, Laxer RM. Synovial fluid cells in juvenile arthritis: evidence of selective T cell migration to inflamed tissue. Clin Exp Immunol. 1993 Jan; 91(1):90-5. PMID: 8093436.
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    261. Barron KS, Silverman ED, Gonzales JC, St Clair M, Anderson K, Reveille JD. Major histocompatibility complex class II alleles in Kawasaki syndrome--lack of consistent correlation with disease or cardiac involvement. J Rheumatol. 1992 Nov; 19(11):1790-3. PMID: 1491403.
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    262. Barron KS, Silverman ED, Gonzales JC, Owerbach D, Reveille JD. DNA analysis of HLA-DR, DQ, and DP alleles in children with polyarticular juvenile rheumatoid arthritis. J Rheumatol. 1992 Oct; 19(10):1611-6. PMID: 1361203.
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    263. Padeh S, Laxer RM, Gleich GJ, Armstrong PF, Silverman ED. High synovial immunoglobulin E levels in eosinophilic synovitis. J Pediatr. 1992 Sep; 121(3):417-9. PMID: 1517920.
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    264. Doherty PJ, Yang SX, Laxer RM, Silverman ED, Inman R, Pan S. Evidence for clonal expansion of T cell receptor V gamma II+ T cells in the synovial fluid of patients with arthritis. J Immunol. 1992 Jul 01; 149(1):295-9. PMID: 1318903.
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    265. Eberhard A, Couper R, Durie P, Silverman E. Exocrine pancreatic function in children with systemic lupus erythematosus. J Rheumatol. 1992 Jun; 19(6):964-7. PMID: 1404136.
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    266. Birdi N, Shore A, Rush P, Laxer RM, Silverman ED, Krafchik B. Childhood linear scleroderma: a possible role of thermography for evaluation. J Rheumatol. 1992 Jun; 19(6):968-73. PMID: 1404137.
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    267. Barron KS, Sher MR, Silverman ED. Intravenous immunoglobulin therapy: magic or black magic. J Rheumatol Suppl. 1992 Apr; 33:94-7. PMID: 1593608.
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    268. Doherty PJ, Silverman ED, Laxer RM, Yang SX, Pan S. T cell receptor V beta usage in synovial fluid of children with arthritis. J Rheumatol. 1992 Mar; 19(3):463-8. PMID: 1533679.
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    269. Schneider R, Lang BA, Reilly BJ, Laxer RM, Silverman ED, Ibanez D, Bombardier C, Roifman CM. Prognostic indicators of joint destruction in systemic-onset juvenile rheumatoid arthritis. J Pediatr. 1992 Feb; 120(2 Pt 1):200-5. PMID: 1735815.
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    270. Padeh S, Laxer RM, Silver MM, Silverman ED. Primary pulmonary hypertension in a patient with systemic-onset juvenile arthritis. Arthritis Rheum. 1991 Dec; 34(12):1575-9. PMID: 1747143.
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    271. Silverman ED, Laxer RM, Nelson DL, Rubin LA. Soluble interleukin-2 receptor in juvenile rheumatoid arthritis. J Rheumatol. 1991 Sep; 18(9):1398-402. PMID: 1757944.
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    272. Lang BA, Laxer RM, Murphy G, Silverman ED, Roifman CM. Treatment of dermatomyositis with intravenous gammaglobulin. Am J Med. 1991 Aug; 91(2):169-72. PMID: 1714236.
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    273. Eberhard BA, Laxer RM, Eddy AA, Silverman ED. Presence of thyroid abnormalities in children with systemic lupus erythematosus. J Pediatr. 1991 Aug; 119(2):277-9. PMID: 1861215.
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    274. Feldman BM, Silverman ED. Methotrexate therapy for juvenile rheumatoid arthritis. J Pediatr. 1991 Jun; 118(6):992-3. PMID: 2040940.
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    275. Eberhard A, Shore A, Silverman E, Laxer R. Bowel perforation and interstitial cystitis in childhood systemic lupus erythematosus. J Rheumatol. 1991 May; 18(5):746-7. PMID: 1865424.
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    276. Koren G, Silverman E, Sundel R, Edney P, Newburger JW, Klein J, Robieux I, Laxer R, Giesbrecht E, Burns JC. Decreased protein binding of salicylates in Kawasaki disease. J Pediatr. 1991 Mar; 118(3):456-9. PMID: 1999792.
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    277. Byard RW, Edmonds JF, Silverman E, Silver MM. Respiratory distress and fever in a 2-month-old infant. J Pediatr. 1991 Feb; 118(2):306-13. PMID: 1993966.
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    278. Silverman E, Mamula M, Hardin JA, Laxer R. Importance of the immune response to the Ro/La particle in the development of congenital heart block and neonatal lupus erythematosus. J Rheumatol. 1991 Jan; 18(1):120-4. PMID: 2023181.
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    279. Dupuis LL, Koren G, Shore A, Silverman ED, Laxer RM. Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis. J Rheumatol. 1990 Nov; 17(11):1469-73. PMID: 2273487.
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    280. Barron KS, Murphy DJ, Silverman ED, Ruttenberg HD, Wright GB, Franklin W, Goldberg SJ, Higashino SM, Cox DG, Lee M. Treatment of Kawasaki syndrome: a comparison of two dosage regimens of intravenously administered immune globulin. J Pediatr. 1990 Oct; 117(4):638-44. PMID: 2213395.
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    281. Hamilton ML, Gladman DD, Shore A, Laxer RM, Silverman ED. Juvenile psoriatic arthritis and HLA antigens. Ann Rheum Dis. 1990 Sep; 49(9):694-7. PMID: 2241285.
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    282. Silverman ED, Laxer RM, Greenwald M, Gelfand E, Shore A, Stein LD, Roifman CM. Intravenous gamma globulin therapy in systemic juvenile rheumatoid arthritis. Arthritis Rheum. 1990 Jul; 33(7):1015-22. PMID: 1695098.
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    283. Lang BA, Silverman ED, Laxer RM, Rose V, Nelson DL, Rubin LA. Serum-soluble interleukin-2 receptor levels in Kawasaki disease. J Pediatr. 1990 Apr; 116(4):592-6. PMID: 2319407.
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    284. Lang BA, Laxer RM, Thorner P, Greenberg M, Silverman ED. Pediatric onset of Behçet's syndrome with myositis: case report and literature review illustrating unusual features. Arthritis Rheum. 1990 Mar; 33(3):418-25. PMID: 2180406.
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    285. Laxer RM, Roberts EA, Gross KR, Britton JR, Cutz E, Dimmick J, Petty RE, Silverman ED. Liver disease in neonatal lupus erythematosus. J Pediatr. 1990 Feb; 116(2):238-42. PMID: 2299493.
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    286. Silverman ED, Somma C, Khan MM, Melmon KL, Engleman EG. Abnormal T suppressor cell function in juvenile rheumatoid arthritis. Arthritis Rheum. 1990 Feb; 33(2):205-11. PMID: 2154996.
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    287. Lang BA, Silverman ED, Laxer RM, Lau AS. Spontaneous tumor necrosis factor production in Kawasaki disease. J Pediatr. 1989 Dec; 115(6):939-43. PMID: 2585231.
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    288. Mamula MJ, Silverman ED, Laxer RM, Bentur L, Isacovics B, Hardin JA. Human monoclonal anti-La antibodies. The La protein resides on a subset of Ro particles. J Immunol. 1989 Nov 01; 143(9):2923-8. PMID: 2478628.
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    289. Lehman TJ, Reichlin M, Santner TJ, Silverman E, Petty RE, Spencer CH, Harley JB. Maternal antibodies to Ro (SS-A) are associated with both early onset of disease and male sex among children with systemic lupus erythematosus. Arthritis Rheum. 1989 Nov; 32(11):1414-20. PMID: 2818658.
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    290. Duffy CM, Laxer RM, Silverman ED. Drug therapy for juvenile arthritis. Compr Ther. 1989 Oct; 15(10):48-59. PMID: 2572375.
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    291. Pauls JD, Silverman E, Laxer RM, Fritzler MJ. Antibodies to histones H1 and H5 in sera of patients with juvenile rheumatoid arthritis. Arthritis Rheum. 1989 Jul; 32(7):877-83. PMID: 2787640.
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    292. Duffy CM, Laxer RM, Lee P, Ramsay C, Fritzler M, Silverman ED. Raynaud syndrome in childhood. J Pediatr. 1989 Jan; 114(1):73-8. PMID: 2783344.
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    293. Bargman JM, Silverman ED, Klein MH. Effect of 1,25-dihydroxyvitamin D3 in vivo on circulating T lymphocytes. Miner Electrolyte Metab. 1989; 15(6):359-64. PMID: 2615722.
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    294. Laxer RM, Shore AD, Manson D, King S, Silverman ED, Wilmot DM. Chronic recurrent multifocal osteomyelitis and psoriasis--a report of a new association and review of related disorders. Semin Arthritis Rheum. 1988 May; 17(4):260-70. PMID: 2976529.
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    295. Koren G, Schaffer F, Silverman E, Walker S, Duffy C, Stein L, Suria D, Schue S, Thiessen JJ, Gelfand E, et al. Determinants of low serum concentrations of salicylates in patients with Kawasaki disease. J Pediatr. 1988 Apr; 112(4):663-7. PMID: 3351695.
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    296. Bennett AE, Silverman ED, Miller JJ, Hintz RL. Insulin-like growth factors I and II in children with systemic onset juvenile arthritis. J Rheumatol. 1988 Apr; 15(4):655-8. PMID: 3397975.
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    297. Laxer RM, Cameron BJ, Silverman ED. Occurrence of Kawasaki disease and systemic lupus erythematosus in a single patient. J Rheumatol. 1988 Mar; 15(3):515-6. PMID: 3379628.
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    298. Laxer RM, Silverman ED, St-Cyr C, Tran MT, Lingam G. A six-month open safety assessment of a naproxen suspension formulation in the therapy of juvenile rheumatoid arthritis. Clin Ther. 1988; 10(4):381-7. PMID: 3079006.
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    299. Laxer RM, Silverman ED, Balfe JW, Poucell S, Baumal R. Naproxen-associated renal failure in a child with arthritis and inflammatory bowel disease. Pediatrics. 1987 Dec; 80(6):904-8. PMID: 3684403.
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    300. Silverman ED, Smith RL, Schurman DJ, Miller JJ. Spontaneous secretion of a proteoglycan releasing factor by mononuclear cells in juvenile arthritis. J Rheumatol. 1987 Jun; 14(3):540-7. PMID: 3498038.
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    301. Drane WE, Karvelis K, Johnson DA, Curran JJ, Silverman ED. Scintigraphic detection of metoclopramide esophageal stimulation in progressive systemic sclerosis. J Nucl Med. 1987 May; 28(5):810-5. PMID: 3572543.
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    302. Laxer RM, Schaffer FM, Myones BL, Yount WJ, Rowe RD, Rubin L, Stein LD, Gelfand EW, Silverman ED. Lymphocyte abnormalities and complement activation in Kawasaki disease. Prog Clin Biol Res. 1987; 250:175-84. PMID: 3423037.
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    303. Miller JJ, Olds LC, Silverman ED, Milgrom H, Curd JG. Different patterns of C3 and C4 activation in the varied types of juvenile arthritis. Pediatr Res. 1986 Dec; 20(12):1332-7. PMID: 3099253.
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    304. Kaufman DB, Laxer RM, Silverman ED, Stein L. Systemic lupus erythematosus in childhood and adolescence--the problem, epidemiology, incidence, susceptibility, genetics, and prognosis. Curr Probl Pediatr. 1986 Oct; 16(10):545-625. PMID: 3780292.
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    305. Drane WE, Karvelis K, Johnson DA, Curran JJ, Silverman ED. Progressive systemic sclerosis: radionuclide esophageal scintigraphy and manometry. Radiology. 1986 Jul; 160(1):73-6. PMID: 3715047.
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    306. Khan MM, Sansoni P, Silverman ED, Engleman EG, Melmon KL. Beta-adrenergic receptors on human suppressor, helper, and cytolytic lymphocytes. Biochem Pharmacol. 1986 Apr 01; 35(7):1137-42. PMID: 3008755.
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    307. Silverman ED, Adornato BT, Miller JJ. Eosinophilic fasciitis in a two-year-old child. Arthritis Rheum. 1985 Aug; 28(8):948-51. PMID: 4026891.
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    308. Somma C, Miller JJ, Silverman ED, Link MP. Abnormal helper:suppressor T-cell ratio in the staff of a pediatric hospital. N Engl J Med. 1985 Jun 13; 312(24):1573-4. PMID: 3158815.
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    309. Myones BL, Silverman ED, Miller JJ. Children with rheumatic diseases and the effects of steroid pulses on T cells. Arthritis Rheum. 1985 Apr; 28(4):477. PMID: 3872666.
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    310. Sansoni P, Silverman ED, Khan MM, Melmon KL, Engleman EG. Immunoregulatory T cells in man. Histamine-induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T cells. J Clin Invest. 1985 Feb; 75(2):650-6. PMID: 3156150.
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    311. Khan MM, Silverman E, Engleman EG, Melmon KL. Responses of subpopulations of human helper T cells to autacoids. Proc West Pharmacol Soc. 1985; 28:225-8. PMID: 2866535.
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    312. Silverman ED, Smith RL, Schurman DJ, Miller JJ. The effect of juvenile inflammatory synovial fluid on in vitro cartilage. J Rheumatol. 1984 Dec; 11(6):798-803. PMID: 6520835.
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    313. Silverman ED, Myones BL, Miller JJ. Lymphocyte subpopulation alterations induced by intravenous megadose pulse methylprednisolone. J Rheumatol. 1984 Jun; 11(3):287-90. PMID: 6234390.
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    314. Silverman ED, Miller JJ, Bernstein B, Shafai T. Consumption coagulopathy associated with systemic juvenile rheumatoid arthritis. J Pediatr. 1983 Dec; 103(6):872-6. PMID: 6644421.
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    315. Silverman E, Bargman J. Combined neutrophil and T-cell deficiency. Am J Med. 1983 Aug; 75(2):216, 232. PMID: 6603792.
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    316. Hanna W, Silverman E, Boxall L, Krafchik BR. Ultrastructural features of epidermolysis bullosa. Ultrastruct Pathol. 1983 Jul; 5(1):29-36. PMID: 6649087.
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