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Charles Deber

TitleSenior Scientist
InstitutionThe Hospital for Sick Children
DepartmentMolecular Medicine
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Biography 
    Collapse education and training
    Massachusetts Institute of Technology (MIT), Cambridge, MAPhD.1967Organic Chemistry
    Polytechnic Institute of Brooklyn, Brooklyn, NYBSc.1962Chemistry
    Collapse awards and honors
    2017Bruce Merrifield Award for “Outstanding Lifetime Accomplishment in Peptide Research", American Peptide Society
    2009Murray Goodman Award for Scientific Excellence and Mentorship in Peptide Science
    2001Fellow of the Royal Society of Canada (FRSC), The Royal Society of Canada
    2001Canadian Who's Who
    2000Vincent du Vigneaud Award for Outstanding Achievements in Peptide Research, American Peptide Society
    1996W.T. Aikins Award for Excellence in Undergraduate Teaching, University of Toronto, Faculty of Medicine
    1970Who's Who in the East
    1962Phi Lambda Upsilon (Chemistry Honorary)

    Collapse Overview 
    Collapse overview
    Charles Deber was born and raised in Brooklyn, New York. He received his B.Sc. from the Polytechnic Institute of Brooklyn (working with Murray Goodman); his PhD in Organic Chemistry from MIT (Arthur Cope); and was a post-doctoral fellow at Harvard Medical School (Elkan Blout) and research associate at the University of Wisconsin-Madison Enzyme Institute (Henry Lardy). He joined the Research Institute at The Hospital for Sick Children in 1976, with cross-appointment to the University of Toronto Department of Biochemistry.

    Dr. Deber was recognized by the American Peptide Society with the Vincent du Vigneaud Award in 2000 for “Outstanding Career Achievements in Peptide Research,” and the Murray Goodman Scientific Excellence and Mentorship Award in 2009. At U of T, he received the W.T. Aikins Award for excellence in undergraduate teaching in the Faculty of Medicine. Dr. Deber was elected in 2001 as a Fellow of the Royal Society of Canada (FRSC).

    Dr. Deber’s research utilizes natural and de novo designed hydrophobic peptides and proteins, and the application of spectroscopic techniques, molecular modeling, and bioinformatics, to investigate the interactions and structures of peptides and proteins within membranes, how membrane-embedded mutations underlie protein misfolding diseases, and how knowledge gained from these studies can be applied to the development of membrane-interactive peptide therapeutics.


    Collapse Research 
    Collapse research activities and funding
         (Charles Deber)Apr 1, 2016 - Mar 31, 2021
    Natural Sciences and Engineering Research Council of Canada (NSERC) - Discovery Grant
    Conformational Transitions of Membrane-Spanning Peptides

         (Charles Deber)Nov 1, 2016 - Oct 31, 2018
    Cystic Fibrosis Foundation (US) - Pilot Project Grant
    Novel Therapeutics for Treatment of Infections in Cystic Fibrosis

         (Charles Deber)Mar 1, 2017 - Feb 28, 2018
    The Hospital for Sick Children - Proof-of-Principle Grant
    Development of novel cationic antimicrobial peptides against bacterial biofilms

         (Charles Deber)Apr 1, 2017 - Mar 31, 2020
    Cystic Fibrosis Canada (CFC) - Research Grant
    Molecular basis of CF-causing mutations in CFTR

         (Charles Deber)Apr 1, 2017 - Mar 31, 2022
    Canadian Institutes of Health Research (CIHR) - Project Grant
    Peptide-based inhibitors of bacterial drug efflux pumps

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Beaudoin T, Stone TA, Glibowicka M, Adams C, Yau Y, Ahmadi S, Bear CE, Grasemann H, Waters V, Deber CM. Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms. Sci Rep. 2018 Oct 03; 8(1):14728. PMID: 30283025.
      View in: PubMed
    2. Krainer G, Treff A, Hartmann A, Stone TA, Schenkel M, Keller S, Deber CM, Schlierf M. A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTR. Commun Biol. 2018; 1:154. PMID: 30302398.
      View in: PubMed
    3. Ovchinnikov V, Stone TA, Deber CM, Karplus M. Structure of the EmrE multidrug transporter and its use for inhibitor peptide design. Proc Natl Acad Sci U S A. 2018 08 21; 115(34):E7932-E7941. PMID: 30082384.
      View in: PubMed
    4. Garton M, Nim S, Stone TA, Wang KE, Deber CM, Kim PM. Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1505-1510. PMID: 29378946.
      View in: PubMed
    5. Chang YH, Stone TA, Chin S, Glibowicka M, Bear CE, Deber CM. Structural effects of extracellular loop mutations in CFTR helical hairpins. Biochim Biophys Acta Biomembr. 2018 May; 1860(5):1092-1098. PMID: 29307731.
      View in: PubMed
    6. Stone TA, Cole GB, Nguyen HQ, Sharpe S, Deber CM. Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides. Bioorg Med Chem. 2018 03 15; 26(6):1189-1196. PMID: 29275987.
      View in: PubMed
    7. Stone TA, Schiller N, Workewych N, von Heijne G, Deber CM. Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo. Biochemistry. 2016 Oct 11; 55(40):5772-5779. PMID: 27620701.
      View in: PubMed
    8. Stone TA, Deber CM. Therapeutic design of peptide modulators of protein-protein interactions in membranes. Biochim Biophys Acta Biomembr. 2017 Apr; 1859(4):577-585. PMID: 27580024.
      View in: PubMed
    9. Ng DP, Deber CM. Modulating Transmembrane a-Helix Interactions through pH-Sensitive Boundary Residues. Biochemistry. 2016 08 09; 55(31):4306-15. PMID: 27434090.
      View in: PubMed
    10. Nadeau VG, Deber CM. Structural impact of proline mutations in the loop region of an ancestral membrane protein. Biopolymers. 2016 Jan; 106(1):37-42. PMID: 26566586.
      View in: PubMed
    11. Nadeau VG, Gao A, Deber CM. Design and characterization of a membrane protein unfolding platform in lipid bilayers. PLoS One. 2015; 10(3):e0120253. PMID: 25799099.
      View in: PubMed
    12. Deber CM, Ng DP. Helix-helix interactions: is the medium the message? Structure. 2015 Mar 03; 23(3):437-438. PMID: 25738383.
      View in: PubMed
    13. Stone TA, Schiller N, von Heijne G, Deber CM. Hydrophobic blocks facilitate lipid compatibility and translocon recognition of transmembrane protein sequences. Biochemistry. 2015 Feb 24; 54(7):1465-73. PMID: 25635746.
      View in: PubMed
    14. Bellmann-Sickert K, Stone TA, Poulsen BE, Deber CM. Efflux by small multidrug resistance proteins is inhibited by membrane-interactive helix-stapled peptides. J Biol Chem. 2015 Jan 16; 290(3):1752-9. PMID: 25425644.
      View in: PubMed
    15. Wang J, Rath A, Deber CM. Functional response of the small multidrug resistance protein EmrE to mutations in transmembrane helix 2. FEBS Lett. 2014 Oct 16; 588(20):3720-5. PMID: 25157436.
      View in: PubMed
    16. Ng DP, Deber CM. Terminal residue hydrophobicity modulates transmembrane helix-helix interactions. Biochemistry. 2014 Jun 17; 53(23):3747-57. PMID: 24857611.
      View in: PubMed
    17. Rath A, Cunningham F, Deber CM. Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts. Proc Natl Acad Sci U S A. 2013 Sep 24; 110(39):15668-73. PMID: 24019476.
      View in: PubMed
    18. Strandberg LS, Cui X, Rath A, Liu J, Silverman ED, Liu X, Siragam V, Ackerley C, Su BB, Yan JY, Capecchi M, Biavati L, Accorroni A, Yuen W, Quattrone F, Lung K, Jaeggi ET, Backx PH, Deber CM, Hamilton RM. Congenital heart block maternal sera autoantibodies target an extracellular epitope on the a1G T-type calcium channel in human fetal hearts. PLoS One. 2013; 8(9):e72668. PMID: 24039792.
      View in: PubMed
    19. Patel PC, Lee HS, Ming AY, Rath A, Deber CM, Yip CM, Rocheleau JV, Gray-Owen SD. Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties. J Biol Chem. 2013 Oct 11; 288(41):29654-69. PMID: 24005674.
      View in: PubMed
    20. Yin LM, Lee S, Mak JS, Helmy AS, Deber CM. Differential binding of L- vs. D-isomers of cationic antimicrobial peptides to the biofilm exopolysaccharide alginate. Protein Pept Lett. 2013 Aug; 20(8):843-7. PMID: 23458077.
      View in: PubMed
    21. Nadeau VG, Deber CM. Loop sequence dictates the secondary structure of a human membrane protein hairpin. Biochemistry. 2013 Apr 09; 52(14):2419-26. PMID: 23488803.
      View in: PubMed
    22. Rath A, Deber CM. Design of transmembrane peptides: coping with sticky situations. Methods Mol Biol. 2013; 1063:197-210. PMID: 23975779.
      View in: PubMed
    23. Rath A, Deber CM. Correction factors for membrane protein molecular weight readouts on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem. 2013 Mar 01; 434(1):67-72. PMID: 23201391.
      View in: PubMed
    24. Alvares RD, Tulumello DV, Macdonald PM, Deber CM, Prosser RS. Effects of a polar amino acid substitution on helix formation and aggregate size along the detergent-induced peptide folding pathway. Biochim Biophys Acta. 2013 Feb; 1828(2):373-81. PMID: 23031573.
      View in: PubMed
    25. Nadeau VG, Rath A, Deber CM. Sequence hydropathy dominates membrane protein response to detergent solubilization. Biochemistry. 2012 Aug 07; 51(31):6228-37. PMID: 22779403.
      View in: PubMed
    26. Poulsen BE, Deber CM. Drug efflux by a small multidrug resistance protein is inhibited by a transmembrane peptide. Antimicrob Agents Chemother. 2012 Jul; 56(7):3911-6. PMID: 22526304.
      View in: PubMed
    27. Rotstein BH, Winternheimer DJ, Yin LM, Deber CM, Yudin AK. Thioester-isocyanides: versatile reagents for the synthesis of cycle-tail peptides. Chem Commun (Camb). 2012 Apr 18; 48(31):3775-7. PMID: 22430393.
      View in: PubMed
    28. Tulumello DV, Deber CM. Efficiency of detergents at maintaining membrane protein structures in their biologically relevant forms. Biochim Biophys Acta. 2012 May; 1818(5):1351-8. PMID: 22285740.
      View in: PubMed
    29. Yin LM, Edwards MA, Li J, Yip CM, Deber CM. Roles of hydrophobicity and charge distribution of cationic antimicrobial peptides in peptide-membrane interactions. J Biol Chem. 2012 Mar 02; 287(10):7738-45. PMID: 22253439.
      View in: PubMed
    30. Rath A, Deber CM. Protein structure in membrane domains. Annu Rev Biophys. 2012; 41:135-55. PMID: 22577820.
      View in: PubMed
    31. Tulumello DV, Johnson RM, Isupov I, Deber CM. Design, expression, and purification of de novo transmembrane "hairpin" peptides. Biopolymers. 2012; 98(6):546-56. PMID: 23203760.
      View in: PubMed
    32. Mulvihill CM, Deber CM. Structural basis for misfolding at a disease phenotypic position in CFTR: comparison of TM3/4 helix-loop-helix constructs with TM4 peptides. Biochim Biophys Acta. 2012 Jan; 1818(1):49-54. PMID: 21996038.
      View in: PubMed
    33. Poulsen BE, Cunningham F, Lee KK, Deber CM. Modulation of substrate efflux in bacterial small multidrug resistance proteins by mutations at the dimer interface. J Bacteriol. 2011 Nov; 193(21):5929-35. PMID: 21890698.
      View in: PubMed
    34. Ng DP, Poulsen BE, Deber CM. Membrane protein misassembly in disease. Biochim Biophys Acta. 2012 Apr; 1818(4):1115-22. PMID: 21840297.
      View in: PubMed
    35. Tulumello DV, Deber CM. Positions of polar amino acids alter interactions between transmembrane segments and detergents. Biochemistry. 2011 May 17; 50(19):3928-35. PMID: 21473646.
      View in: PubMed
    36. Nørholm MH, Cunningham F, Deber CM, von Heijne G. Converting a marginally hydrophobic soluble protein into a membrane protein. J Mol Biol. 2011 Mar 18; 407(1):171-9. PMID: 21262233.
      View in: PubMed
    37. Cunningham F, Poulsen BE, Ip W, Deber CM. Beta-branched residues adjacent to GG4 motifs promote the efficient association of glycophorin A transmembrane helices. Biopolymers. 2011; 96(3):340-7. PMID: 21072853.
      View in: PubMed
    38. Rath A, Nadeau VG, Poulsen BE, Ng DP, Deber CM. Novel hydrophobic standards for membrane protein molecular weight determinations via sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry. 2010 Dec 21; 49(50):10589-91. PMID: 21105732.
      View in: PubMed
    39. Ng DP, Deber CM. Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs. Biochemistry. 2010 Aug 17; 49(32):6896-902. PMID: 20695528.
      View in: PubMed
    40. Mulvihill CM, Deber CM. Evidence that the translocon may function as a hydropathy partitioning filter. Biochim Biophys Acta. 2010 Oct; 1798(10):1995-8. PMID: 20646997.
      View in: PubMed
    41. Ng DP, Deber CM. Deletion of a terminal residue disrupts oligomerization of a transmembrane alpha-helix. Biochem Cell Biol. 2010 Apr; 88(2):339-45. PMID: 20453934.
      View in: PubMed
    42. Tulumello DV, Deber CM. SDS micelles as a membrane-mimetic environment for transmembrane segments. Biochemistry. 2009 Dec 29; 48(51):12096-103. PMID: 19921933.
      View in: PubMed
    43. Grant CV, Yang Y, Glibowicka M, Wu CH, Park SH, Deber CM, Opella SJ. A Modified Alderman-Grant Coil makes possible an efficient cross-coil probe for high field solid-state NMR of lossy biological samples. J Magn Reson. 2009 Nov; 201(1):87-92. PMID: 19733108.
      View in: PubMed
    44. Kim Chiaw P, Huan LJ, Gagnon S, Ly D, Sweezey N, Rotin D, Deber CM, Bear CE. Functional rescue of DeltaF508-CFTR by peptides designed to mimic sorting motifs. Chem Biol. 2009 May 29; 16(5):520-30. PMID: 19477416.
      View in: PubMed
    45. Rath A, Tulumello DV, Deber CM. Peptide models of membrane protein folding. Biochemistry. 2009 Apr 14; 48(14):3036-45. PMID: 19278229.
      View in: PubMed
    46. Cheung JC, Kim Chiaw P, Deber CM, Bear CE. A novel method for monitoring the cytosolic delivery of peptide cargo. J Control Release. 2009 Jul 01; 137(1):2-7. PMID: 19285529.
      View in: PubMed
    47. Poulsen BE, Rath A, Deber CM. The assembly motif of a bacterial small multidrug resistance protein. J Biol Chem. 2009 Apr 10; 284(15):9870-5. PMID: 19224913.
      View in: PubMed
    48. Rath A, Glibowicka M, Nadeau VG, Chen G, Deber CM. Detergent binding explains anomalous SDS-PAGE migration of membrane proteins. Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6):1760-5. PMID: 19181854.
      View in: PubMed
    49. Cunningham F, Rath A, Deber CM. Hydrophobic peptide segments in soluble proteins competent for membrane insertion: role in amyloidogenesis. Adv Exp Med Biol. 2009; 611:299-300. PMID: 19400201.
      View in: PubMed
    50. Cunningham F, Rath A, Johnson RM, Deber CM. Distinctions between hydrophobic helices in globular proteins and transmembrane segments as factors in protein sorting. J Biol Chem. 2009 Feb 20; 284(8):5395-402. PMID: 19095650.
      View in: PubMed
    51. Gierasch LM, Deber CM, Brodsky B. Celebrating the scientific legacy of Elkan R. Blout. Biopolymers. 2008 May; 89(5):323. PMID: 18307218.
      View in: PubMed
    52. Glukhov E, Burrows LL, Deber CM. Membrane interactions of designed cationic antimicrobial peptides: the two thresholds. Biopolymers. 2008 May; 89(5):360-71. PMID: 18186149.
      View in: PubMed
    53. Rath A, Deber CM. Surface recognition elements of membrane protein oligomerization. Proteins. 2008 Feb 15; 70(3):786-93. PMID: 17729275.
      View in: PubMed
    54. Cheung JC, Deber CM. Misfolding of the cystic fibrosis transmembrane conductance regulator and disease. Biochemistry. 2008 Feb 12; 47(6):1465-73. PMID: 18193900.
      View in: PubMed
    55. Deber CM, Cheung JC, Rath A. Defining the defect in F508 del CFTR: a soluble problem? Chem Biol. 2008 Jan; 15(1):3-4. PMID: 18215767.
      View in: PubMed
    56. Plotkowski ML, Kim S, Phillips ML, Partridge AW, Deber CM, Bowie JU. Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction. Biochemistry. 2007 Oct 30; 46(43):12164-73. PMID: 17915947.
      View in: PubMed
    57. Wehbi H, Gasmi-Seabrook G, Choi MY, Deber CM. Positional dependence of non-native polar mutations on folding of CFTR helical hairpins. Biochim Biophys Acta. 2008 Jan; 1778(1):79-87. PMID: 17949679.
      View in: PubMed
    58. Johnson RM, Hecht K, Deber CM. Aromatic and cation-pi interactions enhance helix-helix association in a membrane environment. Biochemistry. 2007 Aug 14; 46(32):9208-14. PMID: 17658897.
      View in: PubMed
    59. Glukhov E, Shulga YV, Epand RF, Dicu AO, Topham MK, Deber CM, Epand RM. Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon. Biochim Biophys Acta. 2007 Oct; 1768(10):2549-58. PMID: 17669357.
      View in: PubMed
    60. Kuo HH, Chan C, Burrows LL, Deber CM. Hydrophobic interactions in complexes of antimicrobial peptides with bacterial polysaccharides. Chem Biol Drug Des. 2007 Jun; 69(6):405-12. PMID: 17581234.
      View in: PubMed
    61. Wehbi H, Rath A, Glibowicka M, Deber CM. Role of the extracellular loop in the folding of a CFTR transmembrane helical hairpin. Biochemistry. 2007 Jun 19; 46(24):7099-106. PMID: 17516627.
      View in: PubMed
    62. Cunningham F, Deber CM. Optimizing synthesis and expression of transmembrane peptides and proteins. Methods. 2007 Apr; 41(4):370-80. PMID: 17367709.
      View in: PubMed
    63. Rath A, Deber CM. Membrane protein assembly patterns reflect selection for non-proliferative structures. FEBS Lett. 2007 Apr 03; 581(7):1335-41. PMID: 17350624.
      View in: PubMed
    64. Rath A, Johnson RM, Deber CM. Peptides as transmembrane segments: decrypting the determinants for helix-helix interactions in membrane proteins. Biopolymers. 2007; 88(2):217-32. PMID: 17206630.
      View in: PubMed
    65. Johnson RM, Rath A, Deber CM. The position of the Gly-xxx-Gly motif in transmembrane segments modulates dimer affinity. Biochem Cell Biol. 2006 Dec; 84(6):1006-12. PMID: 17215886.
      View in: PubMed
    66. Wellhauser L, Kuo HH, Stratford FL, Ramjeesingh M, Huan LJ, Luong W, Li C, Deber CM, Bear CE. Nucleotides bind to the C-terminus of ClC-5. Biochem J. 2006 Sep 01; 398(2):289-94. PMID: 16686597.
      View in: PubMed
    67. Johnson RM, Rath A, Melnyk RA, Deber CM. Lipid solvation effects contribute to the affinity of Gly-xxx-Gly motif-mediated helix-helix interactions. Biochemistry. 2006 Jul 18; 45(28):8507-15. PMID: 16834324.
      View in: PubMed
    68. Go MY, Kim S, Partridge AW, Melnyk RA, Rath A, Deber CM, Mogridge J. Self-association of the transmembrane domain of an anthrax toxin receptor. J Mol Biol. 2006 Jun 30; 360(1):145-56. PMID: 16756998.
      View in: PubMed
    69. Rath A, Melnyk RA, Deber CM. Evidence for assembly of small multidrug resistance proteins by a "two-faced" transmembrane helix. J Biol Chem. 2006 Jun 02; 281(22):15546-53. PMID: 16574656.
      View in: PubMed
    70. Burrows LL, Stark M, Chan C, Glukhov E, Sinnadurai S, Deber CM. Activity of novel non-amphipathic cationic antimicrobial peptides against Candida species. J Antimicrob Chemother. 2006 May; 57(5):899-907. PMID: 16524895.
      View in: PubMed
    71. Glukhov E, Stark M, Burrows LL, Deber CM. Basis for selectivity of cationic antimicrobial peptides for bacterial versus mammalian membranes. J Biol Chem. 2005 Oct 07; 280(40):33960-7. PMID: 16043484.
      View in: PubMed
    72. Chan C, Burrows LL, Deber CM. Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides. J Pept Res. 2005 Mar; 65(3):343-51. PMID: 15787964.
      View in: PubMed
    73. Rath A, Davidson AR, Deber CM. The structure of "unstructured" regions in peptides and proteins: role of the polyproline II helix in protein folding and recognition. Biopolymers. 2005; 80(2-3):179-85. PMID: 15700296.
      View in: PubMed
    74. Johnson RM, Heslop CL, Deber CM. Hydrophobic helical hairpins: design and packing interactions in membrane environments. Biochemistry. 2004 Nov 16; 43(45):14361-9. PMID: 15533040.
      View in: PubMed
    75. Choi MY, Partridge AW, Daniels C, Du K, Lukacs GL, Deber CM. Destabilization of the transmembrane domain induces misfolding in a phenotypic mutant of cystic fibrosis transmembrane conductance regulator. J Biol Chem. 2005 Feb 11; 280(6):4968-74. PMID: 15537638.
      View in: PubMed
    76. Chan C, Burrows LL, Deber CM. Helix induction in antimicrobial peptides by alginate in biofilms. J Biol Chem. 2004 Sep 10; 279(37):38749-54. PMID: 15247257.
      View in: PubMed
    77. Choi MY, Cardarelli L, Therien AG, Deber CM. Non-native interhelical hydrogen bonds in the cystic fibrosis transmembrane conductance regulator domain modulated by polar mutations. Biochemistry. 2004 Jun 29; 43(25):8077-83. PMID: 15209503.
      View in: PubMed
    78. Partridge AW, Therien AG, Deber CM. Missense mutations in transmembrane domains of proteins: phenotypic propensity of polar residues for human disease. Proteins. 2004 Mar 01; 54(4):648-56. PMID: 14997561.
      View in: PubMed
    79. Melnyk RA, Kim S, Curran AR, Engelman DM, Bowie JU, Deber CM. The affinity of GXXXG motifs in transmembrane helix-helix interactions is modulated by long-range communication. J Biol Chem. 2004 Apr 16; 279(16):16591-7. PMID: 14766751.
      View in: PubMed
    80. Tang YC, Deber CM. Aqueous solubility and membrane interactions of hydrophobic peptides with peptoid tags. Biopolymers. 2004; 76(2):110-8. PMID: 15054891.
      View in: PubMed
    81. George SR, Ng GY, Lee SP, Fan T, Varghese G, Wang C, Deber CM, Seeman P, O'Dowd BF. Blockade of G protein-coupled receptors and the dopamine transporter by a transmembrane domain peptide: novel strategy for functional inhibition of membrane proteins in vivo. J Pharmacol Exp Ther. 2003 Nov; 307(2):481-9. PMID: 12970389.
      View in: PubMed
    82. Zouzoulas A, Therien AG, Scanzano R, Deber CM, Blostein R. Modulation of Na,K-ATPase by the gamma subunit: studies with transfected cells and transmembrane mimetic peptides. J Biol Chem. 2003 Oct 17; 278(42):40437-41. PMID: 12907667.
      View in: PubMed
    83. Dawson JP, Melnyk RA, Deber CM, Engelman DM. Sequence context strongly modulates association of polar residues in transmembrane helices. J Mol Biol. 2003 Aug 01; 331(1):255-62. PMID: 12875850.
      View in: PubMed
    84. Partridge AW, Melnyk RA, Yang D, Bowie JU, Deber CM. A transmembrane segment mimic derived from Escherichia coli diacylglycerol kinase inhibits protein activity. J Biol Chem. 2003 Jun 13; 278(24):22056-60. PMID: 12686537.
      View in: PubMed
    85. Abdalla SA, Cymerman U, Johnson RM, Deber CM, Letarte M. Disease-associated mutations in conserved residues of ALK-1 kinase domain. Eur J Hum Genet. 2003 Apr; 11(4):279-87. PMID: 12700602.
      View in: PubMed
    86. Maeda M, Melnyk RA, Partridge AW, Liu LP, Deber CM. Transmembrane segment peptides with double D-amino acid replacements: helicity, hydrophobicity, and antimicrobial activity. Biopolymers. 2003; 71(1):77-84. PMID: 12712502.
      View in: PubMed
    87. Melnyk RA, Partridge AW, Yip J, Wu Y, Goto NK, Deber CM. Polar residue tagging of transmembrane peptides. Biopolymers. 2003; 71(6):675-85. PMID: 14991677.
      View in: PubMed
    88. Tang YC, Deber CM. Hydrophobicity and helicity of membrane-interactive peptides containing peptoid residues. Biopolymers. 2002 Nov 15; 65(4):254-62. PMID: 12382286.
      View in: PubMed
    89. Stark M, Liu LP, Deber CM. Cationic hydrophobic peptides with antimicrobial activity. Antimicrob Agents Chemother. 2002 Nov; 46(11):3585-90. PMID: 12384369.
      View in: PubMed
    90. Therien AG, Deber CM. Oligomerization of a peptide derived from the transmembrane region of the sodium pump gamma subunit: effect of the pathological mutation G41R. J Mol Biol. 2002 Sep 20; 322(3):583-50. PMID: 12225751.
      View in: PubMed
    91. Therien AG, Glibowicka M, Deber CM. Expression and purification of two hydrophobic double-spanning membrane proteins derived from the cystic fibrosis transmembrane conductance regulator. Protein Expr Purif. 2002 Jun; 25(1):81-6. PMID: 12071702.
      View in: PubMed
    92. Deber CM, Therien AG. Putting the beta-breaks on membrane protein misfolding. Nat Struct Biol. 2002 May; 9(5):318-9. PMID: 11976722.
      View in: PubMed
    93. Partridge AW, Melnyk RA, Deber CM. Polar residues in membrane domains of proteins: molecular basis for helix-helix association in a mutant CFTR transmembrane segment. Biochemistry. 2002 Mar 19; 41(11):3647-53. PMID: 11888281.
      View in: PubMed
    94. Melnyk RA, Partridge AW, Deber CM. Transmembrane domain mediated self-assembly of major coat protein subunits from Ff bacteriophage. J Mol Biol. 2002 Jan 04; 315(1):63-72. PMID: 11771966.
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    95. Partridge AW, Therien AG, Deber CM. Polar mutations in membrane proteins as a biophysical basis for disease. Biopolymers. 2002; 66(5):350-8. PMID: 12539263.
      View in: PubMed
    96. Therien AG, Deber CM. Interhelical packing in detergent micelles. Folding of a cystic fibrosis transmembrane conductance regulator construct. J Biol Chem. 2002 Feb 22; 277(8):6067-72. PMID: 11748233.
      View in: PubMed
    97. Melnyk RA, Partridge AW, Deber CM. Retention of native-like oligomerization states in transmembrane segment peptides: application to the Escherichia coli aspartate receptor. Biochemistry. 2001 Sep 18; 40(37):11106-13. PMID: 11551208.
      View in: PubMed
    98. Therien AG, Grant FE, Deber CM. Interhelical hydrogen bonds in the CFTR membrane domain. Nat Struct Biol. 2001 Jul; 8(7):597-601. PMID: 11427889.
      View in: PubMed
    99. Deber CM, Wang C, Liu LP, Prior AS, Agrawal S, Muskat BL, Cuticchia AJ. TM Finder: a prediction program for transmembrane protein segments using a combination of hydrophobicity and nonpolar phase helicity scales. Protein Sci. 2001 Jan; 10(1):212-9. PMID: 11266608.
      View in: PubMed
    100. Yuen CT, Davidson AR, Deber CM. Role of aromatic residues at the lipid-water interface in micelle-bound bacteriophage M13 major coat protein. Biochemistry. 2000 Dec 26; 39(51):16155-62. PMID: 11123944.
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    101. Wang C, Deber CM. Peptide mimics of the M13 coat protein transmembrane segment. Retention of helix-helix interaction motifs. J Biol Chem. 2000 May 26; 275(21):16155-9. PMID: 10747951.
      View in: PubMed
    102. Pomroy NC, Deber CM. Conjugation of polyethylene glycol via a disulfide bond confers water solubility upon a peptide model of a protein transmembrane segment. Anal Biochem. 1999 Nov 15; 275(2):224-30. PMID: 10552908.
      View in: PubMed
    103. Deber CM, Liu LP, Wang C. Perspective: peptides as mimics of transmembrane segments in proteins. J Pept Res. 1999 Sep; 54(3):200-5. PMID: 10517157.
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    104. Liu LP, Deber CM. Combining hydrophobicity and helicity: a novel approach to membrane protein structure prediction. Bioorg Med Chem. 1999 Jan; 7(1):1-7. PMID: 10199651.
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    105. Liu LP, Deber CM. Uncoupling hydrophobicity and helicity in transmembrane segments. Alpha-helical propensities of the amino acids in non-polar environments. J Biol Chem. 1998 Sep 11; 273(37):23645-8. PMID: 9726967.
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    106. Peng S, Liu LP, Emili AQ, Deber CM. Cystic fibrosis transmembrane conductance regulator: expression and helicity of a double membrane-spanning segment. FEBS Lett. 1998 Jul 10; 431(1):29-33. PMID: 9684859.
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    107. Pomroy NC, Deber CM. Solubilization of hydrophobic peptides by reversible cysteine PEGylation. Biochem Biophys Res Commun. 1998 Apr 17; 245(2):618-21. PMID: 9571204.
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    108. Liu LP, Deber CM. Guidelines for membrane protein engineering derived from de novo designed model peptides. Biopolymers. 1998; 47(1):41-62. PMID: 9692326.
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    109. Malaney S, Trumpower BL, Deber CM, Robinson BH. The N terminus of the Qcr7 protein of the cytochrome bc1 complex is not essential for import into mitochondria in Saccharomyces cerevisiae but is essential for assembly of the complex. J Biol Chem. 1997 Jul 11; 272(28):17495-501. PMID: 9211895.
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    110. Liu LP, Deber CM. Anionic phospholipids modulate peptide insertion into membranes. Biochemistry. 1997 May 06; 36(18):5476-82. PMID: 9154930.
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    111. Deber CM, Goto NK. Folding proteins into membranes. Nat Struct Biol. 1996 Oct; 3(10):815-8. PMID: 8836094.
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    112. Liu LP, Li SC, Goto NK, Deber CM. Threshold hydrophobicity dictates helical conformations of peptides in membrane environments. Biopolymers. 1996 Sep; 39(3):465-70. PMID: 8756523.
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    113. Williams KA, Deber CM. Biophysical characterization of wild-type and mutant bacteriophage IKe major coat protein in the virion and in detergent micelles. Biochemistry. 1996 Aug 13; 35(32):10472-83. PMID: 8756704.
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    114. Li SC, Goto NK, Williams KA, Deber CM. Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6676-81. PMID: 8692877.
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    115. Williams KA, Farrow NA, Deber CM, Kay LE. Structure and dynamics of bacteriophage IKe major coat protein in MPG micelles by solution NMR. Biochemistry. 1996 Apr 23; 35(16):5145-57. PMID: 8611498.
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    116. Khan AR, Williams KA, Boggs JM, Deber CM. Accessibility and dynamics of Cys residues in Bacteriophage IKe and M13 major coat protein mutants. Biochemistry. 1995 Sep 26; 34(38):12388-97. PMID: 7547983.
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    117. Williams KA, Glibowicka M, Li Z, Li H, Khan AR, Chen YM, Wang J, Marvin DA, Deber CM. Packing of coat protein amphipathic and transmembrane helices in filamentous bacteriophage M13: role of small residues in protein oligomerization. J Mol Biol. 1995 Sep 08; 252(1):6-14. PMID: 7666434.
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    118. Li SC, Kim PK, Deber CM. Manipulation of peptide conformations by fine-tuning of the environment and/or the primary sequence. Biopolymers. 1995 Jun; 35(6):667-75. PMID: 7766831.
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    119. Khan AR, Deber CM. An engineered disulfide bridge in the transmembrane region of phage M13 coat protein stabilizes the alpha-helical dimer. Biochem Biophys Res Commun. 1995 Jan 05; 206(1):230-7. PMID: 7818525.
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    120. Deber CM, Li SC. Peptides in membranes: helicity and hydrophobicity. Biopolymers. 1995; 37(5):295-318. PMID: 7632880.
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    121. Li SC, Deber CM, Shoelson SE. An irregularity in the transmembrane domain helix correlates with the rate of insulin receptor internalization. Biochemistry. 1994 Nov 29; 33(47):14333-8. PMID: 7947843.
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    122. Li SC, Deber CM. A measure of helical propensity for amino acids in membrane environments. Nat Struct Biol. 1994 Aug; 1(8):558. PMID: 7664085.
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    123. Li SC, Deber CM. A measure of helical propensity for amino acids in membrane environments. Nat Struct Biol. 1994 Jun; 1(6):368-73. PMID: 7664049.
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    124. Pawagi AB, Wang J, Silverman M, Reithmeier RA, Deber CM. Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. J Mol Biol. 1994 Jan 14; 235(2):554-64. PMID: 7904655.
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    125. Deber CM, Khan AR, Li Z, Joensson C, Glibowicka M, Wang J. Val-->Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11648-52. PMID: 8265602.
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    126. Li SC, Deber CM. Peptide environment specifies conformation. Helicity of hydrophobic segments compared in aqueous, organic, and membrane environments. J Biol Chem. 1993 Nov 05; 268(31):22975-8. PMID: 8226811.
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    127. Williams KA, Deber CM. Mutagenesis of bacteriophage IKe major coat protein transmembrane domain: role of an interfacial proline residue. Biochem Biophys Res Commun. 1993 Oct 15; 196(1):1-6. PMID: 8216279.
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    128. Li Z, Glibowicka M, Joensson C, Deber CM. Conformational states of mutant M13 coat proteins are regulated by transmembrane residues. J Biol Chem. 1993 Mar 05; 268(7):4584-7. PMID: 8444834.
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    129. Landolt-Marticorena C, Williams KA, Deber CM, Reithmeier RA. Non-random distribution of amino acids in the transmembrane segments of human type I single span membrane proteins. J Mol Biol. 1993 Feb 05; 229(3):602-8. PMID: 8433362.
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    130. Williams KA, Deber CM. The structure and function of central nervous system myelin. Crit Rev Clin Lab Sci. 1993; 30(1):29-64. PMID: 7683887.
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    131. Li SC, Deber CM. Glycine and beta-branched residues support and modulate peptide helicity in membrane environments. FEBS Lett. 1992 Oct 26; 311(3):217-20. PMID: 1397317.
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    132. Li SC, Deber CM. Influence of glycine residues on peptide conformation in membrane environments. Int J Pept Protein Res. 1992 Sep-Oct; 40(3-4):243-8. PMID: 1478781.
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    133. Polinsky A, Goodman M, Williams KA, Deber CM. Minimum energy conformations of proline-containing helices. Biopolymers. 1992 Apr; 32(4):399-406. PMID: 1623135.
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    134. Deber CM, Li Z, Joensson C, Glibowicka M, Xu GY. Transmembrane region of wild-type and mutant M13 coat proteins. Conformational role of beta-branched residues. J Biol Chem. 1992 Mar 15; 267(8):5296-300. PMID: 1544912.
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    135. Li Z, Deber CM. Viable transmembrane region mutants of bacteriophage M13 coat protein prepared by site-directed mutagenesis. Biochem Biophys Res Commun. 1991 Oct 31; 180(2):687-93. PMID: 1953741.
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    136. Williams KA, Deber CM. Proline residues in transmembrane helices: structural or dynamic role? Biochemistry. 1991 Sep 17; 30(37):8919-23. PMID: 1892808.
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    137. Xu GY, Deber CM. Conformations of neurotensin in solution and in membrane environments studied by 2-D NMR spectroscopy. Int J Pept Protein Res. 1991 Jun; 37(6):528-35. PMID: 1917311.
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    138. Deber CM, Reynolds SJ. Central nervous system myelin: structure, function, and pathology. Clin Biochem. 1991 Apr; 24(2):113-34. PMID: 1710177.
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    139. Deber CM, Sorrell BJ, Xu GY. Conformation of proline residues in bacteriorhodopsin. Biochem Biophys Res Commun. 1990 Oct 30; 172(2):862-9. PMID: 2241974.
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    140. Pawagi AB, Deber CM. Ligand-dependent quenching of tryptophan fluorescence in human erythrocyte hexose transport protein. Biochemistry. 1990 Jan 30; 29(4):950-5. PMID: 2340286.
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    141. Deber CM, Glibowicka M, Woolley GA. Conformations of proline residues in membrane environments. Biopolymers. 1990 Jan; 29(1):149-57. PMID: 2328283.
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    142. Fraser PE, Rand RP, Deber CM. Bilayer-stabilizing properties of myelin basic protein in dioleoylphosphatidylethanolamine systems. Biochim Biophys Acta. 1989 Jul 24; 983(1):23-9. PMID: 2474328.
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    143. Deber CM, Lutek MK, Heimer EP, Felix AM. Conformational origin of a difficult coupling in a human growth hormone releasing factor analog. Pept Res. 1989 Mar-Apr; 2(2):184-8. PMID: 2520756.
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    144. Woolley GA, Deber CM. A lipid vesicle system for probing voltage-dependent peptide-lipid interactions: application to alamethicin channel formation. Biopolymers. 1989 Jan; 28(1):267-72. PMID: 2470433.
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    145. Brandl CJ, Deber RB, Hsu LC, Woolley GA, Young XK, Deber CM. Evidence for similar function of transmembrane segments in receptor and membrane-anchored proteins. Biopolymers. 1988 Jul; 27(7):1171-82. PMID: 2850033.
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    146. Lutek MK, Hofmann T, Deber CM. Transpeptidation reactions of porcine pepsin. Formation of tetrapeptides from dipeptide substrates. J Biol Chem. 1988 Jun 15; 263(17):8011-6. PMID: 3131336.
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    147. Pawagi AB, Deber CM. D-glucose binding increases secondary structure of human erythrocyte monosaccharide transport protein. Biochem Biophys Res Commun. 1987 Jun 30; 145(3):1087-91. PMID: 3606595.
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    148. Woolley GA, Deber CM. Peptides in membranes: lipid-induced secondary structure of substance P. Biopolymers. 1987; 26 Suppl:S109-21. PMID: 2437975.
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    149. Fraser PE, Moscarello MA, Rand RP, Deber CM. Spontaneous vesicularization of myelin lipids is counteracted by myelin basic protein. Biochim Biophys Acta. 1986 Dec 16; 863(2):282-8. PMID: 2431713.
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    150. Deber CM, Brandl CJ, Deber RB, Hsu LC, Young XK. Amino acid composition of the membrane and aqueous domains of integral membrane proteins. Arch Biochem Biophys. 1986 Nov 15; 251(1):68-76. PMID: 3789746.
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    151. Moscarello MA, Mitranic MM, Deber CM. The modulation of bovine milk D-galactosyltransferase by various phosphatidylethanolamines. Carbohydr Res. 1986 Jun 01; 149(1):47-58. PMID: 3089603.
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    152. Deber CM, Hughes DW, Fraser PE, Pawagi AB, Moscarello MA. Binding of human normal and multiple sclerosis-derived myelin basic protein to phospholipid vesicles: effects on membrane head group and bilayer regions. Arch Biochem Biophys. 1986 Mar; 245(2):455-63. PMID: 2420275.
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    153. Brandl CJ, Deber CM. Hypothesis about the function of membrane-buried proline residues in transport proteins. Proc Natl Acad Sci U S A. 1986 Feb; 83(4):917-21. PMID: 3456574.
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    154. Deber CM, Hsu LC. Calcium transport by ionophorous peptides in dog and human lymphocytes detected by quin-2 fluorescence. Biochem Biophys Res Commun. 1986 Jan 29; 134(2):731-5. PMID: 3947349.
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    155. Fraser PE, Deber CM. Structure and function of the proline-rich region of myelin basic protein. Biochemistry. 1985 Aug 13; 24(17):4593-8. PMID: 2415158.
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    156. Deber CM, Tom-Kun J, Mack E, Grinstein S. Bromo-A23187: a nonfluorescent calcium ionophore for use with fluorescent probes. Anal Biochem. 1985 May 01; 146(2):349-52. PMID: 3927770.
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    157. Behnam BA, Deber CM. Evidence for a folded conformation of methionine- and leucine-enkephalin in a membrane environment. J Biol Chem. 1984 Dec 10; 259(23):14935-40. PMID: 6501322.
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    158. Cheifetz S, Moscarello MA, Deber CM. NMR investigation of the charge isomers of bovine myelin basic protein. Arch Biochem Biophys. 1984 Aug 15; 233(1):151-60. PMID: 6205629.
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    159. Fraser PE, Deber CM. Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein. J Biol Chem. 1984 Jul 25; 259(14):8689-92. PMID: 6204974.
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    160. Deber CM, Behnam BA. Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles. Proc Natl Acad Sci U S A. 1984 Jan; 81(1):61-5. PMID: 6320173.
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    161. Deber CM, Cheifetz S, Moscarello MA. Microheterogeneity of bovine myelin basic protein studied by nuclear magnetic resonance spectroscopy. Biopolymers. 1983 Jan; 22(1):377-80. PMID: 6201203.
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    162. Drobnies AE, Deber CM. Cation transport properties of a synthetic Ca2+-selective peptide ionophore in phospholipid and sarcoplasmic reticulum vesicles. Biochim Biophys Acta. 1982 Sep 24; 691(1):30-6. PMID: 6128028.
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    163. Hughes DW, Stollery JG, Moscarello MA, Deber CM. Binding of myelin basic protein to phospholipid micelles. J Biol Chem. 1982 May 10; 257(9):4698-700. PMID: 6175644.
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    164. Hughes DW, Deber CM. Conformations of cyclic peptide/calcium complexes in solution. Biopolymers. 1982 Jan; 21(1):169-79. PMID: 7055630.
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    165. Debono M, Molloy RM, Dorman DE, Paschal JW, Babcock DF, Deber CM, Pfeiffer DR. Synthesis and characterization of halogenated derivatives of the ionophore A23187: enhanced calcium ion transport specificity by the 4-bromo derivative. Biochemistry. 1981 Nov 24; 20(24):6865-72. PMID: 6797465.
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    166. Boggs JM, Stamp D, Hughes DW, Deber CM. Influence of ether linkage on the lamellar to hexagonal phase transition of ethanolamine phospholipids. Biochemistry. 1981 Sep 29; 20(20):5728-35. PMID: 6271192.
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    167. Gierasch LM, Deber CM, Madison V, Niu CH, Blout ER. Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins. Biochemistry. 1981 Aug 04; 20(16):4730-8. PMID: 7295645.
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    168. Deber CM, Young ME, Tom-Kun J. Synthetic cation transport peptides: calcium transport across phospholipid membranes. Biochemistry. 1980 Dec 23; 19(26):6194-8. PMID: 7470459.
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    169. Chan YM, Soldin SJ, Swanson JM, Deber CM, Thiessen JJ, Macleod S. Gas chromatographic/mass spectrometric analysis of methylphenidate (ritalin) in serum. Clin Biochem. 1980 Dec; 13(6):266-72. PMID: 7214694.
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    170. Deber CM. Peptide models for protein-mediated cation transport. Can J Biochem. 1980 Oct; 58(10):865-70. PMID: 6780166.
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    171. Stollery JG, Boggs JM, Moscarello MA, Deber CM. Direct observation by carbon-13 nuclear magnetic resonance of membrane-bound human myelin basic protein. Biochemistry. 1980 May 27; 19(11):2391-6. PMID: 6155938.
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    172. Deber CM, Adawadkar PD. Cation-binding cyclic peptides with lipophilic tails. Biopolymers. 1979 Oct; 18(10):2375-96. PMID: 526545.
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    173. Pfeiffer DR, Deber CM. Isosteric metal complexes of ionophore A23187: a basis for cation selectivity. FEBS Lett. 1979 Sep 15; 105(2):360-4. PMID: 385347.
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    174. Deber CM, Young ME. Association of carbon-13 enriched human encephalitogenic nonapeptide with a membrane surface. J Biol Chem. 1979 Jul 25; 254(14):6341-5. PMID: 87395.
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    175. Deber CM, Adawadkar PD, Tom-Kun J. Synthesis of an ion-binding peptide (DECYL-2) more selective for calcium than ionophore A23187. Biochem Biophys Res Commun. 1978 Apr 28; 81(4):1357-62. PMID: 352356.
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    176. Deber CM, Moscarello MA, Wood DD. Conformational studies on 13C-enriched human and bovine myelin basic protein, in solution and incorporated into liposomes. Biochemistry. 1978 Mar 07; 17(5):898-903. PMID: 75742.
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    177. Madison V, Deber CM, Blout ER. Cyclic peptides. 17. Metal and amino acid complexes of cyclo(pro-gly)4 and analogues studied by nuclear magnetic resonance and circular dichroism. J Am Chem Soc. 1977 Jul 06; 99(14):4788-98. PMID: 874230.
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    178. Bartman B, Deber CM, Blout ER. 13C NMR relaxation studies of complexes between cyclo(L-Pro-Gly)3 and amino acids. Conformational aspects of stepwise binding. J Am Chem Soc. 1977 Feb 16; 99(4):1028-33. PMID: 833392.
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    179. Deber CM, Pfieffer DR. Ionophore A23187. Solution conformations of the calcium complex and free acid deduced from proton and carbon-13 nuclear magnetic resonance studies. Biochemistry. 1976 Jan 13; 15(1):132-41. PMID: 764856.
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    180. Young RE, Deber CM. Letter: Long-range steric effects on rotational barriers in peptide chains. Biopolymers. 1975 Jul; 14(7):1547-9. PMID: 1164560.
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    181. Deber CM, Blout ER. Letter: Amino acid-cyclic peptide complexes. J Am Chem Soc. 1974 Nov 27; 96(24):7566-8. PMID: 4427067.
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    182. Madison V, Atreyi M, Deber CM, Blout ER. Cyclic peptides. IX. Conformations of a synthetic ion-binding cyclic peptide, cyclo-(pro-gly)3, from circular dichroism and 1H and 13C nuclear magnetic resonance. J Am Chem Soc. 1974 Oct 16; 96(21):6725-34. PMID: 4412689.
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    183. Deber CM. Evidence for beta-turn analogs in proline peptides in the solid state. An infrared study. Macromolecules. 1974 Jan-Feb; 7(1):52-8. PMID: 4837982.
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    184. Pease LG, Deber CM, Blout ER. Cyclic peptides. V. 1 H and 13 C nuclear magnetic resonance determination of the preferred beta conformation for proline-containing cyclic hexapeptides. J Am Chem Soc. 1973 Jan 10; 95(1):258-60. PMID: 4682895.
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    185. Deber CM, Torchia DA, Wong SC, Blout ER. Conformational interconversions of the cyclic hexapeptide cyclo(Pro-Gly) 3 . Proc Natl Acad Sci U S A. 1972 Jul; 69(7):1825-9. PMID: 4505660.
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    186. Torchia DA, Deber CM. Evidence for stereospecific collision complexes of cyclo(tri-L-prolyl) with benzene. Biopolymers. 1972 Mar; 11(3):653-9. PMID: 5016122.
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    187. Torchia DA, Di Corato A, Wong SC, Deber CM, Blout ER. Cyclic peptides. II. Solution conformations of cyclo(ProlyLserylglycylprolylserylglycyl) from nuclear magnetic resonance. J Am Chem Soc. 1972 Jan 26; 94(2):609-15. PMID: 5060991.
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    188. Torchia DA, Wong SC, Deber CM, Blout ER. Cyclic peptides. 3. Solution conformations of cyclo(serylprolylglycylserylprolylglycyl) from nuclear magnetic resonance. J Am Chem Soc. 1972 Jan 26; 94(2):616-20. PMID: 5060992.
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    189. Deber CM, Joshua H. Side chain interactions in aromatic dipeptides. Biopolymers. 1972; 11(12):2493-503. PMID: 4649730.
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    190. Deber CM, Torchia DA, Blout ER. Cyclic peptides. I. Cyclo(tri-l-prolyl) and derivatives. Synthesis and molecular conformation from nuclear magnetic resonance. J Am Chem Soc. 1971 Sep; 93(19):4893-7. PMID: 5118215.
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    191. Deber CM, Bovey FA, Carver JP, Blout ER. Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers. J Am Chem Soc. 1970 Oct 21; 92(21):6191-8. PMID: 5505620.
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    192. GOODMAN M, FELIX AM, DEBER CM, BRAUSE AR. SIDE CHAIN EFFECTS ON POLYPEPTIDE HELICES. THE NITROAROMATIC EFFECT. Biopolym Symp. 1964; 13:409-20. PMID: 14210465.
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