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Clifford Lingwood

TitleSenior Scientist, Microbiology
InstitutionThe Hospital for Sick Children
DepartmentMolecular Medicine
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A. Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling. Sci Rep. 2018 01 16; 8(1):850. PMID: 29339801.
      View in: PubMed
    2. Grosso F, Stoilov P, Lingwood C, Brown M, Cochrane A. Suppression of Adenovirus Replication by Cardiotonic Steroids. J Virol. 2017 Feb 01; 91(3). PMID: 27881644.
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    3. Adnan H, Zhang Z, Park HJ, Tailor C, Che C, Kamani M, Spitalny G, Binnington B, Lingwood C. Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases. PLoS One. 2016; 11(12):e0166948. PMID: 27935997.
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    4. Kamani MA, Provençal P, Boutin M, Pacienza N, Fan X, Novak A, Huang TC, Binnington B, Au BC, Auray-Blais C, Lingwood CA, Medin JA. Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion. Future Sci OA. 2016 Dec; 2(4):FSO147. PMID: 28116130.
      View in: PubMed
    5. Budani M, Mylvaganam M, Binnington B, Lingwood C. Synthesis of a novel photoactivatable glucosylceramide cross-linker. J Lipid Res. 2016 09; 57(9):1728-36. PMID: 27412675.
      View in: PubMed
    6. Binnington B, Nguyen L, Kamani M, Hossain D, Marks DL, Budani M, Lingwood CA. Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling. Glycobiology. 2016 Feb; 26(2):166-80. PMID: 26405105.
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    7. Novak A, Binnington B, Ngan B, Chadwick K, Fleshner N, Lingwood CA. Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodetection in human cancer biopsies. Glycobiology. 2013 Nov; 23(11):1230-9. PMID: 23906628.
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    8. Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR. CD4(+) T-cells are unable to express the HIV natural resistance factor globotriosylceramide. AIDS. 2013 Mar 27; 27(6):1029-32. PMID: 23380967.
      View in: PubMed
    9. Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C. Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro. Toxins (Basel). 2012 Dec 14; 4(12):1517-34. PMID: 23242319.
      View in: PubMed
    10. Saito M, Mylvaganum M, Tam P, Novak A, Binnington B, Lingwood C. Structure-dependent pseudoreceptor intracellular traffic of adamantyl globotriaosyl ceramide mimics. J Biol Chem. 2012 May 11; 287(20):16073-87. PMID: 22418442.
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    11. Gerl MJ, Sampaio JL, Urban S, Kalvodova L, Verbavatz JM, Binnington B, Lindemann D, Lingwood CA, Shevchenko A, Schroeder C, Simons K. Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane. J Cell Biol. 2012 Jan 23; 196(2):213-21. PMID: 22249292.
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    12. Lingwood CA. Glycosphingolipid functions. Cold Spring Harb Perspect Biol. 2011 Jul 01; 3(7). PMID: 21555406.
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    13. Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR. Comparison of detection methods for cell surface globotriaosylceramide. J Immunol Methods. 2011 Aug 31; 371(1-2):48-60. PMID: 21726561.
      View in: PubMed
    14. Kamani M, Mylvaganam M, Tian R, Rigat B, Binnington B, Lingwood C. Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism. J Biol Chem. 2011 Jun 17; 286(24):21413-26. PMID: 21518770.
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    15. Lingwood D, Binnington B, Róg T, Vattulainen I, Grzybek M, Coskun U, Lingwood CA, Simons K. Cholesterol modulates glycolipid conformation and receptor activity. Nat Chem Biol. 2011 May; 7(5):260-2. PMID: 21460830.
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    16. Lingwood CA, Branch DR. The role of glycosphingolipids in HIV/AIDS. Discov Med. 2011 Apr; 11(59):303-13. PMID: 21524384.
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    17. Emam A, Carter WG, Lingwood C. Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells. Open Microbiol J. 2010 Dec 13; 4:106-15. PMID: 21270937.
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    18. Mahfoud R, Manis A, Binnington B, Ackerley C, Lingwood CA. A major fraction of glycosphingolipids in model and cellular cholesterol-containing membranes is undetectable by their binding proteins. J Biol Chem. 2010 Nov 12; 285(46):36049-59. PMID: 20716521.
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    19. Harrison AL, Olsson ML, Jones RB, Ramkumar S, Sakac D, Binnington B, Henry S, Lingwood CA, Branch DR. A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms. Glycoconj J. 2010 Jul; 27(5):515-24. PMID: 20582467.
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    20. Lingwood CA, Manis A, Mahfoud R, Khan F, Binnington B, Mylvaganam M. New aspects of the regulation of glycosphingolipid receptor function. Chem Phys Lipids. 2010 Jan; 163(1):27-35. PMID: 19781539.
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    21. Lingwood CA, Binnington B, Manis A, Branch DR. Globotriaosyl ceramide receptor function - where membrane structure and pathology intersect. FEBS Lett. 2010 May 03; 584(9):1879-86. PMID: 19948172.
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    22. Park HJ, Mylvaganum M, McPherson A, Fewell SW, Brodsky JL, Lingwood CA. A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation. Chem Biol. 2009 Apr 24; 16(4):461-70. PMID: 19389632.
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    23. Khan F, Proulx F, Lingwood CA. Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology. Kidney Int. 2009 Jun; 75(11):1209-1216. PMID: 19212418.
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    24. Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL. Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res. 2009 Apr; 141(1):71-80. PMID: 19200446.
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    25. Lund N, Olsson ML, Ramkumar S, Sakac D, Yahalom V, Levene C, Hellberg A, Ma XZ, Binnington B, Jung D, Lingwood CA, Branch DR. The human P(k) histo-blood group antigen provides protection against HIV-1 infection. Blood. 2009 May 14; 113(20):4980-91. PMID: 19139081.
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    26. Yonekawa S, Lingwood CA, Mylvaganam M. Oxidation of the primary hydroxyl group of galactose of galactaosyl ceramide analogue by chemical method-precursors for the synthesis of labeled conjugates. Carbohydr Res. 2009 Mar 10; 344(4):501-6. PMID: 19144327.
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    27. Ramkumar S, Sakac D, Binnington B, Branch DR, Lingwood CA. Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels. Glycobiology. 2009 Jan; 19(1):76-82. PMID: 18842961.
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    28. Tam P, Mahfoud R, Nutikka A, Khine AA, Binnington B, Paroutis P, Lingwood C. Differential intracellular transport and binding of verotoxin 1 and verotoxin 2 to globotriaosylceramide-containing lipid assemblies. J Cell Physiol. 2008 Sep; 216(3):750-63. PMID: 18446787.
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    29. Mahfoud R, Manis A, Lingwood CA. Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes. J Lipid Res. 2009 Sep; 50(9):1744-55. PMID: 18716315.
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    30. Fujii J, Wood K, Matsuda F, Carneiro-Filho BA, Schlegel KH, Yutsudo T, Binnington-Boyd B, Lingwood CA, Obata F, Kim KS, Yoshida S, Obrig T. Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein. Infect Immun. 2008 Aug; 76(8):3679-89. PMID: 18541659.
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    31. De Rosa MF, Ackerley C, Wang B, Ito S, Clarke DM, Lingwood C. Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog. J Biol Chem. 2008 Feb 22; 283(8):4501-11. PMID: 18003606.
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    32. De Rosa M, Park HJ, Mylvaganum M, Binnington B, Lund N, Branch DR, Lingwood CA. The medium is the message: glycosphingolipids and their soluble analogues. Biochim Biophys Acta. 2008 Mar; 1780(3):347-52. PMID: 18022400.
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    33. Tam PJ, Lingwood CA. Membrane cytosolic translocation of verotoxin A1 subunit in target cells. Microbiology. 2007 Aug; 153(Pt 8):2700-10. PMID: 17660434.
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    34. Emam A, Yu AR, Park HJ, Mahfoud R, Kus J, Burrows LL, Lingwood CA. Laboratory and clinical Pseudomonas aeruginosa strains do not bind glycosphingolipids in vitro or during type IV pili-mediated initial host cell attachment. Microbiology. 2006 Sep; 152(Pt 9):2789-99. PMID: 16946273.
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    35. Mattocks M, Bagovich M, De Rosa M, Bond S, Binnington B, Rasaiah VI, Medin J, Lingwood C. Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1. Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model. FEBS J. 2006 May; 273(9):2064-75. PMID: 16724420.
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    36. Lund N, Branch DR, Mylvaganam M, Chark D, Ma XZ, Sakac D, Binnington B, Fantini J, Puri A, Blumenthal R, Lingwood CA. A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection. AIDS. 2006 Feb 14; 20(3):333-43. PMID: 16439866.
      View in: PubMed
    37. Lingwood C, Sadacharan S, Abul-Milh M, Mylvaganum M, Peter M. Soluble adamantyl glycosphingolipid analogs as probes of glycosphingolipid function. Methods Mol Biol. 2006; 347:305-20. PMID: 17072019.
      View in: PubMed
    38. Lund N, Branch DR, Sakac D, Lingwood CA, Siatskas C, Robinson CJ, Brady RO, Medin JA. Lack of susceptibility of cells from patients with Fabry disease to productive infection with R5 human immunodeficiency virus. AIDS. 2005 Sep 23; 19(14):1543-6. PMID: 16135910.
      View in: PubMed
    39. Lingwood C, Mylvaganam M, Minhas F, Binnington B, Branch DR, Pomès R. The sulfogalactose moiety of sulfoglycosphingolipids serves as a mimic of tyrosine phosphate in many recognition processes. Prediction and demonstration of Src homology 2 domain/sulfogalactose binding. J Biol Chem. 2005 Apr 01; 280(13):12542-7. PMID: 15634687.
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    40. Khine AA, Tam P, Nutikka A, Lingwood CA. Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity. Glycobiology. 2004 Aug; 14(8):701-12. PMID: 15102715.
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    41. Nutikka A, Lingwood C. Generation of receptor-active, globotriaosyl ceramide/cholesterol lipid 'rafts' in vitro : A new assay to define factors affecting glycosphingolipid receptor activity. Glycoconj J. 2004; 20(1):33-8. PMID: 14973368.
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    42. Chark D, Nutikka A, Trusevych N, Kuzmina J, Lingwood C. Differential carbohydrate epitope recognition of globotriaosyl ceramide by verotoxins and a monoclonal antibody. Eur J Biochem. 2004 Jan; 271(2):405-17. PMID: 14717708.
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    43. De Rosa MF, Sillence D, Ackerley C, Lingwood C. Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis. J Biol Chem. 2004 Feb 27; 279(9):7867-76. PMID: 14662772.
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    44. Maloney M, Lingwood C. Synergistic effect of verotoxin and interferon-alpha on erythropoiesis. Cell Mol Biol (Noisy-le-grand). 2003 Dec; 49(8):1363-9. PMID: 14984011.
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    45. Whetstone H, Lingwood C. 3'Sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro. Biochemistry. 2003 Feb 18; 42(6):1611-7. PMID: 12578374.
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    46. Hoey DE, Sharp L, Currie C, Lingwood CA, Gally DL, Smith DG. Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity. Cell Microbiol. 2003 Feb; 5(2):85-97. PMID: 12580945.
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    47. Obrig TG, Seaner RM, Bentz M, Lingwood CA, Boyd B, Smith A, Narrow W. Induction by sphingomyelinase of shiga toxin receptor and shiga toxin 2 sensitivity in human microvascular endothelial cells. Infect Immun. 2003 Feb; 71(2):845-9. PMID: 12540565.
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    48. Heath-Engel HM, Lingwood CA. Verotoxin sensitivity of ECV304 cells in vitro and in vivo in a xenograft tumour model: VT1 as a tumour neovascular marker. Angiogenesis. 2003; 6(2):129-41. PMID: 14739619.
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    49. Lingwood CA, Mylvaganam M. Lipid modulation of glycosphingolipid (GSL) receptors: soluble GSL mimics provide new probes of GSL receptor function. Methods Enzymol. 2003; 363:264-83. PMID: 14579581.
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    50. Lingwood CA. Shiga toxin receptor glycolipid binding. Pathology and utility. Methods Mol Med. 2003; 73:165-86. PMID: 12375428.
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    51. Nutikka A, Binnington-Boyd B, Lingwood CA. Methods for the purification of Shiga toxin 1. Methods Mol Med. 2003; 73:187-95. PMID: 12375429.
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    52. Nutikka A, Binnington-Boyd B, Lingwood CA. Methods for the identification of host receptors for Shiga toxin. Methods Mol Med. 2003; 73:197-208. PMID: 12375430.
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    53. Mylvaganam M, Hansen HC, Binnington B, Magnusson G, Nyholm PG, Lingwood CA. Interaction of the verotoxin 1B subunit with soluble aminodeoxy analogues of globotriaosyl ceramides. Biochem J. 2002 Dec 15; 368(Pt 3):769-76. PMID: 12175338.
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    54. Mahfoud R, Mylvaganam M, Lingwood CA, Fantini J. A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb(3)), eliminates the cholesterol requirement for high affinity gp120/Gb(3) interaction. J Lipid Res. 2002 Oct; 43(10):1670-9. PMID: 12364551.
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    55. Rutjes NW, Binnington BA, Smith CR, Maloney MD, Lingwood CA. Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model. Kidney Int. 2002 Sep; 62(3):832-45. PMID: 12164865.
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    56. Binnington B, Lingwood D, Nutikka A, Lingwood CA. Effect of globotriaosyl ceramide fatty acid alpha-hydroxylation on the binding by verotoxin 1 and verotoxin 2. Neurochem Res. 2002 Aug; 27(7-8):807-13. PMID: 12374217.
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    57. Salhia B, Rutka JT, Lingwood C, Nutikka A, Van Furth WR. The treatment of malignant meningioma with verotoxin. Neoplasia. 2002 Jul-Aug; 4(4):304-11. PMID: 12082546.
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    58. Hoey DE, Currie C, Else RW, Nutikka A, Lingwood CA, Gally DL, Smith DG. Expression of receptors for verotoxin 1 from Escherichia coli O157 on bovine intestinal epithelium. J Med Microbiol. 2002 Feb; 51(2):143-9. PMID: 11865842.
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    59. Abul-Milh M, Wu Y, Lau B, Lingwood CA, Barnett Foster D. Induction of epithelial cell death including apoptosis by enteropathogenic Escherichia coli expressing bundle-forming pili. Infect Immun. 2001 Dec; 69(12):7356-64. PMID: 11705908.
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    60. George T, Boyd B, Price M, Lingwood C, Maloney M. MHC class II proteins contain a potential binding site for the verotoxin receptor glycolipid CD77. Cell Mol Biol (Noisy-le-grand). 2001 Nov; 47(7):1179-85. PMID: 11838965.
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    61. Khursigara C, Abul-Milh M, Lau B, Girón JA, Lingwood CA, Barnett Foster DE. Enteropathogenic Escherichia coli virulence factor bundle-forming pilus has a binding specificity for phosphatidylethanolamine. Infect Immun. 2001 Nov; 69(11):6573-9. PMID: 11598024.
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    62. Mamelak D, Mylvaganam M, Tanahashi E, Ito H, Ishida H, Kiso M, Lingwood C. The aglycone of sulfogalactolipids can alter the sulfate ester substitution position required for hsc70 recognition. Carbohydr Res. 2001 Sep 28; 335(2):91-100. PMID: 11567640.
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    63. Facchini LM, Lingwood CA. A verotoxin 1 B subunit-lambda CRO chimeric protein specifically binds both DNA and globotriaosylceramide (Gb(3)) to effect nuclear targeting of exogenous DNA in Gb(3) positive cells. Exp Cell Res. 2001 Sep 10; 269(1):117-29. PMID: 11525645.
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    64. Falguières T, Mallard F, Baron C, Hanau D, Lingwood C, Goud B, Salamero J, Johannes L. Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes. Mol Biol Cell. 2001 Aug; 12(8):2453-68. PMID: 11514628.
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    65. Hartmann E, Lingwood CA, Reidl J. Heat-inducible surface stress protein (Hsp70) mediates sulfatide recognition of the respiratory pathogen Haemophilus influenzae. Infect Immun. 2001 May; 69(5):3438-41. PMID: 11292771.
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    66. Mamelak D, Mylvaganam M, Whetstone H, Hartmann E, Lennarz W, Wyrick PB, Raulston J, Han H, Hoffman P, Lingwood CA. Hsp70s contain a specific sulfogalactolipid binding site. Differential aglycone influence on sulfogalactosyl ceramide binding by recombinant prokaryotic and eukaryotic hsp70 family members. Biochemistry. 2001 Mar 27; 40(12):3572-82. PMID: 11297423.
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    67. Abul-Milh M, Barnett Foster D, Lingwood CA. In vitro binding of Helicobacter pylori to monohexosylceramides. Glycoconj J. 2001 Mar; 18(3):253-60. PMID: 11602809.
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    68. Mamelak D, Lingwood C. The ATPase domain of hsp70 possesses a unique binding specificity for 3'-sulfogalactolipids. J Biol Chem. 2001 Jan 05; 276(1):449-56. PMID: 11024054.
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    69. Arbus GS, Grisaru S, Segal O, Dosch M, Pop M, Lala P, Nutikka A, Lingwood CA. Verotoxin targets lymphoma infiltrates of patients with post-transplant lymphoproliferative disease. Leuk Res. 2000 Oct; 24(10):857-64. PMID: 10996204.
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    70. Peter MG, Lingwood CA. Apparent cooperativity in multivalent verotoxin-globotriaosyl ceramide binding: kinetic and saturation binding studies with [(125)I]verotoxin. Biochim Biophys Acta. 2000 Jun 15; 1501(2-3):116-24. PMID: 10838185.
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    71. Barnett Foster D, Abul-Milh M, Huesca M, Lingwood CA. Enterohemorrhagic Escherichia coli induces apoptosis which augments bacterial binding and phosphatidylethanolamine exposure on the plasma membrane outer leaflet. Infect Immun. 2000 Jun; 68(6):3108-15. PMID: 10816451.
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    72. Lala P, Ito S, Lingwood CA. Retroviral transfection of Madin-Darby canine kidney cells with human MDR1 results in a major increase in globotriaosylceramide and 10(5)- to 10(6)-fold increased cell sensitivity to verocytotoxin. Role of p-glycoprotein in glycolipid synthesis. J Biol Chem. 2000 Mar 03; 275(9):6246-51. PMID: 10692420.
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    73. Abe A, Arend LJ, Lee L, Lingwood C, Brady RO, Shayman JA. Glycosphingolipid depletion in fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase. Kidney Int. 2000 Feb; 57(2):446-54. PMID: 10652021.
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    74. Lingwood CA, Boyd B, Nutikka A. Analysis of interactions between glycosphingolipids and microbial toxins. Methods Enzymol. 2000; 312:459-73. PMID: 11070894.
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    75. Mylvaganam M, Lingwood CA. Oxidation of aglycone of glycosphingolipids: serine and ceramide acid precursors for soluble glycoconjugates. Methods Enzymol. 2000; 312:473-87. PMID: 11070895.
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    76. Khine AA, Lingwood CA. Functional significance of globotriaosyl ceramide in interferon-alpha(2)/type 1 interferon receptor-mediated antiviral activity. J Cell Physiol. 2000 Jan; 182(1):97-108. PMID: 10567921.
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    77. Maloney MD, Binnington-Boyd B, Lingwood CA. Globotriaosyl ceramide modulates interferon-alpha-induced growth inhibition and CD19 expression in Burkitt's lymphoma cells. Glycoconj J. 1999 Dec; 16(12):821-8. PMID: 11133022.
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    78. Arya P, Kutterer KM, Qin H, Roby J, Barnes ML, Lin S, Lingwood CA, Peter MG. Alpha-galactose based neoglycopeptides. Inhibition of verotoxin binding to globotriosylceramide. Bioorg Med Chem. 1999 Dec; 7(12):2823-33. PMID: 10658586.
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    79. Barnett Foster D, Philpott D, Abul-Milh M, Huesca M, Sherman PM, Lingwood CA. Phosphatidylethanolamine recognition promotes enteropathogenic E. coli and enterohemorrhagic E. coli host cell attachment. Microb Pathog. 1999 Nov; 27(5):289-301. PMID: 10545256.
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    80. Lingwood CA. Glycolipid receptors for verotoxin and Helicobacter pylori: role in pathology. Biochim Biophys Acta. 1999 Oct 08; 1455(2-3):375-86. PMID: 10571026.
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    81. Lingwood CA. Verotoxin/globotriaosyl ceramide recognition: angiopathy, angiogenesis and antineoplasia. Biosci Rep. 1999 Oct; 19(5):345-54. PMID: 10763802.
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    82. Mylvaganam M, Meng L, Lingwood CA. Oxidation of glycosphingolipids under basic conditions: synthesis of glycosyl "serine acids" as opposed to "ceramide acids". Precursors for neoglycoconjugates with increased ligand binding affinity. Biochemistry. 1999 Aug 17; 38(33):10885-97. PMID: 10451385.
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    83. Mylvaganam M, Lingwood CA. A convenient oxidation of natural glycosphingolipids to their "ceramide acids" for neoglycoconjugation. Bovine serum albumin-glycosylceramide acid conjugates as investigative probes for HIV gp120 coat protein-glycosphingolipid interactions. J Biol Chem. 1999 Jul 16; 274(29):20725-32. PMID: 10400707.
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    84. Deka RK, Lee YH, Hagman KE, Shevchenko D, Lingwood CA, Hasemann CA, Norgard MV, Radolf JD. Physicochemical evidence that Treponema pallidum TroA is a zinc-containing metalloprotein that lacks porin-like structure. J Bacteriol. 1999 Jul; 181(14):4420-3. PMID: 10400603.
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    85. Picking WD, McCann JA, Nutikka A, Lingwood CA. Localization of the binding site for modified Gb3 on verotoxin 1 using fluorescence analysis. Biochemistry. 1999 Jun 01; 38(22):7177-84. PMID: 10353828.
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    86. Mylvaganam M, Lingwood CA. Adamantyl globotriaosyl ceramide: a monovalent soluble mimic which inhibits verotoxin binding to its glycolipid receptor. Biochem Biophys Res Commun. 1999 Apr 13; 257(2):391-4. PMID: 10198223.
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    87. Williams JM, Boyd B, Nutikka A, Lingwood CA, Barnett Foster DE, Milford DV, Taylor CM. A comparison of the effects of verocytotoxin-1 on primary human renal cell cultures. Toxicol Lett. 1999 Mar 08; 105(1):47-57. PMID: 10092056.
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    88. Liu XH, Lingwood CA, Ray PE. Recruitment of renal tubular epithelial cells expressing verotoxin-1 (Stx1) receptors in HIV-1 transgenic mice with renal disease. Kidney Int. 1999 Feb; 55(2):554-61. PMID: 9987079.
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    89. Arab S, Rutka J, Lingwood C. Verotoxin induces apoptosis and the complete, rapid, long-term elimination of human astrocytoma xenografts in nude mice. Oncol Res. 1999; 11(1):33-9. PMID: 10451029.
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    90. Arab S, Lingwood CA. Intracellular targeting of the endoplasmic reticulum/nuclear envelope by retrograde transport may determine cell hypersensitivity to verotoxin via globotriaosyl ceramide fatty acid isoform traffic. J Cell Physiol. 1998 Dec; 177(4):646-60. PMID: 10092217.
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    91. Lingwood CA. Oligosaccharide receptors for bacteria: a view to a kill. Curr Opin Chem Biol. 1998 Dec; 2(6):695-700. PMID: 9914190.
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    92. Arab S, Murakami M, Dirks P, Boyd B, Hubbard SL, Lingwood CA, Rutka JT. Verotoxins inhibit the growth of and induce apoptosis in human astrocytoma cells. J Neurooncol. 1998 Nov; 40(2):137-50. PMID: 9892096.
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    93. Huesca M, Goodwin A, Bhagwansingh A, Hoffman P, Lingwood CA. Characterization of an acidic-pH-inducible stress protein (hsp70), a putative sulfatide binding adhesin, from Helicobacter pylori. Infect Immun. 1998 Sep; 66(9):4061-7. PMID: 9712748.
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    94. Khine AA, Firtel M, Lingwood CA. CD77-dependent retrograde transport of CD19 to the nuclear membrane: functional relationship between CD77 and CD19 during germinal center B-cell apoptosis. J Cell Physiol. 1998 Aug; 176(2):281-92. PMID: 9648915.
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    95. Lu D, Boyd B, Lingwood CA. The expression and characterization of a putative adhesin B from H. influenzae. FEMS Microbiol Lett. 1998 Aug 01; 165(1):129-37. PMID: 9711849.
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    96. Bitzan MM, Gold BD, Philpott DJ, Huesca M, Sherman PM, Karch H, Lissner R, Lingwood CA, Karmali MA. Inhibition of Helicobacter pylori and Helicobacter mustelae binding to lipid receptors by bovine colostrum. J Infect Dis. 1998 Apr; 177(4):955-61. PMID: 9534968.
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    97. Kim JH, Johannes L, Goud B, Antony C, Lingwood CA, Daneman R, Grinstein S. Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2997-3002. PMID: 9501204.
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    98. Tanphaichitr N, Moase C, Taylor T, Surewicz K, Hansen C, Namking M, Bérubé B, Kamolvarin N, Lingwood CA, Sullivan R, Rattanachaiyanont M, White D. Isolation of antiSLIP1-reactive boar sperm P68/62 and its binding to mammalian zona pellucida. Mol Reprod Dev. 1998 Feb; 49(2):203-16. PMID: 9444663.
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    99. Schapiro FB, Lingwood C, Furuya W, Grinstein S. pH-independent retrograde targeting of glycolipids to the Golgi complex. Am J Physiol. 1998 02; 274(2):C319-32. PMID: 9486120.
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    100. Lingwood CA, Khine AA, Arab S. Globotriaosyl ceramide (Gb3) expression in human tumour cells: intracellular trafficking defines a new retrograde transport pathway from the cell surface to the nucleus, which correlates with sensitivity to verotoxin. Acta Biochim Pol. 1998; 45(2):351-9. PMID: 9821866.
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    101. Lu D, Boyd B, Lingwood CA. Identification of the key protein for zinc uptake in Hemophilus influenzae. J Biol Chem. 1997 Nov 14; 272(46):29033-8. PMID: 9360976.
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    102. Mamelak D, Lingwood C. Expression and sulfogalactolipid binding specificity of the recombinant testis-specific cognate heat shock protein 70. Glycoconj J. 1997 Sep; 14(6):715-22. PMID: 9337084.
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    103. Jones DH, Lingwood CA, Barber KR, Grant CW. Globoside as a membrane receptor: a consideration of oligosaccharide communication with the hydrophobic domain. Biochemistry. 1997 Jul 15; 36(28):8539-47. PMID: 9214299.
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    104. Hartmann E, Lingwood C. Brief heat shock treatment induces a long-lasting alteration in the glycolipid receptor binding specificity and growth rate of Haemophilus influenzae. Infect Immun. 1997 May; 65(5):1729-33. PMID: 9125554.
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    105. Busse J, Hartmann E, Lingwood CA. Receptor affinity purification of a lipid-binding adhesin from Haemophilus influenzae. J Infect Dis. 1997 Jan; 175(1):77-83. PMID: 8985199.
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    106. Arab S, Russel E, Chapman WB, Rosen B, Lingwood CA. Expression of the verotoxin receptor glycolipid, globotriaosylceramide, in ovarian hyperplasias. Oncol Res. 1997; 9(10):553-63. PMID: 9507533.
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    107. Valdivieso-Garcia A, MacLeod DL, Clarke RC, Gyles CL, Lingwood C, Boyd B, Durette A. Comparative cytotoxicity of purified Shiga-like toxin-IIe on porcine and bovine aortic endothelial and human colonic adenocarcinoma cells. J Med Microbiol. 1996 Nov; 45(5):331-7. PMID: 8918947.
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    108. Kim JH, Lingwood CA, Williams DB, Furuya W, Manolson MF, Grinstein S. Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor. J Cell Biol. 1996 Sep; 134(6):1387-99. PMID: 8830769.
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    109. Lingwood CA. Aglycone modulation of glycolipid receptor function. Glycoconj J. 1996 Aug; 13(4):495-503. PMID: 8872104.
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    110. Huesca M, Borgia S, Hoffman P, Lingwood CA. Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization. Infect Immun. 1996 Jul; 64(7):2643-8. PMID: 8698490.
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    111. Waddell TE, Lingwood CA, Gyles CL. Interaction of verotoxin 2e with pig intestine. Infect Immun. 1996 May; 64(5):1714-9. PMID: 8613382.
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    112. Lingwood CA. Role of verotoxin receptors in pathogenesis. Trends Microbiol. 1996 Apr; 4(4):147-53. PMID: 8728608.
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    113. Arab S, Lingwood CA. Influence of phospholipid chain length on verotoxin/globotriaosyl ceramide binding in model membranes: comparison of a supported bilayer film and liposomes. Glycoconj J. 1996 Apr; 13(2):159-66. PMID: 8737240.
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    114. Nyholm PG, Magnusson G, Zheng Z, Norel R, Binnington-Boyd B, Lingwood CA. Two distinct binding sites for globotriaosyl ceramide on verotoxins: identification by molecular modelling and confirmation using deoxy analogues and a new glycolipid receptor for all verotoxins. Chem Biol. 1996 Apr; 3(4):263-75. PMID: 8807854.
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    115. Robinson LA, Hurley RM, Lingwood C, Matsell DG. Escherichia coli verotoxin binding to human paediatric glomerular mesangial cells. Pediatr Nephrol. 1995 Dec; 9(6):700-4. PMID: 8747108.
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    116. Boulanger J, Faulds D, Eddy EM, Lingwood CA. Members of the 70 kDa heat shock protein family specifically recognize sulfoglycolipids: role in gamete recognition and mycoplasma-related infertility. J Cell Physiol. 1995 Oct; 165(1):7-17. PMID: 7559808.
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    117. Gold BD, Dytoc M, Huesca M, Philpott D, Kuksis A, Czinn S, Lingwood CA, Sherman PM. Comparison of Helicobacter mustelae and Helicobacter pylori adhesion to eukaryotic cells in vitro. Gastroenterology. 1995 Sep; 109(3):692-700. PMID: 7657097.
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    118. Farkas-Himsley H, Hill R, Rosen B, Arab S, Lingwood CA. The bacterial colicin active against tumor cells in vitro and in vivo is verotoxin 1. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):6996-7000. PMID: 7624357.
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    119. Louise CB, Kaye SA, Boyd B, Lingwood CA, Obrig TG. Shiga toxin-associated hemolytic uremic syndrome: effect of sodium butyrate on sensitivity of human umbilical vein endothelial cells to Shiga toxin. Infect Immun. 1995 Jul; 63(7):2766-9. PMID: 7790096.
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    120. Nyholm PG, Brunton JL, Lingwood CA. Modelling of the interaction of verotoxin-1 (VT1) with its glycolipid receptor, globotriaosylceramide (Gb3). Int J Biol Macromol. 1995 Jun; 17(3-4):199-204. PMID: 7577818.
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    121. Khine AA, Lingwood CA. Capping and receptor-mediated endocytosis of cell-bound verotoxin (Shiga-like toxin). 1: Chemical identification of an amino acid in the B subunit necessary for efficient receptor glycolipid binding and cellular internalization. J Cell Physiol. 1994 Nov; 161(2):319-32. PMID: 7962116.
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    122. Ghislain J, Lingwood CA, Fish EN. Evidence for glycosphingolipid modification of the type 1 IFN receptor. J Immunol. 1994 Oct 15; 153(8):3655-63. PMID: 7930586.
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    123. Boyd B, Magnusson G, Zhiuyan Z, Lingwood CA. Lipid modulation of glycolipid receptor function. Availability of Gal(alpha 1-4)Gal disaccharide for verotoxin binding in natural and synthetic glycolipids. Eur J Biochem. 1994 Aug 01; 223(3):873-8. PMID: 8055965.
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    124. Maloney MD, Lingwood CA. CD19 has a potential CD77 (globotriaosyl ceramide)-binding site with sequence similarity to verotoxin B-subunits: implications of molecular mimicry for B cell adhesion and enterohemorrhagic Escherichia coli pathogenesis. J Exp Med. 1994 Jul 01; 180(1):191-201. PMID: 7516406.
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    125. Kiarash A, Boyd B, Lingwood CA. Glycosphingolipid receptor function is modified by fatty acid content. Verotoxin 1 and verotoxin 2c preferentially recognize different globotriaosyl ceramide fatty acid homologues. J Biol Chem. 1994 Apr 15; 269(15):11138-46. PMID: 8157640.
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    126. Lingwood CA, Sakac D, Saltiel A. Developmentally regulated testicular galactolipid sulfotransferase inhibitor is a phosphoinositol glycerolipid and insulin-mimetic. Mol Reprod Dev. 1994 Apr; 37(4):462-6. PMID: 8011331.
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    127. Boulanger J, Huesca M, Arab S, Lingwood CA. Universal method for the facile production of glycolipid/lipid matrices for the affinity purification of binding ligands. Anal Biochem. 1994 Feb 15; 217(1):1-6. PMID: 8203724.
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    128. Lingwood CA, Nutikka A. A novel chemical procedure for the selective removal of nonreducing terminal N-acetyl hexosamine residues from glycolipids. Anal Biochem. 1994 Feb 15; 217(1):119-23. PMID: 8203726.
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    129. Lee KK, Sheth HB, Wong WY, Sherburne R, Paranchych W, Hodges RS, Lingwood CA, Krivan H, Irvin RT. The binding of Pseudomonas aeruginosa pili to glycosphingolipids is a tip-associated event involving the C-terminal region of the structural pilin subunit. Mol Microbiol. 1994 Feb; 11(4):705-13. PMID: 7910938.
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    130. Pereira J, Boyd B, Newbigging J, Lingwood C, Strasberg PM. Increased globotriaosylceramide on plasma membranes of synchronized familial dysautonomia cells. Verotoxin binding studies. J Mol Neurosci. 1994; 5(2):121-32. PMID: 7710921.
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    131. Lingwood CA. Verotoxin-binding in human renal sections. Nephron. 1994; 66(1):21-8. PMID: 8107950.
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    132. Mangeney M, Lingwood CA, Taga S, Caillou B, Tursz T, Wiels J. Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen. Cancer Res. 1993 Nov 01; 53(21):5314-9. PMID: 8221667.
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    133. Huesca M, Gold B, Sherman P, Lewin P, Lingwood C. Therapeutics used to alleviate peptic ulcers inhibit H. pylori receptor binding in vitro. Zentralbl Bakteriol. 1993 Sep; 280(1-2):244-52. PMID: 8280948.
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    134. Kaye SA, Louise CB, Boyd B, Lingwood CA, Obrig TG. Shiga toxin-associated hemolytic uremic syndrome: interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro. Infect Immun. 1993 Sep; 61(9):3886-91. PMID: 8359910.
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    135. Obrig TG, Louise CB, Lingwood CA, Boyd B, Barley-Maloney L, Daniel TO. Endothelial heterogeneity in Shiga toxin receptors and responses. J Biol Chem. 1993 Jul 25; 268(21):15484-8. PMID: 8340376.
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    136. Boyd B, Tyrrell G, Maloney M, Gyles C, Brunton J, Lingwood C. Alteration of the glycolipid binding specificity of the pig edema toxin from globotetraosyl to globotriaosyl ceramide alters in vivo tissue targetting and results in a verotoxin 1-like disease in pigs. J Exp Med. 1993 Jun 01; 177(6):1745-53. PMID: 8496689.
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    137. Lingwood CA, Wasfy G, Han H, Huesca M. Receptor affinity purification of a lipid-binding adhesin from Helicobacter pylori. Infect Immun. 1993 Jun; 61(6):2474-8. PMID: 8500882.
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    138. Gold BD, Huesca M, Sherman PM, Lingwood CA. Helicobacter mustelae and Helicobacter pylori bind to common lipid receptors in vitro. Infect Immun. 1993 Jun; 61(6):2632-8. PMID: 8500901.
      View in: PubMed
    139. Tanphaichitr N, Smith J, Mongkolsirikieart S, Gradil C, Lingwood CA. Role of a gamete-specific sulfoglycolipid immobilizing protein on mouse sperm-egg binding. Dev Biol. 1993 Mar; 156(1):164-75. PMID: 8449366.
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    140. Dytoc M, Gold B, Louie M, Huesca M, Fedorko L, Crowe S, Lingwood C, Brunton J, Sherman P. Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells. Infect Immun. 1993 Feb; 61(2):448-56. PMID: 8380793.
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    141. Lingwood CA. Verotoxins and their glycolipid receptors. Adv Lipid Res. 1993; 25:189-211. PMID: 8368148.
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    142. Zoja C, Corna D, Farina C, Sacchi G, Lingwood C, Doyle MP, Padhye VV, Abbate M, Remuzzi G. Verotoxin glycolipid receptors determine the localization of microangiopathic process in rabbits given verotoxin-1. J Lab Clin Med. 1992 Aug; 120(2):229-38. PMID: 1323633.
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    143. Lingwood CA, Huesca M, Kuksis A. The glycerolipid receptor for Helicobacter pylori (and exoenzyme S) is phosphatidylethanolamine. Infect Immun. 1992 Jun; 60(6):2470-4. PMID: 1587616.
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    144. Tanphaichitr N, Tayabali A, Gradil C, Juneja S, Léveillé MC, Lingwood CA. Role of a germ cell-specific sulfolipid-immobilizing protein (SLIP1) in mouse in vivo fertilization. Mol Reprod Dev. 1992 May; 32(1):17-22. PMID: 1515145.
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    145. Lingwood CA, Yiu SK. Glycolipid modification of alpha 2 interferon binding. Sequence similarity between the alpha 2 interferon receptor and verotoxin (Shiga-like toxin) B-subunit. Biochem J. 1992 Apr 01; 283 ( Pt 1):25-6. PMID: 1314564.
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    146. Yiu SC, Lingwood CA. Polyisobutylmethacrylate modifies glycolipid binding specificity of verotoxin 1 in thin-layer chromatogram overlay procedures. Anal Biochem. 1992 Apr; 202(1):188-92. PMID: 1621981.
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    147. Pudymaitis A, Lingwood CA. Susceptibility to verotoxin as a function of the cell cycle. J Cell Physiol. 1992 Mar; 150(3):632-9. PMID: 1537890.
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    148. Pellizzari A, Pang H, Lingwood CA. Binding of verocytotoxin 1 to its receptor is influenced by differences in receptor fatty acid content. Biochemistry. 1992 Feb 11; 31(5):1363-70. PMID: 1310610.
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    149. Sakac D, Zachos M, Lingwood CA. Purification of the testicular galactolipid: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase. J Biol Chem. 1992 Jan 25; 267(3):1655-9. PMID: 1730710.
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    150. Tyrrell GJ, Ramotar K, Toye B, Boyd B, Lingwood CA, Brunton JL. Alteration of the carbohydrate binding specificity of verotoxins from Gal alpha 1-4Gal to GalNAc beta 1-3Gal alpha 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit. Proc Natl Acad Sci U S A. 1992 Jan 15; 89(2):524-8. PMID: 1731324.
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    151. Nutikka A, Pang H, Soldin S, Lingwood C. Synthesis and structural characterization of a cardioactive biotinylated digoxin analogue. Clin Biochem. 1991 Dec; 24(6):469-73. PMID: 1773486.
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    152. Pudymaitis A, Armstrong G, Lingwood CA. Verotoxin-resistant cell clones are deficient in the glycolipid globotriosylceramide: differential basis of phenotype. Arch Biochem Biophys. 1991 May 01; 286(2):448-52. PMID: 1910293.
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    153. Krivan HC, Nilsson B, Lingwood CA, Ryu H. Chlamydia trachomatis and Chlamydia pneumoniae bind specifically to phosphatidylethanolamine in HeLa cells and to GalNAc beta 1-4Gal beta 1-4GLC sequences-found in asialo-GM1 and asial-GM2. Biochem Biophys Res Commun. 1991 Mar 29; 175(3):1082-9. PMID: 2025240.
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    154. Lingwood CA, Cheng M, Krivan HC, Woods D. Glycolipid receptor binding specificity of exoenzyme S from Pseudomonas aeruginosa. Biochem Biophys Res Commun. 1991 Mar 29; 175(3):1076-81. PMID: 1902668.
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    155. Head SC, Karmali MA, Lingwood CA. Preparation of VT1 and VT2 hybrid toxins from their purified dissociated subunits. Evidence for B subunit modulation of a subunit function. J Biol Chem. 1991 Feb 25; 266(6):3617-21. PMID: 1847382.
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    156. Lingwood C, Nutikka A. Studies on the spermatogenic sulfogalactolipid binding protein SLIP 1. J Cell Physiol. 1991 Feb; 146(2):258-63. PMID: 1999474.
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    157. Ramotar K, Boyd B, Tyrrell G, Gariepy J, Lingwood C, Brunton J. Characterization of Shiga-like toxin I B subunit purified from overproducing clones of the SLT-I B cistron. Biochem J. 1990 Dec 15; 272(3):805-11. PMID: 2268304.
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    158. Boulanger J, Petric M, Lingwood C, Law H, Roscoe M, Karmali M. Neutralization receptor-based immunoassay for detection of neutralizing antibodies to Escherichia coli verocytotoxin 1. J Clin Microbiol. 1990 Dec; 28(12):2830-3. PMID: 2280020.
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    159. Lingwood CA, Quinn PA, Wilansky S, Nutikka A, Ruhnke HL, Miller RB. Common sulfoglycolipid receptor for mycoplasmas involved in animal and human infertility. Biol Reprod. 1990 Oct; 43(4):694-7. PMID: 2289018.
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    160. Waddell T, Cohen A, Lingwood CA. Induction of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriosylceramide. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):7898-901. PMID: 2236008.
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    161. Head S, Ramotar K, Lingwood C. Modification of the glycolipid-binding specificity of vero cytotoxin by polymyxin B and other cyclic amphipathic peptides. Infect Immun. 1990 Jun; 58(6):1532-7. PMID: 2160427.
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    162. Cohen A, Madrid-Marina V, Estrov Z, Freedman MH, Lingwood CA, Dosch HM. Expression of glycolipid receptors to Shiga-like toxin on human B lymphocytes: a mechanism for the failure of long-lived antibody response to dysenteric disease. Int Immunol. 1990; 2(1):1-8. PMID: 1965141.
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    163. Lingwood C, Schramayr S, Quinn P. Male germ cell specific sulfogalactoglycerolipid is recognized and degraded by mycoplasmas associated with male infertility. J Cell Physiol. 1990 Jan; 142(1):170-6. PMID: 2298820.
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    164. Lingwood CA, Law H, Pellizzari A, Sherman P, Drumm B. Gastric glycerolipid as a receptor for Campylobacter pylori. Lancet. 1989 Jul 29; 2(8657):238-41. PMID: 2569053.
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    165. DeGrandis S, Law H, Brunton J, Gyles C, Lingwood CA. Globotetraosylceramide is recognized by the pig edema disease toxin. J Biol Chem. 1989 Jul 25; 264(21):12520-5. PMID: 2663859.
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    166. Sakac D, Lingwood CA. Modulation of testicular galactolipid sulphotransferase activity by phosphorylation. Stimulation of enzyme activity in vitro by an endogenous kinase. Biochem J. 1989 Jul 15; 261(2):423-9. PMID: 2775226.
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    167. Basta M, Karmali M, Lingwood C. Sensitive receptor-specified enzyme-linked immunosorbent assay for Escherichia coli verocytotoxin. J Clin Microbiol. 1989 Jul; 27(7):1617-22. PMID: 2671020.
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    168. Boyd B, Lingwood C. Verotoxin receptor glycolipid in human renal tissue. Nephron. 1989; 51(2):207-10. PMID: 2644572.
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    169. Law H, Itkonnen O, Lingwood CA. Sulfogalactolipid binding protein SLIP 1: a conserved function for a conserved protein. J Cell Physiol. 1988 Dec; 137(3):462-8. PMID: 3192627.
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    170. Waddell T, Head S, Petric M, Cohen A, Lingwood C. Globotriosyl ceramide is specifically recognized by the Escherichia coli verocytotoxin 2. Biochem Biophys Res Commun. 1988 Apr 29; 152(2):674-9. PMID: 3284526.
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    171. Cohen A, Hannigan GE, Williams BR, Lingwood CA. Roles of globotriosyl- and galabiosylceramide in verotoxin binding and high affinity interferon receptor. J Biol Chem. 1987 Dec 15; 262(35):17088-91. PMID: 2824515.
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    172. Lingwood CA, Law H, Richardson S, Petric M, Brunton JL, De Grandis S, Karmali M. Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro. J Biol Chem. 1987 Jun 25; 262(18):8834-9. PMID: 3298243.
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    173. Taylor T, Oda K, Lingwood C. Modulation of testicular galactolipid sulfotransferase activity in vitro by ATP. Biochim Biophys Acta. 1987 Jun 17; 913(2):131-7. PMID: 3036232.
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    174. Lingwood CA. Colocalization of sulfogalactosylacylalkylglycerol (SGG) and its binding protein during spermatogenesis and sperm maturation. Topology of SGG defines a new testicular germ cell membrane domain. Biochem Cell Biol. 1986 Oct; 64(10):984-92. PMID: 3541976.
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    175. Lingwood C, Taylor T. Synthesis and use of galactolipid sulfotransferase substrate-analogue affinity probes: possible localization of the testicular enzyme. Biochem Cell Biol. 1986 Jul; 64(7):631-7. PMID: 3463330.
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    176. Lingwood CA, Dennis J, Hsu E, Sakac D, Oda K, Strasberg P, Taylor T, Warren I, Yeger H, Baumal R. Regulation of renal sulfoglycolipid biosynthesis. Biochim Biophys Acta. 1986 Jun 27; 877(2):246-51. PMID: 3459553.
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    177. Lingwood CA. Developmental regulation of galactoglycerolipid and galactosphingolipid sulphation during mammalian spermatogenesis. Evidence for a substrate-selective inhibitor of testicular sulphotransferase activity in the rat. Biochem J. 1985 Oct 15; 231(2):393-400. PMID: 3864440.
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    178. Lingwood C, Kunz HW, Gill TJ. Deficiency in the regulation of testicular galactolipid sulphotransferase in rats carrying the growth-and-reproduction-complex (grc) gene. Biochem J. 1985 Oct 15; 231(2):401-5. PMID: 3864441.
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    179. Lingwood CA. Protein-glycolipid interactions during spermatogenesis. Binding of specific germ cell proteins to sulfatoxygalactosylacylalkylglycerol, the major glycolipid of mammalian male germ cells. Can J Biochem Cell Biol. 1985 Oct; 63(10):1077-85. PMID: 3907802.
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    180. Thong B, Soldin SJ, Lingwood CA. Lack of specificity of current anti-digoxin antibodies, and preparation of a new, specific polyclonal antibody that recognizes the carbohydrate moiety of digoxin. Clin Chem. 1985 Oct; 31(10):1625-31. PMID: 4042328.
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    181. Law H, Lingwood CA. Use of fluorescent standards in protein transfer and immunoblotting. Accurate estimation of the molecular weight of immunoreactive species. Anal Biochem. 1985 Sep; 149(2):404-8. PMID: 3935006.
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    182. Eddy EM, Muller CH, Lingwood CA. Preparation of monoclonal antibody to sulfatoxygalactosylglycerolipid by in vitro immunization with a glycolipid-glass conjugate. J Immunol Methods. 1985 Jul 16; 81(1):137-46. PMID: 4020146.
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    183. Lingwood CA. Timing of sulphogalactolipid biosynthesis in the rat testis studied by tissue autoradiography. J Cell Sci. 1985 Apr; 75:329-38. PMID: 4044678.
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    184. Soldin SJ, Papanastasiou-Diamandi A, Heyes J, Lingwood C, Olley P. Are immunoassays for digoxin reliable? Clin Biochem. 1984 Oct; 17(5):317-20. PMID: 6499162.
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    185. Lingwood CA. Production of glycolipid affinity matrices by use of heterobifunctional crosslinking agents. J Lipid Res. 1984 Sep; 25(9):1010-2. PMID: 6491535.
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    186. Lingwood C, Hay G, Schachter H. Tissue distribution of sulfolipids in the rat. Restricted location of sulfatoxygalactosylacylalkylglycerol. Can J Biochem. 1981 Jul; 59(7):556-63. PMID: 7028219.
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    187. Lingwood C, Schachter H. Localization of sulfatoxygalactosylacylalkylglycerol at the surface of rat testicular germinal cells by immunocytochemical techniques: pH dependence of a nonimmunological reaction between immunoglobulin and germinal cells. J Cell Biol. 1981 Jun; 89(3):621-30. PMID: 7019217.
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    188. Lingwood CA, Hakomori S, Ji TH. A glycolipid and its associated proteins: evidence by crosslinking of human erythrocyte surface components. FEBS Lett. 1980 Apr 07; 112(2):265-8. PMID: 7371864.
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    189. Lingwood CA, Murray RK, Schachter H. The preparation of rabbit antiserum specific for mammalian testicular sulfogalactoglycerolipid. J Immunol. 1980 Feb; 124(2):769-74. PMID: 7356712.
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    190. Hakomori S, Young WW, Patt LM, Yoshino T, Halfpap L, Lingwood CA. Cell biological and immunological significance of ganglioside changes associated with transformation. Adv Exp Med Biol. 1980; 125:247-61. PMID: 6244722.
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    191. Lingwood CA. Action of galactose oxidase on galactolipids. Can J Biochem. 1979 Sep; 57(9):1138-43. PMID: 509355.
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    192. Lingwood CA, Ng A, Hakomori S. Monovalent antibodies directed to transformation-sensitive membrane components inhibit the process of viral transformation. Proc Natl Acad Sci U S A. 1978 Dec; 75(12):6049-53. PMID: 216010.
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    193. Carter WG, Fukuda M, Lingwood C, Hakomori S. Chemical composition, gross structure, and organization of transformation-sensitive glycoproteins. Ann N Y Acad Sci. 1978 Jun 20; 312:160-77. PMID: 291360.
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    194. Lingwood CA, Hakomori S. Selective inhibition of cell growth and associated changes in glycolipid metabolism induced by monovalent antibodies to glycolipids. Exp Cell Res. 1977 Sep; 108(2):385-91. PMID: 891645.
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    195. Lingwood CA, Thomas DB. Modulation in the rates of incorporation of lipid precursors during the cell cycle. J Cell Physiol. 1975 Dec; 86 Suppl 2(3 Pt 2):635-40. PMID: 1202038.
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    196. Thomas DB, Lingwood CA. A model of cell cycle control: effects of thymidine on synchronous cell cultures. Cell. 1975 May; 5(1):37-42. PMID: 124211.
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    197. Lingwood CA, Thomas DB. Rapid changes in nucleoside transport induced by growth inhibitors. Studies with neoplastic mast cells. J Cell Biol. 1974 May; 61(2):359-68. PMID: 4363956.
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    198. Lingwood CA, Thomas DB. A one cell-cycle delay for tumor cytostasis in vitro: effects of dibutyryl cyclic AMP or embryonic extracts on synchronized cultures of a murine tumor. J Natl Cancer Inst. 1974 May; 52(5):1659-64. PMID: 4364741.
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    199. Thomas DB, Medley G, Lingwood CA. Growth inhibition of murine tumor cells, in vitro, by puromycin, ( 6 N)O 2 '-dibutyryl 3',5'-adenosine monophosphate, or adenosine: evidence of commitment for cell division. J Cell Biol. 1973 May; 57(2):397-405. PMID: 4348788.
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