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Hiroshi Otsubo

TitleDirector, Neurophysiology Lab
InstitutionThe Hospital for Sick Children
DepartmentNeurology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mata-Mbemba D, Iimura Y, Hazrati LN, Ochi A, Otsubo H, Snead OC, Rutka J, Widjaja E. MRI, Magnetoencephalography, and Surgical Outcome of Oligodendrocytosis versus Focal Cortical Dysplasia Type I. AJNR Am J Neuroradiol. 2018 Nov 15. PMID: 30442696.
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    2. Jalloh I, Cho N, Nga VDW, Whitney R, Jain P, Al-Mehmadi S, Yau I, Okura H, Widjaja E, Otsubo H, Ochi A, Donner E, McCoy B, Drake J, Go C, Rutka JT. The role of surgery in refractory epilepsy secondary to polymicrogyria in the pediatric population. Epilepsia. 2018 Oct; 59(10):1982-1996. PMID: 30203507.
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    3. Jain P, Whitney R, Strantzas S, McCoy B, Ochi A, Otsubo H, Snead OC, Weiss S, Donner E, Pang E, Sharma R, Viljoen A, Keller A, Drake JM, Rutka JT, Go C. Intra-operative cortical motor mapping using subdural grid electrodes in children undergoing epilepsy surgery evaluation and comparison with the conventional extra-operative motor mapping. Clin Neurophysiol. 2018 Aug 12. PMID: 30150028.
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    4. Morrison-Levy N, Go C, Ochi A, Otsubo H, Drake J, Rutka J, Weiss SK. Children with autism spectrum disorders and drug-resistant epilepsy can benefit from epilepsy surgery. Epilepsy Behav. 2018 Aug; 85:200-204. PMID: 30032808.
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    5. Gulati P, Jain P, Qashqari H, Bradbury L, Cooper P, Otsubo H, Whitney R. Peri-oral myoclonia with absences with multiple facial and upper body myoclonia: Overlap epilepsy syndrome. J Clin Neurosci. 2018 Aug; 54:135-137. PMID: 29907391.
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    6. Jain P, Shafi S, Ochi A, Donner E, Sharma R, Ibrahim G, Drake J, Otsubo H. High voltage 14?Hz hippocampal discharges on stereotactic EEG underlying 14&6?Hz positive bursts on scalp EEG. Clin Neurophysiol. 2018 Aug; 129(8):1626-1627. PMID: 29906779.
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    7. Nakajima M, Wong S, Widjaja E, Baba S, Okanishi T, Takada L, Sato Y, Iwata H, Sogabe M, Morooka H, Whitney R, Ueda Y, Ito T, Yagyu K, Ochi A, Carter Snead O, Rutka JT, Drake JM, Doesburg S, Takeuchi F, Shiraishi H, Otsubo H. Advanced dynamic statistical parametric mapping with MEG in localizing epileptogenicity of the bottom of sulcus dysplasia. Clin Neurophysiol. 2018 Jun; 129(6):1182-1191. PMID: 29649770.
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    8. Nishimura M, Okanishi T, Fujimoto A, Kanai S, Sasaki Y, Homma Y, Otsubo H, Enoki H. Three phase-ictal scalp EEG patterns in patients with seizures arising from the cortex facing the interhemispheric fissure. Epilepsy Res. 2018 07; 143:105-112. PMID: 29475788.
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    9. Iimura Y, Jones K, Takada L, Shimizu I, Koyama M, Hattori K, Okazawa Y, Nonoda Y, Asano E, Akiyama T, Go C, Ochi A, Snead OC, Donner EJ, Rutka JT, Drake JM, Otsubo H. Strong coupling between slow oscillations and wide fast ripples in children with epileptic spasms: Investigation of modulation index and occurrence rate. Epilepsia. 2018 03; 59(3):544-554. PMID: 29315516.
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    10. Inoue T, Kawawaki H, Fukuoka M, Kim K, Nukui M, Kuki I, Okazaki S, Koh S, Kunihiro N, Uda T, Matsusaka Y, Matsuhashi M, Iimura Y, Otsubo H. Intraoperative cortico-cortical evoked potentials show disconnection of the motor cortex from the epileptogenic network during subtotal hemispherotomy. Clin Neurophysiol. 2017 Dec 23; 129(2):455-457. PMID: 29306848.
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    11. Ahmed R, Otsubo H, Snead C, Donner E, Widjaja E, Ochi A, Drake JM, Rutka JT. Diagnostic evaluation and surgical management of pediatric insular epilepsy utilizing magnetoencephalography and invasive EEG monitoring. Epilepsy Res. 2018 02; 140:72-81. PMID: 29288902.
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    12. Sato Y, Wong SM, Iimura Y, Ochi A, Doesburg SM, Otsubo H. Spatiotemporal changes in regularity of gamma oscillations contribute to focal ictogenesis. Sci Rep. 2017 Aug 24; 7(1):9362. PMID: 28839247.
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    13. Okanari K, Otsubo H, Kouzmitcheva E, Rangrej J, Baba S, Ochi A, Okanishi T, Homma Y, Nita DA, Donner EJ. Ictal Symmetric Tonic Extension Posturing and Postictal Generalized EEG Suppression Arising From Sleep in Children With Epilepsy. Pediatr Neurol. 2017 Nov; 76:54-59. PMID: 28967460.
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    14. Frauscher B, Bartolomei F, Kobayashi K, Cimbalnik J, van 't Klooster MA, Rampp S, Otsubo H, Höller Y, Wu JY, Asano E, Engel J, Kahane P, Jacobs J, Gotman J. High-frequency oscillations: The state of clinical research. Epilepsia. 2017 08; 58(8):1316-1329. PMID: 28666056.
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    15. Iida K, Otsubo H. Stereoelectroencephalography: Indication and Efficacy. Neurol Med Chir (Tokyo). 2017 Aug 15; 57(8):375-385. PMID: 28637943.
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    16. Whitney R, AlMehmadi S, Go C, Ochi A, Otsubo H, Bradbury L, Jones K, Christian E, Rutka J, McCoy B. Spiders, ladybugs and bees: A case of unusual sensations in a child with cingulate epilepsy. Epilepsy Behav Case Rep. 2017; 8:1-6. PMID: 28603689.
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    17. Whitney R, AlMehmadi S, McCoy B, Yau I, Ochi A, Otsubo H, Weiss SK, Rutka J, Hazrati LN, Snead OC, Go C. The Fault in Their Stars-Accumulating Astrocytic Inclusions Associated With Clusters of Epileptic Spasms in Children With Global Developmental Delay. Pediatr Neurol. 2017 Aug; 73:92-97.e3. PMID: 28549652.
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    18. Iimura Y, Jones K, Hattori K, Okazawa Y, Noda A, Hoashi K, Nonoda Y, Asano E, Akiyama T, Go C, Ochi A, Snead OC, Donner EJ, Rutka JT, Drake JM, Otsubo H. Epileptogenic high-frequency oscillations skip the motor area in children with multilobar drug-resistant epilepsy. Clin Neurophysiol. 2017 07; 128(7):1197-1205. PMID: 28521267.
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    19. Kagawa K, Iida K, Baba S, Hashizume A, Katagiri M, Kurisu K, Otsubo H. Effective withdrawal of antiepileptic drugs in premonitoring admission to capture seizures during limited video-EEG monitoring. Epilepsia Open. 2017 06; 2(2):172-179. PMID: 29588946.
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    20. Otsubo H, Akatsuka Y, Takashima H, Suzuki T, Suzuki D, Kamiya T, Ikeda Y, Matsumura T, Yamashita T, Shino K. MRI depiction and 3D visualization of three anterior cruciate ligament bundles. Clin Anat. 2017 Mar; 30(2):276-283. PMID: 27888604.
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    21. Sakuma S, Halliday WC, Nomura R, Baba S, Sato Y, Okanari K, Nakajima M, Widjaja E, Boelman C, Ochi A, Snead OC, Rutka JT, Drake J, Miller S, Otsubo H. Increased subcortical oligodendroglia-like cells in pharmacoresistant focal epilepsy in children correlate with extensive epileptogenic zones. Epilepsia. 2016 12; 57(12):2031-2038. PMID: 27859041.
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    22. Okanishi T, Akiyama T, Mayo E, Honda Y, Ueda-Kawada C, Nakajima M, Homma Y, Ochi A, Go C, Widjaja E, Chuang SH, Rutka JT, Drake J, Snead OC, Otsubo H. Magnetoencephalography spike sources interrelate the extensive epileptogenic zone of tuberous sclerosis complex. Epilepsy Res. 2016 11; 127:302-310. PMID: 27693986.
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    23. Baba S, Onga K, Kakizawa S, Ohyama K, Yasuda K, Otsubo H, Scott BW, Burnham WM, Matsuo T, Nagata I, Mori N. Involvement of the neuronal phosphotyrosine signal adaptor N-Shc in kainic acid-induced epileptiform activity. Sci Rep. 2016 06 08; 6:27511. PMID: 27273072.
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    24. Nakajima M, Widjaja E, Baba S, Sato Y, Yoshida R, Tabei M, Okazaki A, Sakuma S, Holowka SA, Ochi A, Snead OC, Rutka JT, Drake JM, Shiraishi H, Doesburg S, Otsubo H. Remote MEG dipoles in focal cortical dysplasia at bottom of sulcus. Epilepsia. 2016 07; 57(7):1169-78. PMID: 27254541.
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    25. Nita DA, Moldovan M, Sharma R, Avramescu S, Otsubo H, Hahn CD. Burst-suppression is reactive to photic stimulation in comatose children with acquired brain injury. Clin Neurophysiol. 2016 08; 127(8):2921-30. PMID: 27266662.
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    26. Wong SM, Ibrahim GM, Ochi A, Otsubo H, Rutka JT, Snead OC, Doesburg SM. moviEEG: An animation toolbox for visualization of intracranial electroencephalography synchronization dynamics. Clin Neurophysiol. 2016 06; 127(6):2370-8. PMID: 27178855.
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    27. Kiehna EN, Widjaja E, Holowka S, Carter Snead O, Drake J, Weiss SK, Ochi A, Thompson EM, Go C, Otsubo H, Donner EJ, Rutka JT. Utility of diffusion tensor imaging studies linked to neuronavigation and other modalities in repeat hemispherotomy for intractable epilepsy. J Neurosurg Pediatr. 2016 Apr; 17(4):483-90. PMID: 26651159.
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    28. Okanari K, Baba S, Otsubo H, Widjaja E, Sakuma S, Go CY, Jones KC, Nishioka K, Oba S, Matsui T, Ueno M, Ukitsu S, Rutka JT, Drake JM, Donner EJ, Weiss SK, Snead OC, Ochi A. Rapid eye movement sleep reveals epileptogenic spikes for resective surgery in children with generalized interictal discharges. Epilepsia. 2015 Sep; 56(9):1445-53. PMID: 26174651.
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    29. Kagawa K, Iida K, Hashizume A, Katagiri M, Baba S, Kurisu K, Otsubo H. Magnetoencephalography using gradient magnetic field topography (GMFT) can predict successful anterior corpus callosotomy in patients with drop attacks. Clin Neurophysiol. 2016 Jan; 127(1):221-229. PMID: 26187350.
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    30. Limotai C, Go CY, Baba S, Okanari K, Ochi A, Rutka JT, Snead OC, Otsubo H. Steal phenomenon in Sturge-Weber syndrome imitating an ictal electroencephalography change in the contralateral hemisphere: report of 2 cases. J Neurosurg Pediatr. 2015 Aug; 16(2):212-6. PMID: 25955807.
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    31. Akiyama T, Akiyama M, Kobayashi K, Okanishi T, Boelman CG, Nita DA, Ochi A, Go CY, Snead OC, Rutka JT, Drake JM, Chuang S, Otsubo H. Spatial relationship between fast and slow components of ictal activities and interictal epileptiform discharges in epileptic spasms. Clin Neurophysiol. 2015 Sep; 126(9):1684-91. PMID: 25557960.
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    32. Sato Y, Doesburg SM, Wong SM, Okanishi T, Anderson R, Nita DA, Ochi A, Otsubo H. Dynamic changes of interictal post-spike slow waves toward seizure onset in focal cortical dysplasia type II. Clin Neurophysiol. 2015 Sep; 126(9):1670-6. PMID: 25499612.
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    33. Sato Y, Doesburg SM, Wong SM, Ochi A, Otsubo H. Dynamic preictal relations in FCD type II: potential for early seizure detection in focal epilepsy. Epilepsy Res. 2015 Feb; 110:26-31. PMID: 25616452.
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    34. Pang EW, Chu BH, Otsubo H. Occipital lobe lesions result in a displacement of magnetoencephalography visual evoked field dipoles. J Clin Neurophysiol. 2014 Oct; 31(5):456-61. PMID: 25271686.
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    35. Albert GW, Ibrahim GM, Otsubo H, Ochi A, Go CY, Snead OC, Drake JM, Rutka JT. Magnetoencephalography-guided resection of epileptogenic foci in children. J Neurosurg Pediatr. 2014 Nov; 14(5):532-7. PMID: 25238627.
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    36. Okanishi T, Akiyama T, Tanaka S, Mayo E, Mitsutake A, Boelman C, Go C, Snead OC, Drake J, Rutka J, Ochi A, Otsubo H. Interictal high frequency oscillations correlating with seizure outcome in patients with widespread epileptic networks in tuberous sclerosis complex. Epilepsia. 2014 Oct; 55(10):1602-10. PMID: 25196064.
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    37. Alshafai L, Ochi A, Go C, McCoy B, Hawkins C, Otsubo H, Snead OC, Rutka J, Widjaja E. Clinical, EEG, MRI, MEG, and surgical outcomes of pediatric epilepsy with astrocytic inclusions versus focal cortical dysplasia. Epilepsia. 2014 Oct; 55(10):1568-75. PMID: 25169867.
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    38. Hamasaki T, Otsubo H, Uchikawa H, Yamada K, Kuratsu J. Olfactory auras caused by a very focal isolated epileptic network in the amygdala. Epilepsy Behav Case Rep. 2014; 2:142-4. PMID: 25667893; PMCID: PMC4307874.
    39. Okanishi T, Yamamoto H, Hosokawa T, Ando N, Nagayama Y, Hashimoto Y, Maihara T, Goto T, Kubota T, Kawaguchi C, Yoshida H, Sugiura K, Itomi S, Ohno K, Takanashi J, Hayakawa M, Otsubo H, Okumura A. Diffusion-weighted MRI for early diagnosis of neonatal herpes simplex encephalitis. Brain Dev. 2015 Apr; 37(4):423-31. PMID: 25149136.
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    40. Sakuma S, Tokuhara D, Otsubo H, Yamano T, Shintaku H. Dynamic Change in Cells Expressing IL-1ß in Rat Hippocampus after Status Epilepticus. Jpn Clin Med. 2014; 5:25-32. PMID: 25210490; PMCID: PMC4134005.
    41. Ibrahim GM, Cassel D, Morgan BR, Smith ML, Otsubo H, Ochi A, Taylor M, Rutka JT, Snead OC, Doesburg S. Resilience of developing brain networks to interictal epileptiform discharges is associated with cognitive outcome. Brain. 2014 Oct; 137(Pt 10):2690-702. PMID: 25104094; PMCID: PMC4163036.
    42. Sato Y, Doesburg SM, Wong SM, Boelman C, Ochi A, Otsubo H. Preictal surrender of post-spike slow waves to spike-related high-frequency oscillations (80-200 Hz) is associated with seizure initiation. Epilepsia. 2014 Sep; 55(9):1399-405. PMID: 25070562.
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    43. Bennett-Back O, Ochi A, Widjaja E, Nambu S, Kamiya A, Go C, Chuang S, Rutka JT, Drake J, Snead OC, Otsubo H. Magnetoencephalography helps delineate the extent of the epileptogenic zone for surgical planning in children with intractable epilepsy due to porencephalic cyst/encephalomalacia. J Neurosurg Pediatr. 2014 Sep; 14(3):271-8. PMID: 25014323.
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    44. Okanisni T, Iida K, Ochi A, Otsubo H. [Epilepsy surgery in children with tuberous sclerosis complex]. No To Hattatsu. 2014 Jul; 46(4):257-63. PMID: 25154221.
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    45. Ito T, Otsubo H, Shiraishi H, Yagyu K, Takahashi Y, Ueda Y, Takeuchi F, Takahashi K, Nakane S, Kohsaka S, Saitoh S. Advantageous information provided by magnetoencephalography for patients with neocortical epilepsy. Brain Dev. 2015 Feb; 37(2):237-42. PMID: 24819913.
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    46. Mohammadi M, Okanishi T, Okanari K, Baba S, Sumiyoshi H, Sakuma S, Ochi A, Widjaja E, Go CY, Snead OC, Otsubo H. Asymmetrical generalized paroxysmal fast activities in children with intractable localization-related epilepsy. Brain Dev. 2015 Jan; 37(1):59-65. PMID: 24809226.
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    47. Sakuma S, Halliday WC, Nomura R, Ochi A, Otsubo H. Increased population of oligodendroglia-like cells in pediatric intractable epilepsy. Neurosci Lett. 2014 Apr 30; 566:188-93. PMID: 24631559.
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    48. Ibrahim GM, Wong SM, Anderson RA, Singh-Cadieux G, Akiyama T, Ochi A, Otsubo H, Okanishi T, Valiante TA, Donner E, Rutka JT, Snead OC, Doesburg SM. Dynamic modulation of epileptic high frequency oscillations by the phase of slower cortical rhythms. Exp Neurol. 2014 Jan; 251:30-8. PMID: 24211781.
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    49. Ibrahim GM, Anderson R, Akiyama T, Ochi A, Otsubo H, Singh-Cadieux G, Donner E, Rutka JT, Snead OC, Doesburg SM. Neocortical pathological high-frequency oscillations are associated with frequency-dependent alterations in functional network topology. J Neurophysiol. 2013 Nov; 110(10):2475-83. PMID: 24004529.
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    50. Lim ME, Bowen JM, Snead OC, Elliott I, Donner E, Weiss SK, Otsubo H, Ochi A, Drake J, Rutka JT, Worster A, Hopkins RB, Goeree R, Tarride JE. Access to surgery for paediatric patients with medically refractory epilepsy: a systems analysis. Epilepsy Res. 2013 Dec; 107(3):286-96. PMID: 24192043.
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    51. Otsubo H, Nakazato N. [Preface: benefit of early surgcial intervention for children with epilepsy]. No To Hattatsu. 2013 May; 45(3):193-4. PMID: 23785832.
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    52. Hanaya R, Okamoto H, Fujimoto A, Ochi A, Go C, Snead CO, Widjaja E, Chuang SH, Kemp SM, Otsubo H. Total intravenous anesthesia affecting spike sources of magnetoencephalography in pediatric epilepsy patients: focal seizures vs. non-focal seizures. Epilepsy Res. 2013 Aug; 105(3):326-36. PMID: 23562603.
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    53. Mohamed IS, Otsubo H, Ferrari P, Sharma R, Ochi A, Elliott I, Go C, Chuang S, Rutka J, Snead C, Cheyne D. Source localization of interictal spike-locked neuromagnetic oscillations in pediatric neocortical epilepsy. Clin Neurophysiol. 2013 Aug; 124(8):1517-27. PMID: 23523111.
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    54. Widjaja E, Shammas A, Vali R, Otsubo H, Ochi A, Snead OC, Go C, Charron M. FDG-PET and magnetoencephalography in presurgical workup of children with localization-related nonlesional epilepsy. Epilepsia. 2013 Apr; 54(4):691-9. PMID: 23398491.
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    55. Shiraishi H, Haginoya K, Nakagawa E, Saitoh S, Kaneko Y, Nakasato N, Chan D, Otsubo H. Magnetoencephalography localizing spike sources of atypical benign partial epilepsy. Brain Dev. 2014 Jan; 36(1):21-7. PMID: 23384398.
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    56. Vachhrajani S, de Ribaupierre S, Otsubo H, Ochi A, Weiss SK, Donner EJ, Widjaja E, Kerr E, Smith ML, Drake J, Snead C, Rutka JT. Neurosurgical management of frontal lobe epilepsy in children. J Neurosurg Pediatr. 2012 Sep; 10(3):206-16. PMID: 22838737.
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    57. Ibrahim GM, Akiyama T, Ochi A, Otsubo H, Smith ML, Taylor MJ, Donner E, Rutka JT, Snead OC, Doesburg SM. Disruption of rolandic gamma-band functional connectivity by seizures is associated with motor impairments in children with epilepsy. PLoS One. 2012; 7(6):e39326. PMID: 22737233; PMCID: PMC3380842.
    58. Jacobs J, Staba R, Asano E, Otsubo H, Wu JY, Zijlmans M, Mohamed I, Kahane P, Dubeau F, Navarro V, Gotman J. High-frequency oscillations (HFOs) in clinical epilepsy. Prog Neurobiol. 2012 Sep; 98(3):302-15. PMID: 22480752; PMCID: PMC3674884.
    59. Ibrahim GM, Fallah A, Albert GW, Withers T, Otsubo H, Ochi A, Akiyama T, Donner EJ, Weiss S, Snead OC, Drake JM, Rutka JT. Occipital lobe epilepsy in children: characterization, evaluation and surgical outcomes. Epilepsy Res. 2012 May; 99(3):335-45. PMID: 22260921.
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    60. Visanji NP, Wong JC, Wang SX, Cappel B, Kleinschmidt-Demasters BK, Handler MH, Ochi A, Otsubo H, Rutka JT, Go C, Weiss S, Vinters HV, Hawkins CE, Desouza LV, Siu KW, Hazrati LN. A proteomic analysis of pediatric seizure cases associated with astrocytic inclusions. Epilepsia. 2012 Mar; 53(3):e50-4. PMID: 22220588.
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    61. Torres CV, Fallah A, Ibrahim GM, Cheshier S, Otsubo H, Ochi A, Chuang S, Snead OC, Holowka S, Rutka JT. The role of magnetoencephalography in children undergoing hemispherectomy. J Neurosurg Pediatr. 2011 Dec; 8(6):575-83. PMID: 22132915.
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    62. McCoy B, Sharma R, Ochi A, Go C, Otsubo H, Hutchison JS, Atenafu EG, Hahn CD. Predictors of nonconvulsive seizures among critically ill children. Epilepsia. 2011 Nov; 52(11):1973-8. PMID: 22003955.
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    63. Widjaja E, Geibprasert S, Otsubo H, Snead OC, Mahmoodabadi SZ. Diffusion tensor imaging assessment of the epileptogenic zone in children with localization-related epilepsy. AJNR Am J Neuroradiol. 2011 Nov-Dec; 32(10):1789-94. PMID: 21998108.
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    64. Nagarajan L, Ghosh S, Palumbo L, Akiyama T, Otsubo H. Fast activity during EEG seizures in neonates. Epilepsy Res. 2011 Nov; 97(1-2):162-9. PMID: 21889314.
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    65. Ochi A, Hung R, Weiss S, Widjaja E, To T, Nawa Y, Shima T, Go C, Akiyama T, Donner E, Drake J, Rutka JT, Snead OC, Otsubo H. Lateralized interictal epileptiform discharges during rapid eye movement sleep correlate with epileptogenic hemisphere in children with intractable epilepsy secondary to tuberous sclerosis complex. Epilepsia. 2011 Nov; 52(11):1986-94. PMID: 21801167.
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    66. Akiyama T, McCoy B, Go CY, Ochi A, Elliott IM, Akiyama M, Donner EJ, Weiss SK, Snead OC, Rutka JT, Drake JM, Otsubo H. Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy. Epilepsia. 2011 Oct; 52(10):1802-11. PMID: 21801168.
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    67. Akiyama T, Osada M, Isowa M, Go CY, Ochi A, Elliott IM, Akiyama M, Snead OC, Rutka JT, Drake JM, Otsubo H. High kurtosis of intracranial electroencephalogram as a marker of ictogenicity in pediatric epilepsy surgery. Clin Neurophysiol. 2012 Jan; 123(1):93-9. PMID: 21733751.
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    68. Mohamed IS, Otsubo H, Ferrari P, Ochi A, Snead OC, Cheyne D. Neuromagnetic cerebellar activation during seizures arising from the motor cortex. Epilepsy Res. 2011 Oct; 96(3):283-7. PMID: 21723094.
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    69. Viravan S, Go C, Ochi A, Akiyama T, Carter Snead O, Otsubo H. Jeavons syndrome existing as occipital cortex initiating generalized epilepsy. Epilepsia. 2011 Jul; 52(7):1273-9. PMID: 21729035.
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    70. Inage Y, Halliday WC, Go C, Ochi A, Akiyama T, Akiyama M, Widjaja E, Otsubo H. Histopathology of cortex and white matter in pediatric epileptic spasms: comparison with those of partial seizures. Brain Dev. 2012 Feb; 34(2):118-23. PMID: 21493023.
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    71. Akiyama T, Donner EJ, Go CY, Ochi A, Snead OC, Rutka JT, Otsubo H. Focal-onset myoclonic seizures and secondary bilateral synchrony. Epilepsy Res. 2011 Jun; 95(1-2):168-72. PMID: 21377332.
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    72. Kwan A, Ng WH, Otsubo H, Ochi A, Snead OC, Tamber MS, Rutka JT. Hemispherectomy for the control of intractable epilepsy in childhood: comparison of 2 surgical techniques in a single institution. Neurosurgery. 2010 Dec; 67(2 Suppl Operative):429-36. PMID: 21099569.
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    73. Akiyama T, Chan DW, Go CY, Ochi A, Elliott IM, Donner EJ, Weiss SK, Snead OC, Rutka JT, Drake JM, Otsubo H. Topographic movie of intracranial ictal high-frequency oscillations with seizure semiology: epileptic network in Jacksonian seizures. Epilepsia. 2011 Jan; 52(1):75-83. PMID: 21070217.
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    74. Stewart CP, Otsubo H, Ochi A, Sharma R, Hutchison JS, Hahn CD. Seizure identification in the ICU using quantitative EEG displays. Neurology. 2010 Oct 26; 75(17):1501-8. PMID: 20861452; PMCID: PMC2974462.
    75. Shirozu H, Iida K, Hashizume A, Hanaya R, Kiura Y, Kurisu K, Arita K, Otsubo H. Gradient magnetic-field topography reflecting cortical activities of neocortical epilepsy spikes. Epilepsy Res. 2010 Jun; 90(1-2):121-31. PMID: 20451350.
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    76. Akiyama T, Otsubo H. [Antiepileptic drugs in North America]. Brain Nerve. 2010 May; 62(5):519-26. PMID: 20450099.
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    77. Widjaja E, Simao G, Mahmoodabadi SZ, Ochi A, Snead OC, Rutka J, Otsubo H. Diffusion tensor imaging identifies changes in normal-appearing white matter within the epileptogenic zone in tuberous sclerosis complex. Epilepsy Res. 2010 May; 89(2-3):246-53. PMID: 20129760.
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    78. Ng WH, Ochi A, Rutka JT, Strantzas S, Holmes L, Otsubo H. Stimulation threshold potentials of intraoperative cortical motor mapping using monopolar trains of five in pediatric epilepsy surgery. Childs Nerv Syst. 2010 May; 26(5):675-9. PMID: 19949801.
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    79. Sugiyama I, Imai K, Yamaguchi Y, Ochi A, Akizuki Y, Go C, Akiyama T, Snead OC, Rutka JT, Drake JM, Widjaja E, Chuang SH, Cheyne D, Otsubo H. Localization of epileptic foci in children with intractable epilepsy secondary to multiple cortical tubers by using synthetic aperture magnetometry kurtosis. J Neurosurg Pediatr. 2009 Dec; 4(6):515-22. PMID: 19951036.
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    80. Bhardwaj RD, Mahmoodabadi SZ, Otsubo H, Snead OC, Rutka JT, Widjaja E. Diffusion tensor tractography detection of functional pathway for the spread of epileptiform activity between temporal lobe and Rolandic region. Childs Nerv Syst. 2010 Feb; 26(2):185-90. PMID: 19915854.
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    86. Nakayama T, Otsuki T, Kaneko Y, Nakama H, Kaido T, Otsubo H, Nakagawa E, Sasaki M, Sugai K. Repeat magnetoencephalography and surgeries to eliminate atonic seizures of non-lesional frontal lobe epilepsy. Epilepsy Res. 2009 Apr; 84(2-3):263-7. PMID: 19297132.
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    88. Widjaja E, Zarei Mahmoodabadi S, Otsubo H, Snead OC, Holowka S, Bells S, Raybaud C. Subcortical alterations in tissue microstructure adjacent to focal cortical dysplasia: detection at diffusion-tensor MR imaging by using magnetoencephalographic dipole cluster localization. Radiology. 2009 Apr; 251(1):206-15. PMID: 19190250.
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    92. Galicia E, Imai K, Mohamed IS, Go C, Fujimoto A, Ochi A, Sakuta R, Halliday W, Rutka JT, Chuang SH, Snead OC, Otsubo H. Changing ictal-onset EEG patterns in children with cortical dysplasia. Brain Dev. 2009 Sep; 31(8):569-76. PMID: 18834684.
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    98. Hazrati LN, Kleinschmidt-DeMasters BK, Handler MH, Smith ML, Ochi A, Otsubo H, Rutka JT, Go C, Weiss S, Hawkins CE. Astrocytic inclusions in epilepsy: expanding the spectrum of filaminopathies. J Neuropathol Exp Neurol. 2008 Jul; 67(7):669-76. PMID: 18596546.
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    101. Pang EW, Drake JM, Otsubo H, Martineau A, Strantzas S, Cheyne D, Gaetz W. Intraoperative confirmation of hand motor area identified preoperatively by magnetoencephalography. Pediatr Neurosurg. 2008; 44(4):313-7. PMID: 18504418.
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    103. Otsubo H, Ochi A, Imai K, Akiyama T, Fujimoto A, Go C, Dirks P, Donner EJ. High-frequency oscillations of ictal muscle activity and epileptogenic discharges on intracranial EEG in a temporal lobe epilepsy patient. Clin Neurophysiol. 2008 Apr; 119(4):862-8. PMID: 18289931.
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    106. Ramachandrannair R, Ochi A, Imai K, Benifla M, Akiyama T, Holowka S, Rutka JT, Snead OC, Otsubo H. Epileptic spasms in older pediatric patients: MEG and ictal high-frequency oscillations suggest focal-onset seizures in a subset of epileptic spasms. Epilepsy Res. 2008 Feb; 78(2-3):216-24. PMID: 18215506.
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    107. Otsubo H, Imai K. Clinical neurophysiology of cortical malformations: magnetoencephalography and electroencephalography. Handb Clin Neurol. 2008; 87:503-16. PMID: 18809041.
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    108. Imai K, Otsubo H, Sell E, Mohamed I, Ochi A, RamachandranNair R, Snead OC. MEG source estimation from mesio-basal temporal areas in a child with a porencephalic cyst. Acta Neurol Scand. 2007 Oct; 116(4):263-7. PMID: 17824907.
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    109. Mohamed IS, Otsubo H, Ochi A, Elliott I, Donner E, Chuang S, Sharma R, Holowka S, Rutka J, Snead OC. Utility of magnetoencephalography in the evaluation of recurrent seizures after epilepsy surgery. Epilepsia. 2007 Nov; 48(11):2150-9. PMID: 17727666.
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    110. RamachandranNair R, Ochi A, Benifla M, Rutka JT, Snead OC, Otsubo H. Benign epileptiform discharges in Rolandic region with mesial temporal lobe epilepsy: MEG, scalp and intracranial EEG features. Acta Neurol Scand. 2007 Jul; 116(1):59-64. PMID: 17587257.
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    111. Kadis DS, Iida K, Kerr EN, Logan WJ, McAndrews MP, Ochi A, Otsubo H, Rutka JT, Snead OC, Weiss SK, Smith ML. Intrahemispheric reorganization of language in children with medically intractable epilepsy of the left hemisphere. J Int Neuropsychol Soc. 2007 May; 13(3):505-16. PMID: 17445300.
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    112. Mohamed IS, Otsubo H, Imai K, Shroff M, Sharma R, Chuang SH, Donner E, Drake J, Snead OC. Surgical treatment for acute symptomatic refractory status epilepticus: a case report. J Child Neurol. 2007 Apr; 22(4):435-9. PMID: 17621524.
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    114. Hashizume A, Iida K, Shirozu H, Hanaya R, Kiura Y, Kurisu K, Otsubo H. Gradient magnetic-field topography for dynamic changes of epileptic discharges. Brain Res. 2007 May 04; 1144:175-9. PMID: 17331481.
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    117. Mohamed IS, Otsubo H, Donner E, Ochi A, Sharma R, Drake J, Rutka JT, Chuang SH, Holowka S, Snead OC. Magnetoencephalography for surgical treatment of refractory status epilepticus. Acta Neurol Scand Suppl. 2007; 186:29-36. PMID: 17784535.
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    118. Benifla M, Otsubo H, Ochi A, Weiss SK, Donner EJ, Shroff M, Chuang S, Hawkins C, Drake JM, Elliott I, Smith ML, Snead OC, Rutka JT. Temporal lobe surgery for intractable epilepsy in children: an analysis of outcomes in 126 children. Neurosurgery. 2006 Dec; 59(6):1203-13; discussion 1213-4. PMID: 17277683.
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    120. Akiyama T, Otsubo H, Ochi A, Galicia EZ, Weiss SK, Donner EJ, Rutka JT, Snead OC. Topographic movie of ictal high-frequency oscillations on the brain surface using subdural EEG in neocortical epilepsy. Epilepsia. 2006 Nov; 47(11):1953-7. PMID: 17116039.
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    121. Saengpattrachai M, Sharma R, Hunjan A, Shroff M, Ochi A, Otsubo H, Cortez MA, Carter Snead O. Nonconvulsive seizures in the pediatric intensive care unit: etiology, EEG, and brain imaging findings. Epilepsia. 2006 Sep; 47(9):1510-8. PMID: 16981868.
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    122. Mohamed IS, Otsubo H, Pang E, Chuang SH, Rutka JT, Dirks P, Weiss SK, Snead OC. Magnetoencephalographic spike sources associated with auditory auras in paediatric localisation-related epilepsy. J Neurol Neurosurg Psychiatry. 2006 Nov; 77(11):1256-61. PMID: 16891385; PMCID: PMC2077384.
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    124. Oishi M, Otsubo H, Iida K, Suyama Y, Ochi A, Weiss SK, Xiang J, Gaetz W, Cheyne D, Chuang SH, Rutka JT, Snead OC. Preoperative simulation of intracerebral epileptiform discharges: synthetic aperture magnetometry virtual sensor analysis of interictal magnetoencephalography data. J Neurosurg. 2006 Jul; 105(1 Suppl):41-9. PMID: 16871869.
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    126. Benifla M, Otsubo H, Ochi A, Snead OC, Rutka JT. Multiple subpial transections in pediatric epilepsy: indications and outcomes. Childs Nerv Syst. 2006 Aug; 22(8):992-8. PMID: 16786370.
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    129. Oishi M, Kameyama S, Masuda H, Tohyama J, Kanazawa O, Sasagawa M, Otsubo H. Single and multiple clusters of magnetoencephalographic dipoles in neocortical epilepsy: significance in characterizing the epileptogenic zone. Epilepsia. 2006 Feb; 47(2):355-64. PMID: 16499760.
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    132. RamachandranNair R, Ochi A, Akiyama T, Buckley DJ, Soman TB, Weiss SK, Otsubo H. Partial seizures triggering infantile spasms in the presence of a basal ganglia glioma. Epileptic Disord. 2005 Dec; 7(4):378-82. PMID: 16338683.
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    133. RamachandranNair R, Sharma R, Weiss SK, Otsubo H, Cortez MA. A reappraisal of rhythmic coma patterns in children. Can J Neurol Sci. 2005 Nov; 32(4):518-23. PMID: 16408585.
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    136. Xiao Z, Xiang J, Holowka S, Hunjan A, Sharma R, Otsubo H, Chuang S. Volumetric localization of epileptic activities in tuberous sclerosis using synthetic aperture magnetometry. Pediatr Radiol. 2006 Jan; 36(1):16-21. PMID: 16240141.
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    137. Iida K, Otsubo H, Mohamed IS, Okuda C, Ochi A, Weiss SK, Chuang SH, Snead OC. Characterizing magnetoencephalographic spike sources in children with tuberous sclerosis complex. Epilepsia. 2005 Sep; 46(9):1510-7. PMID: 16146447.
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    138. Otsubo H, Kaito K, Asai O, Usui N, Kobayashi M, Hoshi Y. Persistent nucleated red blood cells in peripheral blood is a poor prognostic factor in patients undergoing stem cell transplantation. Clin Lab Haematol. 2005 Aug; 27(4):242-6. PMID: 16048491.
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    139. Arita K, Kurisu K, Kiura Y, Iida K, Otsubo H. Hypothalamic hamartoma. Neurol Med Chir (Tokyo). 2005 May; 45(5):221-31. PMID: 15914961.
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    140. Otsubo H, Iida K, Oishi M, Okuda C, Ochi A, Pang E, Weiss SK, Rutka JT, Chuang SH, Snead OC. Neurophysiologic findings of neuronal migration disorders: intrinsic epileptogenicity of focal cortical dysplasia on electroencephalography, electrocorticography, and magnetoencephalography. J Child Neurol. 2005 Apr; 20(4):357-63. PMID: 15921239.
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    141. Sakuta R, Otsubo H, Nolan MA, Weiss SK, Hawkins C, Rutka JT, Chuang NA, Chuang SH, Snead OC. Recurrent intractable seizures in children with cortical dysplasia adjacent to dysembryoplastic neuroepithelial tumor. J Child Neurol. 2005 Apr; 20(4):377-84. PMID: 15921242.
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    142. Nolan MA, Otsubo H, Iida K, Minassian BA. Startle-induced seizures associated with infantile hemiplegia: implication of the supplementary motor area. Epileptic Disord. 2005 Mar; 7(1):49-52. PMID: 15741141.
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    143. Iida K, Otsubo H, Matsumoto Y, Ochi A, Oishi M, Holowka S, Pang E, Elliott I, Weiss SK, Chuang SH, Snead OC, Rutka JT. Characterizing magnetic spike sources by using magnetoencephalography-guided neuronavigation in epilepsy surgery in pediatric patients. J Neurosurg. 2005 Mar; 102(2 Suppl):187-96. PMID: 16156229.
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    144. Al-Futaisi A, Banwell B, Ochi A, Hew J, Chu B, Oishi M, Otsubo H. Hidden focal EEG seizures during prolonged suppressions and high-amplitude bursts in early infantile epileptic encephalopathy. Clin Neurophysiol. 2005 May; 116(5):1113-7. PMID: 15826852.
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    145. Iida K, Otsubo H, Arita K, Andermann F, Olivier A. Cortical resection with electrocorticography for intractable porencephaly-related partial epilepsy. Epilepsia. 2005 Jan; 46(1):76-83. PMID: 15660771.
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    147. Nolan MA, Sakuta R, Chuang N, Otsubo H, Rutka JT, Snead OC, Hawkins CE, Weiss SK. Dysembryoplastic neuroepithelial tumors in childhood: long-term outcome and prognostic features. Neurology. 2004 Jun 22; 62(12):2270-6. PMID: 15210893.
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    148. Hader WJ, Mackay M, Otsubo H, Chitoku S, Weiss S, Becker L, Snead OC, Rutka JT. Cortical dysplastic lesions in children with intractable epilepsy: role of complete resection. J Neurosurg. 2004 Feb; 100(2 Suppl Pediatrics):110-7. PMID: 14758938.
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    149. Blount JP, Langburt W, Otsubo H, Chitoku S, Ochi A, Weiss S, Snead OC, Rutka JT. Multiple subpial transections in the treatment of pediatric epilepsy. J Neurosurg. 2004 Feb; 100(2 Suppl Pediatrics):118-24. PMID: 14758939.
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    150. Pang EW, Gaetz W, Otsubo H, Chuang S, Cheyne D. Localization of auditory N1 in children using MEG: source modeling issues. Int J Psychophysiol. 2003 Dec; 51(1):27-35. PMID: 14629920.
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    151. Clarke DF, Otsubo H, Weiss SK, Chitoku S, Chuang SH, Logan WJ, Smith ML, Elliot I, Pang EW, Rutka JT, Snead OC. The significance of ear plugging in localization-related epilepsy. Epilepsia. 2003 Dec; 44(12):1562-7. PMID: 14636328.
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    152. Kitayama M, Otsubo H, Parvez S, Lodha A, Ying E, Parvez B, Ishii R, Mizuno-Matsumoto Y, Zoroofi RA, Snead OC. Wavelet analysis for neonatal electroencephalographic seizures. Pediatr Neurol. 2003 Oct; 29(4):326-33. PMID: 14643396.
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    153. Onal C, Otsubo H, Araki T, Chitoku S, Ochi A, Weiss S, Elliott I, Snead OC, Rutka JT, Logan W. Complications of invasive subdural grid monitoring in children with epilepsy. J Neurosurg. 2003 May; 98(5):1017-26. PMID: 12744361.
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    154. Chitoku S, Otsubo H, Harada Y, Jay V, Rutka JT, Weiss SK, Elliott I, Ochi A, Kitayama M, Snead OC. Characteristics of prolonged afterdischarges in children with malformations of cortical development. J Child Neurol. 2003 Apr; 18(4):247-53. PMID: 12760426.
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    155. Oishi M, Otsubo H, Kameyama S, Wachi M, Tanaka K, Masuda H, Tanaka R. Ictal magnetoencephalographic discharges from elementary visual hallucinations of status epilepticus. J Neurol Neurosurg Psychiatry. 2003 Apr; 74(4):525-7. PMID: 12640082; PMCID: PMC1738400.
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    157. Askalan R, Mackay M, Brian J, Otsubo H, McDermott C, Bryson S, Boyd J, Snead C, Roberts W, Weiss S. Prospective preliminary analysis of the development of autism and epilepsy in children with infantile spasms. J Child Neurol. 2003 Mar; 18(3):165-70. PMID: 12731640.
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    158. Mackay MT, Becker LE, Chuang SH, Otsubo H, Chuang NA, Rutka J, Ben-Zeev B, Snead OC, Weiss SK. Malformations of cortical development with balloon cells: clinical and radiologic correlates. Neurology. 2003 Feb 25; 60(4):580-7. PMID: 12601096.
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    159. Chitoku S, Otsubo H, Ichimura T, Saigusa T, Ochi A, Shirasawa A, Kamijo K, Yamazaki T, Pang E, Rutka JT, Weiss SK, Snead OC. Characteristics of dipoles in clustered individual spikes and averaged spikes. Brain Dev. 2003 Jan; 25(1):14-21. PMID: 12536028.
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    160. Oishi M, Otsubo H, Kameyama S, Morota N, Masuda H, Kitayama M, Tanaka R. Epileptic spikes: magnetoencephalography versus simultaneous electrocorticography. Epilepsia. 2002 Nov; 43(11):1390-5. PMID: 12423390.
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    161. Chen LS, Otsubo H, Ochi A, Lai WW, Sutoyo D, Snead OC. Continuous potential display of ictal electrocorticography. J Clin Neurophysiol. 2002 Jun; 19(3):192-203. PMID: 12226564.
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    162. Akai T, Otsubo H, Pang EW, Rutka JT, Chitoku S, Weiss SK, Snead OC. Complex central cortex in pediatric patients with malformations of cortical development. J Child Neurol. 2002 May; 17(5):347-52. PMID: 12150581.
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    163. Ochi A, Otsubo H, Honda Y, Hara Y, Sharma R, Elliott I, Rutka JT, Chuang SH, Kamijo K, Kiyuna T, Yamazaki T, Snead OC. Electroencephalographic dipoles of spikes with and without myoclonic jerks caused by epilepsia partialis continua. J Child Neurol. 2002 Feb; 17(2):127-31. PMID: 11952073.
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    164. Chuang NA, Otsubo H, Chuang SH. Magnetic resonance imaging in pediatric epilepsy. Top Magn Reson Imaging. 2002 Feb; 13(1):39-60. PMID: 11847500.
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    165. Xiang J, Chuang S, Wilson D, Otsubo H, Pang E, Holowka S, Sharma R, Ochi A, Chitoku S. Sound motion evoked magnetic fields. Clin Neurophysiol. 2002 Jan; 113(1):1-9. PMID: 11801418.
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    166. Kolski H, Otsubo H. The Landau-Kleffner syndrome. Adv Exp Med Biol. 2002; 497:195-208. PMID: 11993733.
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    167. Xiang J, Wilson D, Otsubo H, Ishii R, Chuang S. Neuromagnetic spectral distribution of implicit processing of words. Neuroreport. 2001 Dec 21; 12(18):3923-7. PMID: 11742212.
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    169. Woo CL, Chuang SH, Becker LE, Jay V, Otsubo H, Rutka JT, Snead OC. Radiologic-pathologic correlation in focal cortical dysplasia and hemimegalencephaly in 18 children. Pediatr Neurol. 2001 Oct; 25(4):295-303. PMID: 11704398.
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    170. Ochi A, Otsubo H, Sharma R, Hunjan A, Rutka JT, Chuang SH, Kamijo K, Yamazaki T, Quint P, Kurelowech L, Sobel DF, Aung MH, Snead OC. Comparison of electroencephalographic dipoles of interictal spikes from prolonged scalp video-electroencephalography and magnetoencephalographic dipoles from short-term recording in children with extratemporal lobe epilepsy. J Child Neurol. 2001 Sep; 16(9):661-7. PMID: 11575607.
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    171. Otsubo H, Chitoku S, Ochi A, Jay V, Rutka JT, Smith ML, Elliott IM, Snead OC. Malignant rolandic-sylvian epilepsy in children: diagnosis, treatment, and outcomes. Neurology. 2001 Aug 28; 57(4):590-6. PMID: 11524465.
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    172. Hodaie M, Musharbash A, Otsubo H, Snead OC, Chitoku S, Ochi A, Holowka S, Hoffman HJ, Rutka JT. Image-guided, frameless stereotactic sectioning of the corpus callosum in children with intractable epilepsy. Pediatr Neurosurg. 2001 Jun; 34(6):286-94. PMID: 11455228.
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    173. Otsubo H, Shirasawa A, Chitoku S, Rutka JT, Wilson SB, Snead OC. Computerized brain-surface voltage topographic mapping for localization of intracranial spikes from electrocorticography. Technical note. J Neurosurg. 2001 Jun; 94(6):1005-9. PMID: 11409502.
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    174. Chitoku S, Otsubo H, Harada Y, Jay V, Rutka JT, Weiss SK, Abdoll M, Snead OC. Extraoperative cortical stimulation of motor function in children. Pediatr Neurol. 2001 May; 24(5):344-50. PMID: 11516607.
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    175. Ochi A, Otsubo H, Chitoku S, Hunjan A, Sharma R, Rutka JT, Chuang SH, Kamijo K, Yamazaki T, Snead OC. Dipole localization for identification of neuronal generators in independent neighboring interictal EEG spike foci. Epilepsia. 2001 Apr; 42(4):483-90. PMID: 11440343.
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    176. Otsubo H, Snead OC. Magnetoencephalography and magnetic source imaging in children. J Child Neurol. 2001 Apr; 16(4):227-35. PMID: 11332456.
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    177. Cheng WW, Otsubo H, Snead OC. Surgery for intractable epilepsy in a 14-year-old girl. Hong Kong Med J. 2001 Mar; 7(1):97-100. PMID: 11406683.
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    178. Ohtsuka Y, Otsubo H. [Surgical treatment of refractory childhood epilepsy with special reference to the role of pediatric neurologists: introductory remarks]. No To Hattatsu. 2001 Mar; 33(2):121-3. PMID: 11260913.
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    179. Otsubo H. [Pre- and intra-operative evaluation of epileptic children with intractable seizure disorders: the hospital for sick children]. No To Hattatsu. 2001 Mar; 33(2):128-34. PMID: 11260915.
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    180. Klinger G, Chin CN, Otsubo H, Beyene J, Perlman M. Prognostic value of EEG in neonatal bacterial meningitis. Pediatr Neurol. 2001 Jan; 24(1):28-31. PMID: 11182277.
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    181. Gajjar M, Geva E, Humphries T, Peterson-Badali M, Otsubo H. A New Scale to Assess Culture-Specific Beliefs and Attitudes about Epilepsy. Epilepsy Behav. 2000 Aug; 1(4):235-255. PMID: 12609440.
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    182. Sobel DF, Aung M, Otsubo H, Smith MC. Magnetoencephalography in children with Landau-Kleffner syndrome and acquired epileptic aphasia. AJNR Am J Neuroradiol. 2000 Feb; 21(2):301-7. PMID: 10696012.
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    183. Ochi A, Otsubo H, Shirasawa A, Hunjan A, Sharma R, Bettings M, Rutka JT, Kamijo K, Yamazaki T, Wilson SB, Snead OC. Systematic approach to dipole localization of interictal EEG spikes in children with extratemporal lobe epilepsies. Clin Neurophysiol. 2000 Jan; 111(1):161-8. PMID: 10656524.
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    184. Rutka JT, Otsubo H, Kitano S, Sakamoto H, Shirasawa A, Ochi A, Snead OC. Utility of digital camera-derived intraoperative images in the planning of epilepsy surgery for children. Neurosurgery. 1999 Nov; 45(5):1186-91. PMID: 10549936.
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    185. Minassian BA, Otsubo H, Weiss S, Elliott I, Rutka JT, Snead OC. Magnetoencephalographic localization in pediatric epilepsy surgery: comparison with invasive intracranial electroencephalography. Ann Neurol. 1999 Oct; 46(4):627-33. PMID: 10514100.
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    186. Sugimoto T, Otsubo H, Hwang PA, Hoffman HJ, Jay V, Snead OC. Outcome of epilepsy surgery in the first three years of life. Epilepsia. 1999 May; 40(5):560-5. PMID: 10386524.
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    187. Otsubo H, Sharma R, Elliott I, Holowka S, Rutka JT, Snead OC. Confirmation of two magnetoencephalographic epileptic foci by invasive monitoring from subdural electrodes in an adolescent with right frontocentral epilepsy. Epilepsia. 1999 May; 40(5):608-13. PMID: 10386530.
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    188. Otsubo H, Steinlin M, Shirasawa A, Hwang PA, Munn R, Jay V, Hoffman HJ. Interhemispheric interactions analyzed by coherence during flexor spasms. Clin Neurophysiol. 1999 Feb; 110(2):374-7. PMID: 10210627.
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    189. Guerreiro MM, Andermann F, Andermann E, Palmini A, Hwang P, Hoffman HJ, Otsubo H, Bastos A, Dubeau F, Snipes GJ, Olivier A, Rasmussen T. Surgical treatment of epilepsy in tuberous sclerosis: strategies and results in 18 patients. Neurology. 1998 Nov; 51(5):1263-9. PMID: 9818843.
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    190. Yamanouchi H, Jay V, Otsubo H, Kaga M, Becker LE, Takashima S. Early forms of microtubule-associated protein are strongly expressed in cortical dysplasia. Acta Neuropathol. 1998 May; 95(5):466-70. PMID: 9600592.
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    191. Kolski H, Ford-Jones EL, Richardson S, Petric M, Nelson S, Jamieson F, Blaser S, Gold R, Otsubo H, Heurter H, MacGregor D. Etiology of acute childhood encephalitis at The Hospital for Sick Children, Toronto, 1994-1995. Clin Infect Dis. 1998 Feb; 26(2):398-409. PMID: 9502462.
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    192. Kaito K, Kobayashi M, Katayama T, Otsubo H, Ogasawara Y, Sekita T, Saeki A, Sakamoto M, Nishiwaki K, Masuoka H, Shimada T, Yoshida M, Hosoya T. Prognostic factors of hemophagocytic syndrome in adults: analysis of 34 cases. Eur J Haematol. 1997 Oct; 59(4):247-53. PMID: 9338623.
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    193. Stapleton SR, Kiriakopoulos E, Mikulis D, Drake JM, Hoffman HJ, Humphreys R, Hwang P, Otsubo H, Holowka S, Logan W, Rutka JT. Combined utility of functional MRI, cortical mapping, and frameless stereotaxy in the resection of lesions in eloquent areas of brain in children. Pediatr Neurosurg. 1997 Feb; 26(2):68-82. PMID: 9419036.
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    194. Otsubo H, Steinlin M, Hwang PA, Sharma R, Jay V, Becker LE, Hoffman HJ, Blaser S. Positive epileptiform discharges in children with neuronal migration disorders. Pediatr Neurol. 1997 Jan; 16(1):23-31. PMID: 9044397.
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    195. Jay V, Otsubo H, Hwang P, Hoffman HJ, Blaser S, Zielenska M. Coexistence of hemimegalencephaly and chronic encephalitis. Detection of cytomegalovirus by the polymerase chain reaction. Childs Nerv Syst. 1997 Jan; 13(1):35-41. PMID: 9083700.
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    196. Hwang PA, Otsubo H, Koo BK, Gilday DL, Chuang SH, Jay V, Hoffman HJ. Infantile spasms: cerebral blood flow abnormalities correlate with EEG, neuroimaging, and pathologic findings. Pediatr Neurol. 1996 Apr; 14(3):220-5. PMID: 8736406.
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    197. Otsubo H, Hwang PA, Gilday DL, Hoffman HJ. Location of epileptic foci on interictal and immediate postictal single photon emission tomography in children with localization-related epilepsy. J Child Neurol. 1995 Sep; 10(5):375-81. PMID: 7499757.
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    198. Otsubo H, Hwang PA, Hunjan A, Armstrong D, Holowka S, Drake JM, Hoffman HJ. Use of frameless stereotaxy with location of electroencephalographic electrodes on three-dimensional computed tomographic images in epilepsy surgery. J Clin Neurophysiol. 1995 Jul; 12(4):363-71. PMID: 7560023.
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    199. Chuang SH, Otsubo H, Hwang P, Orrison WW, Lewine JD. Pediatric magnetic source imaging. Neuroimaging Clin N Am. 1995 May; 5(2):289-303. PMID: 7640889.
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    200. Otsubo H, Hwang PA, Hoffman HJ, Becker LE, Gilday DL, Chuang SH, Harwood-Nash D. Neuroimaging studies in children with temporal lobectomy. Childs Nerv Syst. 1995 May; 11(5):281-7. PMID: 7648569.
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    201. Jay V, Becker LE, Otsubo H, Cortez M, Hwang P, Hoffman HJ, Zielenska M. Chronic encephalitis and epilepsy (Rasmussen's encephalitis): detection of cytomegalovirus and herpes simplex virus 1 by the polymerase chain reaction and in situ hybridization. Neurology. 1995 Jan; 45(1):108-17. PMID: 7824098.
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    202. Jay V, Becker LE, Otsubo H, Hwang PA, Hoffman HJ, Harwood-Nash D. Pathology of temporal lobectomy for refractory seizures in children. Review of 20 cases including some unique malformative lesions. J Neurosurg. 1993 Jul; 79(1):53-61. PMID: 8315469.
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    203. Jay V, Becker LE, Otsubo H, Hwang P, Hoffman HJ, Armstrong DC. Neuronal heterotopia with capillary penetration of neurons and cortical dysplasia in a patient with complex partial seizures. Case report. J Neurosurg. 1993 Apr; 78(4):654-7. PMID: 8450340.
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    204. Otsubo H, Hwang PA, Jay V, Becker LE, Hoffman HJ, Gilday D, Blaser S. Focal cortical dysplasia in children with localization-related epilepsy: EEG, MRI, and SPECT findings. Pediatr Neurol. 1993 Mar-Apr; 9(2):101-7. PMID: 8499037.
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    205. Otsubo H, Hoffman HJ, Humphreys RP, Hendrick EB, Drake JM, Hwang PA, Becker LE, Chuang SH. Detection and management of gangliogliomas in children. Surg Neurol. 1992 Nov; 38(5):371-8. PMID: 1485214.
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    206. Otsubo H, Chuang SH, Hwang PA, Gilday D, Hoffman HJ. Neuroimaging for investigation of seizures in children. Pediatr Neurosurg. 1992; 18(2):105-16. PMID: 1419843.
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    207. Hoffman HJ, Otsubo H, Hendrick EB, Humphreys RP, Drake JM, Becker LE, Greenberg M, Jenkin D. Intracranial germ-cell tumors in children. J Neurosurg. 1991 Apr; 74(4):545-51. PMID: 1848284.
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    208. Otsubo H, Hoffman HJ, Humphreys RP, Hendrick EB, Drake JM, Hwang PA, Becker LE, Chuang SH. Evaluation, surgical approach and outcome of seizure patients with gangliogliomas. Pediatr Neurosurg. 1990-1991; 16(4-5):208-12. PMID: 2135188.
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    209. Otsubo H, Takemae T, Inoue T, Kobayashi S, Sugita K. Normovolaemic induced hypertension therapy for cerebral vasospasm after subarachnoid haemorrhage. Acta Neurochir (Wien). 1990; 103(1-2):18-26. PMID: 2360462.
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