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Peter Dirks

TitleStaff Neurosurgeon
InstitutionThe Hospital for Sick Children
DepartmentNeurosurgery
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lee DD, Leão R, Komosa M, Gallo M, Zhang CH, Lipman T, Remke M, Heidari A, Nunes NM, Apolónio JD, Price AJ, De Mello RA, Dias JS, Huntsman D, Hermanns T, Wild PJ, Vanner R, Zadeh G, Karamchandani J, Das S, Taylor MD, Hawkins CE, Wasserman JD, Figueiredo A, Hamilton RJ, Minden MD, Wani K, Diplas B, Yan H, Aldape K, Akbari MR, Danesh A, Pugh TJ, Dirks PB, Castelo-Branco P, Tabori U. DNA hypermethylation within TERT promoter upregulates TERT expression in cancer. J Clin Invest. 2018 Dec 03. PMID: 30358567.
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    2. Tsang DS, Murray L, Ramaswamy V, Zapotocky M, Tabori U, Bartels U, Huang A, Dirks PB, Taylor MD, Hawkins C, Bouffet E, Laperriere N. Craniospinal irradiation as part of re-irradiation for children with recurrent intracranial ependymoma. Neuro Oncol. 2018 Nov 19. PMID: 30452715.
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    3. Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan JJ, Yin WC, Min HK, Hu M, Draghici D, Dou W, Li F, Coutinho FJ, Whetstone H, Kushida MM, Dirks PB, Song Y, Hui CC, Sun Y, Wang LY, Li X, Huang X. A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression. Neuron. 2018 Nov 21; 100(4):799-815.e7. PMID: 30344046.
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    4. Dlamini N, Shah-Basak P, Leung J, Kirkham F, Shroff M, Kassner A, Robertson A, Dirks P, Westmacott R, deVeber G, Logan W. Breath-Hold Blood Oxygen Level-Dependent MRI: A Tool for the Assessment of Cerebrovascular Reserve in Children with Moyamoya Disease. AJNR Am J Neuroradiol. 2018 Sep; 39(9):1717-1723. PMID: 30139753.
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    5. Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018 May 31; 173(6):1549. PMID: 29856958.
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    6. Pasarikovski CR, Abel TJ, Forrest CR, Dirks PB, Ibrahim GM. Delayed Chronic Subdural Hematoma after Total Cranial Vault Reconstruction for Sagittal Synostosis. Pediatr Neurosurg. 2018; 53(3):200-204. PMID: 29672313.
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    7. Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018 Feb 22; 172(5):1050-1062.e14. PMID: 29474906.
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    8. Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN. Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature. 2018 01 04; 553(7686):101-105. PMID: 29258295.
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    9. Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM, Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A. Comprehensive Analysis of Hypermutation in Human Cancer. Cell. 2017 Nov 16; 171(5):1042-1056.e10. PMID: 29056344.
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    10. Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. 2017 09 07; 21(3):411. PMID: 28886368.
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    11. Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida MM, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, Luu B, Carles A, Moksa M, Rastegar N, Head R, Dolma S, Prinos P, Cusimano MD, Das S, Bernstein M, Arrowsmith CH, Mungall AJ, Moore RA, Ma Y, Gallo M, Lupien M, Pugh TJ, Taylor MD, Hirst M, Eaves CJ, Simons BD, Dirks PB. Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy. Nature. 2017 09 14; 549(7671):227-232. PMID: 28854171.
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    12. Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M, Krishnatry R, Guerreiro Stucklin A, Zhukova N, Arnoldo A, Ryall S, Ling C, McKeown T, Loukides J, Cruz O, de Torres C, Ho CY, Packer RJ, Tatevossian R, Qaddoumi I, Harreld JH, Dalton JD, Mulcahy-Levy J, Foreman N, Karajannis MA, Wang S, Snuderl M, Nageswara Rao A, Giannini C, Kieran M, Ligon KL, Garre ML, Nozza P, Mascelli S, Raso A, Mueller S, Nicolaides T, Silva K, Perbet R, Vasiljevic A, Faure Conter C, Frappaz D, Leary S, Crane C, Chan A, Ng HK, Shi ZF, Mao Y, Finch E, Eisenstat D, Wilson B, Carret AS, Hauser P, Sumerauer D, Krskova L, Larouche V, Fleming A, Zelcer S, Jabado N, Rutka JT, Dirks P, Taylor MD, Chen S, Bartels U, Huang A, Ellison DW, Bouffet E, Hawkins C, Tabori U. Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas. J Clin Oncol. 2017 Sep 01; 35(25):2934-2941. PMID: 28727518.
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    13. Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. 2017 08 03; 21(2):209-224.e7. PMID: 28712938.
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    14. Muthusami P, Krings T, Raybaud C, Dirks P, M Shroff M. Intracranial artery to artery spontaneous revascularization in a child. Childs Nerv Syst. 2017 Nov; 33(11):2035-2038. PMID: 28676978.
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    15. Parada LF, Dirks PB, Wechsler-Reya RJ. Brain Tumor Stem Cells Remain in Play. J Clin Oncol. 2017 Jul 20; 35(21):2428-2431. PMID: 28640710.
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    16. Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nor C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, Daniels C, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska WA, Perek-Polnik M, Vasiljevic A, Faure-Conter C, Jouvet A, Giannini C, Nageswara Rao AA, Li KKW, Ng HK, Eberhart CG, Pollack IF, Hamilton RL, Gillespie GY, Olson JM, Leary S, Weiss WA, Lach B, Chambless LB, Thompson RC, Cooper MK, Vibhakar R, Hauser P, van Veelen MC, Kros JM, French PJ, Ra YS, Kumabe T, López-Aguilar E, Zitterbart K, Sterba J, Finocchiaro G, Massimino M, Van Meir EG, Osuka S, Shofuda T, Klekner A, Zollo M, Leonard JR, Rubin JB, Jabado N, Albrecht S, Mora J, Van Meter TE, Jung S, Moore AS, Hallahan AR, Chan JA, Tirapelli DPC, Carlotti CG, Fouladi M, Pimentel J, Faria CC, Saad AG, Massimi L, Liau LM, Wheeler H, Nakamura H, Elbabaa SK, Perezpeña-Diazconti M, Chico Ponce de León F, Robinson S, Zapotocky M, Lassaletta A, Huang A, Hawkins CE, Tabori U, Bouffet E, Bartels U, Dirks PB, Rutka JT, Bader GD, Reimand J, Goldenberg A, Ramaswamy V, Taylor MD. Intertumoral Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 2017 06 12; 31(6):737-754.e6. PMID: 28609654.
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    17. Morrissy AS, Cavalli FMG, Remke M, Ramaswamy V, Shih DJH, Holgado BL, Farooq H, Donovan LK, Garzia L, Agnihotri S, Kiehna EN, Mercier E, Mayoh C, Papillon-Cavanagh S, Nikbakht H, Gayden T, Torchia J, Picard D, Merino DM, Vladoiu M, Luu B, Wu X, Daniels C, Horswell S, Thompson YY, Hovestadt V, Northcott PA, Jones DTW, Peacock J, Wang X, Mack SC, Reimand J, Albrecht S, Fontebasso AM, Thiessen N, Li Y, Schein JE, Lee D, Carlsen R, Mayo M, Tse K, Tam A, Dhalla N, Ally A, Chuah E, Cheng Y, Plettner P, Li HI, Corbett RD, Wong T, Long W, Loukides J, Buczkowicz P, Hawkins CE, Tabori U, Rood BR, Myseros JS, Packer RJ, Korshunov A, Lichter P, Kool M, Pfister SM, Schüller U, Dirks P, Huang A, Bouffet E, Rutka JT, Bader GD, Swanton C, Ma Y, Moore RA, Mungall AJ, Majewski J, Jones SJM, Das S, Malkin D, Jabado N, Marra MA, Taylor MD. Spatial heterogeneity in medulloblastoma. Nat Genet. 2017 May; 49(5):780-788. PMID: 28394352.
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    18. Benifla M, Laughlin S, Tovar-Spinoza ZS, Rutka JT, Dirks PB. Unilateral Postoperative Deep Cerebral Venous Thrombosis with Complete Recovery: A Report of 2 Cases. Pediatr Neurosurg. 2017; 52(3):205-210. PMID: 28324875.
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    19. Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, Planello AC, Zeller C, Barsyte-Lovejoy D, Lafay-Cousin L, Letourneau L, Bourgey M, Yu M, Gendoo DMA, Dzamba M, Barszczyk M, Medina T, Riemenschneider AN, Morrissy AS, Ra YS, Ramaswamy V, Remke M, Dunham CP, Yip S, Ng HK, Lu JQ, Mehta V, Albrecht S, Pimentel J, Chan JA, Somers GR, Faria CC, Roque L, Fouladi M, Hoffman LM, Moore AS, Wang Y, Choi SA, Hansford JR, Catchpoole D, Birks DK, Foreman NK, Strother D, Klekner A, Bognár L, Garami M, Hauser P, Hortobágyi T, Wilson B, Hukin J, Carret AS, Van Meter TE, Hwang EI, Gajjar A, Chiou SH, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheinemann K, Fleming AJ, Johnston DL, Michaud J, Zelcer S, Hammond R, Afzal S, Ramsay DA, Sirachainan N, Hongeng S, Larbcharoensub N, Grundy RG, Lulla RR, Fangusaro JR, Druker H, Bartels U, Grant R, Malkin D, McGlade CJ, Nicolaides T, Tihan T, Phillips J, Majewski J, Montpetit A, Bourque G, Bader GD, Reddy AT, Gillespie GY, Warmuth-Metz M, Rutkowski S, Tabori U, Lupien M, Brudno M, Schüller U, Pietsch T, Judkins AR, Hawkins CE, Bouffet E, Kim SK, Dirks PB, Taylor MD, Erdreich-Epstein A, Arrowsmith CH, De Carvalho DD, Rutka JT, Jabado N, Huang A. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Cancer Cell. 2016 Dec 12; 30(6):891-908. PMID: 27960086.
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    20. Pajtler KW, Mack SC, Ramaswamy V, Smith CA, Witt H, Smith A, Hansford JR, von Hoff K, Wright KD, Hwang E, Frappaz D, Kanemura Y, Massimino M, Faure-Conter C, Modena P, Tabori U, Warren KE, Holland EC, Ichimura K, Giangaspero F, Castel D, von Deimling A, Kool M, Dirks PB, Grundy RG, Foreman NK, Gajjar A, Korshunov A, Finlay J, Gilbertson RJ, Ellison DW, Aldape KD, Merchant TE, Bouffet E, Pfister SM, Taylor MD. The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants. Acta Neuropathol. 2017 01; 133(1):5-12. PMID: 27858204.
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    21. Greb H, Hermann S, Dirks P, Ommen G, Kretschmer V, Schultz K, Zoidl G, Weiler R, Janssen-Bienhold U. Complexity of gap junctions between horizontal cells of the carp retina. Neuroscience. 2017 01 06; 340:8-22. PMID: 27793781.
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    22. Tsitouras V, Wang S, Dirks P, Drake J, Bouffet E, Hawkins C, Laughlin S, Rutka JT. Management and outcome of chordomas in the pediatric population: The Hospital for Sick Children experience and review of the literature. J Clin Neurosci. 2016 Dec; 34:169-176. PMID: 27590862.
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    23. Andrade A, Bigi S, Laughlin S, Parthasarathy S, Sinclair A, Dirks P, Pontigon AM, Moharir M, Askalan R, MacGregor D, deVeber G. Association Between Prolonged Seizures and Malignant Middle Cerebral Artery Infarction in Children With Acute Ischemic Stroke. Pediatr Neurol. 2016 11; 64:44-51. PMID: 27663488.
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    24. Dolma S, Selvadurai HJ, Lan X, Lee L, Kushida M, Voisin V, Whetstone H, So M, Aviv T, Park N, Zhu X, Xu C, Head R, Rowland KJ, Bernstein M, Clarke ID, Bader G, Harrington L, Brumell JH, Tyers M, Dirks PB. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 2016 06 13; 29(6):859-873. PMID: 27300435.
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    25. Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, Lipp ES, Dunham C, Hukin J, Eisenstat DD, Fulton D, van Landeghem FK, Santi M, van Veelen ML, Van Meir EG, Osuka S, Fan X, Muraszko KM, Tirapelli DP, Oba-Shinjo SM, Marie SK, Carlotti CG, Lee JY, Rao AA, Giannini C, Faria CC, Nunes S, Mora J, Hamilton RL, Hauser P, Jabado N, Petrecca K, Jung S, Massimi L, Zollo M, Cinalli G, Bognár L, Klekner A, Hortobágyi T, Leary S, Ermoian RP, Olson JM, Leonard JR, Gardner C, Grajkowska WA, Chambless LB, Cain J, Eberhart CG, Ahsan S, Massimino M, Giangaspero F, Buttarelli FR, Packer RJ, Emery L, Yong WH, Soto H, Liau LM, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis MA, Zagzag D, Wheeler H, von Hoff K, Alonso MM, Tuñon T, Schüller U, Zitterbart K, Sterba J, Chan JA, Guzman M, Elbabaa SK, Colman H, Dhall G, Fisher PG, Fouladi M, Gajjar A, Goldman S, Hwang E, Kool M, Ladha H, Vera-Bolanos E, Wani K, Lieberman F, Mikkelsen T, Omuro AM, Pollack IF, Prados M, Robins HI, Soffietti R, Wu J, Metellus P, Tabori U, Bartels U, Bouffet E, Hawkins CE, Rutka JT, Dirks P, Pfister SM, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Ellison DW, Taylor MD. Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. J Clin Oncol. 2016 07 20; 34(21):2468-77. PMID: 27269943.
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    26. Gallo M, Dirks PB. Global chromatin architecture defines functional cancer hierarchies. Cell Cycle. 2016 08 17; 15(16):2093-2094. PMID: 27247183.
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    27. Saliou G, Dirks P, Slater LA, Krings T. Is jugular bulb stenosis in vein of Galen aneurysmal malformation associated with bony remodeling of the jugular foramina? J Neurosurg Pediatr. 2016 Jul; 18(1):92-6. PMID: 27035549.
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    28. Bouffet E, Larouche V, Campbell BB, Merico D, de Borja R, Aronson M, Durno C, Krueger J, Cabric V, Ramaswamy V, Zhukova N, Mason G, Farah R, Afzal S, Yalon M, Rechavi G, Magimairajan V, Walsh MF, Constantini S, Dvir R, Elhasid R, Reddy A, Osborn M, Sullivan M, Hansford J, Dodgshun A, Klauber-Demore N, Peterson L, Patel S, Lindhorst S, Atkinson J, Cohen Z, Laframboise R, Dirks P, Taylor M, Malkin D, Albrecht S, Dudley RW, Jabado N, Hawkins CE, Shlien A, Tabori U. Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency. J Clin Oncol. 2016 07 01; 34(19):2206-11. PMID: 27001570.
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    29. Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AAN, Giannini C, Li KKW, Ng HK, Yao Y, Kumabe T, Tominaga T, Grajkowska WA, Perek-Polnik M, Low DCY, Seow WT, Chang KTE, Mora J, Pollack IF, Hamilton RL, Leary S, Moore AS, Ingram WJ, Hallahan AR, Jouvet A, Fèvre-Montange M, Vasiljevic A, Faure-Conter C, Shofuda T, Kagawa N, Hashimoto N, Jabado N, Weil AG, Gayden T, Wataya T, Shalaby T, Grotzer M, Zitterbart K, Sterba J, Kren L, Hortobágyi T, Klekner A, László B, Pócza T, Hauser P, Schüller U, Jung S, Jang WY, French PJ, Kros JM, van Veelen MC, Massimi L, Leonard JR, Rubin JB, Vibhakar R, Chambless LB, Cooper MK, Thompson RC, Faria CC, Carvalho A, Nunes S, Pimentel J, Fan X, Muraszko KM, López-Aguilar E, Lyden D, Garzia L, Shih DJH, Kijima N, Schneider C, Adamski J, Northcott PA, Kool M, Jones DTW, Chan JA, Nikolic A, Garre ML, Van Meir EG, Osuka S, Olson JJ, Jahangiri A, Castro BA, Gupta N, Weiss WA, Moxon-Emre I, Mabbott DJ, Lassaletta A, Hawkins CE, Tabori U, Drake J, Kulkarni A, Dirks P, Rutka JT, Korshunov A, Pfister SM, Packer RJ, Ramaswamy V, Taylor MD. Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. Lancet Oncol. 2016 04; 17(4):484-495. PMID: 26976201.
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    30. Krishnatry R, Zhukova N, Guerreiro Stucklin AS, Pole JD, Mistry M, Fried I, Ramaswamy V, Bartels U, Huang A, Laperriere N, Dirks P, Nathan PC, Greenberg M, Malkin D, Hawkins C, Bandopadhayay P, Kieran MW, Manley PE, Bouffet E, Tabori U. Clinical and treatment factors determining long-term outcomes for adult survivors of childhood low-grade glioma: A population-based study. Cancer. 2016 Apr 15; 122(8):1261-9. PMID: 26970559.
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    31. Saliou G, Dirks P, Sacho RH, Chen L, terBrugge K, Krings T. Decreased Superior Sagittal Sinus Diameter and Jugular Bulb Narrowing Are Associated with Poor Clinical Outcome in Vein of Galen Arteriovenous Malformation. AJNR Am J Neuroradiol. 2016 07; 37(7):1354-8. PMID: 26915567.
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    32. Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, Li Y, Mayoh C, Thiessen N, Mercier E, Mungall KL, Ma Y, Tse K, Zeng T, Shumansky K, Roth AJ, Shah S, Farooq H, Kijima N, Holgado BL, Lee JJ, Matan-Lithwick S, Liu J, Mack SC, Manno A, Michealraj KA, Nor C, Peacock J, Qin L, Reimand J, Rolider A, Thompson YY, Wu X, Pugh T, Ally A, Bilenky M, Butterfield YS, Carlsen R, Cheng Y, Chuah E, Corbett RD, Dhalla N, He A, Lee D, Li HI, Long W, Mayo M, Plettner P, Qian JQ, Schein JE, Tam A, Wong T, Birol I, Zhao Y, Faria CC, Pimentel J, Nunes S, Shalaby T, Grotzer M, Pollack IF, Hamilton RL, Li XN, Bendel AE, Fults DW, Walter AW, Kumabe T, Tominaga T, Collins VP, Cho YJ, Hoffman C, Lyden D, Wisoff JH, Garvin JH, Stearns DS, Massimi L, Schüller U, Sterba J, Zitterbart K, Puget S, Ayrault O, Dunn SE, Tirapelli DP, Carlotti CG, Wheeler H, Hallahan AR, Ingram W, MacDonald TJ, Olson JJ, Van Meir EG, Lee JY, Wang KC, Kim SK, Cho BK, Pietsch T, Fleischhack G, Tippelt S, Ra YS, Bailey S, Lindsey JC, Clifford SC, Eberhart CG, Cooper MK, Packer RJ, Massimino M, Garre ML, Bartels U, Tabori U, Hawkins CE, Dirks P, Bouffet E, Rutka JT, Wechsler-Reya RJ, Weiss WA, Collier LS, Dupuy AJ, Korshunov A, Jones DT, Kool M, Northcott PA, Pfister SM, Largaespada DA, Mungall AJ, Moore RA, Jabado N, Bader GD, Jones SJ, Malkin D, Marra MA, Taylor MD. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. 2016 Jan 21; 529(7586):351-7. PMID: 26760213; PMCID: PMC4936195.
    33. Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida MM, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB. MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin. Cancer Cell. 2015 Dec 14; 28(6):715-729. PMID: 26626085.
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    34. Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. 2015 Dec 03; 163(6):1515-26. PMID: 26627737.
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    88. King JA, Armstrong D, Vachhrajani S, Dirks PB. Relative contributions of the middle meningeal artery and superficial temporal artery in revascularization surgery for moyamoya syndrome in children: the results of superselective angiography. J Neurosurg Pediatr. 2010 Feb; 5(2):184-9. PMID: 20121368.
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    89. Li M, Lee KF, Lu Y, Clarke I, Shih D, Eberhart C, Collins VP, Van Meter T, Picard D, Zhou L, Boutros PC, Modena P, Liang ML, Scherer SW, Bouffet E, Rutka JT, Pomeroy SL, Lau CC, Taylor MD, Gajjar A, Dirks PB, Hawkins CE, Huang A. Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell. 2009 Dec 08; 16(6):533-46. PMID: 19962671; PMCID: PMC3431561.
    90. Alexander CM, Puchalski J, Klos KS, Badders N, Ailles L, Kim CF, Dirks P, Smalley MJ. Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell. 2009 Dec 04; 5(6):579-83. PMID: 19951686; PMCID: PMC3076188.
    91. Bhardwaj RD, Auguste KI, Kulkarni AV, Dirks PB, Drake JM, Rutka JT. Management of pediatric brainstem cavernous malformations: experience over 20 years at the hospital for sick children. J Neurosurg Pediatr. 2009 Nov; 4(5):458-64. PMID: 19877780.
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    92. Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov. 2009 Oct; 8(10):806-23. PMID: 19794444.
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    93. Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung AY, Elliott S, Park KJ, Adachi M, Jones FS, Clarke ID, Dirks P, Ellis J. MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PLoS One. 2009 Aug 27; 4(8):e6810. PMID: 19710912; PMCID: PMC2728539.
    94. Dirks PB. MicroRNAs and parallel stem cell lives. Cell. 2009 Aug 07; 138(3):423-4. PMID: 19665962.
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    95. Ahmed I, Auguste KI, Vachhrajani S, Dirks PB, Drake JM, Rutka JT. Neurosurgical management of intracranial epidermoid tumors in children. Clinical article. J Neurosurg Pediatr. 2009 Aug; 4(2):91-6. PMID: 19645539.
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    96. Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell. 2009 Jun 05; 4(6):568-80. PMID: 19497285.
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    97. Ward RJ, Lee L, Graham K, Satkunendran T, Yoshikawa K, Ling E, Harper L, Austin R, Nieuwenhuis E, Clarke ID, Hui CC, Dirks PB. Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma. Cancer Res. 2009 Jun 01; 69(11):4682-90. PMID: 19487286.
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    98. Puget S, Grill J, Valent A, Bieche I, Dantas-Barbosa C, Kauffmann A, Dessen P, Lacroix L, Geoerger B, Job B, Dirven C, Varlet P, Peyre M, Dirks PB, Sainte-Rose C, Vassal G. Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas. J Clin Oncol. 2009 Apr 10; 27(11):1884-92. PMID: 19289631.
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    99. Diamandis P, Sacher AG, Tyers M, Dirks PB. New drugs for brain tumors? Insights from chemical probing of neural stem cells. Med Hypotheses. 2009 Jun; 72(6):683-7. PMID: 19261391.
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    100. King J, Cusimano M, Hawkins C, Dirks P. Extradural middle fossa approach to a clear cell meningioma in a child. Can J Neurol Sci. 2009 Mar; 36(2):257-61. PMID: 19378726.
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    101. Mondal S, Dirks P, Rutka JT. Immunolocalization of fascin, an actin-bundling protein and glial fibrillary acidic protein in human astrocytoma cells. Brain Pathol. 2010 Jan; 20(1):190-9. PMID: 19170683.
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    102. Lo BW, Kulkarni AV, Rutka JT, Jea A, Drake JM, Lamberti-Pasculli M, Dirks PB, Thabane L. Clinical predictors of developmental outcome in patients with cephaloceles. J Neurosurg Pediatr. 2008 Oct; 2(4):254-7. PMID: 18831658.
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    103. Kim CF, Dirks PB. Cancer and stem cell biology: how tightly intertwined? Cell Stem Cell. 2008 Aug 07; 3(2):147-50. PMID: 18682238.
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    104. Dirks PB. Brain tumor stem cells: bringing order to the chaos of brain cancer. J Clin Oncol. 2008 Jun 10; 26(17):2916-24. PMID: 18539973.
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    105. Hutchison JS, Ward RE, Lacroix J, Hébert PC, Barnes MA, Bohn DJ, Dirks PB, Doucette S, Fergusson D, Gottesman R, Joffe AR, Kirpalani HM, Meyer PG, Morris KP, Moher D, Singh RN, Skippen PW. Hypothermia therapy after traumatic brain injury in children. N Engl J Med. 2008 Jun 05; 358(23):2447-56. PMID: 18525042.
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    106. Dirks PB. Cancer's source in the peripheral nervous system. Nat Med. 2008 Apr; 14(4):373-5. PMID: 18391936.
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    107. Otsubo H, Ochi A, Imai K, Akiyama T, Fujimoto A, Go C, Dirks P, Donner EJ. High-frequency oscillations of ictal muscle activity and epileptogenic discharges on intracranial EEG in a temporal lobe epilepsy patient. Clin Neurophysiol. 2008 Apr; 119(4):862-8. PMID: 18289931.
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    108. Sasaki-Adams D, Kulkarni A, Rutka J, Dirks P, Taylor M, Drake JM. Neurosurgical implications of osteogenesis imperfecta in children. Report of 4 cases. J Neurosurg Pediatr. 2008 Mar; 1(3):229-36. PMID: 18352768.
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    109. Dirks PB. Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells. Philos Trans R Soc Lond B Biol Sci. 2008 Jan 12; 363(1489):139-52. PMID: 17309866; PMCID: PMC2605491.
    110. Dirks P. Bmi1 and cell of origin determinants of brain tumor phenotype. Cancer Cell. 2007 Oct; 12(4):295-7. PMID: 17936553.
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    111. Jea A, Al-Otibi M, Rutka JT, Drake JM, Dirks PB, Kulkarni AV, Taylor MD, Humphreys RP. The history of neurosurgery at the Hospital for Sick Children in Toronto. Neurosurgery. 2007 Sep; 61(3):612-24; discussion 624-5. PMID: 17881976.
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    112. Jea A, Taylor MD, Dirks PB, Kulkarni AV, Rutka JT, Drake JM. Incorporation of C-1 lateral mass screws in occipitocervical and atlantoaxial fusions for children 8 years of age or younger. Technical note. J Neurosurg. 2007 Aug; 107(2 Suppl):178-83. PMID: 18459894.
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    113. Depreitere B, Dasi N, Rutka J, Dirks P, Drake J. Endoscopic biopsy for intraventricular tumors in children. J Neurosurg. 2007 May; 106(5 Suppl):340-6. PMID: 17566198.
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    114. Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007 May; 3(5):268-73. PMID: 17417631.
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    115. Hune SY, deVeber GA, MacGregor DL, Dirks PB, Yu HW, Soman TB, Allen A, Golomb MR. Nursing issues in caring for children with moyamoya vasculopathy and their families. J Neurosci Nurs. 2007 Feb; 39(1):33-9. PMID: 17396536.
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    116. Singh S, Dirks PB. Brain tumor stem cells: identification and concepts. Neurosurg Clin N Am. 2007 Jan; 18(1):31-8, viii. PMID: 17244552.
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    117. Ward RJ, Dirks PB. Cancer stem cells: at the headwaters of tumor development. Annu Rev Pathol. 2007; 2:175-89. PMID: 18039097.
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    118. Dirks PB. Cancer: stem cells and brain tumours. Nature. 2006 Dec 07; 444(7120):687-8. PMID: 17151644.
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    119. Zadeh G, Andrade-Souza YM, Tsao MN, Scora D, Armstrong D, Humphreys R, Rutka J, Drake J, Dirks P, Schwartz ML. Pediatric arteriovenous malformation: University of Toronto experience using stereotactic radiosurgery. Childs Nerv Syst. 2007 Feb; 23(2):195-9. PMID: 17115227.
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    120. Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, Visvader J, Weissman IL, Wahl GM. Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res. 2006 Oct 01; 66(19):9339-44. PMID: 16990346.
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    121. Balenci L, Clarke ID, Dirks PB, Assard N, Ducray F, Jouvet A, Belin MF, Honnorat J, Baudier J. IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme. Cancer Res. 2006 Sep 15; 66(18):9074-82. PMID: 16982749.
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    122. Mohamed IS, Otsubo H, Pang E, Chuang SH, Rutka JT, Dirks P, Weiss SK, Snead OC. Magnetoencephalographic spike sources associated with auditory auras in paediatric localisation-related epilepsy. J Neurol Neurosurg Psychiatry. 2006 Nov; 77(11):1256-61. PMID: 16891385; PMCID: PMC2077384.
    123. Edwards RJ, Dirks PB. Gelfoam obstruction of endoscopic third ventriculostomy. Case illustration. J Neurosurg. 2006 Aug; 105(2 Suppl):154. PMID: 16922080.
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    124. Rafay MF, Smith SE, Dirks P, Armstrong D, deVeber GA. Hemorrhage predisposing to cerebral infarction in children with moyamoya disease. Pediatr Neurol. 2006 May; 34(5):400-4. PMID: 16648003.
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    125. Bartels U, Hawkins C, Jing M, Ho M, Dirks P, Rutka J, Stephens D, Bouffet E. Vascularity and angiogenesis as predictors of growth in optic pathway/hypothalamic gliomas. J Neurosurg. 2006 May; 104(5 Suppl):314-20. PMID: 16848088.
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    126. Khanani MF, Hawkins C, Shroff M, Dirks P, Capra M, Burger PC, Bouffet E. Pilomyxoid astrocytoma in a patient with neurofibromatosis. Pediatr Blood Cancer. 2006 Mar; 46(3):377-80. PMID: 15800886.
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    127. Araki T, Drake JM, Rutka JT, Dirks PB, Yokota H, Yamamoto Y. [Clinical diagnosis and treatment of pediatric head trauma]. No Shinkei Geka. 2006 Feb; 34(2):135-46. PMID: 16485559.
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    128. Hutchison J, Ward R, Lacroix J, Hébert P, Skippen P, Barnes M, Meyer P, Morris K, Kirpalani H, Singh R, Dirks P, Bohn D, Moher D. Hypothermia pediatric head injury trial: the value of a pretrial clinical evaluation phase. Dev Neurosci. 2006; 28(4-5):291-301. PMID: 16943652.
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    129. Gnanaraj L, Gilliland MG, Yahya RR, Rutka JT, Drake J, Dirks P, Levin AV. Ocular manifestations of crush head injury in children. Eye (Lond). 2007 Jan; 21(1):5-10. PMID: 16311527.
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    130. Yahya RR, Dirks P, Humphreys R, Rutka JT, Taylor M, Drake JM. Children and television tipovers: a significant and preventable cause of long-term neurological deficits. J Neurosurg. 2005 Sep; 103(3 Suppl):219-22. PMID: 16238074.
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    131. Mikulis DJ, Krolczyk G, Desal H, Logan W, Deveber G, Dirks P, Tymianski M, Crawley A, Vesely A, Kassner A, Preiss D, Somogyi R, Fisher JA. Preoperative and postoperative mapping of cerebrovascular reactivity in moyamoya disease by using blood oxygen level-dependent magnetic resonance imaging. J Neurosurg. 2005 Aug; 103(2):347-55. PMID: 16175867.
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    132. Agid R, Souza MP, Reintamm G, Armstrong D, Dirks P, TerBrugge KG. The role of endovascular treatment for pediatric aneurysms. Childs Nerv Syst. 2005 Dec; 21(12):1030-6. PMID: 15864599.
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    133. Dirks PB. Brain tumor stem cells. Biol Blood Marrow Transplant. 2005 Feb; 11(2 Suppl 2):12-3. PMID: 15682168.
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    134. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature. 2004 Nov 18; 432(7015):396-401. PMID: 15549107.
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    135. Kulkarni AV, Drake JM, Rabin D, Dirks PB, Humphreys RP, Rutka JT. Measuring the health status of children with hydrocephalus by using a new outcome measure. J Neurosurg. 2004 Nov; 101(2 Suppl):141-6. PMID: 15835100.
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    136. Singh SK, Clarke ID, Hide T, Dirks PB. Cancer stem cells in nervous system tumors. Oncogene. 2004 Sep 20; 23(43):7267-73. PMID: 15378086.
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    137. Punnett AS, McCarthy LJ, Dirks PB, Hawkins C, Bouffet E. Patients with primary brain tumors as organ donors: case report and review of the literature. Pediatr Blood Cancer. 2004 Jul; 43(1):73-7. PMID: 15170894.
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    138. Capra M, Wherrett D, Weitzman S, Dirks P, Hawkins C, Bouffet E. Pituitary stalk thickening and primary central nervous system lymphoma. J Neurooncol. 2004 Mar-Apr; 67(1-2):227-31. PMID: 15072472.
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    139. Al-Gahtany M, Shroff M, Bouffet E, Dirks P, Drake J, Humphreys R, Laperriere N, Hawkins C, Rutka J, Shroft M. Primary central nervous system sarcomas in children: clinical, radiological, and pathological features. Childs Nerv Syst. 2003 Dec; 19(12):808-17. PMID: 14574612.
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    140. Chuang NA, Shroff MM, Willinsky RA, Drake JM, Dirks PB, Armstrong DC. Slow-flow spinal epidural AVF with venous ectasias: two pediatric case reports. AJNR Am J Neuroradiol. 2003 Oct; 24(9):1901-5. PMID: 14561625.
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    141. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003 Sep 15; 63(18):5821-8. PMID: 14522905.
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    142. Clarke ID, Dirks PB. A human brain tumor-derived PDGFR-alpha deletion mutant is transforming. Oncogene. 2003 Feb 06; 22(5):722-33. PMID: 12569364.
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    143. Langlois A, Lee S, Kim DS, Dirks PB, Rutka JT. p16(ink4a) and retinoic acid modulate rhoA and GFAP expression during induction of a stellate phenotype in U343 MG-A astrocytoma cells. Glia. 2002 Oct; 40(1):85-94. PMID: 12237846.
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    144. Lo PA, Drake JM, Hedden D, Narotam P, Dirks PB. Avulsion transverse ligament injuries in children: successful treatment with nonoperative management. Report of three cases. J Neurosurg. 2002 Apr; 96(3 Suppl):338-42. PMID: 11990844.
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    145. Carlotti CG, Salhia B, Weitzman S, Greenberg M, Dirks PB, Mason W, Becker LE, Rutka JT. Evaluation of proliferative index and cell cycle protein expression in choroid plexus tumors in children. Acta Neuropathol. 2002 Jan; 103(1):1-10. PMID: 11837741.
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    146. Dirks PB. Glioma migration: clues from the biology of neural progenitor cells and embryonic CNS cell migration. J Neurooncol. 2001 Jun; 53(2):203-12. PMID: 11716071.
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    147. Murakami M, Dirks PB, Hubbard SL, Rutka JT. Cytoskeletal-induced alterations in the adhesion of HT-1080 fibrosarcoma cells to extracellular matrix. Int J Oncol. 2001 May; 18(5):1027-33. PMID: 11295052.
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    148. Mainprize TG, Taylor MD, Rutka JT, Dirks PB. Cip/Kip cell-cycle inhibitors: a neuro-oncological perspective. J Neurooncol. 2001 Feb; 51(3):205-18. PMID: 11407593.
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    149. Ivanchuk SM, Mondal S, Dirks PB, Rutka JT. The INK4A/ARF locus: role in cell cycle control and apoptosis and implications for glioma growth. J Neurooncol. 2001 Feb; 51(3):219-29. PMID: 11407594.
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    150. Tsugu A, Sakai K, Dirks PB, Jung S, Weksberg R, Fei YL, Mondal S, Ivanchuk S, Ackerley C, Hamel PA, Rutka JT. Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence. Am J Pathol. 2000 Sep; 157(3):919-32. PMID: 10980131; PMCID: PMC1885689.
    151. Kulkarni AV, Drake JM, Armstrong DC, Dirks PB. Imaging correlates of successful endoscopic third ventriculostomy. J Neurosurg. 2000 Jun; 92(6):915-9. PMID: 10839249.
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    152. Rutka JT, Taylor M, Mainprize T, Langlois A, Ivanchuk S, Mondal S, Dirks P. Molecular biology and neurosurgery in the third millennium. Neurosurgery. 2000 May; 46(5):1034-51. PMID: 10807235.
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    153. Rutka JT, Ivanchuk S, Mondal S, Taylor M, Sakai K, Dirks P, Jun P, Jung S, Becker LE, Ackerley C. Co-expression of nestin and vimentin intermediate filaments in invasive human astrocytoma cells. Int J Dev Neurosci. 1999 Aug-Oct; 17(5-6):503-15. PMID: 10571412.
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    154. Kulkarni AV, Drake JM, Armstrong DC, Dirks PB. Measurement of ventricular size: reliability of the frontal and occipital horn ratio compared to subjective assessment. Pediatr Neurosurg. 1999 Aug; 31(2):65-70. PMID: 10592474.
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    155. Rutka JT, Muller M, Hubbard SL, Forsdike J, Dirks PB, Jung S, Tsugu A, Ivanchuk S, Costello P, Mondal S, Ackerley C, Becker LE. Astrocytoma adhesion to extracellular matrix: functional significance of integrin and focal adhesion kinase expression. J Neuropathol Exp Neurol. 1999 Feb; 58(2):198-209. PMID: 10029102.
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    156. Arab S, Murakami M, Dirks P, Boyd B, Hubbard SL, Lingwood CA, Rutka JT. Verotoxins inhibit the growth of and induce apoptosis in human astrocytoma cells. J Neurooncol. 1998 Nov; 40(2):137-50. PMID: 9892096.
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    157. Dirks PB, Rutka JT, Hubbard SL, Mondal S, Hamel PA. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells. Oncogene. 1998 Aug 20; 17(7):867-76. PMID: 9780003.
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    158. Rutka JT, Ackerley C, Hubbard SL, Tilup A, Dirks PB, Jung S, Ivanchuk S, Kurimoto M, Tsugu A, Becker LE. Characterization of glial filament-cytoskeletal interactions in human astrocytomas: an immuno-ultrastructural analysis. Eur J Cell Biol. 1998 Aug; 76(4):279-87. PMID: 9765058.
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    159. Dirks PB, Patel K, Hubbard SL, Ackerley C, Hamel PA, Rutka JT. Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells. Oncogene. 1997 Oct 23; 15(17):2037-48. PMID: 9366521.
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    160. Rutka JT, Murakami M, Dirks PB, Hubbard SL, Becker LE, Fukuyama K, Jung S, Tsugu A, Matsuzawa K. Role of glial filaments in cells and tumors of glial origin: a review. J Neurosurg. 1997 Sep; 87(3):420-30. PMID: 9285609.
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    161. Tsugu A, Dirks P, Jung S, Kurimoto M, Jay V, Murakami M, Rutka JT. Cell cycle control in pediatric neuro-oncology. Pediatr Neurosurg. 1997 May; 26(5):226-35. PMID: 9440492.
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    162. Dirks PB, Rutka JT. Current concepts in neuro-oncology: the cell cycle--a review. Neurosurgery. 1997 May; 40(5):1000-13; discussion 1013-5. PMID: 9149259.
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    163. Dirks PB, Hubbard SL, Murakami M, Rutka JT. Cyclin and cyclin-dependent kinase expression in human astrocytoma cell lines. J Neuropathol Exp Neurol. 1997 Mar; 56(3):291-300. PMID: 9056543.
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    164. Matsuzawa K, Fukuyama K, Dirks PB, Hubbard S, Murakami M, Becker LE, Rutka JT. Expression of stromelysin 1 in human astrocytoma cell lines. J Neurooncol. 1996 Dec; 30(3):181-8. PMID: 8943093.
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    165. Murakami M, Fukuyama K, Hubbard S, Matsuzawa K, Dirks PB, Rutka JT. Inducible expression of glial fibrillary acidic protein in HT-1080 human fibrosarcoma cells. Cell Growth Differ. 1996 Dec; 7(12):1697-703. PMID: 8959338.
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    166. Dirks PB, Harris L, Hoffman HJ, Humphreys RP, Drake JM, Rutka JT. Supratentorial primitive neuroectodermal tumors in children. J Neurooncol. 1996 Jul; 29(1):75-84. PMID: 8817418.
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    167. Sidle A, Palaty C, Dirks P, Wiggan O, Kiess M, Gill RM, Wong AK, Hamel PA. Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation. Crit Rev Biochem Mol Biol. 1996 Jun; 31(3):237-71. PMID: 8817077.
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    168. Fukuyama K, Matsuzawa K, Hubbard SL, Dirks PB, Murakami M, Rutka JT. Analysis of glial fibrillary acidic protein gene methylation in human malignant gliomas. Anticancer Res. 1996 May-Jun; 16(3A):1251-7. PMID: 8702246.
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    169. Matsuzawa K, Fukuyama K, Hubbard SL, Dirks PB, Rutka JT. Transfection of an invasive human astrocytoma cell line with a TIMP-1 cDNA: modulation of astrocytoma invasive potential. J Neuropathol Exp Neurol. 1996 Jan; 55(1):88-96. PMID: 8558175.
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    170. Squire JA, Thorner PS, Weitzman S, Maggi JD, Dirks P, Doyle J, Hale M, Godbout R. Co-amplification of MYCN and a DEAD box gene (DDX1) in primary neuroblastoma. Oncogene. 1995 Apr 06; 10(7):1417-22. PMID: 7731693.
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    171. Rutka J, Matsuzawa K, Hubbard S, Fukuyama K, Becker L, Stetlerstevenson W, Edwards D, Dirks P. Expression of timp-1, timp-2, 72-kda and 92-kda type-iv collagenase transcripts in human astrocytoma cell-lines - correlation with astrocytoma cell invasiveness. Int J Oncol. 1995 Apr; 6(4):877-84. PMID: 21556615.
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    172. Muller M, Hubbard SL, Fukuyama K, Dirks P, Matsuzawa K, Rutka JT. Characterization of a pineal region malignant rhabdoid tumor. Towards understanding brain tumor cell invasion. Pediatr Neurosurg. 1995; 22(4):204-9. PMID: 7619721.
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    173. Rutka JT, Hubbard SL, Fukuyama K, Matsuzawa K, Dirks PB, Becker LE. Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells. Cancer Res. 1994 Jun 15; 54(12):3267-72. PMID: 8205549.
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    174. Dirks PB, Jay V, Becker LE, Drake JM, Humphreys RP, Hoffman HJ, Rutka JT. Development of anaplastic changes in low-grade astrocytomas of childhood. Neurosurgery. 1994 Jan; 34(1):68-78. PMID: 8121571.
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    175. Dirks P, Bernstein M, Muller PJ, Tucker WS. The value of reoperation for recurrent glioblastoma. Can J Surg. 1993 Jun; 36(3):271-5. PMID: 8391917.
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    176. James AL, Dirks P, Ohtaka H, Schellenberg RR, Hogg JC. Airway responsiveness to intravenous and inhaled acetylcholine in the guinea pig after cigarette smoke exposure. Am Rev Respir Dis. 1987 Nov; 136(5):1158-62. PMID: 3674578.
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    177. Friedenberg WR, Dirks P, Beltaos E, Mazza JJ, Hoehn JL, Greenlaw RH, Russ HH, Schloesser LL. Improved survival in the treatment of advanced Hodgkin's disease at a nonuniversity institution (1970-1979). Cancer. 1986 Jan 01; 57(1):12-7. PMID: 3753582.
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