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Tilman Humpl

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentCritical Care Medicine
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Beghetti M, Brand M, Berger RMF, Humpl T, Wheeler JG, Ivy DD, Bonnet D. Meaningful and feasible composite clinical worsening definitions in paediatric pulmonary arterial hypertension: An analysis of the TOPP registry. Int J Cardiol. 2019 Apr 25. PMID: 31072635.
      View in: PubMed
    2. Humpl T, Honjo O, Temple M, de Perrot M. Pulmonary endarterectomy in a toddler with chronic thromboembolic pulmonary hypertension after Denver shunt. J Thorac Cardiovasc Surg. 2019 Mar 02. PMID: 30952537.
      View in: PubMed
    3. Miera O, Morales DLS, Thul J, Amodeo A, Menon AK, Humpl T. Improvement of survival in low-weight children on the Berlin Heart EXCOR ventricular assist device support. Eur J Cardiothorac Surg. 2018 Dec 22. PMID: 30590433.
      View in: PubMed
    4. Pelland-Marcotte MC, Humpl T, James PD, Rand ML, Bouskill V, Reyes JT, Bowman ML, Carcao MD. Idiopathic pulmonary arterial hypertension - a unrecognized cause of high-shear high-flow haemostatic defects (otherwise referred to as acquired von Willebrand syndrome) in children. Br J Haematol. 2018 Oct; 183(2):267-275. PMID: 30141279.
      View in: PubMed
    5. Lammers AE, Humpl T. Use of pulmonary vasodilators in Fontan patients: a useful strategy to improve functional status and delay transplantation? Pulm Circ. 2018 Jul-Sep; 8(3):2045894018798616. PMID: 30124131.
      View in: PubMed
    6. Brown G, Humpl T. Approach to pulmonary vascular disease in the ICU. Curr Opin Pediatr. 2018 06; 30(3):326-331. PMID: 29528890.
      View in: PubMed
    7. Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH. The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension. J Pediatr. 2018 06; 197:17-22. PMID: 29628412.
      View in: PubMed
    8. Wong M, Reyes J, Lapidus-Krol E, Chiang M, Humpl T, Al-Faraj M, Ryan G, Chiu PPL. Pulmonary hypertension in congenital diaphragmatic hernia patients: Prognostic markers and long-term outcomes. J Pediatr Surg. 2018 May; 53(5):918-924. PMID: 29502796.
      View in: PubMed
    9. Luo S, Foreman C, Sano M, Soto Agüero MJ, Guerguerian AM, Kirsch R, Humpl T, Huang L, Honjo O. Novel Leg Cannula for Venous Decompression in Peripheral Extracorporeal Membrane Oxygenation. Ann Thorac Surg. 2018 Feb; 105(2):e95-e97. PMID: 29362203.
      View in: PubMed
    10. Bin-Hasan S, Khayat A, Humpl T, Reyes JT, Al-Saleh S. Resolution of Periodic Breathing in a Child with Idiopathic Pulmonary Arterial Hypertension. Case Rep Pediatr. 2017; 2017:3280572. PMID: 29071163.
      View in: PubMed
    11. Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH. Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 09; 188:24-34.e1. PMID: 28645441.
      View in: PubMed
    12. Lam CZ, Bhamare TA, Gazzaz T, Manson D, Humpl T, Seed M. Diagnosis of secondary pulmonary lymphangiectasia in congenital heart disease: a novel role for chest ultrasound and prognostic implications. Pediatr Radiol. 2017 Oct; 47(11):1441-1451. PMID: 28631156.
      View in: PubMed
    13. Katz SL, Luu TM, Nuyt AM, Lacaze T, Adamo KB, Adatia I, Humpl T, Jankov RP, Moraes TJ, Staub K, Stickland MK, Thebaud B. Long-term follow-up of cardiorespiratory outcomes in children born extremely preterm: Recommendations from a Canadian consensus workshop. Paediatr Child Health. 2017 May; 22(2):75-79. PMID: 29479185.
      View in: PubMed
    14. Jaquiss RD, Humpl T, Canter CE, Morales DL, Rosenthal DN, Fraser CD. Postapproval Outcomes: The Berlin Heart EXCOR Pediatric in North America. ASAIO J. 2017 Mar/Apr; 63(2):193-197. PMID: 28234657.
      View in: PubMed
    15. Laskine-Holland ML, Kahr WH, Crawford-Lean L, Humpl T, Honjo O, Foreman C, Jain M, O'Leary JD. The Association Between Cyanosis and Thromboelastometry (ROTEM) in Children With Congenital Heart Defects: A Retrospective Cohort Study. Anesth Analg. 2017 01; 124(1):23-29. PMID: 27861436.
      View in: PubMed
    16. Humpl T, Berger RMF, Austin ED, Fasnacht Boillat MS, Bonnet D, Ivy DD, Zuk M, Beghetti M, Schulze-Neick I. Treatment initiation in paediatric pulmonary hypertension: insights from a multinational registry. Cardiol Young. 2017 Aug; 27(6):1123-1132. PMID: 27995825.
      View in: PubMed
    17. Buompadre MC, Andres K, Slater LA, Mohseni-Bod H, Guerguerian AM, Branson H, Laughlin S, Armstrong D, Moharir M, deVeber G, Humpl T, Honjo O, Keshavjee S, Ichord R, Pereira V, Dlamini N. Thrombectomy for Acute Stroke in Childhood: A Case Report, Literature Review, and Recommendations. Pediatr Neurol. 2017 01; 66:21-27. PMID: 27769730.
      View in: PubMed
    18. Caro-Domínguez P, Compton G, Humpl T, Manson DE. Pulmonary arterial hypertension in children: diagnosis using ratio of main pulmonary artery to ascending aorta diameter as determined by multi-detector computed tomography. Pediatr Radiol. 2016 Sep; 46(10):1378-83. PMID: 27194438.
      View in: PubMed
    19. Douwes JM, Humpl T, Bonnet D, Beghetti M, Ivy DD, Berger RM. Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry. J Am Coll Cardiol. 2016 Mar 22; 67(11):1312-23. PMID: 26988953.
      View in: PubMed
    20. Ploegstra MJ, Ivy DD, Wheeler JG, Brand M, Beghetti M, Rosenzweig EB, Humpl T, Iriart X, Rouzic EM, Bonnet D, Berger RM. Growth in children with pulmonary arterial hypertension: a longitudinal retrospective multiregistry study. Lancet Respir Med. 2016 04; 4(4):281-90. PMID: 26994897.
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    21. Del Cerro MJ, Moledina S, Haworth SG, Ivy D, Al Dabbagh M, Banjar H, Diaz G, Heath-Freudenthal A, Galal AN, Humpl T, Kulkarni S, Lopes A, Mocumbi AO, Puri GD, Rossouw B, Harikrishnan S, Saxena A, Udo P, Caicedo L, Tamimi O, Adatia I. Cardiac catheterization in children with pulmonary hypertensive vascular disease: consensus statement from the Pulmonary Vascular Research Institute, Pediatric and Congenital Heart Disease Task Forces. Pulm Circ. 2016 Mar; 6(1):118-25. PMID: 27076908.
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    22. Beghetti M, Berger RM, Ivy DD, Bonnet D, Humpl T. To "Cath" or Not in Pediatric Pulmonary Hypertension? J Am Coll Cardiol. 2016 Mar 01; 67(8):1010-1. PMID: 26916495.
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    23. King SK, Alfaraj M, Gaiteiro R, O'Brien K, Moraes T, Humpl T, Marcon M, Chiang M, Reyes J, Haliburton B, Ryan G, Cox P, Chiu PP. Congenital diaphragmatic hernia: Observed/expected lung-to-head ratio as a predictor of long-term morbidity. J Pediatr Surg. 2016 May; 51(5):699-702. PMID: 26932249.
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    24. Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4. PMID: 26703869.
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    25. Compton GL, Florence J, MacDonald C, Yoo SJ, Humpl T, Manson D. Main Pulmonary Artery-to-Ascending Aorta Diameter Ratio in Healthy Children on MDCT. AJR Am J Roentgenol. 2015 Dec; 205(6):1322-5. PMID: 26587940.
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    26. Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. PMID: 26534956.
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    27. Beghetti M, Schulze-Neick I, Berger RM, Ivy DD, Bonnet D, Weintraub RG, Saji T, Yung D, Mallory GB, Geiger R, Berger JT, Barst RJ, Humpl T. Haemodynamic characterisation and heart catheterisation complications in children with pulmonary hypertension: Insights from the Global TOPP Registry (tracking outcomes and practice in paediatric pulmonary hypertension). Int J Cardiol. 2016 Jan 15; 203:325-30. PMID: 26583838.
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    28. Zafar F, Jefferies JL, Tjossem CJ, Bryant R, Jaquiss RD, Wearden PD, Rosenthal DN, Cabrera AG, Rossano JW, Humpl T, Morales DL. Biventricular Berlin Heart EXCOR pediatric use across the united states. Ann Thorac Surg. 2015 Apr; 99(4):1328-34. PMID: 25704863.
      View in: PubMed
    29. Jordan LC, Ichord RN, Reinhartz O, Humpl T, Pruthi S, Tjossem C, Rosenthal DN. Neurological complications and outcomes in the Berlin Heart EXCOR® pediatric investigational device exemption trial. J Am Heart Assoc. 2015 Jan 22; 4(1):e001429. PMID: 25613996.
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    30. Conway J, St Louis J, Morales DL, Law S, Tjossem C, Humpl T. Delineating survival outcomes in children <10 kg bridged to transplant or recovery with the Berlin Heart EXCOR Ventricular Assist Device. JACC Heart Fail. 2015 Jan; 3(1):70-7. PMID: 25454394.
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    31. Okumura K, Humpl T, Dragulescu A, Mertens L, Friedberg MK. Longitudinal assessment of right ventricular myocardial strain in relation to transplant-free survival in children with idiopathic pulmonary hypertension. J Am Soc Echocardiogr. 2014 Dec; 27(12):1344-51. PMID: 25306221.
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    32. Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC. Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium. Pediatr Neurol. 2015 Jan; 52(1):5-15. PMID: 25532775.
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    33. Woerner C, Cutz E, Yoo SJ, Grasemann H, Humpl T. Pulmonary venoocclusive disease in childhood. Chest. 2014 Jul; 146(1):167-174. PMID: 24503954.
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    34. Murthy S, MacDonald C, Honjo O, Floh AA, Humpl T. Innominate artery aneurysm after cannulation for extracorporeal membrane oxygenation via the right carotid artery. Intensive Care Med. 2013 Nov; 39(11):2038-9. PMID: 23963473.
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    35. Kassem E, Humpl T, Friedberg MK. Prognostic significance of 2-dimensional, M-mode, and Doppler echo indices of right ventricular function in children with pulmonary arterial hypertension. Am Heart J. 2013 Jun; 165(6):1024-31. PMID: 23708176.
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    36. Beghetti M, Berger RM, Schulze-Neick I, Day RW, Pulido T, Feinstein J, Barst RJ, Humpl T. Diagnostic evaluation of paediatric pulmonary hypertension in current clinical practice. Eur Respir J. 2013 Sep; 42(3):689-700. PMID: 23563261.
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    37. Almond CS, Morales DL, Blackstone EH, Turrentine MW, Imamura M, Massicotte MP, Jordan LC, Devaney EJ, Ravishankar C, Kanter KR, Holman W, Kroslowitz R, Tjossem C, Thuita L, Cohen GA, Buchholz H, St Louis JD, Nguyen K, Niebler RA, Walters HL, Reemtsen B, Wearden PD, Reinhartz O, Guleserian KJ, Mitchell MB, Bleiweis MS, Canter CE, Humpl T. Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children. Circulation. 2013 Apr 23; 127(16):1702-11. PMID: 23538380.
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    38. Floh AA, La Rotta G, Wermelt JZ, Bastero-Miñón P, Sivarajan VB, Humpl T. Validation of a new method based on ultrasound velocity dilution to measure cardiac output in paediatric patients. Intensive Care Med. 2013 May; 39(5):926-33. PMID: 23430016.
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    39. Abman SH, Kinsella JP, Rosenzweig EB, Krishnan U, Kulik T, Mullen M, Wessel DL, Steinhorn R, Adatia I, Hanna B, Feinstein J, Fineman J, Raj U, Humpl T. Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension. Am J Respir Crit Care Med. 2013 Mar 15; 187(6):572-5. PMID: 23220921.
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    40. Schechter T, Leucht S, Bouffet E, Cutz E, Gassas A, Huang A, Bartels U, Humpl T, Doyle J. Pulmonary hypertensive vasculopathy following tandem autologous transplantation in pediatric patients with central nervous system tumors. Biol Blood Marrow Transplant. 2013 Feb; 19(2):235-9. PMID: 23022389.
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    41. Fraser CD, Jaquiss RD, Rosenthal DN, Humpl T, Canter CE, Blackstone EH, Naftel DC, Ichord RN, Bomgaars L, Tweddell JS, Massicotte MP, Turrentine MW, Cohen GA, Devaney EJ, Pearce FB, Carberry KE, Kroslowitz R, Almond CS. Prospective trial of a pediatric ventricular assist device. N Engl J Med. 2012 Aug 09; 367(6):532-41. PMID: 22873533.
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    42. Apitz C, Honjo O, Humpl T, Li J, Assad RS, Cho MY, Hong J, Friedberg MK, Redington AN. Biventricular structural and functional responses to aortic constriction in a rabbit model of chronic right ventricular pressure overload. J Thorac Cardiovasc Surg. 2012 Dec; 144(6):1494-501. PMID: 22818124.
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    43. Bastero-Miñón P, Russell JL, Humpl T. Frequency, characteristics, and outcomes of pediatric patients readmitted to the cardiac critical care unit. Intensive Care Med. 2012 Aug; 38(8):1352-7. PMID: 22588651.
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    44. Berger RM, Beghetti M, Humpl T, Raskob GE, Ivy DD, Jing ZC, Bonnet D, Schulze-Neick I, Barst RJ. Clinical features of paediatric pulmonary hypertension: a registry study. Lancet. 2012 Feb 11; 379(9815):537-46. PMID: 22240409.
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    45. Apitz C, Honjo O, Friedberg MK, Assad RS, Van Arsdell G, Humpl T, Redington AN. Beneficial effects of vasopressors on right ventricular function in experimental acute right ventricular failure in a rabbit model. Thorac Cardiovasc Surg. 2012 Feb; 60(1):17-23. PMID: 22222683.
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    46. Sajan I, Manlhiot C, Reyes J, McCrindle BW, Humpl T, Friedberg MK. Pulmonary arterial capacitance in children with idiopathic pulmonary arterial hypertension and pulmonary arterial hypertension associated with congenital heart disease: relation to pulmonary vascular resistance, exercise capacity, and survival. Am Heart J. 2011 Sep; 162(3):562-8. PMID: 21884877.
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    47. Morales DL, Almond CS, Jaquiss RD, Rosenthal DN, Naftel DC, Massicotte MP, Humpl T, Turrentine MW, Tweddell JS, Cohen GA, Kroslowitz R, Devaney EJ, Canter CE, Fynn-Thompson F, Reinhartz O, Imamura M, Ghanayem NS, Buchholz H, Furness S, Mazor R, Gandhi SK, Fraser CD. Bridging children of all sizes to cardiac transplantation: the initial multicenter North American experience with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant. 2011 Jan; 30(1):1-8. PMID: 21145473.
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    48. Humpl T, Reyes JT, Erickson S, Armano R, Holtby H, Adatia I. Sildenafil therapy for neonatal and childhood pulmonary hypertensive vascular disease. Cardiol Young. 2011 Apr; 21(2):187-93. PMID: 21138617.
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    49. Jeewa A, Manlhiot C, McCrindle BW, Van Arsdell G, Humpl T, Dipchand AI. Outcomes with ventricular assist device versus extracorporeal membrane oxygenation as a bridge to pediatric heart transplantation. Artif Organs. 2010 Dec; 34(12):1087-91. PMID: 20545660.
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    50. Humpl T, Furness S, Gruenwald C, Hyslop C, Van Arsdell G. The Berlin Heart EXCOR Pediatrics-The SickKids Experience 2004-2008. Artif Organs. 2010 Dec; 34(12):1082-6. PMID: 20545666.
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    51. Humpl T, Reineker K, Manlhiot C, Dipchand AI, Coles JG, McCrindle BW. Cor triatriatum sinistrum in childhood. A single institution's experience. Can J Cardiol. 2010 Aug-Sep; 26(7):371-6. PMID: 20847964.
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    52. Alkon J, Humpl T, Manlhiot C, McCrindle BW, Reyes JT, Friedberg MK. Usefulness of the right ventricular systolic to diastolic duration ratio to predict functional capacity and survival in children with pulmonary arterial hypertension. Am J Cardiol. 2010 Aug 01; 106(3):430-6. PMID: 20643259.
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    53. Apitz C, Reyes JT, Holtby H, Humpl T, Redington AN. Pharmacokinetic and hemodynamic responses to oral sildenafil during invasive testing in children with pulmonary hypertension. J Am Coll Cardiol. 2010 Apr 06; 55(14):1456-62. PMID: 20359596.
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    54. Walsh MA, Asoh K, Van Arsdell GS, Humpl T. Critical care outcomes in pulmonary atresia and intact ventricular septum undergoing single-ventricle palliation. Cardiol Young. 2010 Jun; 20(3):290-6. PMID: 20307330.
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    55. Giglia TM, Humpl T. Preoperative pulmonary hemodynamics and assessment of operability: is there a pulmonary vascular resistance that precludes cardiac operation? Pediatr Crit Care Med. 2010 Mar; 11(2 Suppl):S57-69. PMID: 20216166.
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    56. Rosenzweig EB, Feinstein JA, Humpl T, Ivy DD. Pulmonary arterial hypertension in children: Diagnostic work-up and challenges. Prog Pediatr Cardiol. 2009 Dec; 27(1):4-11. PMID: 21691442.
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    57. Ivy DD, Feinstein JA, Humpl T, Rosenzweig EB. Non-congenital heart disease associated pediatric pulmonary arterial hypertension. Prog Pediatr Cardiol. 2009 Dec 01; 27(1-2):13-23. PMID: 21852894.
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    58. Asoh K, Hickey E, Dorostkar PC, Chaturvedi R, van Arsdell G, Humpl T, Benson LN. Outcomes of emergent cardiac catheterization following pediatric cardiac surgery. Catheter Cardiovasc Interv. 2009 Jun 01; 73(7):933-40. PMID: 19180662.
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    59. Smith G, Reyes JT, Russell JL, Humpl T. Safety of maximal cardiopulmonary exercise testing in pediatric patients with pulmonary hypertension. Chest. 2009 May; 135(5):1209-1214. PMID: 19118264.
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    60. Furness S, Hyslop-St George C, Pound B, Earle M, Maurich A, Rice D, Humpl T. Development of an interprofessional pediatric ventricular assist device support team. ASAIO J. 2008 Sep-Oct; 54(5):483-5. PMID: 18812738.
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    61. Wermelt JZ, Honjo O, Kilic A, van Arsdell G, Gruenwald C, Humpl T. Use of a pulsatile ventricular assist device (Berlin Heart EXCOR) and an interventional lung assist device (Novalung) in an animal model. ASAIO J. 2008 Sep-Oct; 54(5):498-503. PMID: 18812741.
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    62. Jerath N, Frndova H, McCrindle BW, Gurofsky R, Humpl T. Clinical impact of vasopressin infusion on hemodynamics, liver and renal function in pediatric patients. Intensive Care Med. 2008 Jul; 34(7):1274-80. PMID: 18350274.
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    63. Li J, Zhang G, Herridge J, Holtby H, Humpl T, Redington AN, Van Arsdell GS. Energy expenditure and caloric and protein intake in infants following the Norwood procedure. Pediatr Crit Care Med. 2008 Jan; 9(1):55-61. PMID: 18477914.
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    64. Li J, Zhang G, Holtby H, Guerguerian AM, Cai S, Humpl T, Caldarone CA, Redington AN, Van Arsdell GS. The influence of systemic hemodynamics and oxygen transport on cerebral oxygen saturation in neonates after the Norwood procedure. J Thorac Cardiovasc Surg. 2008 Jan; 135(1):83-90, 90.e1-2. PMID: 18179923.
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    65. Li J, Zhang G, Benson L, Holtby H, Cai S, Humpl T, Van Arsdell GS, Redington AN, Caldarone CA. Comparison of the profiles of postoperative systemic hemodynamics and oxygen transport in neonates after the hybrid or the Norwood procedure: a pilot study. Circulation. 2007 Sep 11; 116(11 Suppl):I179-87. PMID: 17846301.
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    66. Hansmann G, Humpl T, Zimmermann A, Bührer C, Wauer R, Stannigel H, Hoehn T. [ILCOR's new resuscitation guidelines in preterm and term infants: critical discussion and suggestions for implementation]. Klin Padiatr. 2007 Mar-Apr; 219(2):50-7. PMID: 17373592.
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    67. Li J, Zhang G, McCrindle BW, Holtby H, Humpl T, Cai S, Caldarone CA, Redington AN, Van Arsdell GS. Profiles of hemodynamics and oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure. J Thorac Cardiovasc Surg. 2007 Feb; 133(2):441-8. PMID: 17258581.
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    68. Li J, Zhang G, Holtby H, Humpl T, Caldarone CA, Van Arsdell GS, Redington AN. Adverse effects of dopamine on systemic hemodynamic status and oxygen transport in neonates after the Norwood procedure. J Am Coll Cardiol. 2006 Nov 07; 48(9):1859-64. PMID: 17084263.
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    69. Katz SL, Adatia I, Louca E, Leung K, Humpl T, Reyes JT, Coates AL. Nebulized therapies for childhood pulmonary hypertension: an in vitro model. Pediatr Pulmonol. 2006 Jul; 41(7):666-73. PMID: 16703580.
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    70. Li J, Van Arsdell GS, Zhang G, Cai S, Humpl T, Caldarone CA, Holtby H, Redington AN. Assessment of the relationship between cerebral and splanchnic oxygen saturations measured by near-infrared spectroscopy and direct measurements of systemic haemodynamic variables and oxygen transport after the Norwood procedure. Heart. 2006 Nov; 92(11):1678-85. PMID: 16621884.
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    71. Li J, Zhang G, Holtby HM, McCrindle BW, Cai S, Humpl T, Caldarone CA, Williams WG, Redington AN, Van Arsdell GS. Inclusion of oxygen consumption improves the accuracy of arterial and venous oxygen saturation interpretation after the Norwood procedure. J Thorac Cardiovasc Surg. 2006 May; 131(5):1099-107. PMID: 16678596.
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    72. Humpl T, Zaidi SH, Coe JY, Russell J, Kaneda Y, Massaeli H, Benson LN, Rabinovitch M. Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct. Pediatr Res. 2005 Nov; 58(5):976-80. PMID: 16183805.
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    73. Humpl T, Reyes JT, Holtby H, Stephens D, Adatia I. Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension: twelve-month clinical trial of a single-drug, open-label, pilot study. Circulation. 2005 Jun 21; 111(24):3274-80. PMID: 15956137.
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    74. Hansmann G, Humpl T, Zimmermann A. [Neonatal-emergencies: basics in cardiopulmonary resuscitation]. Z Geburtshilfe Neonatol. 2004 Apr; 208(2):43-56. PMID: 15112137.
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    75. Bartels U, Hargrave D, Lau L, Esquembre C, Humpl T, Bouffet E. [Analysis of paediatric neuro-oncological information on the Internet in German language]. Klin Padiatr. 2003 Nov-Dec; 215(6):352-7. PMID: 14677102.
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    76. Humpl T, Söderberg B, McCrindle BW, Nykanen DG, Freedom RM, Williams WG, Benson LN. Percutaneous balloon valvotomy in pulmonary atresia with intact ventricular septum: impact on patient care. Circulation. 2003 Aug 19; 108(7):826-32. PMID: 12885744.
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    77. Humpl T, McCrindle BW, Smallhorn JF. The relative roles of transthoracic compared with transesophageal echocardiography in children with suspected infective endocarditis. J Am Coll Cardiol. 2003 Jun 04; 41(11):2068-71. PMID: 12798583.
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    78. Humpl T, Campbell R, Stephens D, Van Arsdell G, Benson LN, Holtby HM, Slutsky AS, Adatia I. Levels of exhaled nitric oxide before and after surgical and transcatheter device closure of atrial septal defects in children. J Thorac Cardiovasc Surg. 2002 Oct; 124(4):806-10. PMID: 12324740.
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    79. Lee KJ, Humpl T, Hashmi A, Nykanen DG, Williams WG, Benson LN. Restoration of aortopulmonary shunt patency. Am J Cardiol. 2001 Aug 01; 88(3):325-8. PMID: 11472721.
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    80. Humpl T, Thüroff JW, Gutjahr P. Paediatric urological malignancies. BJU Int. 2001 May; 87(8):741-6. PMID: 11350429.
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    81. Humpl T, Neuser H, Brühl K, Bartels U, Schwarz M, Gutjahr P. Clinical aspects and prognosis of ependymoma in infants and children. A single institution experience. Childs Nerv Syst. 2001 Apr; 17(4-5):246-51. PMID: 11398944.
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    82. Brühl K, Stoeter P, Wietek B, Schwarz M, Humpl T, Schumacher R, Spranger J. Cerebral spinal fluid flow, venous drainage and spinal cord compression in achondroplastic children: impact of magnetic resonance findings for decompressive surgery at the cranio-cervical junction. Eur J Pediatr. 2001 Jan; 160(1):10-20. PMID: 11195012.
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    83. Humpl T, Fritsche M, Bartels U, Gutjahr P. Survivors of childhood cancer for more than twenty years. Acta Oncol. 2001; 40(1):44-9. PMID: 11321659.
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    84. Cowan KN, Heilbut A, Humpl T, Lam C, Ito S, Rabinovitch M. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med. 2000 Jun; 6(6):698-702. PMID: 10835689.
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    85. Humpl T, Huggan P, Hornberger LK, McCrindle BW. Presentation and outcomes of ectopia cordis. Can J Cardiol. 1999 Dec; 15(12):1353-7. PMID: 10620741.
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    86. Humpl T, Brühl K, Brzezinska R, Hafner G, Coerdt W, Shearer MJ. Fatal late vitamin K-deficiency bleeding after oral vitamin K prophylaxis secondary to unrecognized bile duct paucity. J Pediatr Gastroenterol Nutr. 1999 Nov; 29(5):594-7. PMID: 10554130.
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    87. Humpl T, Schramm P, Gutjahr P. Male fertility in long-term survivors of childhood ALL. Arch Androl. 1999 Sep-Oct; 43(2):123-9. PMID: 10543574.
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    88. Humpl T, Gutjahr P. Paediatric oncology. Curr Opin Urol. 1998 Nov; 8(6):525-8. PMID: 17039070.
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    89. Humpl T, Brühl K, Pitz S, de Mooy P, Bartels U, Gutjahr P. [Rhabdomyosarcoma of the orbits in childhood]. Ophthalmologe. 1997 Dec; 94(12):914-9. PMID: 9487763.
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    90. Humpl T, Brühl K, Bohl J, Schwarz M, Stoeter P, Gutjahr P. Cerebral haemorrhage in long-term survivors of childhood acute lymphoblastic leukaemia. Eur J Pediatr. 1997 May; 156(5):367-70. PMID: 9177978.
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    91. Gutjahr P, Humpl T. Testicular lymphoblastic leukemia/lymphoma. World J Urol. 1995; 13(4):230-2. PMID: 8528297.
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    92. Humpl T. Neuroblastoma. World J Urol. 1995; 13(4):233-9. PMID: 8528298.
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