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Khosrow Adeli

TitleHead, Clinical Biochemistry Division
InstitutionThe Hospital for Sick Children
DepartmentPaediatric Laboratory Medicine (PLM)
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Parker ML, Adeli K. Pediatric and adult reference interval harmonization in Canada: an update. Clin Chem Lab Med. 2018 Dec 19; 57(1):57-60. PMID: 29303773.
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    2. Ozarda Y, Higgins V, Adeli K. Verification of reference intervals in routine clinical laboratories: practical challenges and recommendations. Clin Chem Lab Med. 2018 Dec 19; 57(1):30-37. PMID: 29729142.
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    3. Alvares D, Hoffman S, Stankovic B, Adeli K. Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Dec 19; 1864(3):326-334. PMID: 30578967.
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    4. Tahmasebi H, Higgins V, Woroch A, Asgari S, Adeli K. Pediatric reference intervals for clinical chemistry assays on Siemens ADVIA XPT/1800 and Dimension EXL in the CALIPER cohort of healthy children and adolescents. Clin Chim Acta. 2018 Dec 12; 490:88-97. PMID: 30550936.
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    5. Xu XR, Wang Y, Adili R, Ju L, Spring CM, Jin JW, Yang H, Neves MAD, Chen P, Yang Y, Lei X, Chen Y, Gallant RC, Xu M, Zhang H, Song J, Ke P, Zhang D, Carrim N, Yu SY, Zhu G, She YM, Cyr T, Fu W, Liu G, Connelly PW, Rand ML, Adeli K, Freedman J, Lee JE, Tso P, Marchese P, Davidson WS, Jackson SP, Zhu C, Ruggeri ZM, Ni H. Apolipoprotein A-IV binds aIIbß3 integrin and inhibits thrombosis. Nat Commun. 2018 09 06; 9(1):3608. PMID: 30190457.
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    6. Taher J, Baker C, Alvares D, Ijaz L, Hussain M, Adeli K. GLP-2 Dysregulates Hepatic Lipoprotein Metabolism, Inducing Fatty Liver and VLDL Overproduction in Male Hamsters and Mice. Endocrinology. 2018 Sep 01; 159(9):3340-3350. PMID: 30052880.
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    7. Maghsudi M, Shahabadi N, Kooshk MRA, Ghaemi N, Nemati L, Parvaneh S, Adeli K, Varmira K. Nontoxic silver nanocluster-induced folding, fibrillation, and aggregation of blood plasma proteins. Int J Biol Macromol. 2018 Nov; 119:838-848. PMID: 30067958.
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    8. Higgins V, Asgari S, Chan MK, Adeli K. Pediatric reference intervals for calculated LDL cholesterol, non-HDL cholesterol, and remnant cholesterol in the healthy CALIPER cohort. Clin Chim Acta. 2018 Nov; 486:129-134. PMID: 30025755.
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    9. Tahmasebi H, Trajcevski K, Higgins V, Adeli K. Influence of ethnicity on population reference values for biochemical markers. Crit Rev Clin Lab Sci. 2018 Aug; 55(5):359-375. PMID: 29874957.
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    10. Adeli K, Higgins V, Trajcevski K, Palmert MR. Important considerations for interpreting biochemical tests in children. BMJ. 2018 May 24; 361:k1950. PMID: 29798834.
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    11. Higgins V, Truong D, White-Al Habeeb NMA, Fung AWS, Hoffman B, Adeli K. Pediatric reference intervals for 1,25-dihydroxyvitamin D using the DiaSorin LIAISON XL assay in the healthy CALIPER cohort. Clin Chem Lab Med. 2018 May 24; 56(6):964-972. PMID: 29389662.
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    12. Higgins V, Adeli K. Pediatric decision limits for lipid parameters in the Brazilian population. J Pediatr (Rio J). 2018 May 17. PMID: 29777649.
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    13. Parker ML, Adeli K, Lévy É, Delvin E. Are universal upper reference limits for alanine aminotransferase (ALT) appropriate for assessing pediatric liver injury? Clin Biochem. 2018 Mar; 53:55-57. PMID: 29366877.
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    14. Hoffman S, Adeli K. LDL Receptor Gene-Ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia with Dominant Inheritance and Diet-Induced Coronary Atherosclerosis. EBioMedicine. 2018 Feb; 28:17-18. PMID: 29396304.
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    15. Higgins V, Fung AWS, Chan MK, Macri J, Adeli K. Pediatric reference intervals for 29 Ortho VITROS 5600 immunoassays using the CALIPER cohort of healthy children and adolescents. Clin Chem Lab Med. 2018 01 26; 56(2):327-340. PMID: 28723610.
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    16. Higgins V, Truong D, Woroch A, Chan MK, Tahmasebi H, Adeli K. CLSI-based transference and verification of CALIPER pediatric reference intervals for 29 Ortho VITROS 5600 chemistry assays. Clin Biochem. 2018 Mar; 53:93-103. PMID: 29307782.
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    17. Khound R, Taher J, Baker C, Adeli K, Su Q. GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2252-2259. PMID: 29074588.
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    18. Adeli K, Higgins V, Trajcevski K, White-Al Habeeb N. The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper. Crit Rev Clin Lab Sci. 2017 09; 54(6):358-413. PMID: 29017389.
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    19. Higgins V, Adeli K. Postprandial Dyslipidemia: Pathophysiology and Cardiovascular Disease Risk Assessment. EJIFCC. 2017 Oct; 28(3):168-184. PMID: 29075168.
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    20. Zamani M, Taher J, Adeli K. Complex role of autophagy in regulation of hepatic lipid and lipoprotein metabolism. J Biomed Res. 2017 Sep 26; 31(5):377-385. PMID: 27346467.
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    21. Parkin PC, Hamid J, Borkhoff CM, Abdullah K, Atenafu EG, Birken CS, Maguire JL, Azad A, Higgins V, Adeli K. Laboratory reference intervals in the assessment of iron status in young children. BMJ Paediatr Open. 2017; 1(1):e000074. PMID: 29637115.
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    22. Persaud N, Ziai H, Lebovic G, Maguire JL, Khovratovich M, Simpson JAR, Adeli K, Hamilton J, McCrindle BW, Parkin PC, Birken CS. Parent reported nutritional risk and laboratory indices of cardiometabolic risk and in preschool-aged children. J Pediatr Endocrinol Metab. 2017 Aug 28; 30(8):839-846. PMID: 28723611.
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    23. Daly CH, Higgins V, Adeli K, Grey VL, Hamid JS. Reference interval estimation: Methodological comparison using extensive simulations and empirical data. Clin Biochem. 2017 Dec; 50(18):1145-1158. PMID: 28733190.
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    24. Abbasi Oshaghi E, Goodarzi MT, Higgins V, Adeli K. Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action. Crit Rev Clin Lab Sci. 2017 06; 54(4):267-293. PMID: 28704113.
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    25. Haynes RL, Frelinger AL, Giles EK, Goldstein RD, Tran H, Kozakewich HP, Haas EA, Gerrits AJ, Mena OJ, Trachtenberg FL, Paterson DS, Berry GT, Adeli K, Kinney HC, Michelson AD. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7695-7700. PMID: 28674018.
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    26. Adeli K, Higgins V, Seccombe D, Collier CP, Balion CM, Cembrowski G, Venner AA, Shaw J. National Survey of Adult and Pediatric Reference Intervals in Clinical Laboratories across Canada: A Report of the CSCC Working Group on Reference Interval Harmonization. Clin Biochem. 2017 Nov; 50(16-17):925-935. PMID: 28647526.
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    27. Anderson LN, Heong SW, Chen Y, Thorpe KE, Adeli K, Howard A, Sochett E, Birken CS, Parkin PC, Maguire JL. Vitamin D and Fracture Risk in Early Childhood: A Case-Control Study. Am J Epidemiol. 2017 06 15; 185(12):1255-1262. PMID: 28459987.
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    28. Panteghini M, Adeli K, Ceriotti F, Sandberg S, Horvath AR. American Liver Guidelines and Cutoffs for "Normal" ALT: A Potential for Overdiagnosis. Clin Chem. 2017 Jul; 63(7):1196-1198. PMID: 28515102.
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    29. Adeli K. Laboratory medicine - A hidden treasure in healthcare. Clin Biochem. 2017 Aug; 50(12):645-647. PMID: 28363751.
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    30. Higgins V, Adeli K. Pediatric Metabolic Syndrome: Pathophysiology and Laboratory Assessment. EJIFCC. 2017 Mar; 28(1):25-42. PMID: 28439217.
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    31. Tahmasebi H, Higgins V, Fung AWS, Truong D, White-Al Habeeb NMA, Adeli K. Pediatric Reference Intervals for Biochemical Markers: Gaps and Challenges, Recent National Initiatives and Future Perspectives. EJIFCC. 2017 Mar; 28(1):43-63. PMID: 28439218.
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    32. Higgins V, Chan MK, Adeli K. Pediatric Reference Intervals for Transferrin Saturation in the CALIPER Cohort of Healthy Children and Adolescents. EJIFCC. 2017 Mar; 28(1):77-84. PMID: 28439220.
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    33. Zhang J, Zamani M, Thiele C, Taher J, Amir Alipour M, Yao Z, Adeli K. AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion. Arterioscler Thromb Vasc Biol. 2017 04; 37(4):633-642. PMID: 28183703.
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    34. Cagman Z, Bingol Ozakpinar O, Cirakli Z, Gedikbasi A, Ay P, Colantonio D, Uras AR, Adeli K, Uras F. Reference intervals for growth arrest-specific 6 protein in adults. Scand J Clin Lab Invest. 2017 Apr; 77(2):109-114. PMID: 28150505.
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    35. Taher J, Farr S, Adeli K. Central nervous system regulation of hepatic lipid and lipoprotein metabolism. Curr Opin Lipidol. 2017 02; 28(1):32-38. PMID: 27906714.
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    36. Anderson LN, Maguire JL, Lebovic G, Hanley AJ, Hamilton J, Adeli K, McCrindle BW, Borkhoff CM, Parkin PC, Birken CS. Duration of Fasting, Serum Lipids, and Metabolic Profile in Early Childhood. J Pediatr. 2017 01; 180:47-52.e1. PMID: 27742126.
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    37. Adeli K. Corrigendum to "Higgins V, Chan MK, Nieuwesteeg M, Hoffman BR, Bromberg IL, Gornall D, Randell E, Adeli K. Transference of CALIPER pediatric reference intervals to biochemical assays on the Roche Cobas 6000 and the Roche Modular P." [Clin. Biochem. 2016 49(1):139-49]. Clin Biochem. 2016 Oct; 49(15):1210. PMID: 27717483.
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    38. Raizman JE, Shea J, Daly CH, Karbasy K, Ariadne P, Chen Y, Henderson T, Redmond S, Silverman S, Moore AM, Adeli K. Clinical impact of improved point-of-care glucose monitoring in neonatal intensive care using Nova StatStrip: Evidence for improved accuracy, better sensitivity, and reduced test utilization. Clin Biochem. 2016 Aug; 49(12):879-84. PMID: 27157715.
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    39. Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochim Biophys Acta. 2016 Jul; 1861(7):594-605. PMID: 27090939.
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    40. Karbasy K, Lin DC, Stoianov A, Chan MK, Bevilacqua V, Chen Y, Adeli K. Pediatric reference value distributions and covariate-stratified reference intervals for 29 endocrine and special chemistry biomarkers on the Beckman Coulter Immunoassay Systems: a CALIPER study of healthy community children. Clin Chem Lab Med. 2016 Apr; 54(4):643-57. PMID: 26457782.
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    41. Tate JR, Koerbin G, Adeli K. Opinion Paper: Deriving Harmonised Reference Intervals - Global Activities. EJIFCC. 2016 Feb; 27(1):48-65. PMID: 27683506.
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    42. Farr S, Taher J, Adeli K. Central nervous system regulation of intestinal lipid and lipoprotein metabolism. Curr Opin Lipidol. 2016 Feb; 27(1):1-7. PMID: 26628437.
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    43. Ali SA, Al-Jazrawe M, Ma H, Whetstone H, Poon R, Farr S, Naples M, Adeli K, Alman BA. Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. Arthritis Rheumatol. 2016 Jan; 68(1):127-37. PMID: 26315393; PMCID: PMC4690757.
    44. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652.
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    45. Kelishadi R, Marateb HR, Mansourian M, Ardalan G, Heshmat R, Adeli K. Pediatric-specific reference intervals in a nationally representative sample of Iranian children and adolescents: the CASPIAN-III study. World J Pediatr. 2016 Aug; 12(3):335-342. PMID: 26684311.
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    46. Raizman JE, Quinn F, Armbruster DA, Adeli K. Pediatric reference intervals for calculated free testosterone, bioavailable testosterone and free androgen index in the CALIPER cohort. Clin Chem Lab Med. 2015 Sep 01; 53(10):e239-43. PMID: 25883205.
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    47. Kelly J, Raizman JE, Bevilacqua V, Chan MK, Chen Y, Quinn F, Shodin B, Armbruster D, Adeli K. Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents. Clin Chim Acta. 2015 Oct 23; 450:196-202. PMID: 26310965.
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    48. Higgins V, Chan MK, Nieuwesteeg M, Hoffman BR, Bromberg IL, Gornall D, Randell E, Adeli K. Transference of CALIPER pediatric reference intervals to biochemical assays on the Roche cobas 6000 and the Roche Modular P. Clin Biochem. 2016 Jan; 49(1-2):139-49. PMID: 26297116.
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    49. Gorgani-Firuzjaee S, Khatami S, Adeli K, Meshkani R. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):1028-1033. PMID: 26188518.
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    50. Lino M, Farr S, Baker C, Fuller M, Trigatti B, Adeli K. Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 01; 309(5):G350-9. PMID: 26138463.
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    51. Hsieh J, Trajcevski KE, Farr SL, Baker CL, Lake EJ, Taher J, Iqbal J, Hussain MM, Adeli K. Glucagon-Like Peptide 2 (GLP-2) Stimulates Postprandial Chylomicron Production and Postabsorptive Release of Intestinal Triglyceride Storage Pools via Induction of Nitric Oxide Signaling in Male Hamsters and Mice. Endocrinology. 2015 Oct; 156(10):3538-47. PMID: 26132919.
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    52. Xiao C, Dash S, Morgantini C, Adeli K, Lewis GF. Gut Peptides Are Novel Regulators of Intestinal Lipoprotein Secretion: Experimental and Pharmacological Manipulation of Lipoprotein Metabolism. Diabetes. 2015 Jul; 64(7):2310-8. PMID: 26106188.
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    53. Gorgani-Firuzjaee S, Adeli K, Meshkani R. Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells. Biochem Biophys Res Commun. 2015 Aug 21; 464(2):441-6. PMID: 26123392.
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    54. Araújo PA, Thomas D, Sadeghieh T, Bevilacqua V, Chan MK, Chen Y, Randell E, Adeli K. CLSI-based transference of the CALIPER database of pediatric reference intervals to Beckman Coulter DxC biochemical assays. Clin Biochem. 2015 Sep; 48(13-14):870-80. PMID: 26070714.
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    55. Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Biochemical marker reference values across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug; 61(8):1049-62. PMID: 26044506.
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    56. Adeli K, Higgins V, Nieuwesteeg M, Raizman JE, Chen Y, Wong SL, Blais D. Complex reference values for endocrine and special chemistry biomarkers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug; 61(8):1063-74. PMID: 26044507.
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    57. Adeli K, Raizman JE, Chen Y, Higgins V, Nieuwesteeg M, Abdelhaleem M, Wong SL, Blais D. Complex biological profile of hematologic markers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015 Aug; 61(8):1075-86. PMID: 26044509.
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    58. Abou El Hassan M, Stoianov A, Araújo PA, Sadeghieh T, Chan MK, Chen Y, Randell E, Nieuwesteeg M, Adeli K. CLSI-based transference of CALIPER pediatric reference intervals to Beckman Coulter AU biochemical assays. Clin Biochem. 2015 Nov; 48(16-17):1151-9. PMID: 25979809.
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    59. Teodoro-Morrison T, Kyriakopoulou L, Chen YK, Raizman JE, Bevilacqua V, Chan MK, Wan B, Yazdanpanah M, Schulze A, Adeli K. Dynamic biological changes in metabolic disease biomarkers in childhood and adolescence: A CALIPER study of healthy community children. Clin Biochem. 2015 Sep; 48(13-14):828-36. PMID: 25977068.
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    60. Loverdos I, Swan MC, Shekherdimian S, Al-Rasheed AA, Schneider R, Fish JS, Ngan BY, Adeli K, Lowe ME, Singh VP, Sevilla WM, Langer JC, Gonska T. A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition. J Pediatr Surg Case Rep. 2015 May; 3(5):223-226. PMID: 27182490.
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    61. Farr S, Baker C, Naples M, Taher J, Iqbal J, Hussain M, Adeli K. Central Nervous System Regulation of Intestinal Lipoprotein Metabolism by Glucagon-Like Peptide-1 via a Brain-Gut Axis. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1092-100. PMID: 25675997.
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    62. Devgun MS, Chan MK, El-Nujumi AM, Abara R, Armbruster D, Adeli K. Clinical decision limits for interpretation of direct bilirubin--a CALIPER study of healthy multiethnic children and case report reviews. Clin Biochem. 2015 Jan; 48(1-2):93-6. PMID: 25445233.
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    63. Kelly J, Sadeghieh T, Adeli K. Peer Review in Scientific Publications: Benefits, Critiques, & A Survival Guide. EJIFCC. 2014 Oct; 25(3):227-43. PMID: 27683470.
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    64. Kavsak PA, Rezanpour A, Chen Y, Adeli K. Assessment of the 99th or 97.5th percentile for cardiac troponin I in a healthy pediatric cohort. Clin Chem. 2014 Dec; 60(12):1574-6. PMID: 25336718.
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    65. Karbasy K, Ariadne P, Gaglione S, Nieuwesteeg M, Adeli K. Advances in Pediatric Reference Intervals for Biochemical Markers: Establishment of the Caliper Database in Healthy Children and Adolescents. J Med Biochem. 2015 Jan; 34(1):23-30. PMID: 28356820.
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    66. Taher J, Baker CL, Cuizon C, Masoudpour H, Zhang R, Farr S, Naples M, Bourdon C, Pausova Z, Adeli K. GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance. Mol Metab. 2014 Dec; 3(9):823-33. PMID: 25506548; PMCID: PMC4264039.
    67. Bevilacqua V, Chan MK, Chen Y, Armbruster D, Schodin B, Adeli K. Pediatric population reference value distributions for cancer biomarkers and covariate-stratified reference intervals in the CALIPER cohort. Clin Chem. 2014 Dec; 60(12):1532-42. PMID: 25261558.
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    68. Markle JG, Frank DN, Adeli K, von Bergen M, Danska JS. Microbiome manipulation modifies sex-specific risk for autoimmunity. Gut Microbes. 2014 Jul 01; 5(4):485-93. PMID: 25007153.
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    69. Adeli K. Closing the gaps in pediatric reference intervals: an update on the CALIPER project. Clin Biochem. 2014 Jun; 47(9):737-9. PMID: 24858208.
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    70. Su Q, Baker C, Christian P, Naples M, Tong X, Zhang K, Santha M, Adeli K. Hepatic mitochondrial and ER stress induced by defective PPARa signaling in the pathogenesis of hepatic steatosis. Am J Physiol Endocrinol Metab. 2014 Jun 01; 306(11):E1264-73. PMID: 24735884; PMCID: PMC4280162.
    71. Raizman JE, Cohen AH, Teodoro-Morrison T, Wan B, Khun-Chen M, Wilkenson C, Bevilaqua V, Adeli K. Pediatric reference value distributions for vitamins A and E in the CALIPER cohort and establishment of age-stratified reference intervals. Clin Biochem. 2014 Jun; 47(9):812-5. PMID: 24726493.
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    145. Schnabl KL, Sibbald M, Gold WL, Chan PC, Adeli K. A patient with a leg rash, pedal edema, renal failure, and thrombocytopenia. Clin Chem. 2009 Jul; 55(7):1419-22; discussion 1423-4. PMID: 19561221.
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    146. Basciano H, Miller AE, Naples M, Baker C, Kohen R, Xu E, Su Q, Allister EM, Wheeler MB, Adeli K. Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E462-73. PMID: 19509184.
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    147. Meshkani R, Adeli K. Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clin Biochem. 2009 Sep; 42(13-14):1331-46. PMID: 19501581.
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    148. Basciano H, Miller A, Baker C, Naples M, Adeli K. LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. Am J Physiol Gastrointest Liver Physiol. 2009 Aug; 297(2):G323-32. PMID: 19497957.
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    149. Hsieh J, Longuet C, Maida A, Bahrami J, Xu E, Baker CL, Brubaker PL, Drucker DJ, Adeli K. Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36. Gastroenterology. 2009 Sep; 137(3):997-1005, 1005.e1-4. PMID: 19482026.
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    150. Simoneau-Roy J, O'Gorman C, Pencharz P, Adeli K, Daneman D, Hamilton J. Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma. Clin Endocrinol (Oxf). 2010 Mar; 72(3):364-70. PMID: 19486023.
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    151. Rose JB, Ellis L, John B, Martin S, Gonska T, Solomon M, Tullis E, Corey M, Adeli K, Durie PR. Does the Macroduct collection system reliably define sweat chloride concentration in subjects with intermediate results? Clin Biochem. 2009 Aug; 42(12):1260-4. PMID: 19445912.
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    152. Qiu W, Su Q, Rutledge AC, Zhang J, Adeli K. Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling. J Lipid Res. 2009 Sep; 50(9):1814-23. PMID: 19383982; PMCID: PMC2724794.
    153. Sirek AS, Liu L, Naples M, Adeli K, Ng DS, Jin T. Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1. Endocrinology. 2009 Aug; 150(8):3483-92. PMID: 19359385.
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    154. Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1287-98. PMID: 19342510.
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    155. Li H, Adeli K. Laboratory quality regulations and accreditation standards in Canada. Clin Biochem. 2009 Mar; 42(4-5):249-55. PMID: 19863915.
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    156. Chan MK, Seiden-Long I, Aytekin M, Quinn F, Ravalico T, Ambruster D, Adeli K. Canadian Laboratory Initiative on Pediatric Reference Interval Database (CALIPER): pediatric reference intervals for an integrated clinical chemistry and immunoassay analyzer, Abbott ARCHITECT ci8200. Clin Biochem. 2009 Jun; 42(9):885-91. PMID: 19318027.
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    157. Rutledge AC, Qiu W, Zhang R, Kohen-Avramoglu R, Nemat-Gorgani N, Adeli K. Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus. Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4):579-85. PMID: 19164805.
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    158. Wong DM, Adeli K. Microsomal proteomics. Methods Mol Biol. 2009; 519:273-89. PMID: 19381589.
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    159. Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K. Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. Hepatology. 2008 Dec; 48(6):1799-809. PMID: 19026012; PMCID: PMC4544759.
    160. Qin B, Polansky MM, Sato Y, Adeli K, Anderson RA. Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals. J Nutr Biochem. 2009 Nov; 20(11):901-8. PMID: 18993048.
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    161. Adeli K. eJIFCC Special Issue on Laboratory Reference Intervals. EJIFCC. 2008 Oct; 19(2):94. PMID: 27683303.
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    162. Schnabl K, Chan MK, Adeli K. 3. Pediatric Reference Intervals: Critical Gap Analysis and Establishment of a National Initiative. EJIFCC. 2008 Oct; 19(2):115-22. PMID: 27683306.
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    163. Schnabl K, Chan MK, Gong Y, Adeli K. Closing the gaps in paediatric reference intervals: the CALIPER initiative. Clin Biochem Rev. 2008 Aug; 29(3):89-96. PMID: 19107221.
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    164. Hsieh J, Hayashi AA, Webb J, Adeli K. Postprandial dyslipidemia in insulin resistance: mechanisms and role of intestinal insulin sensitivity. Atheroscler Suppl. 2008 Sep; 9(2):7-13. PMID: 18653387.
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    165. Adeli K, Lewis GF. Intestinal lipoprotein overproduction in insulin-resistant states. Curr Opin Lipidol. 2008 Jun; 19(3):221-8. PMID: 18460911.
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    166. Collins KL, Roberts EA, Adeli K, Bohn D, Harvey EA. Single pass albumin dialysis (SPAD) in fulminant Wilsonian liver failure: a case report. Pediatr Nephrol. 2008 Jun; 23(6):1013-6. PMID: 18299897.
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    167. Qin B, Anderson RA, Adeli K. Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1120-9. PMID: 18372392.
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    168. Nerurkar PV, Lee YK, Motosue M, Adeli K, Nerurkar VR. Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. Br J Nutr. 2008 Oct; 100(4):751-9. PMID: 18321395.
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    169. Miller A, Adeli K. Dietary fructose and the metabolic syndrome. Curr Opin Gastroenterol. 2008 Mar; 24(2):204-9. PMID: 18301272.
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    170. Naples M, Federico LM, Xu E, Nelken J, Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis. 2008 May; 198(1):94-103. PMID: 18093597.
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    171. Kelishadi R, Hashemipour M, Mohammadifard N, Alikhassy H, Adeli K. Short- and long-term relationships of serum ghrelin with changes in body composition and the metabolic syndrome in prepubescent obese children following two different weight loss programmes. Clin Endocrinol (Oxf). 2008 Nov; 69(5):721-9. PMID: 18284632.
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    172. Nelken J, Meshkani R, Chahal N, McCrindle B, Adeli K. Detection of familial defective apoB (FDB) mutations in hypercholesterolemic children and adolescents by denaturing high performance liquid chromatography (DHPLC). Clin Biochem. 2008 Apr; 41(6):395-9. PMID: 18222178.
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    173. Engelhardt T, McCheyne AJ, Morton N, Karsli C, Luginbuehl I, Adeli K, Walsh W, Bissonnette B. Clinical adaptation of a pharmacokinetic model of Propofol plasma concentrations in children. Paediatr Anaesth. 2008 Mar; 18(3):235-9. PMID: 18179618.
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    174. Nylen K, Velazquez JL, Likhodii SS, Cortez MA, Shen L, Leshchenko Y, Adeli K, Gibson KM, Burnham WM, Snead OC. A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype. Exp Neurol. 2008 Apr; 210(2):449-57. PMID: 18199435; PMCID: PMC2362105.
    175. Kelishadi R, Gouya MM, Adeli K, Ardalan G, Gheiratmand R, Majdzadeh R, Mahmoud-Arabi MS, Delavari A, Riazi MM, Barekati H, Motaghian M, Shariatinejad K, Heshmat R. Factors associated with the metabolic syndrome in a national sample of youths: CASPIAN Study. Nutr Metab Cardiovasc Dis. 2008 Sep; 18(7):461-70. PMID: 17935959.
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    176. Kelishadi R, Badiee Z, Adeli K. Cord blood lipid profile and associated factors: baseline data of a birth cohort study. Paediatr Perinat Epidemiol. 2007 Nov; 21(6):518-24. PMID: 17937737.
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    177. McCrindle BW, McIntyre S, Kim C, Lin T, Adeli K. Are patients after Kawasaki disease at increased risk for accelerated atherosclerosis? J Pediatr. 2007 Sep; 151(3):244-8, 248.e1. PMID: 17719931.
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    178. Meshkani R, Taghikhani M, Al-Kateb H, Larijani B, Khatami S, Sidiropoulos GK, Hegele RA, Adeli K. Polymorphisms within the protein tyrosine phosphatase 1B (PTPN1) gene promoter: functional characterization and association with type 2 diabetes and related metabolic traits. Clin Chem. 2007 Sep; 53(9):1585-92. PMID: 17634210.
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    179. Sidiropoulos KG, Meshkani R, Avramoglu-Kohen R, Adeli K. Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation. Arch Biochem Biophys. 2007 Sep 15; 465(2):380-8. PMID: 17698027.
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    180. Kelishadi R, Ardalan G, Adeli K, Motaghian M, Majdzadeh R, Mahmood-Arabi MS, Delavari A, Riazi MM, Namazi R, Ramezani MA. Factor analysis of cardiovascular risk clustering in pediatric metabolic syndrome: CASPIAN study. Ann Nutr Metab. 2007; 51(3):208-15. PMID: 17587791.
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    181. Li L, Naples M, Song H, Yuan R, Ye F, Shafi S, Adeli K, Ng DS. LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E587-94. PMID: 17551001.
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    182. Rutledge AC, Adeli K. Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms. Nutr Rev. 2007 Jun; 65(6 Pt 2):S13-23. PMID: 17605309.
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    183. Meshkani R, Taghikhani M, Mosapour A, Larijani B, Khatami S, Khoshbin E, Ahmadvand D, Saeidi P, Maleki A, Yavari K, Nasoohi N, Adeli K. 1484insG polymorphism of the PTPN1 gene is associated with insulin resistance in an Iranian population. Arch Med Res. 2007 Jul; 38(5):556-62. PMID: 17560463.
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    184. Qin B, Qiu W, Avramoglu RK, Adeli K. Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes. 2007 Feb; 56(2):450-61. PMID: 17259391.
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    185. Kelishadi R, Sharifi M, Khosravi A, Adeli K. Relationship between C-reactive protein and atherosclerotic risk factors and oxidative stress markers among young persons 10-18 years old. Clin Chem. 2007 Mar; 53(3):456-64. PMID: 17259238.
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    186. Meshkani R, Taghikhani M, Larijani B, Bahrami Y, Khatami S, Khoshbin E, Ghaemi A, Sadeghi S, Mirkhani F, Molapour A, Adeli K. Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population. Clin Chem Lab Med. 2007; 45(4):477-82. PMID: 17439324.
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    187. Kelishadi R, Ardalan G, Gheiratmand R, Adeli K, Delavari A, Majdzadeh R. Paediatric metabolic syndrome and associated anthropometric indices: the CASPIAN Study. Acta Paediatr. 2006 Dec; 95(12):1625-34. PMID: 17129973.
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    188. Sidiropoulos KG, Zastepa A, Adeli K. Translational control of apolipoprotein B mRNA via insulin and the protein kinase C signaling cascades: evidence for modulation of RNA-protein interactions at the 5'UTR. Arch Biochem Biophys. 2007 Mar 01; 459(1):10-9. PMID: 17288985.
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    189. Tsai J, Qiu W, Kohen-Avramoglu R, Adeli K. MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):211-8. PMID: 17038630.
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    190. Hasspieler B, Haffner D, Stelljes M, Adeli K. Toxicological assessment of industrial solvents using human cell bioassays: assessment of short-term cytotoxicity and long-term genotoxicity potential. Toxicol Ind Health. 2006 Aug; 22(7):301-15. PMID: 17022437.
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    191. Yip PM, Chan MK, Nelken J, Lepage N, Brotea G, Adeli K. Pediatric reference intervals for lipids and apolipoproteins on the VITROS 5,1 FS Chemistry System. Clin Biochem. 2006 Oct; 39(10):978-83. PMID: 16962571.
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    192. Kelishadi R, Gheiratmand R, Ardalan G, Adeli K, Mehdi Gouya M, Mohammad Razaghi E, Majdzadeh R, Delavari A, Shariatinejad K, Motaghian M, Heshmat R, Heidarzadeh A, Barekati H, Sadat Mahmoud-Arabi M, Mehdi Riazi M. Association of anthropometric indices with cardiovascular disease risk factors among children and adolescents: CASPIAN Study. Int J Cardiol. 2007 May 02; 117(3):340-8. PMID: 16860411.
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    193. Meshkani R, Taghikhani M, Larijani B, Khatami S, Khoshbin E, Adeli K. The relationship between homeostasis model assessment and cardiovascular risk factors in Iranian subjects with normal fasting glucose and normal glucose tolerance. Clin Chim Acta. 2006 Sep; 371(1-2):169-75. PMID: 16714005.
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    194. Qiu W, Avramoglu RK, Rutledge AC, Tsai J, Adeli K. Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins. J Lipid Res. 2006 Aug; 47(8):1749-61. PMID: 16672736.
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    195. Federico LM, Naples M, Taylor D, Adeli K. Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine. Diabetes. 2006 May; 55(5):1316-26. PMID: 16644688.
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    196. Mansoub S, Chan MK, Adeli K. Gap analysis of pediatric reference intervals for risk biomarkers of cardiovascular disease and the metabolic syndrome. Clin Biochem. 2006 Jun; 39(6):569-87. PMID: 16624272.
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    197. Sarkissian T, Beyenne J, Feldman B, Adeli K, Silverman E. The complex nature of the interaction between disease activity and therapy on the lipid profile in patients with pediatric systemic lupus erythematosus. Arthritis Rheum. 2006 Apr; 54(4):1283-90. PMID: 16575849.
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    198. Avramoglu RK, Basciano H, Adeli K. Lipid and lipoprotein dysregulation in insulin resistant states. Clin Chim Acta. 2006 Jun; 368(1-2):1-19. PMID: 16480697.
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    199. Yip PM, Chan MK, Zielinski N, Adeli K. Heparin interference in whole blood sodium measurements in a pediatric setting. Clin Biochem. 2006 Apr; 39(4):391-5. PMID: 16443209.
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    200. Li RW, Douglas TD, Maiyoh GK, Adeli K, Theriault AG. Green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model. J Ethnopharmacol. 2006 Mar 08; 104(1-2):24-31. PMID: 16202550.
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    201. Sidiropoulos KG, Pontrelli L, Adeli K. Insulin-mediated suppression of apolipoprotein B mRNA translation requires the 5' UTR and is characterized by decreased binding of an insulin-sensitive 110-kDa 5' UTR RNA-binding protein. Biochemistry. 2005 Sep 20; 44(37):12572-81. PMID: 16156669.
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    202. Chong T, Naples M, Federico L, Taylor D, Smith GJ, Cheung RC, Adeli K. Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia. Atherosclerosis. 2006 Mar; 185(1):21-31. PMID: 16002078.
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    203. Mielke JG, Taghibiglou C, Liu L, Zhang Y, Jia Z, Adeli K, Wang YT. A biochemical and functional characterization of diet-induced brain insulin resistance. J Neurochem. 2005 Jun; 93(6):1568-78. PMID: 15935073.
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    204. Emadi-Konjin P, Verjee Z, Levin AV, Adeli K. Measurement of intracellular vitamin C levels in human lymphocytes by reverse phase high performance liquid chromatography (HPLC). Clin Biochem. 2005 May; 38(5):450-6. PMID: 15820776.
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    205. Guo Q, Avramoglu RK, Adeli K. Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids. Metabolism. 2005 May; 54(5):689-97. PMID: 15877301.
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    206. Nerurkar PV, Pearson L, Efird JT, Adeli K, Theriault AG, Nerurkar VR. Microsomal triglyceride transfer protein gene expression and ApoB secretion are inhibited by bitter melon in HepG2 cells. J Nutr. 2005 Apr; 135(4):702-6. PMID: 15795421.
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    207. Morand JP, Macri J, Adeli K. Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia. J Biol Chem. 2005 May 06; 280(18):17626-33. PMID: 15760893.
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    208. Wan B, Augustin R, Chan MK, Leblond J, Verjee Z, Adeli K. Analytical performance and workflow evaluation of the Roche E170 modular immunoassay analyzer in a pediatric setting. Clin Biochem. 2005 Mar; 38(3):262-71. PMID: 15708549.
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    209. Qiu W, Taghibiglou C, Avramoglu RK, Van Iderstine SC, Naples M, Ashrafpour H, Mhapsekar S, Sato R, Adeli K. Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance. Biochemistry. 2005 Mar 01; 44(8):3041-9. PMID: 15723548.
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    210. Casaschi A, Maiyoh GK, Adeli K, Theriault AG. Increased diacylglycerol acyltransferase activity is associated with triglyceride accumulation in tissues of diet-induced insulin-resistant hyperlipidemic hamsters. Metabolism. 2005 Mar; 54(3):403-9. PMID: 15736121.
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    211. Basciano H, Federico L, Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond). 2005 Feb 21; 2(1):5. PMID: 15723702.
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    212. Qiu W, Kohen-Avramoglu R, Mhapsekar S, Tsai J, Austin RC, Adeli K. Glucosamine-induced endoplasmic reticulum stress promotes ApoB100 degradation: evidence for Grp78-mediated targeting to proteasomal degradation. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):571-7. PMID: 15618547.
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    213. Avramoglu RK, Adeli K. Hepatic regulation of apolipoprotein B. Rev Endocr Metab Disord. 2004 Dec; 5(4):293-301. PMID: 15486461.
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    214. Qiu W, Avramoglu RK, Dubé N, Chong TM, Naples M, Au C, Sidiropoulos KG, Lewis GF, Cohn JS, Tremblay ML, Adeli K. Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies. Diabetes. 2004 Dec; 53(12):3057-66. PMID: 15561934.
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    215. Lewis GF, Murdoch S, Uffelman K, Naples M, Szeto L, Albers A, Adeli K, Brunzell JD. Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone. Diabetes. 2004 Nov; 53(11):2893-900. PMID: 15504970.
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    216. Lewis GF, Uffelman K, Naples M, Szeto L, Haidari M, Adeli K. Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster. Endocrinology. 2005 Jan; 146(1):247-55. PMID: 15486228.
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    217. Stefan C, Walsh W, Banka T, Adeli K, Verjee Z. Improved HPLC methodology for monitoring thiopurine metabolites in patients on thiopurine therapy. Clin Biochem. 2004 Sep; 37(9):764-71. PMID: 15329314.
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    218. Kavsak PA, Zielinski N, Li D, McNamara PJ, Adeli K. Challenges of implementing point-of-care testing (POCT) glucose meters in a pediatric acute care setting. Clin Biochem. 2004 Sep; 37(9):811-7. PMID: 15329321.
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    219. Lewis GF, Naples M, Uffelman K, Leung N, Szeto L, Adeli K. Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters. Endocrinology. 2004 Nov; 145(11):5006-12. PMID: 15271878.
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    220. Leung N, Naples M, Uffelman K, Szeto L, Adeli K, Lewis GF. Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance. Atherosclerosis. 2004 Jun; 174(2):235-41. PMID: 15136053.
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    221. Pontrelli L, Sidiropoulos KG, Adeli K. Translational control of apolipoprotein B mRNA: regulation via cis elements in the 5' and 3' untranslated regions. Biochemistry. 2004 Jun 01; 43(21):6734-44. PMID: 15157107.
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    222. Casaschi A, Maiyoh GK, Rubio BK, Li RW, Adeli K, Theriault AG. The chalcone xanthohumol inhibits triglyceride and apolipoprotein B secretion in HepG2 cells. J Nutr. 2004 Jun; 134(6):1340-6. PMID: 15173394.
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    223. Qiu W, Kohen-Avramoglu R, Rashid-Kolvear F, Au CS, Chong TM, Lewis GF, Trinh DK, Austin RC, Urade R, Adeli K. Overexpression of the endoplasmic reticulum 60 protein ER-60 downregulates apoB100 secretion by inducing its intracellular degradation via a nonproteasomal pathway: evidence for an ER-60-mediated and pCMB-sensitive intracellular degradative pathway. Biochemistry. 2004 Apr 27; 43(16):4819-31. PMID: 15096051.
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    224. Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism. 2004 Feb; 53(2):228-35. PMID: 14767876.
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    225. Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia. Clin Biochem. 2003 Sep; 36(6):413-20. PMID: 12951167.
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    226. Avramoglu RK, Qiu W, Adeli K. Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Front Biosci. 2003 Jan 01; 8:d464-76. PMID: 12456312.
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    227. Bonn V, Cheung RC, Chen B, Taghibiglou C, Van Iderstine SC, Adeli K. Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. Atherosclerosis. 2002 Jul; 163(1):59-68. PMID: 12048122.
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    228. Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K. Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction. J Biol Chem. 2002 Aug 30; 277(35):31646-55. PMID: 12070142.
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    229. Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster. J Biol Chem. 2002 Aug 09; 277(32):28795-802. PMID: 12048212.
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    230. Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism. 2002 Apr; 51(4):409-18. PMID: 11912545.
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    231. Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev. 2002 Apr; 23(2):201-29. PMID: 11943743.
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    232. Rashid S, Barrett PH, Uffelman KD, Watanabe T, Adeli K, Lewis GF. Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arterioscler Thromb Vasc Biol. 2002 Mar 01; 22(3):483-7. PMID: 11884294.
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    233. Pontrelli L, Parris W, Adeli K, Cheung RC. Atorvastatin treatment beneficially alters the lipoprotein profile and increases low-density lipoprotein particle diameter in patients with combined dyslipidemia and impaired fasting glucose/type 2 diabetes. Metabolism. 2002 Mar; 51(3):334-42. PMID: 11887170.
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    234. Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K. Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Biochem Pharmacol. 2002 Feb 01; 63(3):349-60. PMID: 11853686.
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    235. Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance. J Biol Chem. 2002 Jan 04; 277(1):793-803. PMID: 11598116.
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    236. Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends Cardiovasc Med. 2001 Jul; 11(5):170-6. PMID: 11597827.
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    237. Rashid S, Uffelman KD, Barrett PH, Vicini P, Adeli K, Lewis GF. Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester clearance in rabbits. J Lipid Res. 2001 Feb; 42(2):265-71. PMID: 11181757.
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    238. Theriault A, Wang Q, Van Iderstine SC, Chen B, Franke AA, Adeli K. Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid. J Lipid Res. 2000 Dec; 41(12):1969-79. PMID: 11108730.
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    239. Macri J, Kazemian P, Kulinski A, Rudy D, Aiton A, Thibert RJ, Adeli K. Translocational status of ApoB in the presence of an inhibitor of microsomal triglyceride transfer protein. Biochem Biophys Res Commun. 2000 Oct 05; 276(3):1035-47. PMID: 11027587.
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    240. Taghibiglou C, Rudy D, Van Iderstine SC, Aiton A, Cavallo D, Cheung R, Adeli K. Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes. J Lipid Res. 2000 Apr; 41(4):499-513. PMID: 10744770.
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    241. Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J Biol Chem. 2000 Mar 24; 275(12):8416-25. PMID: 10722675.
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    242. Cavallo D, Rudy D, Mohammadi A, Macri J, Adeli K. Studies on degradative mechanisms mediating post-translational fragmentation of apolipoprotein B and the generation of the 70-kDa fragment. J Biol Chem. 1999 Aug 13; 274(33):23135-43. PMID: 10438483.
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    243. Theriault A, Chao JT, Wang Q, Gapor A, Adeli K. Tocotrienol: a review of its therapeutic potential. Clin Biochem. 1999 Jul; 32(5):309-19. PMID: 10480444.
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    244. Theriault A, Wang Q, Gapor A, Adeli K. Effects of gamma-tocotrienol on ApoB synthesis, degradation, and secretion in HepG2 cells. Arterioscler Thromb Vasc Biol. 1999 Mar; 19(3):704-12. PMID: 10073977.
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    245. Cavallo D, McLeod RS, Rudy D, Aiton A, Yao Z, Adeli K. Intracellular translocation and stability of apolipoprotein B are inversely proportional to the length of the nascent polypeptide. J Biol Chem. 1998 Dec 11; 273(50):33397-405. PMID: 9837916.
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    246. Wang Q, Theriault A, Gapor A, Adeli K. Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. Biochem Biophys Res Commun. 1998 May 29; 246(3):640-3. PMID: 9618265.
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    247. Mohammadi A, Macri J, Newton R, Romain T, Dulay D, Adeli K. Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells. Arterioscler Thromb Vasc Biol. 1998 May; 18(5):783-93. PMID: 9598838.
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    248. Tran K, Borén J, Macri J, Wang Y, McLeod R, Avramoglu RK, Adeli K, Yao Z. Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B. J Biol Chem. 1998 Mar 27; 273(13):7244-51. PMID: 9516417.
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    249. Macri J, Adeli K. Conformational changes in apolipoprotein B modulate intracellular assembly and degradation of ApoB-containing lipoprotein particles in HepG2 cells. Arterioscler Thromb Vasc Biol. 1997 Nov; 17(11):2982-94. PMID: 9409285.
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    250. Hasspieler BM, Haffner GD, Adeli K. Roles of DT diaphorase in the genotoxicity of nitroaromatic compounds in human and fish cell lines. J Toxicol Environ Health. 1997 Oct 10; 52(2):137-48. PMID: 9310146.
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    251. Adeli K, Macri J, Mohammadi A, Kito M, Urade R, Cavallo D. Apolipoprotein B is intracellularly associated with an ER-60 protease homologue in HepG2 cells. J Biol Chem. 1997 Sep 05; 272(36):22489-94. PMID: 9278400.
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    252. Macri J, Adeli K. Studies on intracellular translocation of apolipoprotein B in a permeabilized HepG2 system. J Biol Chem. 1997 Mar 14; 272(11):7328-37. PMID: 9054431.
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    253. Adeli K, Wettesten M, Asp L, Mohammadi A, Macri J, Olofsson SO. Intracellular assembly and degradation of apolipoprotein B-100-containing lipoproteins in digitonin-permeabilized HEP G2 cells. J Biol Chem. 1997 Feb 21; 272(8):5031-9. PMID: 9030566.
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    254. Mohammadi A, Theriault A, Adeli K. In vitro translation and translocation of apolipoprotein B in a cell-free system from HepG2 cells. Biochem Biophys Res Commun. 1996 Nov 21; 228(3):852-8. PMID: 8941365.
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    255. Hasspieler BM, Haffner GD, Adeli K. In vitro toxicological methods for environmental health testing. Rev Environ Health. 1996 Oct-Dec; 11(4):213-27. PMID: 9085437.
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    256. Mao GD, Adeli K, Eisenbrey AB, Artiss JD. Clinical laboratory investigation of the Sanofi ACCESS CK-MB procedure and comparison to electrophoresis and Abbott IMx. Am J Clin Pathol. 1996 Jul; 106(1):112-7. PMID: 8701919.
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    257. Hasspieler BM, Haffner GD, Adeli K. Influence of DT diaphorase on quinone-mediated genotoxicity in human and fish cell lines. Mutat Res. 1996 May 17; 360(1):43-9. PMID: 8657209.
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    258. Hasspieler BM, Ali FN, Alipour M, Haffner GD, Adeli K. Human bioassays to assess environmental genotoxicity: development of a DNA break bioassay in HepG2 cells. Clin Biochem. 1995 Apr; 28(2):113-6. PMID: 7628068.
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    259. Ogbonna G, Caines PS, Catomeris P, Thibert RJ, Adeli K. A competitive chemiluminescent immunoassay for the sensitive measurement of apolipoprotein B100. Clin Biochem. 1995 Apr; 28(2):117-22. PMID: 7628069.
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    260. Adeli K, Mohammadi A, Macri J. Regulation of apolipoprotein B biogenesis in human hepatocytes: posttranscriptional control mechanisms that determine the hepatic production of apolipoprotein B-containing lipoproteins. Clin Biochem. 1995 Apr; 28(2):123-30. PMID: 7628070.
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    261. Sallach SM, Adeli K. Intracellular degradation of apolipoprotein B generates an N-terminal 70 kDa fragment in the endoplasmic reticulum. Biochim Biophys Acta. 1995 Feb 16; 1265(1):29-32. PMID: 7857981.
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    262. Naji-Ali F, Hasspieler BM, Haffner D, Adeli K. Human bioassays to assess environmental genotoxicity: development of a DNA repair assay in HepG2 cells. Clin Biochem. 1994 Dec; 27(6):441-8. PMID: 7697889.
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    263. Adeli K. Regulated intracellular degradation of apolipoprotein B in semipermeable HepG2 cells. J Biol Chem. 1994 Mar 25; 269(12):9166-75. PMID: 8132654.
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    264. Dufresne M, Jane D, Theriault A, Adeli K. Expression of cathepsin B and aryl hydrocarbon hydroxylase activities, and of apolipoprotein B in human hepatoma cells maintained long-term in a serum-free medium. In Vitro Cell Dev Biol Anim. 1993 Nov; 29A(11):873-8. PMID: 8167904.
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    265. Galvan B, Macri J, Adeli K. An amplified enzyme-linked immunosorbent assay for rapid and sensitive determination of apolipoprotein AI in plasma and tissue culture media. Ann Clin Biochem. 1993 Jul; 30 ( Pt 4):404-6. PMID: 8379654.
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    266. Macri J, Adeli K. Development of an amplified enzyme-linked immunosorbent assay for sensitive measurement of apolipoprotein B in plasma and tissue culture media. Eur J Clin Chem Clin Biochem. 1993 Jul; 31(7):441-6. PMID: 8399784.
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    267. Ogbonna G, Theriault A, Adeli K. Hormonal regulation of human apolipoprotein E gene expression in HepG2 cells. Int J Biochem. 1993 May; 25(5):635-40. PMID: 8349006.
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    268. Adeli K, Theriault A. Insulin modulation of human apolipoprotein B mRNA translation: studies in an in vitro cell-free system from HepG2 cells. Biochem Cell Biol. 1992 Dec; 70(12):1301-12. PMID: 1338569.
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    269. Ogbonna G, Cheung RM, Wong G, Adeli K. Apolipoprotein B gene polymorphism and plasma lipids and lipoproteins in a Canadian Caucasian population. Clin Biochem. 1992 Dec; 25(6):471-8. PMID: 1477972.
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    270. Theriault A, Cheung R, Adeli K. Expression of apolipoprotein B in vitro in cell-free lysates of HepG2 cells: evidence that insulin modulates ApoB synthesis at the translational level. Clin Biochem. 1992 Oct; 25(5):321-3. PMID: 1337019.
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    271. Theriault A, Ogbonna G, Adeli K. Thyroid hormone modulates apolipoprotein B gene expression in HepG2 cells. Biochem Biophys Res Commun. 1992 Jul 31; 186(2):617-23. PMID: 1323286.
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    272. Hasnain S, Adeli K, Storer AC. Purification and characterization of an extracellular thiol-containing serine proteinase from Thermomyces lanuginosus. Biochem Cell Biol. 1992 Feb; 70(2):117-22. PMID: 1510823.
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    273. Adeli K, Sinkevitch C. Secretion of apolipoprotein B in serum-free cultures of human hepatoma cell line, HepG2. FEBS Lett. 1990 Apr 24; 263(2):345-8. PMID: 2185956.
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    274. Adeli K, Ogbonna G. Rapid purification of human DNA from whole blood for potential application in clinical chemistry laboratories. Clin Chem. 1990 Feb; 36(2):261-4. PMID: 1967986.
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    275. Robert LS, Adeli K, Altosaar I. Homology among 3S and 7S Globulins from Cereals and Pea. Plant Physiol. 1985 Aug; 78(4):812-6. PMID: 16664331.
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    276. Adeli K, Allan-Wojtas P, Altosaar I. Intracellular transport and posttranslational cleavage of oat globulin precursors. Plant Physiol. 1984 Sep; 76(1):16-20. PMID: 16663789.
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    277. Adeli K, Altosaar I. Characterization of oat vicilin-like polypeptides. Plant Physiol. 1984 May; 75(1):225-7. PMID: 16663577.
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    278. Adeli K, Altosaar I. Role of endoplasmic reticulum in biosynthesis of oat globulin precursors. Plant Physiol. 1983 Dec; 73(4):949-55. PMID: 16663349.
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    279. Garson K, Matlashewski GJ, Adeli K, Robert LS, Altosaar I. Isolation of intact polysomes from mechanically dehulled developing grain. Anal Biochem. 1983 Oct 15; 134(2):512-6. PMID: 6650835.
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