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Connection

Khosrow Adeli to Liver

This is a "connection" page, showing publications Khosrow Adeli has written about Liver.

 
Connection Strength
 
 
 
9.449
 
  1. Zhang J, Jazii FR, Haghighi MM, Alvares D, Liu L, Khosraviani N, Adeli K. miR-130b is a potent stimulator of hepatic very-low-density lipoprotein assembly and secretion via marked induction of microsomal triglyceride transfer protein. Am J Physiol Endocrinol Metab. 2020 02 01; 318(2):E262-E275.
    View in: PubMed
    Score: 0.705
  2. Taher J, Baker C, Alvares D, Ijaz L, Hussain M, Adeli K. GLP-2 Dysregulates Hepatic Lipoprotein Metabolism, Inducing Fatty Liver and VLDL Overproduction in Male Hamsters and Mice. Endocrinology. 2018 09 01; 159(9):3340-3350.
    View in: PubMed
    Score: 0.645
  3. Zhang J, Zamani M, Thiele C, Taher J, Amir Alipour M, Yao Z, Adeli K. AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion. Arterioscler Thromb Vasc Biol. 2017 04; 37(4):633-642.
    View in: PubMed
    Score: 0.579
  4. Taher J, Farr S, Adeli K. Central nervous system regulation of hepatic lipid and lipoprotein metabolism. Curr Opin Lipidol. 2017 02; 28(1):32-38.
    View in: PubMed
    Score: 0.578
  5. Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2104-12.
    View in: PubMed
    Score: 0.421
  6. Su Q, Tsai J, Xu E, Qiu W, Bereczki E, Santha M, Adeli K. Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology. 2009 Jul; 50(1):77-84.
    View in: PubMed
    Score: 0.342
  7. Meshkani R, Adeli K. Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clin Biochem. 2009 Sep; 42(13-14):1331-46.
    View in: PubMed
    Score: 0.340
  8. Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1287-98.
    View in: PubMed
    Score: 0.336
  9. Qin B, Anderson RA, Adeli K. Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1120-9.
    View in: PubMed
    Score: 0.313
  10. Naples M, Federico LM, Xu E, Nelken J, Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis. 2008 May; 198(1):94-103.
    View in: PubMed
    Score: 0.311
  11. Chong T, Naples M, Federico L, Taylor D, Smith GJ, Cheung RC, Adeli K. Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia. Atherosclerosis. 2006 Mar; 185(1):21-31.
    View in: PubMed
    Score: 0.259
  12. Avramoglu RK, Adeli K. Hepatic regulation of apolipoprotein B. Rev Endocr Metab Disord. 2004 Dec; 5(4):293-301.
    View in: PubMed
    Score: 0.249
  13. Qiu W, Avramoglu RK, Dubé N, Chong TM, Naples M, Au C, Sidiropoulos KG, Lewis GF, Cohn JS, Tremblay ML, Adeli K. Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies. Diabetes. 2004 Dec; 53(12):3057-66.
    View in: PubMed
    Score: 0.249
  14. Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism. 2004 Feb; 53(2):228-35.
    View in: PubMed
    Score: 0.235
  15. Avramoglu RK, Qiu W, Adeli K. Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Front Biosci. 2003 Jan 01; 8:d464-76.
    View in: PubMed
    Score: 0.218
  16. Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism. 2002 Apr; 51(4):409-18.
    View in: PubMed
    Score: 0.207
  17. Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance. J Biol Chem. 2002 Jan 04; 277(1):793-803.
    View in: PubMed
    Score: 0.200
  18. Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends Cardiovasc Med. 2001 Jul; 11(5):170-6.
    View in: PubMed
    Score: 0.196
  19. Theriault A, Wang Q, Van Iderstine SC, Chen B, Franke AA, Adeli K. Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid. J Lipid Res. 2000 Dec; 41(12):1969-79.
    View in: PubMed
    Score: 0.188
  20. Taghibiglou C, Rudy D, Van Iderstine SC, Aiton A, Cavallo D, Cheung R, Adeli K. Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes. J Lipid Res. 2000 Apr; 41(4):499-513.
    View in: PubMed
    Score: 0.180
  21. Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J Biol Chem. 2000 Mar 24; 275(12):8416-25.
    View in: PubMed
    Score: 0.180
  22. Theriault A, Wang Q, Gapor A, Adeli K. Effects of gamma-tocotrienol on ApoB synthesis, degradation, and secretion in HepG2 cells. Arterioscler Thromb Vasc Biol. 1999 Mar; 19(3):704-12.
    View in: PubMed
    Score: 0.167
  23. Alvares D, Hoffman S, Stankovic B, Adeli K. Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 03; 1864(3):326-334.
    View in: PubMed
    Score: 0.165
  24. Wang Q, Theriault A, Gapor A, Adeli K. Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. Biochem Biophys Res Commun. 1998 May 29; 246(3):640-3.
    View in: PubMed
    Score: 0.158
  25. Macri J, Adeli K. Conformational changes in apolipoprotein B modulate intracellular assembly and degradation of ApoB-containing lipoprotein particles in HepG2 cells. Arterioscler Thromb Vasc Biol. 1997 Nov; 17(11):2982-94.
    View in: PubMed
    Score: 0.152
  26. Khound R, Taher J, Baker C, Adeli K, Su Q. GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2252-2259.
    View in: PubMed
    Score: 0.152
  27. Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochim Biophys Acta. 2016 Jul; 1861(7):594-605.
    View in: PubMed
    Score: 0.137
  28. Adeli K, Mohammadi A, Macri J. Regulation of apolipoprotein B biogenesis in human hepatocytes: posttranscriptional control mechanisms that determine the hepatic production of apolipoprotein B-containing lipoproteins. Clin Biochem. 1995 Apr; 28(2):123-30.
    View in: PubMed
    Score: 0.127
  29. Farr S, Taher J, Adeli K. Glucagon-like peptide-1 as a key regulator of lipid and lipoprotein metabolism in fasting and postprandial states. Cardiovasc Hematol Disord Drug Targets. 2014; 14(2):126-36.
    View in: PubMed
    Score: 0.117
  30. Ogbonna G, Theriault A, Adeli K. Hormonal regulation of human apolipoprotein E gene expression in HepG2 cells. Int J Biochem. 1993 May; 25(5):635-40.
    View in: PubMed
    Score: 0.111
  31. Dekker MJ, Baker C, Naples M, Samsoondar J, Zhang R, Qiu W, Sacco J, Adeli K. Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis. 2013 May; 228(1):98-109.
    View in: PubMed
    Score: 0.110
  32. Hager L, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS. Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice. J Biol Chem. 2012 Jun 08; 287(24):20755-68.
    View in: PubMed
    Score: 0.104
  33. Yue JT, Mighiu PI, Naples M, Adeli K, Lam TK. Glycine normalizes hepatic triglyceride-rich VLDL secretion by triggering the CNS in high-fat fed rats. Circ Res. 2012 May 11; 110(10):1345-54.
    View in: PubMed
    Score: 0.103
  34. Xiao C, Hsieh J, Adeli K, Lewis GF. Gut-liver interaction in triglyceride-rich lipoprotein metabolism. Am J Physiol Endocrinol Metab. 2011 Sep; 301(3):E429-46.
    View in: PubMed
    Score: 0.098
  35. Xi L, Xiao C, Bandsma RH, Naples M, Adeli K, Lewis GF. C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases. Hepatology. 2011 Jan; 53(1):127-35.
    View in: PubMed
    Score: 0.093
  36. Adeli K, Sinkevitch C. Secretion of apolipoprotein B in serum-free cultures of human hepatoma cell line, HepG2. FEBS Lett. 1990 Apr 24; 263(2):345-8.
    View in: PubMed
    Score: 0.090
  37. Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K. Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. Hepatology. 2008 Dec; 48(6):1799-809.
    View in: PubMed
    Score: 0.082
  38. Adeli K, Lewis GF. Intestinal lipoprotein overproduction in insulin-resistant states. Curr Opin Lipidol. 2008 Jun; 19(3):221-8.
    View in: PubMed
    Score: 0.079
  39. Nerurkar PV, Lee YK, Motosue M, Adeli K, Nerurkar VR. Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. Br J Nutr. 2008 Oct; 100(4):751-9.
    View in: PubMed
    Score: 0.078
  40. Li L, Naples M, Song H, Yuan R, Ye F, Shafi S, Adeli K, Ng DS. LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E587-94.
    View in: PubMed
    Score: 0.074
  41. Morand JP, Macri J, Adeli K. Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia. J Biol Chem. 2005 May 06; 280(18):17626-33.
    View in: PubMed
    Score: 0.063
  42. Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia. Clin Biochem. 2003 Sep; 36(6):413-20.
    View in: PubMed
    Score: 0.057
  43. Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster. J Biol Chem. 2002 Aug 09; 277(32):28795-802.
    View in: PubMed
    Score: 0.052
  44. Naji-Ali F, Hasspieler BM, Haffner D, Adeli K. Human bioassays to assess environmental genotoxicity: development of a DNA repair assay in HepG2 cells. Clin Biochem. 1994 Dec; 27(6):441-8.
    View in: PubMed
    Score: 0.031
  45. Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan; 54(1):134-51.
    View in: PubMed
    Score: 0.027
  46. Dong B, Wu M, Li H, Kraemer FB, Adeli K, Seidah NG, Park SW, Liu J. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. J Lipid Res. 2010 Jun; 51(6):1486-95.
    View in: PubMed
    Score: 0.022
  47. Casaschi A, Maiyoh GK, Adeli K, Theriault AG. Increased diacylglycerol acyltransferase activity is associated with triglyceride accumulation in tissues of diet-induced insulin-resistant hyperlipidemic hamsters. Metabolism. 2005 Mar; 54(3):403-9.
    View in: PubMed
    Score: 0.016
  48. Lewis GF, Murdoch S, Uffelman K, Naples M, Szeto L, Albers A, Adeli K, Brunzell JD. Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone. Diabetes. 2004 Nov; 53(11):2893-900.
    View in: PubMed
    Score: 0.015
  49. Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev. 2002 Apr; 23(2):201-29.
    View in: PubMed
    Score: 0.013
  50. Rashid S, Barrett PH, Uffelman KD, Watanabe T, Adeli K, Lewis GF. Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arterioscler Thromb Vasc Biol. 2002 Mar 01; 22(3):483-7.
    View in: PubMed
    Score: 0.013
  51. Rashid S, Uffelman KD, Barrett PH, Vicini P, Adeli K, Lewis GF. Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester clearance in rabbits. J Lipid Res. 2001 Feb; 42(2):265-71.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.