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Connection

Khosrow Adeli to Insulin

This is a "connection" page, showing publications Khosrow Adeli has written about Insulin.

 
Connection Strength
 
 
 
5.548
 
  1. Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2104-12.
    View in: PubMed
    Score: 0.458
  2. Karimian Pour N, Adeli K. Insulin silences apolipoprotein B mRNA translation by inducing intracellular traffic into cytoplasmic RNA granules. Biochemistry. 2011 Aug 16; 50(32):6942-50.
    View in: PubMed
    Score: 0.428
  3. Basciano H, Miller A, Baker C, Naples M, Adeli K. LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. Am J Physiol Gastrointest Liver Physiol. 2009 Aug; 297(2):G323-32.
    View in: PubMed
    Score: 0.370
  4. Hsieh J, Hayashi AA, Webb J, Adeli K. Postprandial dyslipidemia in insulin resistance: mechanisms and role of intestinal insulin sensitivity. Atheroscler Suppl. 2008 Sep; 9(2):7-13.
    View in: PubMed
    Score: 0.348
  5. Sidiropoulos KG, Meshkani R, Avramoglu-Kohen R, Adeli K. Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation. Arch Biochem Biophys. 2007 Sep 15; 465(2):380-8.
    View in: PubMed
    Score: 0.324
  6. Sidiropoulos KG, Zastepa A, Adeli K. Translational control of apolipoprotein B mRNA via insulin and the protein kinase C signaling cascades: evidence for modulation of RNA-protein interactions at the 5'UTR. Arch Biochem Biophys. 2007 Mar 01; 459(1):10-9.
    View in: PubMed
    Score: 0.310
  7. Federico LM, Naples M, Taylor D, Adeli K. Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine. Diabetes. 2006 May; 55(5):1316-26.
    View in: PubMed
    Score: 0.298
  8. Sidiropoulos KG, Pontrelli L, Adeli K. Insulin-mediated suppression of apolipoprotein B mRNA translation requires the 5' UTR and is characterized by decreased binding of an insulin-sensitive 110-kDa 5' UTR RNA-binding protein. Biochemistry. 2005 Sep 20; 44(37):12572-81.
    View in: PubMed
    Score: 0.286
  9. Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism. 2004 Feb; 53(2):228-35.
    View in: PubMed
    Score: 0.255
  10. Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance. J Biol Chem. 2002 Jan 04; 277(1):793-803.
    View in: PubMed
    Score: 0.218
  11. Farr S, Stankovic B, Hoffman S, Masoudpoor H, Baker C, Taher J, Dean AE, Anakk S, Adeli K. Bile acid treatment and FXR agonism lower postprandial lipemia in mice. Am J Physiol Gastrointest Liver Physiol. 2020 04 01; 318(4):G682-G693.
    View in: PubMed
    Score: 0.193
  12. Persaud N, Ziai H, Lebovic G, Maguire JL, Khovratovich M, Simpson JAR, Adeli K, Hamilton J, McCrindle BW, Parkin PC, Birken CS. Parent reported nutritional risk and laboratory indices of cardiometabolic risk and in preschool-aged children. J Pediatr Endocrinol Metab. 2017 Aug 28; 30(8):839-846.
    View in: PubMed
    Score: 0.164
  13. Hsieh J, Trajcevski KE, Farr SL, Baker CL, Lake EJ, Taher J, Iqbal J, Hussain MM, Adeli K. Glucagon-Like Peptide 2 (GLP-2) Stimulates Postprandial Chylomicron Production and Postabsorptive Release of Intestinal Triglyceride Storage Pools via Induction of Nitric Oxide Signaling in Male Hamsters and Mice. Endocrinology. 2015 Oct; 156(10):3538-47.
    View in: PubMed
    Score: 0.141
  14. Ogbonna G, Theriault A, Adeli K. Hormonal regulation of human apolipoprotein E gene expression in HepG2 cells. Int J Biochem. 1993 May; 25(5):635-40.
    View in: PubMed
    Score: 0.121
  15. Adeli K, Theriault A. Insulin modulation of human apolipoprotein B mRNA translation: studies in an in vitro cell-free system from HepG2 cells. Biochem Cell Biol. 1992 Dec; 70(12):1301-12.
    View in: PubMed
    Score: 0.118
  16. Theriault A, Cheung R, Adeli K. Expression of apolipoprotein B in vitro in cell-free lysates of HepG2 cells: evidence that insulin modulates ApoB synthesis at the translational level. Clin Biochem. 1992 Oct; 25(5):321-3.
    View in: PubMed
    Score: 0.116
  17. Adeli K. Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules. Am J Physiol Endocrinol Metab. 2011 Dec; 301(6):E1051-64.
    View in: PubMed
    Score: 0.109
  18. Hayashi AA, Webb J, Choi J, Baker C, Lino M, Trigatti B, Trajcevski KE, Hawke TJ, Adeli K. Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G326-37.
    View in: PubMed
    Score: 0.106
  19. Xi L, Xiao C, Bandsma RH, Naples M, Adeli K, Lewis GF. C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases. Hepatology. 2011 Jan; 53(1):127-35.
    View in: PubMed
    Score: 0.102
  20. Bakhtiyari S, Meshkani R, Taghikhani M, Larijani B, Adeli K. Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells. Lipids. 2010 Mar; 45(3):237-44.
    View in: PubMed
    Score: 0.097
  21. Ragheb R, Shanab GM, Medhat AM, Seoudi DM, Adeli K, Fantus IG. Free fatty acid-induced muscle insulin resistance and glucose uptake dysfunction: evidence for PKC activation and oxidative stress-activated signaling pathways. Biochem Biophys Res Commun. 2009 Nov 13; 389(2):211-6.
    View in: PubMed
    Score: 0.094
  22. Sirek AS, Liu L, Naples M, Adeli K, Ng DS, Jin T. Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1. Endocrinology. 2009 Aug; 150(8):3483-92.
    View in: PubMed
    Score: 0.091
  23. Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K. Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. Hepatology. 2008 Dec; 48(6):1799-809.
    View in: PubMed
    Score: 0.089
  24. Qin B, Anderson RA, Adeli K. Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1120-9.
    View in: PubMed
    Score: 0.085
  25. Naples M, Federico LM, Xu E, Nelken J, Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis. 2008 May; 198(1):94-103.
    View in: PubMed
    Score: 0.085
  26. Kelishadi R, Hashemipour M, Mohammadifard N, Alikhassy H, Adeli K. Short- and long-term relationships of serum ghrelin with changes in body composition and the metabolic syndrome in prepubescent obese children following two different weight loss programmes. Clin Endocrinol (Oxf). 2008 Nov; 69(5):721-9.
    View in: PubMed
    Score: 0.084
  27. Mielke JG, Taghibiglou C, Liu L, Zhang Y, Jia Z, Adeli K, Wang YT. A biochemical and functional characterization of diet-induced brain insulin resistance. J Neurochem. 2005 Jun; 93(6):1568-78.
    View in: PubMed
    Score: 0.070
  28. Lewis GF, Naples M, Uffelman K, Leung N, Szeto L, Adeli K. Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters. Endocrinology. 2004 Nov; 145(11):5006-12.
    View in: PubMed
    Score: 0.066
  29. Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia. Clin Biochem. 2003 Sep; 36(6):413-20.
    View in: PubMed
    Score: 0.062
  30. Khound R, Taher J, Baker C, Adeli K, Su Q. GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2252-2259.
    View in: PubMed
    Score: 0.041
  31. Gorgani-Firuzjaee S, Khatami S, Adeli K, Meshkani R. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):1028-1033.
    View in: PubMed
    Score: 0.035
  32. Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013 Apr 05; 12:58.
    View in: PubMed
    Score: 0.030
  33. Yue JT, Mighiu PI, Naples M, Adeli K, Lam TK. Glycine normalizes hepatic triglyceride-rich VLDL secretion by triggering the CNS in high-fat fed rats. Circ Res. 2012 May 11; 110(10):1345-54.
    View in: PubMed
    Score: 0.028
  34. O'Gorman CS, Simoneau-Roy J, Pencharz Mb P, Adeli K, Hamilton J. Delayed ghrelin suppression following oral glucose tolerance test in children and adolescents with hypothalamic injury secondary to craniopharyngioma compared with obese controls. Int J Pediatr Obes. 2011 Aug; 6(3-4):285-8.
    View in: PubMed
    Score: 0.025
  35. Adeli K, Sinkevitch C. Secretion of apolipoprotein B in serum-free cultures of human hepatoma cell line, HepG2. FEBS Lett. 1990 Apr 24; 263(2):345-8.
    View in: PubMed
    Score: 0.025
  36. Simoneau-Roy J, O'Gorman C, Pencharz P, Adeli K, Daneman D, Hamilton J. Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma. Clin Endocrinol (Oxf). 2010 Mar; 72(3):364-70.
    View in: PubMed
    Score: 0.023
  37. Li L, Naples M, Song H, Yuan R, Ye F, Shafi S, Adeli K, Ng DS. LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E587-94.
    View in: PubMed
    Score: 0.020
  38. Casaschi A, Maiyoh GK, Adeli K, Theriault AG. Increased diacylglycerol acyltransferase activity is associated with triglyceride accumulation in tissues of diet-induced insulin-resistant hyperlipidemic hamsters. Metabolism. 2005 Mar; 54(3):403-9.
    View in: PubMed
    Score: 0.017
  39. Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster. J Biol Chem. 2002 Aug 09; 277(32):28795-802.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.