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Mark Henkelman

TitleSenior Scientist Emeritus
InstitutionThe Hospital for Sick Children
DepartmentTranslational Medicine
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Winocur G, Berman H, Nguyen M, Binns MA, Henkelman M, van Eede M, Piquette-Miller M, Sekeres MJ, Wojtowicz JM, Yu J, Zhang H, Tannock IF. Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer. Neuroscience. 2018 01 15; 369:51-65. PMID: 29113931.
      View in: PubMed
    2. Scholz J, LaLiberté C, van Eede M, Lerch JP, Henkelman M. Variability of brain anatomy for three common mouse strains. Neuroimage. 2016 Nov 15; 142:656-662. PMID: 27046115.
      View in: PubMed
    3. Grandjean J, Derungs R, Kulic L, Welt T, Henkelman M, Nitsch RM, Rudin M. Complex interplay between brain function and structure during cerebral amyloidosis in APP transgenic mouse strains revealed by multi-parametric MRI comparison. Neuroimage. 2016 07 01; 134:1-11. PMID: 27033685.
      View in: PubMed
    4. Wood ML, Griswold MA, Henkelman M, Hennig J. Inflection Points in Magnetic Resonance Imaging Technology-35 Years of Collaborative Research and Development. Invest Radiol. 2015 Sep; 50(9):645-56. PMID: 25985463.
      View in: PubMed
    5. Ellegood J, Nakai N, Nakatani J, Henkelman M, Takumi T, Lerch J. Neuroanatomical Phenotypes Are Consistent With Autism-Like Behavioral Phenotypes in the 15q11-13 Duplication Mouse Model. Autism Res. 2015 Oct; 8(5):545-55. PMID: 25755142.
      View in: PubMed
    6. Sussman D, Germann J, Henkelman M. Gestational ketogenic diet programs brain structure and susceptibility to depression & anxiety in the adult mouse offspring. Brain Behav. 2015 Feb; 5(2):e00300. PMID: 25642385.
      View in: PubMed
    7. Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, Zhengqui Z, Miller MA, Lerch JP, Henkelman M, Shamloo M, Malenka RC, Crawley JN, Dolmetsch RE. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep. 2014 May 22; 7(4):1077-1092. PMID: 24794428.
      View in: PubMed
    8. Sussman D, Ellegood J, Henkelman M. A gestational ketogenic diet alters maternal metabolic status as well as offspring physiological growth and brain structure in the neonatal mouse. BMC Pregnancy Childbirth. 2013 Oct 29; 13:198. PMID: 24168053.
      View in: PubMed
    9. Wu J, Zhou YQ, Zou Y, Henkelman M. Evaluation of bi-ventricular coronary flow patterns using high-frequency ultrasound in mice with transverse aortic constriction. Ultrasound Med Biol. 2013 Nov; 39(11):2053-65. PMID: 23932279.
      View in: PubMed
    10. Kelsey L, Flenniken AM, Qu D, Funnell AP, Pearson R, Zhou YQ, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, Scott IC, McKerlie C, Henkelman M, Backx P, Simpson J, Osborne L, Rossant J, Crossley M, Bruneau B, Adamson SL. ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. PLoS Genet. 2013; 9(7):e1003612. PMID: 23874215.
      View in: PubMed
    11. Sussman D, van Eede M, Wong MD, Adamson SL, Henkelman M. Effects of a ketogenic diet during pregnancy on embryonic growth in the mouse. BMC Pregnancy Childbirth. 2013 May 08; 13:109. PMID: 23656724.
      View in: PubMed
    12. Winocur G, Henkelman M, Wojtowicz JM, Zhang H, Binns MA, Tannock IF. The effects of chemotherapy on cognitive function in a mouse model: a prospective study. Clin Cancer Res. 2012 Jun 01; 18(11):3112-21. PMID: 22467680.
      View in: PubMed
    13. Jerkic M, Kabir MG, Davies A, Yu LX, McIntyre BA, Husain NW, Enomoto M, Sotov V, Husain M, Henkelman M, Belik J, Letarte M. Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res. 2011 Dec 01; 92(3):375-84. PMID: 21859819.
      View in: PubMed
    14. Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A. Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions. J Neurosci. 2011 Aug 10; 31(32):11547-52. PMID: 21832185.
      View in: PubMed
    15. Jeansson M, Gawlik A, Anderson G, Li C, Kerjaschki D, Henkelman M, Quaggin SE. Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest. 2011 Jun; 121(6):2278-89. PMID: 21606590.
      View in: PubMed
    16. Huang W, Zhou Z, Asrar S, Henkelman M, Xie W, Jia Z. p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties. Mol Cell Biol. 2011 Feb; 31(3):388-403. PMID: 21115725.
      View in: PubMed
    17. Toporsian M, Jerkic M, Zhou YQ, Kabir MG, Yu LX, McIntyre BA, Davis A, Wang YJ, Stewart DJ, Belik J, Husain M, Henkelman M, Letarte M. Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia. Arterioscler Thromb Vasc Biol. 2010 Mar; 30(3):509-17. PMID: 20042709.
      View in: PubMed
    18. Kaidanovich-Beilin O, Lipina TV, Takao K, van Eede M, Hattori S, Laliberté C, Khan M, Okamoto K, Chambers JW, Fletcher PJ, MacAulay K, Doble BW, Henkelman M, Miyakawa T, Roder J, Woodgett JR. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Mol Brain. 2009 Nov 19; 2:35. PMID: 19925672.
      View in: PubMed
    19. Lu H, Fedak PW, Dai X, Du C, Zhou YQ, Henkelman M, Mongroo PS, Lau A, Yamabi H, Hinek A, Husain M, Hannigan G, Coles JG. Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation. 2006 Nov 21; 114(21):2271-9. PMID: 17088456.
      View in: PubMed
    20. van Furth WR, Laughlin S, Taylor MD, Salhia B, Mainprize T, Henkelman M, Cusimano MD, Ackerley C, Rutka JT. Imaging of murine brain tumors using a 1.5 Tesla clinical MRI system. Can J Neurol Sci. 2003 Nov; 30(4):326-32. PMID: 14672264.
      View in: PubMed
    21. Karshafian R, Burns PN, Henkelman MR. Transit time kinetics in ordered and disordered vascular trees. Phys Med Biol. 2003 Oct 07; 48(19):3225-37. PMID: 14579862.
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    22. Henkelman M, Kucharczyk W. Optimization of gradient-echo MR for calcium detection. AJNR Am J Neuroradiol. 1994 Mar; 15(3):465-72. PMID: 8197942.
      View in: PubMed
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