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Brian Kavanagh

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentCritical Care Medicine
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Goligher EC, Brochard LJ, Reid WD, Fan E, Saarela O, Slutsky AS, Kavanagh BP, Rubenfeld GD, Ferguson ND. Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure. Lancet Respir Med. 2018 Nov 16. PMID: 30455078.
      View in: PubMed
    2. Tamura T, Otulakowski G, Kavanagh BP. Could Nanotechnology Make Vitamin E Therapeutically Effective? Am J Physiol Lung Cell Mol Physiol. 2018 Nov 08. PMID: 30407864.
      View in: PubMed
    3. Katira BH, Kuebler WM, Connelly KA, Kavanagh BP. Reply to: High PEEP: Only a Dam Against Edema Formation? Probably Not (Again). Am J Respir Crit Care Med. 2018 Nov 06. PMID: 30398892.
      View in: PubMed
    4. Scales DC, Kavanagh BP. Can a Physiologic Insight 'Resuscitate' Research in CPR? Am J Respir Crit Care Med. 2018 Nov 01. PMID: 30383400.
      View in: PubMed
    5. Katira BH, Engelberts D, Otulakowski G, Giesinger RE, Yoshida T, Post M, Kuebler WM, Connelly KA, Kavanagh BP. Abrupt Deflation after Sustained Inflation Causes Lung Injury. Am J Respir Crit Care Med. 2018 Nov 01; 198(9):1165-1176. PMID: 29902384.
      View in: PubMed
    6. Yoshida T, Nakamura MAM, Morais CCA, Amato MBP, Kavanagh BP. Reverse Triggering Causes an Injurious Inflation Pattern during Mechanical Ventilation. Am J Respir Crit Care Med. 2018 Oct 15; 198(8):1096-1099. PMID: 29953244.
      View in: PubMed
    7. Brochard L, Kavanagh BP. Declaration of conflicts of interest: a 'crooked' line towards scientific integrity. Intensive Care Med. 2018 Oct; 44(10):1732-1734. PMID: 30178137.
      View in: PubMed
    8. Laffey JG, Kavanagh BP. Negative trials in critical care: why most research is probably wrong. Lancet Respir Med. 2018 Sep; 6(9):659-660. PMID: 30061048.
      View in: PubMed
    9. Xin Y, Cereda M, Hamedani H, Pourfathi M, Siddiqui S, Meeder N, Kadlecek S, Duncan I, Profka H, Rajaei J, Tustison NJ, Gee JC, Kavanagh BP, Rizi RR. Unstable Inflation Causing Injury. Insight from Prone Position and Paired Computed Tomography Scans. Am J Respir Crit Care Med. 2018 Jul 15; 198(2):197-207. PMID: 29420904.
      View in: PubMed
    10. Otulakowski G, Engelberts D, Post M, Masterson C, Kavanagh BP. Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors. Anesthesiology. 2018 Jul; 129(1):143-153. PMID: 29474201.
      View in: PubMed
    11. Li X, Scales DC, Kavanagh BP. Reply to Abrams et al. and to Duggal and Krishnan. Am J Respir Crit Care Med. 2018 Jul 01; 198(1):141-142. PMID: 29537297.
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    12. Yoshida T, Engelberts D, Otulakowski G, Katira B, Post M, Ferguson ND, Brochard L, Amato MBP, Kavanagh BP. Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model. Anesthesiology. 2018 Jul; 129(1):163-172. PMID: 29708892.
      View in: PubMed
    13. Jain A, Mohamed A, Kavanagh B, Shah PS, Kuipers BCW, El-Khuffash A, Mertens L, Jankov RP, McNamara PJ. Cardiopulmonary Adaptation During First Day of Life in Human Neonates. J Pediatr. 2018 Sep; 200:50-57.e2. PMID: 29803302.
      View in: PubMed
    14. Morais CCA, Koyama Y, Yoshida T, Plens GM, Gomes S, Lima CAS, Ramos OPS, Pereira SM, Kawaguchi N, Yamamoto H, Uchiyama A, Borges JB, Vidal Melo MF, Tucci MR, Amato MBP, Kavanagh BP, Costa ELV, Fujino Y. High Positive End-Expiratory Pressure Renders Spontaneous Effort Noninjurious. Am J Respir Crit Care Med. 2018 May 15; 197(10):1285-1296. PMID: 29323536.
      View in: PubMed
    15. Yoshida T, Amato MBP, Grieco DL, Chen L, Lima CAS, Roldan R, Morais CCA, Gomes S, Costa ELV, Cardoso PFG, Charbonney E, Richard JM, Brochard L, Kavanagh BP. Esophageal Manometry and Regional Transpulmonary Pressure in Lung Injury. Am J Respir Crit Care Med. 2018 Apr 15; 197(8):1018-1026. PMID: 29323931.
      View in: PubMed
    16. Li X, Scales DC, Kavanagh BP. Unproven and Expensive before Proven and Cheap: Extracorporeal Membrane Oxygenation versus Prone Position in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2018 Apr 15; 197(8):991-993. PMID: 29313706.
      View in: PubMed
    17. Yoshida T, Engelberts D, Otulakowski G, Katira B, Ferguson ND, Brochard L, Amato MBP, Kavanagh BP. Continuous negative abdominal pressure: mechanism of action and comparison with prone position. J Appl Physiol (1985). 2018 Jul 01; 125(1):107-116. PMID: 29596015.
      View in: PubMed
    18. Yoshida T, Amato MBP, Kavanagh BP. Understanding spontaneous vs. ventilator breaths: impact and monitoring. Intensive Care Med. 2018 Dec; 44(12):2235-2238. PMID: 29574574.
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    19. Roshdy A, Katira BH, Kuebler WM, Kavanagh BP. Vascular-induced lung injury: another advocate for personalized ARDS management : Discussion on "Inspiratory preload obliteration may injure lungs via cyclical 'on-off' vascular flow". Intensive Care Med. 2018 04; 44(4):540-541. PMID: 29450595.
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    20. Yoshida T, Engelberts D, Otulakowski G, Katira B, Post M, Ferguson ND, Brochard L, Amato MBP, Kavanagh BP. Continuous Negative Abdominal Pressure Recruits Lungs at Lower Distending Pressures. Am J Respir Crit Care Med. 2018 Feb 15; 197(4):534-537. PMID: 28742375.
      View in: PubMed
    21. Stokes WA, Bronsert MR, Meguid RA, Blum MG, Jones BL, Koshy M, Sher DJ, Louie AV, Palma DA, Senan S, Gaspar LE, Kavanagh BD, Rusthoven CG. Post-Treatment Mortality After Surgery and Stereotactic Body Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer. J Clin Oncol. 2018 Mar 01; 36(7):642-651. PMID: 29346041.
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    22. Goligher EC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, Vorona S, Sklar MC, Rittayamai N, Lanys A, Murray A, Brace D, Urrea C, Reid WD, Tomlinson G, Slutsky AS, Kavanagh BP, Brochard LJ, Ferguson ND. Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes. Am J Respir Crit Care Med. 2018 Jan 15; 197(2):204-213. PMID: 28930478.
      View in: PubMed
    23. Otulakowski G, Engelberts D, Post M, Masterson C, Kavanagh BP. Hypercapnic Acidosis Regulates Mer Tyrosine Kinase Receptor Shedding and Activity. Am J Respir Cell Mol Biol. 2018 01; 58(1):132-134. PMID: 29286859.
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    24. Katira BH, Kuebler WM, Kavanagh BP. Inspiratory preload obliteration may injure lungs via cyclical "on-off" vascular flow. Intensive Care Med. 2018 Sep; 44(9):1521-1523. PMID: 29270678.
      View in: PubMed
    25. Katira BH, Giesinger RE, Engelberts D, Zabini D, Kornecki A, Otulakowski G, Yoshida T, Kuebler WM, McNamara PJ, Connelly KA, Kavanagh BP. Adverse Heart-Lung Interactions in Ventilator-induced Lung Injury. Am J Respir Crit Care Med. 2017 12 01; 196(11):1411-1421. PMID: 28795839.
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    26. Laffey JG, Misak C, Kavanagh BP. Acute respiratory distress syndrome. BMJ. 2017 11 16; 359:j5055. PMID: 29146585.
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    27. Yoshida T, Nakahashi S, Nakamura MAM, Koyama Y, Roldan R, Torsani V, De Santis RR, Gomes S, Uchiyama A, Amato MBP, Kavanagh BP, Fujino Y. Volume-controlled Ventilation Does Not Prevent Injurious Inflation during Spontaneous Effort. Am J Respir Crit Care Med. 2017 09 01; 196(5):590-601. PMID: 28212050.
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    28. Laffey JG, Kavanagh BP. Fifty Years of Research in ARDS. Insight into Acute Respiratory Distress Syndrome. From Models to Patients. Am J Respir Crit Care Med. 2017 07 01; 196(1):18-28. PMID: 28146637.
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    29. Cereda M, Xin Y, Hamedani H, Bellani G, Kadlecek S, Clapp J, Guerra L, Meeder N, Rajaei J, Tustison NJ, Gee JC, Kavanagh BP, Rizi RR. Tidal changes on CT and progression of ARDS. Thorax. 2017 11; 72(11):981-989. PMID: 28634220.
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    30. Yoshida T, Fujino Y, Amato MB, Kavanagh BP. Fifty Years of Research in ARDS. Spontaneous Breathing during Mechanical Ventilation. Risks, Mechanisms, and Management. Am J Respir Crit Care Med. 2017 Apr 15; 195(8):985-992. PMID: 27786562.
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    31. Rusthoven CG, Palma DA, Senan S, Kavanagh BD. The Head Start Effect: Will Acute and Delayed Postoperative Mortality Lead to Improved Survival with Stereotactic Body Radiation Therapy for Operable Stage I Non-Small-Cell Lung Cancer? J Clin Oncol. 2017 May 20; 35(15):1749-1751. PMID: 28221860.
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    32. Otulakowski G, Engelberts D, Arima H, Hirate H, Bayir H, Post M, Kavanagh BP. a-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury. Thorax. 2017 06; 72(6):538-549. PMID: 28159772.
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    33. Jackson MW, Palma DA, Camidge DR, Jones BL, Robin TP, Sher DJ, Koshy M, Kavanagh BD, Gaspar LE, Rusthoven CG. The Impact of Postoperative Radiotherapy for Thymoma and Thymic Carcinoma. J Thorac Oncol. 2017 04; 12(4):734-744. PMID: 28126540.
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    34. Rusthoven CG, Jones BL, Kavanagh BD, Pugh TJ. Reply to J.B. Aragon-Ching and D. Dalela et al. J Clin Oncol. 2017 Mar 10; 35(8):916-917. PMID: 27937090.
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    35. Yoshida T, Roldan R, Beraldo MA, Torsani V, Gomes S, De Santis RR, Costa EL, Tucci MR, Lima RG, Kavanagh BP, Amato MB. Spontaneous Effort During Mechanical Ventilation: Maximal Injury With Less Positive End-Expiratory Pressure. Crit Care Med. 2016 08; 44(8):e678-88. PMID: 27002273.
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    36. Deschamps A, Hall R, Grocott H, Mazer CD, Choi PT, Turgeon AF, de Medicis E, Bussières JS, Hudson C, Syed S, Seal D, Herd S, Lambert J, Denault A, Deschamps A, Mutch A, Turgeon A, Denault A, Todd A, Jerath A, Fayad A, Finnegan B, Kent B, Kennedy B, Cuthbertson BH, Kavanagh B, Warriner B, MacAdams C, Lehmann C, Fudorow C, Hudson C, McCartney C, McIsaac D, Dubois D, Campbell D, Mazer D, Neilpovitz D, Rosen D, Cheng D, Drapeau D, Dillane D, Tran D, Mckeen D, Wijeysundera D, Jacobsohn E, Couture E, de Medicis E, Alam F, Abdallah F, Ralley FE, Chung F, Lellouche F, Dobson G, Germain G, Djaiani G, Gilron I, Hare G, Bryson G, Clarke H, McDonald H, Roman-Smith H, Grocott H, Yang H, Douketis J, Paul J, Beaubien J, Bussières J, Pridham J, Armstrong JN, Parlow J, Murkin J, Gamble J, Duttchen K, Karkouti K, Turner K, Baghirzada L, Szabo L, Lalu M, Wasowicz M, Bautista M, Jacka M, Murphy M, Schmidt M, Verret M, Perrault MA, Beaudet N, Buckley N, Choi P, MacDougall P, Jones P, Drolet P, Beaulieu P, Taneja R, Martin R, Hall R, George R, Chun R, McMullen S, Beattie S, Sampson S, Choi S, Kowalski S, McCluskey S, Syed S, Boet S, Ramsay T, Saha T, Mutter T, Chowdhury T, Uppal V, Mckay W. Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial. Anesthesiology. 2016 Apr; 124(4):826-36. PMID: 26808629.
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    37. Zhao J, Yorke ED, Li L, Kavanagh BD, Li XA, Das S, Miften M, Rimner A, Campbell J, Xue J, Jackson A, Grimm J, Milano MT, Spring Kong FM. Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies. Int J Radiat Oncol Biol Phys. 2016 08 01; 95(5):1357-1366. PMID: 27325482.
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    38. Siu E, Tenenbein P, Kavanagh BP. Job shortages in anesthesia: a pro or con? Can J Anaesth. 2016 May; 63(5):529-36. PMID: 26869277.
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    39. Kavanagh BP, Nurok M. Standardized Intensive Care. Protocol Misalignment and Impact Misattribution. Am J Respir Crit Care Med. 2016 Jan 01; 193(1):17-22. PMID: 26393290.
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    40. Cereda M, Xin Y, Meeder N, Zeng J, Jiang Y, Hamedani H, Profka H, Kadlecek S, Clapp J, Deshpande CG, Wu J, Gee JC, Kavanagh BP, Rizi RR. Visualizing the Propagation of Acute Lung Injury. Anesthesiology. 2016 Jan; 124(1):121-31. PMID: 26536308.
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    41. Goligher EC, Kavanagh BP, Rubenfeld GD, Ferguson ND. Physiologic Responsiveness Should Guide Entry into Randomized Controlled Trials. Am J Respir Crit Care Med. 2015 Dec 15; 192(12):1416-9. PMID: 25580530.
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    42. Yoshida T, Boylan JF, Kavanagh BP. What do we treat when we treat ARDS? Intensive Care Med. 2016 Feb; 42(2):284-6. PMID: 26667028.
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    43. Cereda M, Xin Y, Hamedani H, Clapp J, Kadlecek S, Meeder N, Zeng J, Profka H, Kavanagh BP, Rizi RR. Mild loss of lung aeration augments stretch in healthy lung regions. J Appl Physiol (1985). 2016 Feb 15; 120(4):444-54. PMID: 26662053; PMCID: PMC4754623 [Available on 02/15/17].
    44. Amini A, Jones B, Jackson MW, Yeh N, Waxweiler TV, Maroni P, Kavanagh BD, Raben D. Survival Outcomes of Dose-Escalated External Beam Radiotherapy versus Combined Brachytherapy for Intermediate and High Risk Prostate Cancer Using the National Cancer Data Base. J Urol. 2016 May; 195(5):1453-1458. PMID: 26576709.
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    45. Diot Q, Kavanagh B, Vinogradskiy Y, Garg K, Gaspar L, Miften M. Lung deformations and radiation-induced regional lung collapse in patients treated with stereotactic body radiation therapy. Med Phys. 2015 Nov; 42(11):6477-87. PMID: 26520737.
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    46. Goligher EC, Fan E, Herridge MS, Murray A, Vorona S, Brace D, Rittayamai N, Lanys A, Tomlinson G, Singh JM, Bolz SS, Rubenfeld GD, Kavanagh BP, Brochard LJ, Ferguson ND. Evolution of Diaphragm Thickness during Mechanical Ventilation. Impact of Inspiratory Effort. Am J Respir Crit Care Med. 2015 Nov 01; 192(9):1080-8. PMID: 26167730.
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    47. Johung KL, Yeh N, Desai NB, Williams TM, Lautenschlaeger T, Arvold ND, Ning MS, Attia A, Lovly CM, Goldberg S, Beal K, Yu JB, Kavanagh BD, Chiang VL, Camidge DR, Contessa JN. Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastasis. J Clin Oncol. 2016 Jan 10; 34(2):123-9. PMID: 26438117.
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    48. Tosoni A, La Rotta G, Breatnach C, Anand V, Foreman C, Davidson L, Redington AN, Kavanagh BP. Oxygen Delivery and Consumption Are Independent: Evidence from Venoarterial Extracorporeal Membrane Oxygenation in Resuscitated Children. Am J Respir Crit Care Med. 2015 Sep 15; 192(6):765-7. PMID: 26371816.
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    49. Kavanagh BP, Otulakowski G. Anesthetics and Lung Injury: Old Research, New Insights. Anesthesiology. 2015 Aug; 123(2):251-2. PMID: 26068208.
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    50. Yildiz C, Palaniyar N, Otulakowski G, Khan MA, Post M, Kuebler WM, Tanswell K, Belcastro R, Masood A, Engelberts D, Kavanagh BP. Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology. 2015 Apr; 122(4):864-75. PMID: 25665049.
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    51. Goligher EC, Laghi F, Detsky ME, Farias P, Murray A, Brace D, Brochard LJ, Bolz SS, Rubenfeld GD, Kavanagh BP, Ferguson ND. Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med. 2015 Apr; 41(4):734. PMID: 25749574.
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    52. Goligher EC, Laghi F, Detsky ME, Farias P, Murray A, Brace D, Brochard LJ, Bolz SS, Sebastien-Bolz S, Rubenfeld GD, Kavanagh BP, Ferguson ND. Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med. 2015 Apr; 41(4):642-9. PMID: 25693448.
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    53. Masterson C, Otulakowski G, Kavanagh BP. Hypercapnia: clinical relevance and mechanisms of action. Curr Opin Crit Care. 2015 Feb; 21(1):7-12. PMID: 25546531.
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    54. Goldenberg NM, Steinberg BE, Lee WL, Wijeysundera DN, Kavanagh BP. In reply. Anesthesiology. 2015 Feb; 122(2):473-4. PMID: 25603215.
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    55. Kavanagh BP, Suffredini AF. Management of pediatric septic shock. Progress through applied insight. Am J Respir Crit Care Med. 2015 Feb 01; 191(3):247-8. PMID: 25635486; PMCID: PMC4351584.
    56. Otulakowski G, Engelberts D, Gusarova GA, Bhattacharya J, Post M, Kavanagh BP. Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17. J Physiol. 2014 Oct 15; 592(20):4507-21. PMID: 25085885; PMCID: PMC4287739.
    57. Goldenberg NM, Steinberg BE, Lee WL, Wijeysundera DN, Kavanagh BP. Lung-protective ventilation in the operating room: time to implement? Anesthesiology. 2014 Jul; 121(1):184-8. PMID: 24781494.
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    58. Goligher EC, Kavanagh BP, Rubenfeld GD, Adhikari NK, Pinto R, Fan E, Brochard LJ, Granton JT, Mercat A, Marie Richard JC, Chretien JM, Jones GL, Cook DJ, Stewart TE, Slutsky AS, Meade MO, Ferguson ND. Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med. 2014 Jul 01; 190(1):70-6. PMID: 24919111.
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    59. Downar J, Sibbald RW, Bailey TM, Kavanagh BP. Withholding and withdrawing treatment in Canada: implications of the Supreme Court of Canada's decision in the Rasouli case. CMAJ. 2014 Nov 04; 186(16):E622-6. PMID: 24958840; PMCID: PMC4216277.
    60. Jaecklin T, Duerr J, Huang H, Rafii M, Bear CE, Ratjen F, Pencharz P, Kavanagh BP, Mall MA, Grasemann H. Lung arginase expression and activity is increased in cystic fibrosis mouse models. J Appl Physiol (1985). 2014 Aug 01; 117(3):284-8. PMID: 24925982.
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    61. Anand V, Scales DC, Parshuram CS, Kavanagh BP. Registration and design alterations of clinical trials in critical care: a cross-sectional observational study. Intensive Care Med. 2014 May; 40(5):700-22. PMID: 24737256.
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    62. McNamara PJ, Engelberts D, Finelli M, Adeli K, Kavanagh BP. Vasopressin improves survival compared with epinephrine in a neonatal piglet model of asphyxial cardiac arrest. Pediatr Res. 2014 Jun; 75(6):738-48. PMID: 24614799.
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    63. Cereda M, Kavanagh BP. Compartmentalization of lung injury--atelectasis versus overstretch. Crit Care Med. 2014 Jan; 42(1):223-4. PMID: 24346539.
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    64. Yoshida T, Torsani V, Gomes S, De Santis RR, Beraldo MA, Costa EL, Tucci MR, Zin WA, Kavanagh BP, Amato MB. Spontaneous effort causes occult pendelluft during mechanical ventilation. Am J Respir Crit Care Med. 2013 Dec 15; 188(12):1420-7. PMID: 24199628.
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    65. Cereda M, Xin Y, Emami K, Huang J, Rajaei J, Profka H, Han B, Mongkolwisetwara P, Kadlecek S, Kuzma NN, Pickup S, Kavanagh BP, Deutschman CS, Rizi RR. Positive end-expiratory pressure increments during anesthesia in normal lung result in hysteresis and greater numbers of smaller aerated airspaces. Anesthesiology. 2013 Dec; 119(6):1402-9. PMID: 24025616; PMCID: PMC3987989.
    66. de Prost N, Costa EL, Wellman T, Musch G, Tucci MR, Winkler T, Harris R, Venegas JG, Kavanagh BP, Vidal Melo MF. Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care. 2013 Aug 15; 17(4):R175. PMID: 23947920; PMCID: PMC4056777.
    67. Kroon AA, Delriccio V, Tseu I, Kavanagh BP, Post M. Mechanical ventilation-induced apoptosis in newborn rat lung is mediated via FasL/Fas pathway. Am J Physiol Lung Cell Mol Physiol. 2013 Dec; 305(11):L795-804. PMID: 23934924.
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    68. Curley GF, Laffey JG, Kavanagh BP. CrossTalk proposal: there is added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol. 2013 Jun 01; 591(11):2763-5. PMID: 23729790; PMCID: PMC3690679.
    69. Curley GF, Laffey JG, Kavanagh BP. Rebuttal from Gerard F. Curley, John G. Laffey and Brian P. Kavanagh. J Physiol. 2013 Jun 01; 591(11):2771-2. PMID: 23729792; PMCID: PMC3690681.
    70. Cereda M, Emami K, Xin Y, Kadlecek S, Kuzma NN, Mongkolwisetwara P, Profka H, Pickup S, Ishii M, Kavanagh BP, Deutschman CS, Rizi RR. Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med. 2013 Feb; 41(2):527-35. PMID: 23263577; PMCID: PMC3557664.
    71. Uematsu S, Engelberts D, Peltekova V, Otulakowski G, Post M, Kavanagh BP. Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med. 2013 Jan; 41(1):151-8. PMID: 23128385.
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    72. Weickhardt AJ, Scheier B, Burke JM, Gan G, Lu X, Bunn PA, Aisner DL, Gaspar LE, Kavanagh BD, Doebele RC, Camidge DR. Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non-small-cell lung cancer. J Thorac Oncol. 2012 Dec; 7(12):1807-1814. PMID: 23154552.
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    73. Kavanagh BP. Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med. 2012 Sep 27; 367(13):1259-60. PMID: 22957522.
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    74. Goligher EC, Ferguson ND, Kavanagh BP. Ventilator-induced diaphragm dysfunction: from mice (hopefully) to men. Anesthesiology. 2012 Sep; 117(3):463-4. PMID: 22743524.
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    75. Chierichetti M, Engelberts D, El-Khuffash A, Babyn P, Post M, Kavanagh BP. Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med. 2012 Jun; 40(6):1864-72. PMID: 22610189.
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    76. Tonelli MR, Curtis JR, Guntupalli KK, Rubenfeld GD, Arroliga AC, Brochard L, Douglas IS, Gutterman DD, Hall JR, Kavanagh BP, Mancebo J, Misak CJ, Simpson SQ, Slutsky AS, Suffredini AF, Thompson BT, Ware LB, Wheeler AP, Levy MM. An official multi-society statement: the role of clinical research results in the practice of critical care medicine. Am J Respir Crit Care Med. 2012 May 15; 185(10):1117-24. PMID: 22589312.
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    77. Peng G, Ivanovska J, Kantores C, Van Vliet T, Engelberts D, Kavanagh BP, Enomoto M, Belik J, Jain A, McNamara PJ, Jankov RP. Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Heart Circ Physiol. 2012 Jun 15; 302(12):H2599-611. PMID: 22505643.
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    78. Engelberts D, Malhotra A, Butler JP, Topulos GP, Loring SH, Kavanagh BP. Relative effects of negative versus positive pressure ventilation depend on applied conditions. Intensive Care Med. 2012 May; 38(5):879-85. PMID: 22349427; PMCID: PMC3463870.
    79. Ngiam N, Kavanagh BP. Ventilator-induced lung injury: the role of gene activation. Curr Opin Crit Care. 2012 Feb; 18(1):16-22. PMID: 22157252.
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    80. Walsh MA, Merat M, La Rotta G, Joshi P, Joshi V, Tran T, Jarvis S, Caldarone CA, Van Arsdell GS, Redington AN, Kavanagh BP. Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med. 2011 Dec; 39(12):2599-604. PMID: 21765348.
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    81. Otulakowski G, Kavanagh BP. Hypercapnia in acute illness: sometimes good, sometimes not. Crit Care Med. 2011 Jun; 39(6):1581-2. PMID: 21610635.
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    82. Boylan JF, Kavanagh BP, Armitage J. Randomised controlled trials: important but overrated? J R Coll Physicians Edinb. 2011 Jun; 41(2):126-31. PMID: 21677918.
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    83. Bersten AD, Kavanagh BP. A metabolic window into acute respiratory distress syndrome: stretch, the "baby" lung, and atelectrauma. Am J Respir Crit Care Med. 2011 May 01; 183(9):1120-2. PMID: 21531950.
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    84. Wijeysundera DN, Kavanagh BP. Prevention of pain from propofol injection. BMJ. 2011 Mar 15; 342:d1102. PMID: 21406528.
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    85. Kroon AA, Wang J, Kavanagh BP, Kavanagh B, Huang Z, Kuliszewski M, van Goudoever JB, Post M. Prolonged mechanical ventilation induces cell cycle arrest in newborn rat lung. PLoS One. 2011 Feb 16; 6(2):e16910. PMID: 21359218; PMCID: PMC3040197.
    86. Jaecklin T, Engelberts D, Otulakowski G, O'Brodovich H, Post M, Kavanagh BP. Lung-derived soluble mediators are pathogenic in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L648-58. PMID: 21239530.
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    87. Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: Evidence for harm. Crit Care Med. 2011 Jan; 39(1):229-30. PMID: 21178560.
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    88. Kavanagh BP, McCowen KC. Clinical practice. Glycemic control in the ICU. N Engl J Med. 2010 Dec 23; 363(26):2540-6. PMID: 21175316.
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    89. Niitsu T, Tsuchida S, Peltekova V, Engelberts D, Copland I, Otulakowski G, Post M, Kavanagh BP. Cyclooxygenase inhibition in ventilator-induced lung injury. Anesth Analg. 2011 Jan; 112(1):143-9. PMID: 21048090.
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    90. Deegan CA, Murray D, Doran P, Moriarty DC, Sessler DI, Mascha E, Kavanagh BP, Buggy DJ. Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med. 2010 Nov-Dec; 35(6):490-5. PMID: 20975461.
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    91. Xu EZ, Kantores C, Ivanovska J, Engelberts D, Kavanagh BP, McNamara PJ, Jankov RP. Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2010 Dec; 299(6):H1854-64. PMID: 20889845.
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    92. Hare GM, Kavanagh BP. Hypoxemia during surgery: learning from history, science, and current practice. Can J Anaesth. 2010 Oct; 57(10):877-81. PMID: 20661678.
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    93. Zhang L, Kavanagh BD, Thorburn AM, Camidge DR. Preclinical and clinical estimates of the basal apoptotic rate of a cancer predict the amount of apoptosis induced by subsequent proapoptotic stimuli. Clin Cancer Res. 2010 Sep 01; 16(17):4478-89. PMID: 20630997.
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    94. Otulakowski G, Kavanagh BP. Hydrogen sulfide in lung injury: therapeutic hope from a toxic gas? Anesthesiology. 2010 Jul; 113(1):4-6. PMID: 20574223.
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    95. Duggan M, Kavanagh BP. Perioperative modifications of respiratory function. Best Pract Res Clin Anaesthesiol. 2010 Jun; 24(2):145-55. PMID: 20608553.
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    96. Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: more harm than benefit. Crit Care Med. 2010 May; 38(5):1348-59. PMID: 20228681.
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    97. Curley G, Laffey JG, Kavanagh BP. Bench-to-bedside review: carbon dioxide. Crit Care. 2010; 14(2):220. PMID: 20497620; PMCID: PMC2887152.
    98. Skrobik Y, Ahern S, Leblanc M, Marquis F, Awissi DK, Kavanagh BP. Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg. 2010 Aug; 111(2):451-63. PMID: 20375300.
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    99. Jaecklin T, Otulakowski G, Kavanagh BP. Do soluble mediators cause ventilator-induced lung injury and multi-organ failure? Intensive Care Med. 2010 May; 36(5):750-7. PMID: 20232037.
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    100. Peltekova V, Engelberts D, Otulakowski G, Uematsu S, Post M, Kavanagh BP. Hypercapnic acidosis in ventilator-induced lung injury. Intensive Care Med. 2010 May; 36(5):869-78. PMID: 20213072.
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    101. Dawson LA, Kavanagh BD, Paulino AC, Das SK, Miften M, Li XA, Pan C, Ten Haken RK, Schultheiss TE. Radiation-associated kidney injury. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3 Suppl):S108-15. PMID: 20171504.
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    102. Kavanagh BD, Pan CC, Dawson LA, Das SK, Li XA, Ten Haken RK, Miften M. Radiation dose-volume effects in the stomach and small bowel. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3 Suppl):S101-7. PMID: 20171503.
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    103. Pan CC, Kavanagh BD, Dawson LA, Li XA, Das SK, Miften M, Ten Haken RK. Radiation-associated liver injury. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3 Suppl):S94-100. PMID: 20171524; PMCID: PMC4388033.
    104. Ngiam N, Peltekova V, Engelberts D, Otulakowski G, Post M, Kavanagh BP. Early growth response-1 worsens ventilator-induced lung injury by up-regulating prostanoid synthesis. Am J Respir Crit Care Med. 2010 May 01; 181(9):947-56. PMID: 20110555.
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    105. McCaul C, Kornecki A, Engelberts D, McNamara P, Kavanagh BP. Positive end-expiratory pressure improves survival in a rodent model of cardiopulmonary resuscitation using high-dose epinephrine. Anesth Analg. 2009 Oct; 109(4):1202-8. PMID: 19762750.
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    106. Kavanagh BP. The GRADE system for rating clinical guidelines. PLoS Med. 2009 Sep; 6(9):e1000094. PMID: 19753107; PMCID: PMC2735782.
    107. Masood A, Yi M, Lau M, Belcastro R, Shek S, Pan J, Kantores C, McNamara PJ, Kavanagh BP, Belik J, Jankov RP, Tanswell AK. Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats. Am J Physiol Lung Cell Mol Physiol. 2009 Nov; 297(5):L920-30. PMID: 19749000.
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    108. Boylan JF, Kavanagh BP. Emergency airway management: competence versus expertise? Anesthesiology. 2008 Dec; 109(6):945-7. PMID: 19034086.
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    109. Boylan JF, Kavanagh BP. The name of the game: no transfusion (or nontransfusion) by cookbook. Anesthesiology. 2008 Oct; 109(4):745-6; author reply 747. PMID: 18813056.
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    110. Helm E, Talakoub O, Grasso F, Engelberts D, Alirezaie J, Kavanagh BP, Babyn P. Use of dynamic CT in acute respiratory distress syndrome (ARDS) with comparison of positive and negative pressure ventilation. Eur Radiol. 2009 Jan; 19(1):50-7. PMID: 18651149.
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    111. Kornecki A, Engelberts D, McNamara P, Jankov RP, McCaul C, Ackerley C, Post M, Kavanagh BP. Vascular remodeling protects against ventilator-induced lung injury in the in vivo rat. Anesthesiology. 2008 Jun; 108(6):1047-54. PMID: 18497605.
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    112. Kavanagh BP. Perioperative atelectasis. Minerva Anestesiol. 2008 Jun; 74(6):285-7. PMID: 18500199.
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    113. Marik PE, Pastores SM, Kavanagh BP. Corticosteroids for septic shock. N Engl J Med. 2008 May 08; 358(19):2069-70; author reply 2070-1. PMID: 18467976.
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    114. Grasso F, Engelberts D, Helm E, Frndova H, Jarvis S, Talakoub O, McKerlie C, Babyn P, Post M, Kavanagh BP. Negative-pressure ventilation: better oxygenation and less lung injury. Am J Respir Crit Care Med. 2008 Feb 15; 177(4):412-8. PMID: 18079496.
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    115. McNamara PJ, Murthy P, Kantores C, Teixeira L, Engelberts D, van Vliet T, Kavanagh BP, Jankov RP. Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol. 2008 Feb; 294(2):L205-13. PMID: 18032699.
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    116. Grasselli G, Gattinoni L, Kavanagh B, Latini R, Laupacis A, Lemaire F, Pesenti A, Suter P, Slutsky A, Tognoni G. Feasibility, limits and problems of clinical studies in Intensive Care Unit. Minerva Anestesiol. 2007 Nov; 73(11):595-601. PMID: 17952032.
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    117. Ngiam N, Post M, Kavanagh BP. Early growth response factor-1 in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2007 Nov; 293(5):L1089-91. PMID: 17766585.
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    118. Albuali WH, Singh RN, Fraser DD, Seabrook JA, Kavanagh BP, Parshuram CS, Kornecki A. Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med. 2007 Jul; 8(4):324-30. PMID: 17545937.
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    119. Ouimet S, Riker R, Bergeron N, Bergeon N, Cossette M, Kavanagh B, Skrobik Y. Subsyndromal delirium in the ICU: evidence for a disease spectrum. Intensive Care Med. 2007 Jun; 33(6):1007-13. PMID: 17404704.
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    120. Kuhle S, Eulmesekian P, Kavanagh B, Massicotte P, Vegh P, Lau A, Mitchell LG. Lack of correlation between heparin dose and standard clinical monitoring tests in treatment with unfractionated heparin in critically ill children. Haematologica. 2007 Apr; 92(4):554-7. PMID: 17488668.
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    121. Duggan M, Kavanagh BP. Atelectasis in the perioperative patient. Curr Opin Anaesthesiol. 2007 Feb; 20(1):37-42. PMID: 17211165.
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    122. Kuhle S, Eulmesekian P, Kavanagh B, Massicotte P, Vegh P, Mitchell LG. A clinically significant incidence of bleeding in critically ill children receiving therapeutic doses of unfractionated heparin: a prospective cohort study. Haematologica. 2007 Feb; 92(2):244-7. PMID: 17296576.
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    123. Ouimet S, Kavanagh BP, Gottfried SB, Skrobik Y. Incidence, risk factors and consequences of ICU delirium. Intensive Care Med. 2007 Jan; 33(1):66-73. PMID: 17102966.
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    124. El-Beheiry H, Kavanagh B. Is propofol neurotoxic to the developing brain? Can J Anaesth. 2006 Nov; 53(11):1069-73. PMID: 17079631.
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    125. Beheiry HE, Kavanagh B. Is propofol neurotoxic to the developing brain? Can J Anaesth. 2006 11; 53(11):1069. PMID: 27771905.
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    126. Kantores C, McNamara PJ, Teixeira L, Engelberts D, Murthy P, Kavanagh BP, Jankov RP. Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol. 2006 Nov; 291(5):L912-22. PMID: 16829630.
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    127. Kavanagh BP, Laffey JG. Hypercapnia: permissive and therapeutic. Minerva Anestesiol. 2006 Jun; 72(6):567-76. PMID: 16682931.
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    128. Tsuchida S, Engelberts D, Peltekova V, Hopkins N, Frndova H, Babyn P, McKerlie C, Post M, McLoughlin P, Kavanagh BP. Atelectasis causes alveolar injury in nonatelectatic lung regions. Am J Respir Crit Care Med. 2006 Aug 01; 174(3):279-89. PMID: 16675780.
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    129. Skrobik Y, Kavanagh BP. Scoring systems for the critically ill: use, misuse and abuse. Can J Anaesth. 2006 May; 53(5):432-6. PMID: 16636025.
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    130. McCaul CL, McNamara PJ, Engelberts D, Wilson GJ, Romaschin A, Redington AN, Kavanagh BP. Epinephrine increases mortality after brief asphyxial cardiac arrest in an in vivo rat model. Anesth Analg. 2006 Feb; 102(2):542-8. PMID: 16428558.
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    131. McCaul CL, McNamara P, Engelberts D, Slorach C, Hornberger LK, Kavanagh BP. The effect of global hypoxia on myocardial function after successful cardiopulmonary resuscitation in a laboratory model. Resuscitation. 2006 Feb; 68(2):267-75. PMID: 16325315.
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    132. McCaul CL, Harney D, Ryan M, Moran C, Kavanagh BP, Boylan JF. Airway management in the lateral position: a randomized controlled trial. Anesth Analg. 2005 Oct; 101(4):1221-5, table of contents. PMID: 16192549.
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    133. Duggan M, McNamara PJ, Engelberts D, Pace-Asciak C, Babyn P, Post M, Kavanagh BP. Oxygen attenuates atelectasis-induced injury in the in vivo rat lung. Anesthesiology. 2005 Sep; 103(3):522-31. PMID: 16129977.
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    134. Kavanagh BP, Roy L. Pediatric ventilation -- towards simpler approaches for complex diseases. Paediatr Anaesth. 2005 Aug; 15(8):627-9. PMID: 16029396.
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    135. Kavanagh BP, Meyer LJ. Normalizing physiological variables in acute illness: five reasons for caution. Intensive Care Med. 2005 Sep; 31(9):1161-7. PMID: 16044251.
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    136. Kavanagh BP. Prone positioning in children with ARDS: positive reflections on a negative clinical trial. JAMA. 2005 Jul 13; 294(2):248-50. PMID: 16014601.
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    137. Tsuchida S, Engelberts D, Roth M, McKerlie C, Post M, Kavanagh BP. Continuous positive airway pressure causes lung injury in a model of sepsis. Am J Physiol Lung Cell Mol Physiol. 2005 Oct; 289(4):L554-64. PMID: 15923208.
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    138. Duggan M, Kavanagh BP. Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology. 2005 Apr; 102(4):838-54. PMID: 15791115.
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    139. Pong S, Seto W, Abdolell M, Trope A, Wong K, Herridge J, Harvey E, Kavanagh BP. 12-hour versus 24-hour creatinine clearance in critically ill pediatric patients. Pediatr Res. 2005 Jul; 58(1):83-8. PMID: 15774853.
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    140. Duggan M, Engelberts D, Jankov RP, Worrall JM, Qu R, Hare GM, Tanswell AK, Mullen JB, Kavanagh BP. Hypocapnia attenuates mesenteric ischemia-reperfusion injury in a rat model. Can J Anaesth. 2005 Mar; 52(3):262-8. PMID: 15753497.
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    141. Kavanagh BP. Therapeutic hypercapnia: careful science, better trials. Am J Respir Crit Care Med. 2005 Jan 15; 171(2):96-7. PMID: 15640370.
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    142. Kornecki A, Tsuchida S, Ondiveeran HK, Engelberts D, Frndova H, Tanswell AK, Post M, McKerlie C, Belik J, Fox-Robichaud A, Kavanagh BP. Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):743-52. PMID: 15640366.
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    143. Parshuram CS, Kavanagh BP. Positive clinical trials: understand the control group before implementing the result. Am J Respir Crit Care Med. 2004 Aug 01; 170(3):223-6. PMID: 15151921.
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    144. Martinez F, Lewis J, Copland I, Engelberts D, Kavanagh BP, Post M, Schurch S, Belik J. Mechanical ventilation effect on surfactant content, function, and lung compliance in the newborn rat. Pediatr Res. 2004 Jul; 56(1):19-25. PMID: 15128929.
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    145. Laffey JG, O'Croinin D, McLoughlin P, Kavanagh BP. Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med. 2004 Mar; 30(3):347-56. PMID: 14722644.
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    146. Copland IB, Martinez F, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M. High tidal volume ventilation causes different inflammatory responses in newborn versus adult lung. Am J Respir Crit Care Med. 2004 Mar 15; 169(6):739-48. PMID: 14711797.
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    147. Laffey JG, Jankov RP, Engelberts D, Tanswell AK, Post M, Lindsay T, Mullen JB, Romaschin A, Stephens D, McKerlie C, Kavanagh BP. Effects of therapeutic hypercapnia on mesenteric ischemia-reperfusion injury. Am J Respir Crit Care Med. 2003 Dec 01; 168(11):1383-90. PMID: 14644926.
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    148. Hare GM, Kavanagh BP, Mazer CD, Hum KM, Kim SY, Coackley C, Barr A, Baker AJ. Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats. Can J Anaesth. 2003 Dec; 50(10):1061-8. PMID: 14656789.
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    149. Laffey JG, Engelberts D, Duggan M, Veldhuizen R, Lewis JF, Kavanagh BP. Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med. 2003 Nov; 31(11):2634-40. PMID: 14605535.
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    150. Rai S, Engelberts D, Laffey JG, Frevert C, Kajikawa O, Martin TR, Post M, Kavanagh BP. Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res. 2004 Jan; 55(1):42-9. PMID: 14561781.
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    151. Copland IB, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M. Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med. 2003 Nov 01; 168(9):1051-9. PMID: 12816737.
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    152. Kavanagh BP. Lung recruitment in real time: learning was never so easy. Am J Respir Crit Care Med. 2003 Jun 15; 167(12):1585-6. PMID: 12796049.
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    153. Chiu P, Kavanagh B. The use of the intensive care unit as an environment for minor procedures in noncritically ill children. Crit Care Med. 2003 Jun; 31(6):1891; author reply 1891. PMID: 12794451.
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    154. Duggan M, McCaul CL, McNamara PJ, Engelberts D, Ackerley C, Kavanagh BP. Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med. 2003 Jun 15; 167(12):1633-40. PMID: 12663325.
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    155. Parshuram C, Kavanagh B. Meta-analysis of tidal volumes in ARDS. Am J Respir Crit Care Med. 2003 Mar 01; 167(5):798; author reply 798-800. PMID: 12598221.
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    156. Sawchuk CW, Wong DT, Kavanagh BP, Siu SC. Transthoracic echocardiography does not improve prediction of outcome over APACHE II in medical-surgical intensive care. Can J Anaesth. 2003 Mar; 50(3):305-10. PMID: 12620957.
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    157. Grisaru-Soen G, Coles JG, Kavanagh BP, Arnold SR. Rupture of the common carotid artery after extracorporeal membrane oxygenation. Ann Thorac Surg. 2002 Nov; 74(5):1697-8. PMID: 12440637.
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    158. Anton N, Hitzler JK, Kavanagh BP. Treatment of life-threatening post-haemorrhagic anaemia with cell-free haemoglobin solution in an adolescent Jehovah's Witness. Br J Haematol. 2002 Sep; 118(4):1183-6. PMID: 12199805.
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    159. Laffey JG, Kavanagh BP. Hypocapnia. N Engl J Med. 2002 Jul 04; 347(1):43-53. PMID: 12097540.
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    160. Skrobik Y, Kavanagh B, Mazer D, Cook D. Toronto Critical Care Medicine Symposium report. Can J Anaesth. 2002 May; 49(5):513-6. PMID: 11983671.
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    161. Kavanagh B. Normocapnia vs hypercapnia. Minerva Anestesiol. 2002 May; 68(5):346-50. PMID: 12029243.
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    162. Kavanagh BD, Khandelwal SR, Schmidt-Ullrich RK, Roberts JD, Shaw EG, Pearlman AD, Venitz J, Dusenbery KE, Abraham DJ, Gerber MJ. A phase I study of RSR13, a radiation-enhancing hemoglobin modifier: tolerance of repeated intravenous doses and correlation of pharmacokinetics with pharmacodynamics. Int J Radiat Oncol Biol Phys. 2001 Mar 15; 49(4):1133-9. PMID: 11240256.
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    163. Laffey JG, Tanaka M, Engelberts D, Luo X, Yuan S, Tanswell AK, Post M, Lindsay T, Kavanagh BP. Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion. Am J Respir Crit Care Med. 2000 Dec; 162(6):2287-94. PMID: 11112153.
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    164. Laffey JG, Kavanagh BP. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury. N Engl J Med. 2000 Sep 14; 343(11):812; author reply 813-4. PMID: 10991704.
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    165. Laffey JG, Engelberts D, Kavanagh BP. Injurious effects of hypocapnic alkalosis in the isolated lung. Am J Respir Crit Care Med. 2000 Aug; 162(2 Pt 1):399-405. PMID: 10934060.
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    166. Murphy DB, Cregg N, Tremblay L, Engelberts D, Laffey JG, Slutsky AS, Romaschin A, Kavanagh BP. Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin. Am J Respir Crit Care Med. 2000 Jul; 162(1):27-33. PMID: 10903215.
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    167. Manning MA, Cardinale RM, Benedict SH, Kavanagh BD, Zwicker RD, Amir C, Broaddus WC. Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases. Int J Radiat Oncol Biol Phys. 2000 Jun 01; 47(3):603-8. PMID: 10837942.
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    168. Laffey JG, Kavanagh BP. Biological effects of hypercapnia. Intensive Care Med. 2000 Jan; 26(1):133-8. PMID: 10663296.
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    169. Laffey JG, Engelberts D, Kavanagh BP. Buffering hypercapnic acidosis worsens acute lung injury. Am J Respir Crit Care Med. 2000 Jan; 161(1):141-6. PMID: 10619811.
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    170. Mao C, Wong DT, Slutsky AS, Kavanagh BP. A quantitative assessment of how Canadian intensivists believe they utilize oxygen in the intensive care unit. Crit Care Med. 1999 Dec; 27(12):2806-11. PMID: 10628630.
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    171. Laffey JG, Kavanagh BP. Carbon dioxide and the critically ill--too little of a good thing? Lancet. 1999 Oct 09; 354(9186):1283-6. PMID: 10520649.
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    172. Kavanagh BP, Slutsky AS. Ventilator-induced lung injury: more studies, more questions. Crit Care Med. 1999 Aug; 27(8):1669-71. PMID: 10470791.
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    173. Wong DT, Gomez M, McGuire GP, Kavanagh B. Utilization of intensive care unit days in a Canadian medical-surgical intensive care unit. Crit Care Med. 1999 Jul; 27(7):1319-24. PMID: 10446826.
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    174. Kavanagh BP. Anemia, hypoxia and hypercapnia thresholds. Lessons from physiological limits in critically ill patients. Can J Anaesth. 1999 May; 46(5 Pt 2):R145-55. PMID: 10370839.
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    175. Patterson KW, Deb B, Kavanagh BP, Pearl RG. Inhaled nitric oxide potentiates actions of adenosine but not of sodium nitroprusside in experimental pulmonary hypertension. Pharmacology. 1999 May; 58(5):246-51. PMID: 10087465.
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    176. Nishida O, Arellano R, Cheng DC, DeMajo W, Kavanagh BP. Gas exchange and hemodynamics in experimental pleural effusion. Crit Care Med. 1999 Mar; 27(3):583-7. PMID: 10199540.
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    177. Khandelwal SR, Kavanagh BD, Lin PS, Truong QT, Lu J, Abraham DJ, Schmidt-Ullrich RK. RSR13, an allosteric effector of haemoglobin, and carbogen radiosensitize FSAII and SCCVII tumours in C3H mice. Br J Cancer. 1999 Feb; 79(5-6):814-20. PMID: 10070874; PMCID: PMC2362693.
    178. Wall MH, Patterson KW, Kavanagh BP, Pearl RG. Inhibition of endogenous nitric oxide synthesis potentiates the effects of sodium nitroprusside but not of adenosine in experimental pulmonary hypertension. Pharmacology. 1999 Jan; 58(1):34-43. PMID: 9831829.
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    179. Shibata K, Cregg N, Engelberts D, Takeuchi A, Fedorko L, Kavanagh BP. Hypercapnic acidosis may attenuate acute lung injury by inhibition of endogenous xanthine oxidase. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 1):1578-84. PMID: 9817711.
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    180. Boylan JF, Katz J, Kavanagh BP, Klinck JR, Cheng DC, DeMajo WC, Walker PM, Johnston KW, Sandler AN. Epidural bupivacaine-morphine analgesia versus patient-controlled analgesia following abdominal aortic surgery: analgesic, respiratory, and myocardial effects. Anesthesiology. 1998 Sep; 89(3):585-93. PMID: 9743393.
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    181. Thompson JS, Kavanagh BP, Pearl RG. Nitroglycerin does not alter pulmonary vascular permeability in isolated rabbit lungs. Anesth Analg. 1997 Feb; 84(2):359-62. PMID: 9024029.
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    182. Saccomanno PM, Kavanagh BP, Cheng DC, Katz J, Sandler AN. Comparison of lorazepam alone vs lorazepam, morphine, and perphenazine for cardiac premedication. Can J Anaesth. 1997 Feb; 44(2):146-53. PMID: 9043726.
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    183. Katz J, Clairoux M, Redahan C, Kavanagh BP, Carroll S, Nierenberg H, Jackson M, Beattie J, Taddio A, Sandler AN. High dose alfentanil pre-empts pain after abdominal hysterectomy. Pain. 1996 Nov; 68(1):109-18. PMID: 9252005.
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    184. Kavanagh BP, Thompson JS, Pearl RG. Inhibition of endogenous nitric oxide synthase potentiates nitrovasodilators in experimental pulmonary hypertension. Anesthesiology. 1996 Oct; 85(4):860-6. PMID: 8873557.
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    185. Goldsmith JA, Kavanagh BP, Pearl RG. Plasma potentiates the priming effects of endotoxin on platelet activating factor-induced pulmonary hypertension in the rabbit lung. Anesth Analg. 1996 Aug; 83(2):242-6. PMID: 8694300.
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    186. Katz J, Jackson M, Kavanagh BP, Sandler AN. Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain. 1996 Mar; 12(1):50-5. PMID: 8722735.
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    187. Kavanagh BP, Pearl RG. Inhaled nitric oxide in anesthesia and critical care medicine. Int Anesthesiol Clin. 1995; 33(1):181-210. PMID: 7635555.
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    188. Lindeborg DM, Kavanagh BP, Van Meurs K, Pearl RG. Inhaled nitric oxide does not alter the longitudinal distribution of pulmonary vascular resistance. J Appl Physiol (1985). 1995 Jan; 78(1):341-8. PMID: 7713835.
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    189. Katz J, Clairoux M, Kavanagh BP, Roger S, Nierenberg H, Redahan C, Sandler AN. Pre-emptive lumbar epidural anaesthesia reduces postoperative pain and patient-controlled morphine consumption after lower abdominal surgery. Pain. 1994 Dec; 59(3):395-403. PMID: 7708414.
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    190. Kavanagh BP, Katz J, Sandler AN. Pain control after thoracic surgery. A review of current techniques. Anesthesiology. 1994 Sep; 81(3):737-59. PMID: 8092520.
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    191. Kavanagh BP, Katz J, Sandler AN, Nierenberg H, Roger S, Boylan JF, Laws AK. Multimodal analgesia before thoracic surgery does not reduce postoperative pain. Br J Anaesth. 1994 Aug; 73(2):184-9. PMID: 7917733.
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    192. Mouchawar AM, Kavanagh BP, Pearl RG. Serum but not plasma produces injury in the perfused rabbit lung. Anesth Analg. 1994 Jul; 79(1):40-5. PMID: 8010452.
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    193. Kavanagh BP, Mouchawar A, Goldsmith J, Pearl RG. Effects of inhaled NO and inhibition of endogenous NO synthesis in oxidant-induced acute lung injury. J Appl Physiol (1985). 1994 Mar; 76(3):1324-9. PMID: 8005878.
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    194. Friedlander M, Sandler A, Kavanagh B, Winton T, Benumof J. Is hypoxic pulmonary vasoconstriction important during single lung ventilation in the lateral decubitus position? Can J Anaesth. 1994 Jan; 41(1):26-30. PMID: 8111940.
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    195. Kavanagh BP, Cheng DC, Sandler AN, Chung F, Lawson S, Ong D. Supplemental oxygen does not reduce myocardial ischemia in premedicated patients with critical coronary artery disease. Anesth Analg. 1993 May; 76(5):950-6. PMID: 8484550.
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    196. Kavanagh BD, Coffey BE, Needham D, Hochmuth RM, Dewhirst MW. The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment. Br J Cancer. 1993 Apr; 67(4):734-41. PMID: 8471430; PMCID: PMC1968366.
    197. Katz J, Kavanagh BP, Clairoux M, Sandler AN. Pre-emptive analgesia. Br J Anaesth. 1993 Mar; 70(3):378-9. PMID: 8471388.
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    198. Katz J, Kavanagh BP, Sandler AN. Effect of preoperative opioid administration on postoperative pain. Br J Anaesth. 1992 Oct; 69(4):424-5. PMID: 1419463.
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    199. Katz J, Kavanagh BP, Sandler AN. Does pre-operative fentanyl administration influence postoperative analgesia? Pain. 1992 Oct; 51(1):123-4. PMID: 1454397.
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    200. Katz J, Kavanagh BP, Sandler AN, Nierenberg H, Boylan JF, Friedlander M, Shaw BF. Preemptive analgesia. Clinical evidence of neuroplasticity contributing to postoperative pain. Anesthesiology. 1992 Sep; 77(3):439-46. PMID: 1519781.
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    201. Kavanagh BP, Sandler AN, Turner KE, Wick V, Lawson S. Use of end-tidal PCO2 and transcutaneous PCO2 as noninvasive measurement of arterial PCO2 in extubated patients recovering from general anesthesia. J Clin Monit. 1992 Jul; 8(3):226-30. PMID: 1494929.
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    202. Kavanagh BP, Mazer CD, Panos A, Lichtenstein SV. Effect of warm heart surgery on perioperative management of patients undergoing urgent cardiac surgery. J Cardiothorac Vasc Anesth. 1992 Apr; 6(2):127-31. PMID: 1568000.
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    203. Kavanagh BP, Ryan MP, Cunningham AJ. Myocardial contractility and ischaemia in the isolated perfused rat heart with propofol and thiopentone. Can J Anaesth. 1991 Jul; 38(5):634-9. PMID: 1934218.
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