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Brenda Spiegler

TitleDirector of Psychology, Psychologist
InstitutionThe Hospital for Sick Children
DepartmentPsychology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tomlinson D, Baggott C, Dix D, Gibson P, Hyslop S, Johnston DL, Orsey A, Portwine C, Price V, Vanan M, Kuczynski S, Spiegler B, Tomlinson GA, Dupuis LL, Sung L. Severely bothersome fatigue in children and adolescents with cancer and hematopoietic stem cell transplant recipients. Support Care Cancer. 2018 Nov 26. PMID: 30478671.
      View in: PubMed
    2. Loves R, Tomlinson D, Baggott C, Dix D, Gibson P, Hyslop S, Johnston DL, Orsey AD, Portwine C, Price V, Schechter T, Vanan M, Kuczynski S, Spiegler B, Tomlinson GA, Dupuis LL, Sung L. Taste changes in children with cancer and hematopoietic stem cell transplant recipients. Support Care Cancer. 2018 Oct 15. PMID: 30324284.
      View in: PubMed
    3. Hyslop S, Sung L, Stein E, Dupuis LL, Spiegler B, Vettese E, Tomlinson D. Identifying symptoms using the drawings of 4-7 year olds with cancer. Eur J Oncol Nurs. 2018 Oct; 36:56-61. PMID: 30322510.
      View in: PubMed
    4. Spencer Noakes TL, Przybycien TS, Forwell A, Nicholls C, Zhou YQ, Butcher DT, Weksberg R, Guger SL, Spiegler BJ, Schachar RJ, Hitzler J, Ito S, van der Plas E, Nieman BJ. Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment. Clin Cancer Res. 2018 Dec 01; 24(23):6040-6052. PMID: 30054283.
      View in: PubMed
    5. Dupuis LL, Johnston DL, Baggott C, Hyslop S, Tomlinson D, Gibson P, Orsey A, Dix D, Price V, Vanan M, Portwine C, Kuczynski S, Spiegler B, Tomlinson GA, Sung L. Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments. J Natl Cancer Inst. 2018 Jun 01; 110(6):661-668. PMID: 29272441.
      View in: PubMed
    6. Hyslop S, Dupuis LL, Baggott C, Dix D, Gibson P, Kuczynski S, Johnston DL, Orsey A, Portwine C, Price V, Spiegler B, Tomlinson D, Vanan M, Tomlinson GA, Sung L. Validation of the Proxy Version of Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments. J Pain Symptom Manage. 2018 Jul; 56(1):107-112. PMID: 29630923.
      View in: PubMed
    7. Johnston DL, Hyslop S, Tomlinson D, Baggott C, Gibson P, Orsey A, Dix D, Price V, Vanan M, Portwine C, Kuczynski S, Spiegler B, Tomlinson GA, Dupuis LL, Sung L. Describing symptoms using the Symptom Screening in Pediatrics Tool in hospitalized children with cancer and hematopoietic stem cell transplant recipients. Cancer Med. 2018 May; 7(5):1750-1755. PMID: 29573197.
      View in: PubMed
    8. Van Der Plas E, Erdman L, Nieman BJ, Weksberg R, Butcher DT, O'connor DL, Aufreiter S, Hitzler J, Guger SL, Schachar RJ, Ito S, Spiegler BJ. Characterizing neurocognitive late effects in childhood leukemia survivors using a combination of neuropsychological and cognitive neuroscience measures. Child Neuropsychol. 2018 Nov; 24(8):999-1014. PMID: 29017430.
      View in: PubMed
    9. van der Plas E, Schachar RJ, Hitzler J, Crosbie J, Guger SL, Spiegler BJ, Ito S, Nieman BJ. Brain structure, working memory and response inhibition in childhood leukemia survivors. Brain Behav. 2017 02; 7(2):e00621. PMID: 28239531.
      View in: PubMed
    10. O'Sullivan C, Lee Dupuis L, Gibson P, Johnston DL, Baggott C, Portwine C, Spiegler B, Kuczynski S, Tomlinson D, Tomlinson GA, Sung L. Evaluation of the electronic self-report Symptom Screening in Pediatrics Tool (SSPedi). BMJ Support Palliat Care. 2018 Mar; 8(1):110-116. PMID: 27803061.
      View in: PubMed
    11. Janzen LA, David D, Walker D, Hitzler J, Zupanec S, Jones H, Spiegler BJ. Pre-Morbid Developmental Vulnerabilities in Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL). Pediatr Blood Cancer. 2015 Dec; 62(12):2183-8. PMID: 26305495.
      View in: PubMed
    12. Tomlinson D, de Mol Van Otterloo S, O'Sullivan C, Gibson P, Johnston DL, Portwine C, Spiegler B, Baggott C, Tolend M, Dupuis LL, Sung L. Methodological issues identified during cognitive interviews in the development of a pediatric cancer symptom screening tool. Psychooncology. 2016 Mar; 25(3):349-53. PMID: 25920596.
      View in: PubMed
    13. Roncadin C, Hitzler J, Downie A, Montour-Proulx I, Alyman C, Cairney E, Spiegler BJ. Neuropsychological late effects of treatment for acute leukemia in children with Down syndrome. Pediatr Blood Cancer. 2015 May; 62(5):854-8. PMID: 25545182.
      View in: PubMed
    14. O'Sullivan C, Dupuis LL, Gibson P, Johnston DL, Baggott C, Portwine C, Spiegler B, Kuczynski S, Tomlinson D, de Mol Van Otterloo S, Tomlinson GA, Sung L. Refinement of the symptom screening in pediatrics tool (SSPedi). Br J Cancer. 2014 Sep 23; 111(7):1262-8. PMID: 25101569; PMCID: PMC4183858.
    15. Dennis M, Spiegler BJ, Simic N, Sinopoli KJ, Wilkinson A, Yeates KO, Taylor HG, Bigler ED, Fletcher JM. Functional plasticity in childhood brain disorders: when, what, how, and whom to assess. Neuropsychol Rev. 2014 Dec; 24(4):389-408. PMID: 24821533; PMCID: PMC4231018.
    16. Moxon-Emre I, Bouffet E, Taylor MD, Laperriere N, Scantlebury N, Law N, Spiegler BJ, Malkin D, Janzen L, Mabbott D. Impact of craniospinal dose, boost volume, and neurologic complications on intellectual outcome in patients with medulloblastoma. J Clin Oncol. 2014 Jun 10; 32(17):1760-8. PMID: 24516024.
      View in: PubMed
    17. Dennis M, Spiegler BJ, Juranek JJ, Bigler ED, Snead OC, Fletcher JM. Age, plasticity, and homeostasis in childhood brain disorders. Neurosci Biobehav Rev. 2013 Dec; 37(10 Pt 2):2760-73. PMID: 24096190; PMCID: PMC3859812.
    18. Tomlinson D, Dupuis LL, Gibson P, Johnston DL, Portwine C, Baggott C, Zupanec S, Watson J, Spiegler B, Kuczynski S, Macartney G, Sung L. Initial development of the Symptom Screening in Pediatrics Tool (SSPedi). Support Care Cancer. 2014 Jan; 22(1):71-5. PMID: 23995756.
      View in: PubMed
    19. Edelstein K, D'agostino N, Bernstein LJ, Nathan PC, Greenberg ML, Hodgson DC, Millar BA, Laperriere N, Spiegler BJ. Long-term neurocognitive outcomes in young adult survivors of childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2011 Aug; 33(6):450-8. PMID: 21646917.
      View in: PubMed
    20. Mabbott DJ, Monsalves E, Spiegler BJ, Bartels U, Janzen L, Guger S, Laperriere N, Andrews N, Bouffet E. Longitudinal evaluation of neurocognitive function after treatment for central nervous system germ cell tumors in childhood. Cancer. 2011 Dec 01; 117(23):5402-11. PMID: 21563173.
      View in: PubMed
    21. Edelstein K, Spiegler BJ, Fung S, Panzarella T, Mabbott DJ, Jewitt N, D'Agostino NM, Mason WP, Bouffet E, Tabori U, Laperriere N, Hodgson DC. Early aging in adult survivors of childhood medulloblastoma: long-term neurocognitive, functional, and physical outcomes. Neuro Oncol. 2011 May; 13(5):536-45. PMID: 21367970; PMCID: PMC3093335.
    22. Dennis M, Salman MS, Jewell D, Hetherington R, Spiegler BJ, MacGregor DL, Drake JM, Humphreys RP, Gentili F. Upper limb motor function in young adults with spina bifida and hydrocephalus. Childs Nerv Syst. 2009 Nov; 25(11):1447-53. PMID: 19672605; PMCID: PMC3075008.
    23. Roncadin C, Dennis M, Greenberg ML, Spiegler BJ. Adverse medical events associated with childhood cerebellar astrocytomas and medulloblastomas: natural history and relation to very long-term neurobehavioral outcome. Childs Nerv Syst. 2008 Sep; 24(9):995-1002; discussion 1003. PMID: 18581121.
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    24. Boydell KM, Stasiulis E, Greenberg M, Greenberg C, Spiegler B. I'll show them: the social construction of (in)competence in survivors of childhood brain tumors. J Pediatr Oncol Nurs. 2008 May-Jun; 25(3):164-74. PMID: 18353751.
      View in: PubMed
    25. Janzen LA, Spiegler BJ. Neurodevelopmental sequelae of pediatric acute lymphoblastic leukemia and its treatment. Dev Disabil Res Rev. 2008; 14(3):185-95. PMID: 18924154.
      View in: PubMed
    26. Barrera M, Schulte F, Spiegler B. Factors influencing depressive symptoms of children treated for a brain tumor. J Psychosoc Oncol. 2008; 26(1):1-16. PMID: 18077259.
      View in: PubMed
    27. Huber JF, Bradley K, Spiegler B, Dennis M. Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival years. J Child Neurol. 2007 Jul; 22(7):848-54. PMID: 17715277.
      View in: PubMed
    28. Dennis M, Jewell D, Drake J, Misakyan T, Spiegler B, Hetherington R, Gentili F, Barnes M. Prospective, declarative, and nondeclarative memory in young adults with spina bifida. J Int Neuropsychol Soc. 2007 Mar; 13(2):312-23. PMID: 17286888.
      View in: PubMed
    29. Spiegler BJ, Kennedy K, Maze R, Greenberg ML, Weitzman S, Hitzler JK, Nathan PC. Comparison of long-term neurocognitive outcomes in young children with acute lymphoblastic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate. J Clin Oncol. 2006 Aug 20; 24(24):3858-64. PMID: 16921038.
      View in: PubMed
    30. Lafay-Cousin L, Millar BA, Mabbott D, Spiegler B, Drake J, Bartels U, Huang A, Bouffet E. Limited-field radiation for bifocal germinoma. Int J Radiat Oncol Biol Phys. 2006 Jun 01; 65(2):486-92. PMID: 16530340.
      View in: PubMed
    31. Huber JF, Bradley K, Spiegler BJ, Dennis M. Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood. Childs Nerv Syst. 2006 Feb; 22(2):132-8. PMID: 16155765.
      View in: PubMed
    32. Mabbott DJ, Spiegler BJ, Greenberg ML, Rutka JT, Hyder DJ, Bouffet E. Serial evaluation of academic and behavioral outcome after treatment with cranial radiation in childhood. J Clin Oncol. 2005 Apr 01; 23(10):2256-63. PMID: 15800316.
      View in: PubMed
    33. Spiegler BJ, Bouffet E, Greenberg ML, Rutka JT, Mabbott DJ. Change in neurocognitive functioning after treatment with cranial radiation in childhood. J Clin Oncol. 2004 Feb 15; 22(4):706-13. PMID: 14966095.
      View in: PubMed
    34. Nathan PC, Maze R, Spiegler B, Greenberg ML, Weitzman S, Hitzler JK. CNS-directed therapy in young children with T-lineage acute lymphoblastic leukemia: High-dose methotrexate versus cranial irradiation. Pediatr Blood Cancer. 2004 Jan; 42(1):24-9. PMID: 14752790.
      View in: PubMed
    35. Huber-Okrainec J, Dennis M, Brettschneider J, Spiegler BJ. Neuromotor speech deficits in children and adults with spina bifida and hydrocephalus. Brain Lang. 2002 Mar; 80(3):592-602. PMID: 11896659.
      View in: PubMed
    36. Hetherington R, Dennis M, Spiegler B. Perception and estimation of time in long-term survivors of childhood posterior fossa tumors. J Int Neuropsychol Soc. 2000 Sep; 6(6):682-92. PMID: 11011515.
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    37. Dennis M, Spiegler BJ, Hetherington R. New survivors for the new millennium: cognitive risk and reserve in adults with childhood brain insults. Brain Cogn. 2000 Feb; 42(1):102-5. PMID: 10739611.
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    38. Dennis M, Hetherington CR, Spiegler BJ. Memory and attention after childhood brain tumors. Med Pediatr Oncol. 1998; Suppl 1:25-33. PMID: 9659943.
      View in: PubMed
    39. Dennis M, Spiegler BJ, Hetherington CR, Greenberg ML. Neuropsychological sequelae of the treatment of children with medulloblastoma. J Neurooncol. 1996 Jul; 29(1):91-101. PMID: 8817420.
      View in: PubMed
    40. Dennis M, Spiegler BJ, Obonsawin MC, Maria BL, Cowell C, Hoffman HJ, Hendrick EB, Humphreys RP, Bailey JD, Ehrlich RM. Brain tumors in children and adolescents--III. Effects of radiation and hormone status on intelligence and on working, associative and serial-order memory. Neuropsychologia. 1992 Mar; 30(3):257-75. PMID: 1574161.
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    41. Dennis M, Spiegler BJ, Hoffman HJ, Hendrick EB, Humphreys RP, Becker LE. Brain tumors in children and adolescents--I. Effects on working, associative and serial-order memory of IQ, age at tumor onset and age of tumor. Neuropsychologia. 1991; 29(9):813-27. PMID: 1944880.
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    42. Dennis M, Spiegler BJ, Fitz CR, Hoffman HJ, Hendrick EB, Humphreys RP, Chuang S. Brain tumors in children and adolescents--II. The neuroanatomy of deficits in working, associative and serial-order memory. Neuropsychologia. 1991; 29(9):829-47. PMID: 1944881.
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    43. Reilly AN, Lutz MM, Spiegler B, Lynn P. Head trauma in children: the stages to cognitive recovery. MCN Am J Matern Child Nurs. 1987 Nov-Dec; 12(6):405-12. PMID: 3123844.
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    44. Salcedo JR, Spiegler BJ, Gibson E, Magilavy DB. The autoimmune disease systemic lupus erythematosus is not associated with left-handedness. Cortex. 1985 Dec; 21(4):645-7. PMID: 4092488.
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    45. Spiegler BJ, Yeni-Komshian GH. Incidence of left-handed writing in a college population with reference to family patterns of hand preference. Neuropsychologia. 1983; 21(6):651-9. PMID: 6664484.
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    46. Spiegler BJ, Mishkin M. Evidence for the sequential participation of inferior temporal cortex and amygdala in the acquisition of stimulus-reward associations. Behav Brain Res. 1981 Nov; 3(3):303-17. PMID: 7306385.
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