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Mark Friedberg

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentHeart Centre - Cardiology Div. Physicians Fellows & Secretaries
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bitterman Y, Hauck A, Manlhiot C, Reyes J, Dragulescu A, Mertens L, Friedberg MK. Serial Assessment of Tricuspid Annular Plane Systolic Excursion is Associated with Death or Lung Transplant in Children with Pulmonary Arterial Hypertension. J Am Soc Echocardiogr. 2021 Aug 27. PMID: 34461250.
      View in: PubMed
    2. Soveral I, Crispi F, Guirado L, García-Otero L, Torres X, Bennasar M, Sepúlveda-Martínez Á, Nogué L, Gratacós E, Martínez JM, Bijnens B, Friedberg M, Gómez O. Fetal cardiac filling and ejection time fractions by pulsed-wave Doppler: reference ranges and potential clinical application. Ultrasound Obstet Gynecol. 2021 07; 58(1):83-91. PMID: 32672395.
      View in: PubMed
    3. Akazawa Y, Fujioka T, Ide H, Yazaki K, Honjo O, Sun M, Friedberg MK. Impaired right and left ventricular function and relaxation induced by pulmonary regurgitation are not reversed by tardive antifibrosis treatment. Am J Physiol Heart Circ Physiol. 2021 07 01; 321(1):H38-H51. PMID: 34048283.
      View in: PubMed
    4. Meagher PB, Lee XA, Lee J, Visram A, Friedberg MK, Connelly KA. Cardiac Fibrosis: Key Role of Integrins in Cardiac Homeostasis and Remodeling. Cells. 2021 03 31; 10(4). PMID: 33807373.
      View in: PubMed
    5. Fraser AG, Bijnens BH, Friedberg MK. Understanding right ventricular dyssynchrony: Its myriad determinants and clinical relevance. Exp Physiol. 2021 Apr; 106(4):797-800. PMID: 33599973.
      View in: PubMed
    6. Friedberg MK. Peeking Beyond Strain's Peak: Regional Strain Patterns and Dispersion in Arrhythmogenic Right Ventricular Cardiomyopathy. JACC Cardiovasc Imaging. 2021 05; 14(5):911-914. PMID: 33582065.
      View in: PubMed
    7. Traister A, Patel R, Huang A, Patel S, Plakhotnik J, Lee JE, Medina MG, Welsh C, Ruparel P, Zhang L, Friedberg M, Maynes J, Coles J. Correction: Cardiac regenerative capacity is age- and disease-dependent in childhood heart disease. PLoS One. 2021; 16(1):e0245808. PMID: 33471867.
      View in: PubMed
    8. Ebata R, Fujioka T, Diab SG, Pieles G, Ishii R, Ide H, Sun M, Slorach C, Liu K, Honjo O, Stortz G, Friedberg MK. Asymmetric Regional Work Contributes to Right Ventricular Fibrosis, Inefficiency, and Dysfunction in Pulmonary Hypertension versus Regurgitation. J Am Soc Echocardiogr. 2021 May; 34(5):537-550.e3. PMID: 33383122.
      View in: PubMed
    9. Ishii R, Steve Fan CP, Mertens L, Manlhiot C, Friedberg MK. Longitudinal Prediction of Transplant-Free Survival by Echocardiography in Pediatric Dilated Cardiomyopathy. Can J Cardiol. 2021 Jun; 37(6):867-876. PMID: 33347978.
      View in: PubMed
    10. Ishii R, Okumura K, Akazawa Y, Malhi M, Ebata R, Sun M, Fujioka T, Kato H, Honjo O, Kabir G, Kuebler WM, Connelly K, Maynes JT, Friedberg MK. Heart Rate Reduction Improves Right Ventricular Function and Fibrosis in Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2020 12; 63(6):843-855. PMID: 32915674.
      View in: PubMed
    11. Haller C, Friedberg MK, Laflamme MA. The role of regenerative therapy in the treatment of right ventricular failure: a literature review. Stem Cell Res Ther. 2020 11 25; 11(1):502. PMID: 33239066.
      View in: PubMed
    12. Villemain O, Baranger J, Jalal Z, Lam C, Calais J, Pernot M, Cifra B, Friedberg MK, Mertens L. Non-invasive imaging techniques to assess myocardial perfusion. Expert Rev Med Devices. 2020 Nov; 17(11):1133-1144. PMID: 33044100.
      View in: PubMed
    13. Akazawa Y, Okumura K, Ishii R, Slorach C, Hui W, Ide H, Honjo O, Sun M, Kabir G, Connelly K, Friedberg MK. Pulmonary artery banding is a relevant model to study the right ventricular remodeling and dysfunction that occurs in pulmonary arterial hypertension. J Appl Physiol (1985). 2020 08 01; 129(2):238-246. PMID: 32644912.
      View in: PubMed
    14. Hui W, Slorach C, Iori S, Dragulescu A, Mertens L, Friedberg MK. The right ventricular myocardial systolic-to-diastolic duration ratio in children after surgical repair of Tetralogy of Fallot. J Appl Physiol (1985). 2020 06 01; 128(6):1677-1683. PMID: 32437247.
      View in: PubMed
    15. Burkett DA, Patel SS, Mertens L, Friedberg MK, Ivy DD. Relationship Between Left Ventricular Geometry and Invasive Hemodynamics in Pediatric Pulmonary Hypertension. Circ Cardiovasc Imaging. 2020 05; 13(5):e009825. PMID: 32408829.
      View in: PubMed
    16. Pieles GE, Alkon J, Manlhiot C, Fan CS, Kinnear C, Benson LN, Mital S, Friedberg MK. Association between genetic variants in the HIF1A-VEGF pathway and left ventricular regional myocardial deformation in patients with hypertrophic cardiomyopathy. Pediatr Res. 2021 02; 89(3):628-635. PMID: 32375165.
      View in: PubMed
    17. Gold J, Akazawa Y, Sun M, Hunter KS, Friedberg MK. Relation between right ventricular wall stress, fibrosis, and function in right ventricular pressure loading. . 2020 02 01; 318(2):H366-H377. PMID: 31886720.
      View in: PubMed
    18. Slieker MG, Fackoury C, Slorach C, Hui W, Friedberg MK, Fan CS, Manlhiot C, Dillenburg R, Kantor P, Mital S, Liu P, Nathan PC, Mertens L. Echocardiographic Assessment of Cardiac Function in Pediatric Survivors of Anthracycline-Treated Childhood Cancer. Circ Cardiovasc Imaging. 2019 12; 12(12):e008869. PMID: 31826678.
      View in: PubMed
    19. Guirado L, Crispi F, Soveral I, Valenzuela-Alcaraz B, Rodriguez-López M, García-Otero L, Torres X, Sepúlveda-Martínez Á, Escobar-Diaz MC, Martínez JM, Friedberg MK, Gratacós E, Gómez O. Nomograms of Fetal Right Ventricular Fractional Area Change by 2D Echocardiography. Fetal Diagn Ther. 2020; 47(5):399-410. PMID: 31822009.
      View in: PubMed
    20. Di Maria MV, Campbell KR, Burkett DA, Younoszai AK, Landeck BF, Mertens L, Ivy DD, Hunter KS, Friedberg MK. Parameters of Right Ventricular Function Reveal Ventricular-Vascular Mismatch as Determined by Right Ventricular Stroke Work versus Pulmonary Vascular Resistance in Children with Pulmonary Hypertension. J Am Soc Echocardiogr. 2020 02; 33(2):218-225. PMID: 31836268.
      View in: PubMed
    21. Kobayashi J, Luo S, Akazawa Y, Parker M, Wang J, Chiasson D, Friedberg MK, Haller C, Honjo O. Flow-targeted pediatric ex vivo heart perfusion in donation after circulatory death: A porcine model. J Heart Lung Transplant. 2020 03; 39(3):267-277. PMID: 31892427.
      View in: PubMed
    22. Villemain O, Baranger J, Friedberg MK, Papadacci C, Dizeux A, Messas E, Tanter M, Pernot M, Mertens L. Ultrafast Ultrasound Imaging in Pediatric and Adult Cardiology: Techniques, Applications, and Perspectives. JACC Cardiovasc Imaging. 2020 08; 13(8):1771-1791. PMID: 31734211.
      View in: PubMed
    23. Goudar SP, Zak V, Atz AM, Altmann K, Colan SD, Falkensammer CB, Friedberg MK, Frommelt M, Hill KD, Hsu DT, Levine JC, Margossian R, Mart CR, Sticka J, Shrader P, Shirali G. Comparison of echocardiographic measurements to invasive measurements of diastolic function in infants with single ventricle physiology: a report from the Pediatric Heart Network Infant Single Ventricle Trial. Cardiol Young. 2019 Oct; 29(10):1248-1256. PMID: 31477187.
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    24. Friedberg MK, Reddy S. Right ventricular failure in congenital heart disease. Curr Opin Pediatr. 2019 10; 31(5):604-610. PMID: 31356354.
      View in: PubMed
    25. Forsha D, Li L, Joseph N, Kutty S, Friedberg MK. Association of left ventricular size with regional right ventricular mechanics in Hypoplastic Left Heart Syndrome. Int J Cardiol. 2020 01 01; 298:66-71. PMID: 31402159.
      View in: PubMed
    26. Rösner A, Bharucha T, James A, Mertens L, Friedberg MK. Impact of Right Ventricular Geometry and Left Ventricular Hypertrophy on Right Ventricular Mechanics and Clinical Outcomes in Hypoplastic Left Heart Syndrome. J Am Soc Echocardiogr. 2019 10; 32(10):1350-1358. PMID: 31351794.
      View in: PubMed
    27. Akazawa Y, Fujioka T, Kühn A, Hui W, Slorach C, Roehlig C, Mertens L, Vogt M, Friedberg MK. Right Ventricular Diastolic Function and Right Atrial Function and Their Relation With Exercise Capacity in Ebstein Anomaly. Can J Cardiol. 2019 Dec; 35(12):1824-1833. PMID: 31564390.
      View in: PubMed
    28. Friedberg MK, Dragulescu A. Serial Assessment of Right Ventricular Strain in Hypoplastic Left Heart Syndrome: Deformation Imaging in Deformed Hearts. J Am Soc Echocardiogr. 2019 05; 32(5):651-654. PMID: 31056093.
      View in: PubMed
    29. Larios G, Yim D, Dragulescu A, Mertens L, Grosse-Wortmann L, Friedberg MK. Right ventricular function in patients with pulmonary regurgitation with versus without tetralogy of Fallot. Am Heart J. 2019 07; 213:8-17. PMID: 31071505.
      View in: PubMed
    30. Pieles GE, Grosse-Wortmann L, Hader M, Fatah M, Chungsomprasong P, Slorach C, Hui W, Fan CS, Manlhiot C, Mertens L, Hamilton R, Friedberg MK. Association of Echocardiographic Parameters of Right Ventricular Remodeling and Myocardial Performance With Modified Task Force Criteria in Adolescents With Arrhythmogenic Right Ventricular Cardiomyopathy. Circ Cardiovasc Imaging. 2019 04; 12(4):e007693. PMID: 31002275.
      View in: PubMed
    31. Lumens J, Fan CS, Walmsley J, Yim D, Manlhiot C, Dragulescu A, Grosse-Wortmann L, Mertens L, Prinzen FW, Delhaas T, Friedberg MK. Relative Impact of Right Ventricular Electromechanical Dyssynchrony Versus Pulmonary Regurgitation on Right Ventricular Dysfunction and Exercise Intolerance in Patients After Repair of Tetralogy of Fallot. J Am Heart Assoc. 2019 01 22; 8(2):e010903. PMID: 30651018.
      View in: PubMed
    32. Morgan CT, Mueller B, Thakur V, Guerra V, Jull C, Mertens L, Friedberg M, Golding F, Seed M, Miner SES, Jaeggi ET, Manlhiot C, Nield LE. Improving Prenatal Diagnosis of Coarctation of the Aorta. Can J Cardiol. 2019 04; 35(4):453-461. PMID: 30935636.
      View in: PubMed
    33. Fujioka T, Kühn A, Sanchez-Martinez S, Bijnens BH, Hui W, Slorach C, Roehlig C, Mertens L, Vogt M, Friedberg MK. Impact of Interventricular Interactions on Left Ventricular Function, Stroke Volume, and Exercise Capacity in Children and Adults With Ebstein's Anomaly. JACC Cardiovasc Imaging. 2019 May; 12(5):925-927. PMID: 30553666.
      View in: PubMed
    34. Yamamura K, Yuen D, Hickey EJ, He X, Chaturvedi RR, Friedberg MK, Grosse-Wortmann L, Hanneman K, Billia F, Farkouh ME, Wald RM. Right ventricular fibrosis is associated with cardiac remodelling after pulmonary valve replacement. Heart. 2019 06; 105(11):855-863. PMID: 30514732.
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    35. Grotenhuis HB, Dallaire F, Verpalen IM, van den Akker MJE, Mertens L, Friedberg MK. Aortic Root Dilatation and Aortic-Related Complications in Children After Tetralogy of Fallot Repair. Circ Cardiovasc Imaging. 2018 12; 11(12):e007611. PMID: 30562107.
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    36. Driessen MMP, Leiner T, Sieswerda GT, van Dijk APJ, Post MC, Friedberg MK, Mertens L, Doevendans PA, Snijder RJ, Hulzebos EH, Meijboom FJ. RV adaptation to increased afterload in congenital heart disease and pulmonary hypertension. PLoS One. 2018; 13(10):e0205196. PMID: 30356250.
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    37. Rösner A, Khalapyan T, Pedrosa J, Dalen H, McElhinney DB, Friedberg MK, Lui GK. Ventricular mechanics in adolescent and adult patients with a Fontan circulation: Relation to geometry and wall stress. Echocardiography. 2018 12; 35(12):2035-2046. PMID: 30350438.
      View in: PubMed
    38. Lopez C, Mertens L, Dragulescu A, Landeck B, Younoszai A, Friedberg MK, Hunter K, Di Maria MV. Strain and Rotational Mechanics in Children With Single Left Ventricles After Fontan. J Am Soc Echocardiogr. 2018 12; 31(12):1297-1306. PMID: 30344011.
      View in: PubMed
    39. Grattan M, Mertens L, Grosse-Wortmann L, Friedberg MK, Cifra B, Dragulescu A. Ventricular Torsion in Young Patients With Single-Ventricle Anatomy. J Am Soc Echocardiogr. 2018 12; 31(12):1288-1296. PMID: 30340887.
      View in: PubMed
    40. Traister A, Patel R, Huang A, Patel S, Plakhotnik J, Lee JE, Medina MG, Welsh C, Ruparel P, Zhang L, Friedberg M, Maynes J, Coles J. Cardiac regenerative capacity is age- and disease-dependent in childhood heart disease. PLoS One. 2018; 13(7):e0200342. PMID: 30044800.
      View in: PubMed
    41. Yim D, Hui W, Larios G, Dragulescu A, Grosse-Wortmann L, Bijnens B, Mertens L, Friedberg MK. Quantification of Right Ventricular Electromechanical Dyssynchrony in Relation to Right Ventricular Function and Clinical Outcomes in Children with Repaired Tetralogy of Fallot. J Am Soc Echocardiogr. 2018 07; 31(7):822-830. PMID: 29976349.
      View in: PubMed
    42. Son JS, James A, Fan CS, Mertens L, McCrindle BW, Manlhiot C, Friedberg MK. Prognostic Value of Serial Echocardiography in Hypoplastic Left Heart Syndrome. Circ Cardiovasc Imaging. 2018 07; 11(7):e006983. PMID: 30012823.
      View in: PubMed
    43. Cifra B, Morgan CT, Dragulescu A, Guerra VC, Slorach C, Friedberg MK, Manlhiot C, McCrindle BW, Dipchand AI, Mertens L. Right ventricular function during exercise in children after heart transplantation. Eur Heart J Cardiovasc Imaging. 2018 06 01; 19(6):647-653. PMID: 28655190.
      View in: PubMed
    44. Friedberg MK. Imaging Right-Left Ventricular Interactions. JACC Cardiovasc Imaging. 2018 05; 11(5):755-771. PMID: 29747850.
      View in: PubMed
    45. Roldan Ramos S, Pieles G, Hui W, Slorach C, Redington AN, Friedberg MK. A rabbit model of progressive chronic right ventricular pressure overload. Interact Cardiovasc Thorac Surg. 2018 04 01; 26(4):673-680. PMID: 29211855.
      View in: PubMed
    46. Cifra B, Chen CK, Fan CS, Slorach C, Manlhiot C, McCrindle BW, Dragulescu A, Redington AN, Friedberg MK, Nathan PC, Mertens L. Dynamic Myocardial Response to Exercise in Childhood Cancer Survivors Treated with Anthracyclines. J Am Soc Echocardiogr. 2018 08; 31(8):933-942. PMID: 29615292.
      View in: PubMed
    47. Sun M, Ishii R, Okumura K, Krauszman A, Breitling S, Gomez O, Hinek A, Boo S, Hinz B, Connelly KA, Kuebler WM, Friedberg MK. Experimental Right Ventricular Hypertension Induces Regional ß1-Integrin-Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling. J Am Heart Assoc. 2018 03 29; 7(7). PMID: 29599211.
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    48. Hui W, Slorach C, Friedberg MK. Apical Transverse Motion Is Associated with Interventricular Mechanical Delay and Decreased Left Ventricular Function in Children with Dilated Cardiomyopathy. J Am Soc Echocardiogr. 2018 08; 31(8):943-950. PMID: 29606334.
      View in: PubMed
    49. Friedberg MK. Longitudinal Doppler Assessment of Congenital Aortic Stenosis: It Is About Time! Circ Cardiovasc Imaging. 2018 03; 11(3):e007622. PMID: 29555839.
      View in: PubMed
    50. Guirado L, Crispi F, Masoller N, Bennasar M, Marimon E, Carretero J, Gratacós E, Martínez JM, Friedberg MK, Gómez O. Biventricular impact of mild to moderate fetal pulmonary valve stenosis. Ultrasound Obstet Gynecol. 2018 Mar; 51(3):349-356. PMID: 28295792.
      View in: PubMed
    51. Ramos SR, Pieles G, Sun M, Slorach C, Hui W, Friedberg MK. Early versus late cardiac remodeling during right ventricular pressure load and impact of preventive versus rescue therapy with endothelin-1 receptor blockers. J Appl Physiol (1985). 2018 05 01; 124(5):1349-1362. PMID: 29446710.
      View in: PubMed
    52. Kuebler WM, Friedberg MK. Letter by Kuebler and Friedberg Regarding Article, "Pulmonary Artery Denervation by Determining Targeted Ablation Sites for Treatment of Pulmonary Arterial Hypertension". Circ Cardiovasc Interv. 2018 02; 11(2):e006148. PMID: 29371213.
      View in: PubMed
    53. Rösner A, Khalapyan T, Dalen H, McElhinney DB, Friedberg MK, Lui GK. Classic-Pattern Dyssynchrony in Adolescents and Adults With a Fontan Circulation. J Am Soc Echocardiogr. 2018 02; 31(2):211-219. PMID: 29229494.
      View in: PubMed
    54. Gomez O, Okumura K, Honjo O, Sun M, Ishii R, Bijnens B, Friedberg MK. Heart rate reduction improves biventricular function and interactions in experimental pulmonary hypertension. . 2018 03 01; 314(3):H542-H551. PMID: 29146614.
      View in: PubMed
    55. Friedberg MK. Another Step in the Right Direction: Resynchronizing the Dyssynchronous Right Ventricle Improves Its Efficiency and Function. Circ Cardiovasc Imaging. 2017 09; 10(9). PMID: 28877887.
      View in: PubMed
    56. Larios G, Friedberg MK. Imaging in repaired tetralogy of Fallot with a focus on recent advances in echocardiography. Curr Opin Cardiol. 2017 Sep; 32(5):490-502. PMID: 28639972.
      View in: PubMed
    57. Ramos SR, Pieles G, Hui W, Ishii R, Slorach C, Friedberg MK. Comprehensive echocardiographic assessment of biventricular function in the rabbit, animal model in cardiovascular research: feasibility and normal values. Int J Cardiovasc Imaging. 2018 Mar; 34(3):367-375. PMID: 28840383.
      View in: PubMed
    58. Nielsen EA, Okumura K, Sun M, Hjortdal VE, Redington AN, Friedberg MK. Regional septal hinge-point injury contributes to adverse biventricular interactions in pulmonary hypertension. Physiol Rep. 2017 Jul; 5(14). PMID: 28733311.
      View in: PubMed
    59. Timbie JW, Setodji CM, Kress A, Lavelle TA, Friedberg MW, Mendel PJ, Chen EK, Weidmer BA, Buttorff C, Malsberger R, Kommareddi M, Rastegar A, Kofner A, Hiatt L, Mahmud A, Giuriceo K, Kahn KL. Implementation of Medical Homes in Federally Qualified Health Centers. N Engl J Med. 2017 07 20; 377(3):246-256. PMID: 28636834.
      View in: PubMed
    60. Driessen MMP, Meijboom FJ, Hui W, Dragulescu A, Mertens L, Friedberg MK. Regional right ventricular remodeling and function in children with idiopathic pulmonary arterial hypertension vs those with pulmonary valve stenosis: Insights into mechanics of right ventricular dysfunction. Echocardiography. 2017 Jun; 34(6):888-897. PMID: 28370259.
      View in: PubMed
    61. Mawad W, Friedberg MK. The continuing challenge of evaluating diastolic function by echocardiography in children: developing concepts and newer modalities. Curr Opin Cardiol. 2017 01; 32(1):93-100. PMID: 27898434.
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    62. Yim D, Mertens L, Morgan CT, Friedberg MK, Grosse-Wortmann L, Dragulescu A. Impact of surgical pulmonary valve replacement on ventricular mechanics in children with repaired tetralogy of Fallot. Int J Cardiovasc Imaging. 2017 May; 33(5):711-720. PMID: 28005218.
      View in: PubMed
    63. Simpson J, Lopez L, Acar P, Friedberg MK, Khoo NS, Ko HH, Marek J, Marx G, McGhie JS, Meijboom F, Roberson D, Van den Bosch A, Miller O, Shirali G. Three-dimensional Echocardiography in Congenital Heart Disease: An Expert Consensus Document from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017 01; 30(1):1-27. PMID: 27838227.
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    64. Simpson J, Lopez L, Acar P, Friedberg M, Khoo N, Ko H, Marek J, Marx G, McGhie J, Meijboom F, Roberson D, Van den Bosch A, Miller O, Shirali G. Three-dimensional echocardiography in congenital heart disease: an expert consensus document from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. Eur Heart J Cardiovasc Imaging. 2016 Oct; 17(10):1071-97. PMID: 27655864.
      View in: PubMed
    65. Ban KA, Cohen ME, Ko CY, Friedberg MW, Stulberg JJ, Zhou L, Hall BL, Hoyt DB, Bilimoria KY. Evaluation of the ProPublica Surgeon Scorecard "Adjusted Complication Rate" Measure Specifications. Ann Surg. 2016 10; 264(4):566-74. PMID: 27433895.
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    66. Friedberg MK, Schwartz SM, Zhang H, Chiu-Man C, Manlhiot C, Ilina MV, Arsdell GV, Kirsh JA, McCrindle BW, Stephenson EA. Hemodynamic effects of sustained postoperative cardiac resynchronization therapy in infants after repair of congenital heart disease: Results of a randomized clinical trial. Heart Rhythm. 2017 02; 14(2):240-247. PMID: 27687644.
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    67. Chowdhury SM, Goudar SP, Baker GH, Taylor CL, Shirali GS, Friedberg MK, Dragulescu A, Chessa KS, Mertens L. Speckle-Tracking Echocardiographic Measures of Right Ventricular Diastolic Function Correlate with Reference Standard Measures Before and After Preload Alteration in Children. Pediatr Cardiol. 2017 Jan; 38(1):27-35. PMID: 27655413.
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    68. Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Impact of Pulmonary Hemodynamics and Ventricular Interdependence on Left Ventricular Diastolic Function in Children With Pulmonary Hypertension. Circ Cardiovasc Imaging. 2016 Sep; 9(9). PMID: 27581953.
      View in: PubMed
    69. Friedberg MK. Echocardiographic Detection of Heart Transplant Graft Dysfunction: A New Twist on an Old Theme. Circ Cardiovasc Imaging. 2016 09; 9(9). PMID: 27609821.
      View in: PubMed
    70. Tretter JT, Friedberg MK, Wald RM, McElhinney DB. Defining and refining indications for transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot: Contributions from anatomical and functional imaging. Int J Cardiol. 2016 Oct 15; 221:916-25. PMID: 27441469.
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    71. Shahian DM, Normand SL, Friedberg MW, Hutter MM, Pronovost PJ. Rating the Raters: The Inconsistent Quality of Health Care Performance Measurement. Ann Surg. 2016 07; 264(1):36-8. PMID: 26756770.
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    72. Driessen MM, Hui W, Bijnens BH, Dragulescu A, Mertens L, Meijboom FJ, Friedberg MK. Adverse ventricular-ventricular interactions in right ventricular pressure load: Insights from pediatric pulmonary hypertension versus pulmonary stenosis. Physiol Rep. 2016 Jun; 4(11). PMID: 27302992.
      View in: PubMed
    73. Dallaire F, Slorach C, Bradley T, Hui W, Sarkola T, Friedberg MK, Jaeggi E, Dragulescu A, Mahmud FH, Daneman D, Mertens L. Pediatric Reference Values and Z Score Equations for Left Ventricular Systolic Strain Measured by Two-Dimensional Speckle-Tracking Echocardiography. J Am Soc Echocardiogr. 2016 08; 29(8):786-793.e8. PMID: 27185223.
      View in: PubMed
    74. Cifra B, Mertens L, Mirkhani M, Slorach C, Hui W, Manlhiot C, Friedberg MK, Dragulescu A. Systolic and Diastolic Myocardial Response to Exercise in a Healthy Pediatric Cohort. J Am Soc Echocardiogr. 2016 07; 29(7):648-54. PMID: 27038512.
      View in: PubMed
    75. Schantz D, Benson L, Windram J, Wong D, Dragulescu A, Yoo SJ, Mertens L, Friedberg M, Al Nafisi B, Grosse-Wortmann L. Abnormal Mitral Valve Dimensions in Pediatric Patients with Hypertrophic Cardiomyopathy. Pediatr Cardiol. 2016 Apr; 37(4):784-8. PMID: 26961572.
      View in: PubMed
    76. Friedberg MK, Margossian R, Lu M, Mercer-Rosa L, Henderson HT, Nutting A, Friedman K, Molina KM, Altmann K, Canter C, Sleeper LA, Colan SD. Systolic-diastolic functional coupling in healthy children and in those with dilated cardiomyopathy. J Appl Physiol (1985). 2016 Jun 01; 120(11):1301-18. PMID: 26940654.
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    77. Koestenberger M, Friedberg MK, Nestaas E, Michel-Behnke I, Hansmann G. Transthoracic echocardiography in the evaluation of pediatric pulmonary hypertension and ventricular dysfunction. Pulm Circ. 2016 Mar; 6(1):15-29. PMID: 27162612.
      View in: PubMed
    78. Grotenhuis HB, Ruijsink B, Chetan D, Dragulescu A, Friedberg MK, Kotani Y, Caldarone CA, Honjo O, Mertens LL. Impact of Norwood versus hybrid palliation on cardiac size and function in hypoplastic left heart syndrome. Heart. 2016 06 15; 102(12):966-74. PMID: 26908097.
      View in: PubMed
    79. Nielsen EA, Sun M, Honjo O, Hjortdal VE, Redington AN, Friedberg MK. Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload. PLoS One. 2016; 11(1):e0146767. PMID: 26765263.
      View in: PubMed
    80. Li J, Cai S, Peng J, Friedberg MK, Redington AN. Time Dependent Distribution of MicroRNA 144 after Intravenous Delivery. Microrna. 2016; 5(1):36-49. PMID: 27001183.
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    81. Forsha D, Slorach C, Chen CK, Sherman A, Mertens L, Barker P, Kisslo J, Friedberg MK. Patterns of Mechanical Inefficiency in Pediatric Dilated Cardiomyopathy and Their Relation to Left Ventricular Function and Clinical Outcomes. J Am Soc Echocardiogr. 2016 Mar; 29(3):226-36. PMID: 26711366.
      View in: PubMed
    82. Breitling S, Krauszman A, Parihar R, Walther T, Friedberg MK, Kuebler WM. Dose-dependent, therapeutic potential of angiotensin-(1-7) for the treatment of pulmonary arterial hypertension. Pulm Circ. 2015 Dec; 5(4):649-57. PMID: 26697172.
      View in: PubMed
    83. Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. PMID: 26534956.
      View in: PubMed
    84. Di Maria MV, Burkett DA, Younoszai AK, Landeck BF, Mertens L, Ivy DD, Friedberg MK, Hunter KS. Echocardiographic estimation of right ventricular stroke work in children with pulmonary arterial hypertension: comparison with invasive measurements. J Am Soc Echocardiogr. 2015 Nov; 28(11):1350-7. PMID: 26299333.
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    180. Friedberg MK, Silverman NH. Changing indications for fetal echocardiography in a University Center population. Prenat Diagn. 2004 Oct; 24(10):781-6. PMID: 15503290.
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    181. Friedberg M, Khoury A, Schwartz Y, Braver Y, Lorber A. Percutaneous transcatheter occlusion of the patent arterial duct using the pfm DuctOcclud Coil via a trans-aortic and trans-pulmonary approach. Cardiol Young. 2002 Oct; 12(5):465-9. PMID: 15773450.
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    182. Frohnert PP, Giuliani ER, Friedberg M, Johnson WJ, Tauxe WN. Statistical investigation of correlations between serum potassium levels and electrocardiographic findings in patients on intermittent hemodialysis therapy. Circulation. 1970 Apr; 41(4):667-76. PMID: 5437411.
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