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Cecil Hahn

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentNeurology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
ORCID ORCID Icon0000-0002-0887-876 Additional info
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    Collapse Biography 
    Collapse education and training
    Amherst College, Amherst, MAA.B.05/1994Neuroscience
    University of Toronto, Toronto, ONM.D. 06/1998Medicine
    Harvard University, Boston, MAM.P.H.06/2006Clinical Effectiveness

    Collapse Overview 
    Collapse overview
    Dr. Hahn is principal investigator of a multi-centre prospective study of seizures among comatose critically ill children, with goals to measure the prevalence of seizures, characterize patients at risk for seizures, and measure the impact of these seizures on functional and neuropsychological outcomes.

    His research group also continues to investigate the utility of quantitative EEG trending displays to assist with seizure identification among critically ill infants and children.

    In addition, Dr. Hahn has held leadership roles in an international research consortium on critical care EEG monitoring, through which he and his group are contributing to several collaborative multi-center studies.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Pittet MP, Marini D, Ly L, Au-Young SH, Chau V, Seed M, Miller SP, Hahn CD. Prevalence, Risk Factors, and Impact of Preoperative Seizures in Neonates With Congenital Heart Disease. J Clin Neurophysiol. 2021 Feb 04. PMID: 33560701.
      View in: PubMed
    2. McKenzie KC, Hahn CD, Friedman JN. Emergency management of the paediatric patient with convulsive status epilepticus. Paediatr Child Health. 2021 Feb; 26(1):50-66. PMID: 33552322.
      View in: PubMed
    3. Hirsch LJ, Fong MWK, Leitinger M, LaRoche SM, Beniczky S, Abend NS, Lee JW, Wusthoff CJ, Hahn CD, Westover MB, Gerard EE, Herman ST, Haider HA, Osman G, Rodriguez-Ruiz A, Maciel CB, Gilmore EJ, Fernandez A, Rosenthal ES, Claassen J, Husain AM, Yoo JY, So EL, Kaplan PW, Nuwer MR, van Putten M, Sutter R, Drislane FW, Trinka E, Gaspard N. American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version. J Clin Neurophysiol. 2021 Jan 01; 38(1):1-29. PMID: 33475321.
      View in: PubMed
    4. Akiyama A, Tsai JD, W Y Tam E, Kamino D, Hahn C, Go CY, Chau V, Whyte H, Wilson D, McNair C, Papaioannou V, Hugh SC, Papsin BC, Nishijima S, Yamazaki T, Miller SP, Ochi A. The Effect of Music and White Noise on Electroencephalographic (EEG) Functional Connectivity in Neonates in the Neonatal Intensive Care Unit. J Child Neurol. 2021 Jan; 36(1):38-47. PMID: 32838628.
      View in: PubMed
    5. Deshpande P, Jain A, Ibarra Ríos D, Bhattacharya S, Dirks J, Baczynski M, McNamara KP, Hahn C, McNamara PJ, Shah P, Guerguerian AM. Combined Multimodal Cerebral Monitoring and Focused Hemodynamic Assessment in the First 72 h in Extremely Low Gestational Age Infants. Neonatology. 2020; 117(4):504-512. PMID: 32814317.
      View in: PubMed
    6. Taran S, Ahmed W, Bui E, Prisco L, Hahn CD, McCredie VA. Educational initiatives and implementation of electroencephalography into the acute care environment: a protocol of a systematic review. Syst Rev. 2020 08 10; 9(1):175. PMID: 32778151.
      View in: PubMed
    7. Lewis H, Samanta D, Örsell JL, Bosanko KA, Rowell A, Jones M, Dale RC, Taravath S, Hahn CD, Krishnakumar D, Chagnon S, Keller S, Hagebeuk E, Pathak S, Bebin EM, Arndt DH, Alexander JJ, Mainali G, Coppola G, Maclean J, Sparagana S, McNamara N, Smith DM, Raggio V, Cruz M, Fernández-Jaén A, Kava MP, Emrick L, Fish JL, Vanderver A, Helman G, Pierson TM, Zarate YA. Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome. Pediatr Neurol. 2020 11; 112:94-100. PMID: 32446642.
      View in: PubMed
    8. Din F, Lalgudi Ganesan S, Akiyama T, Stewart CP, Ochi A, Otsubo H, Go C, Hahn CD. Seizure Detection Algorithms in Critically Ill Children: A Comparative Evaluation. Crit Care Med. 2020 04; 48(4):545-552. PMID: 32205601.
      View in: PubMed
    9. Grass B, Crosdale B, Keyzers M, Deshpande P, Hahn C, Ly LG, McNamara PJ. Implementation of amplitude-integrated electroencephalography in tertiary Canadian Neonatal Intensive Care Units-a longitudinal study. Paediatr Child Health. 2020 Dec; 25(8):511-517. PMID: 33354260.
      View in: PubMed
    10. Lalgudi Ganesan S, Hahn CD. Electrographic seizure burden and outcomes following pediatric status epilepticus. Epilepsy Behav. 2019 12; 101(Pt B):106409. PMID: 31420288.
      View in: PubMed
    11. Buttle SG, Sell E, Webster R, Varin M, Lemyre B, Hahn C, Pohl D. Continuous Electroencephalography Monitoring for Critically Ill Neonates: A Canadian Perspective. Can J Neurol Sci. 2019 07; 46(4):394-402. PMID: 31030685.
      View in: PubMed
    12. Pinchefsky EF, Hahn CD, Kamino D, Chau V, Brant R, Moore AM, Tam EWY. Hyperglycemia and Glucose Variability Are Associated with Worse Brain Function and Seizures in Neonatal Encephalopathy: A Prospective Cohort Study. J Pediatr. 2019 06; 209:23-32. PMID: 30982528.
      View in: PubMed
    13. Lalgudi Ganesan S, Stewart CP, Atenafu EG, Sharma R, Guerguerian AM, Hutchison JS, Hahn CD. Seizure Identification by Critical Care Providers Using Quantitative Electroencephalography. Crit Care Med. 2018 12; 46(12):e1105-e1111. PMID: 30188384.
      View in: PubMed
    14. Amorim E, Gilmore EJ, Abend NS, Hahn CD, Gaspard N, Herman ST, Hirsch LJ, Lee JW, Cash SS, Westover MB. EEG Reactivity Evaluation Practices for Adult and Pediatric Hypoxic-Ischemic Coma Prognostication in North America. J Clin Neurophysiol. 2018 Nov; 35(6):510-514. PMID: 30216207.
      View in: PubMed
    15. Sansevere AJ, Hahn CD, Abend NS. Conventional and quantitative EEG in status epilepticus. Seizure. 2019 May; 68:38-45. PMID: 30528098.
      View in: PubMed
    16. Husain AM, Lee JW, Kolls BJ, Hirsch LJ, Halford JJ, Gupta PK, Minazad Y, Jones JM, LaRoche SM, Herman ST, Swisher CB, Sinha SR, Palade A, Dombrowski KE, Gallentine WB, Hahn CD, Gerard EE, Bhapkar M, Lokhnygina Y, Westover MB. Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures. Ann Neurol. 2018 06; 83(6):1174-1185. PMID: 29733464.
      View in: PubMed
    17. Hirsch LJ, Gaspard N, van Baalen A, Nabbout R, Demeret S, Loddenkemper T, Navarro V, Specchio N, Lagae L, Rossetti AO, Hocker S, Gofton TE, Abend NS, Gilmore EJ, Hahn C, Khosravani H, Rosenow F, Trinka E. Proposed consensus definitions for new-onset refractory status epilepticus (NORSE), febrile infection-related epilepsy syndrome (FIRES), and related conditions. Epilepsia. 2018 04; 59(4):739-744. PMID: 29399791.
      View in: PubMed
    18. Uddin M, Woodbury-Smith M, Chan A, Brunga L, Lamoureux S, Pellecchia G, Yuen RKC, Faheem M, Stavropoulos DJ, Drake J, Hahn CD, Hawkins C, Shlien A, Marshall CR, Turner LA, Minassian BA, Scherer SW, Boelman C. Germline and somatic mutations in STXBP1 with diverse neurodevelopmental phenotypes. Neurol Genet. 2017 Dec; 3(6):e199. PMID: 29264391.
      View in: PubMed
    19. Pinchefsky EF, Hahn CD. Outcomes following electrographic seizures and electrographic status epilepticus in the pediatric and neonatal ICUs. Curr Opin Neurol. 2017 04; 30(2):156-164. PMID: 28118303.
      View in: PubMed
    20. Birca A, Vakorin VA, Porayette P, Madathil S, Chau V, Seed M, Doesburg SM, Blaser S, Nita DA, Sharma R, Duerden EG, Hickey EJ, Miller SP, Hahn CD. Interplay of brain structure and function in neonatal congenital heart disease. Ann Clin Transl Neurol. 2016 09; 3(9):708-22. PMID: 27648460.
      View in: PubMed
    21. Haider HA, Esteller R, Hahn CD, Westover MB, Halford JJ, Lee JW, Shafi MM, Gaspard N, Herman ST, Gerard EE, Hirsch LJ, Ehrenberg JA, LaRoche SM. Sensitivity of quantitative EEG for seizure identification in the intensive care unit. Neurology. 2016 Aug 30; 87(9):935-44. PMID: 27466474.
      View in: PubMed
    22. Hahn CD. Electroencephalographic Monitoring for Prognostication Following Cardiac Arrest: Ready for Prime Time? Pediatr Crit Care Med. 2016 06; 17(6):572-3. PMID: 27261650.
      View in: PubMed
    23. Nita DA, Moldovan M, Sharma R, Avramescu S, Otsubo H, Hahn CD. Burst-suppression is reactive to photic stimulation in comatose children with acquired brain injury. Clin Neurophysiol. 2016 08; 127(8):2921-2930. PMID: 27266662.
      View in: PubMed
    24. Lee JW, LaRoche S, Choi H, Rodriguez Ruiz AA, Fertig E, Politsky JM, Herman ST, Loddenkemper T, Sansevere AJ, Korb PJ, Abend NS, Goldstein JL, Sinha SR, Dombrowski KE, Ritzl EK, Westover MB, Gavvala JR, Gerard EE, Schmitt SE, Szaflarski JP, Ding K, Haas KF, Buchsbaum R, Hirsch LJ, Wusthoff CJ, Hopp JL, Hahn CD. Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research. J Clin Neurophysiol. 2016 Apr; 33(2):133-40. PMID: 26943901.
      View in: PubMed
    25. McBain KL, Payne ET, Sharma R, Frndova H, Abend NS, Sánchez SM, Gallentine WB, Cornett KM, Nash KB, Snead OC, Parshuram CS, Hutchison JS, Hahn CD. Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med. 2016 Mar; 17(3):246-50. PMID: 26825045.
      View in: PubMed
    26. Nita DA, Hahn CD. Levetiracetam for Pediatric Posttraumatic Seizure Prophylaxis. Pediatr Neurol Briefs. 2016 Mar; 30(3):18. PMID: 27396956.
      View in: PubMed
    27. Herman ST, Abend NS, Bleck TP, Chapman KE, Drislane FW, Emerson RG, Gerard EE, Hahn CD, Husain AM, Kaplan PW, LaRoche SM, Nuwer MR, Quigg M, Riviello JJ, Schmitt SE, Simmons LA, Tsuchida TN, Hirsch LJ. Consensus statement on continuous EEG in critically ill adults and children, part II: personnel, technical specifications, and clinical practice. J Clin Neurophysiol. 2015 Apr; 32(2):96-108. PMID: 25626777.
      View in: PubMed
    28. Herman ST, Abend NS, Bleck TP, Chapman KE, Drislane FW, Emerson RG, Gerard EE, Hahn CD, Husain AM, Kaplan PW, LaRoche SM, Nuwer MR, Quigg M, Riviello JJ, Schmitt SE, Simmons LA, Tsuchida TN, Hirsch LJ. Consensus statement on continuous EEG in critically ill adults and children, part I: indications. J Clin Neurophysiol. 2015 Apr; 32(2):87-95. PMID: 25626778.
      View in: PubMed
    29. Mercimek-Mahmutoglu S, Patel J, Cordeiro D, Hewson S, Callen D, Donner EJ, Hahn CD, Kannu P, Kobayashi J, Minassian BA, Moharir M, Siriwardena K, Weiss SK, Weksberg R, Snead OC. Diagnostic yield of genetic testing in epileptic encephalopathy in childhood. Epilepsia. 2015 May; 56(5):707-16. PMID: 25818041.
      View in: PubMed
    30. Payne ET, Hahn CD. Continuous electroencephalography for seizures and status epilepticus. Curr Opin Pediatr. 2014 Dec; 26(6):675-81. PMID: 25313973.
      View in: PubMed
    31. Yang A, Arndt DH, Berg RA, Carpenter JL, Chapman KE, Dlugos DJ, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Lerner JT, Loddenkemper T, Matsumoto JH, Nash KB, Payne ET, Sánchez Fernández I, Shults J, Topjian AA, Williams K, Wusthoff CJ, Abend NS. Development and validation of a seizure prediction model in critically ill children. Seizure. 2015 Feb; 25:104-11. PMID: 25458097.
      View in: PubMed
    32. Gavvala J, Abend N, LaRoche S, Hahn C, Herman ST, Claassen J, Macken M, Schuele S, Gerard E. Continuous EEG monitoring: a survey of neurophysiologists and neurointensivists. Epilepsia. 2014 Nov; 55(11):1864-71. PMID: 25266728.
      View in: PubMed
    33. Payne ET, Hahn CD. Reply: The circular dilemma of seizure-induced brain injury. Brain. 2014 Nov; 137(Pt 11):e306. PMID: 24993960.
      View in: PubMed
    34. Gaspard N, Hirsch LJ, LaRoche SM, Hahn CD, Westover MB. Interrater agreement for Critical Care EEG Terminology. Epilepsia. 2014 Sep; 55(9):1366-73. PMID: 24888711.
      View in: PubMed
    35. Jain-Ghai S, Mishra N, Hahn C, Blaser S, Mercimek-Mahmutoglu S. Fetal onset ventriculomegaly and subependymal cysts in a pyridoxine dependent epilepsy patient. Pediatrics. 2014 Apr; 133(4):e1092-6. PMID: 24664088.
      View in: PubMed
    36. Payne ET, Zhao XY, Frndova H, McBain K, Sharma R, Hutchison JS, Hahn CD. Seizure burden is independently associated with short term outcome in critically ill children. Brain. 2014 May; 137(Pt 5):1429-38. PMID: 24595203.
      View in: PubMed
    37. Hahn CD, Jette N. Neurocritical care: Seizures after acute brain injury--more than meets the eye. Nat Rev Neurol. 2013 Dec; 9(12):662-4. PMID: 24247323.
      View in: PubMed
    38. Sánchez Fernández I, Abend NS, Arndt DH, Carpenter JL, Chapman KE, Cornett KM, Dlugos DJ, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Lerner JT, Matsumoto JH, McBain K, Nash KB, Payne E, Sánchez SM, Williams K, Loddenkemper T. Electrographic seizures after convulsive status epilepticus in children and young adults: a retrospective multicenter study. J Pediatr. 2014 Feb; 164(2):339-46.e1-2. PMID: 24161223.
      View in: PubMed
    39. Sánchez Fernández I, Abend NS, Agadi S, An S, Arya R, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goldstein DB, Goldstein JL, Goodkin HP, Hahn CD, Heinzen EL, Mikati MA, Peariso K, Pestian JP, Ream M, Riviello JJ, Tasker RC, Williams K, Loddenkemper T. Gaps and opportunities in refractory status epilepticus research in children: a multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG). Seizure. 2014 Feb; 23(2):87-97. PMID: 24183923.
      View in: PubMed
    40. Sánchez SM, Arndt DH, Carpenter JL, Chapman KE, Cornett KM, Dlugos DJ, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Lerner JT, Loddenkemper T, Matsumoto JH, McBain K, Nash KB, Payne E, Sánchez Fernández I, Shults J, Williams K, Yang A, Abend NS. Electroencephalography monitoring in critically ill children: current practice and implications for future study design. Epilepsia. 2013 Aug; 54(8):1419-27. PMID: 23848569.
      View in: PubMed
    41. Hahn CD. To cool or not to cool: does neonatal cord blood provide the answer? Pediatr Crit Care Med. 2013 Jul; 14(6):650-1. PMID: 23823203.
      View in: PubMed
    42. Abend NS, Arndt DH, Carpenter JL, Chapman KE, Cornett KM, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Lerner JT, Loddenkemper T, Matsumoto JH, McBain K, Nash KB, Payne E, Sánchez SM, Fernández IS, Shults J, Williams K, Yang A, Dlugos DJ. Electrographic seizures in pediatric ICU patients: cohort study of risk factors and mortality. Neurology. 2013 Jul 23; 81(4):383-91. PMID: 23794680.
      View in: PubMed
    43. Gaspard N, Foreman B, Judd LM, Brenton JN, Nathan BR, McCoy BM, Al-Otaibi A, Kilbride R, Fernández IS, Mendoza L, Samuel S, Zakaria A, Kalamangalam GP, Legros B, Szaflarski JP, Loddenkemper T, Hahn CD, Goodkin HP, Claassen J, Hirsch LJ, Laroche SM. Intravenous ketamine for the treatment of refractory status epilepticus: a retrospective multicenter study. Epilepsia. 2013 Aug; 54(8):1498-503. PMID: 23758557.
      View in: PubMed
    44. McCoy B, Hahn CD. Continuous EEG monitoring in the neonatal intensive care unit. J Clin Neurophysiol. 2013 Apr; 30(2):106-14. PMID: 23545760.
      View in: PubMed
    45. Sanchez SM, Carpenter J, Chapman KE, Dlugos DJ, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Kessler SK, Loddenkemper T, Riviello JJ, Abend NS. Pediatric ICU EEG monitoring: current resources and practice in the United States and Canada. J Clin Neurophysiol. 2013 Apr; 30(2):156-60. PMID: 23545766.
      View in: PubMed
    46. Tsuchida TN, Wusthoff CJ, Shellhaas RA, Abend NS, Hahn CD, Sullivan JE, Nguyen S, Weinstein S, Scher MS, Riviello JJ, Clancy RR. American clinical neurophysiology society standardized EEG terminology and categorization for the description of continuous EEG monitoring in neonates: report of the American Clinical Neurophysiology Society critical care monitoring committee. J Clin Neurophysiol. 2013 Apr; 30(2):161-73. PMID: 23545767.
      View in: PubMed
    47. Abend NS, Chapman KE, Gallentine WB, Goldstein J, Hyslop AE, Loddenkemper T, Nash KB, Riviello JJ, Hahn CD. Electroencephalographic monitoring in the pediatric intensive care unit. Curr Neurol Neurosci Rep. 2013 Mar; 13(3):330. PMID: 23335026.
      View in: PubMed
    48. Appendino JP, McNamara PJ, Keyzers M, Stephens D, Hahn CD. The impact of amplitude-integrated electroencephalography on NICU practice. Can J Neurol Sci. 2012 May; 39(3):355-60. PMID: 22547518.
      View in: PubMed
    49. McCoy B, Sharma R, Ochi A, Go C, Otsubo H, Hutchison JS, Atenafu EG, Hahn CD. Predictors of nonconvulsive seizures among critically ill children. Epilepsia. 2011 Nov; 52(11):1973-8. PMID: 22003955.
      View in: PubMed
    50. Hahn CD, Manlhiot C, Schmidt MR, Nielsen TT, Redington AN. Remote ischemic per-conditioning: a novel therapy for acute stroke? Stroke. 2011 Oct; 42(10):2960-2. PMID: 21836089.
      View in: PubMed
    51. Hahn CD. Nonconvulsive seizures among critically ill children: look and you shall find. Neurology. 2011 Mar 22; 76(12):1036-7. PMID: 21307356.
      View in: PubMed
    52. Stewart CP, Otsubo H, Ochi A, Sharma R, Hutchison JS, Hahn CD. Seizure identification in the ICU using quantitative EEG displays. Neurology. 2010 Oct 26; 75(17):1501-8. PMID: 20861452.
      View in: PubMed
    53. Abend NS, Dlugos DJ, Hahn CD, Hirsch LJ, Herman ST. Use of EEG monitoring and management of non-convulsive seizures in critically ill patients: a survey of neurologists. Neurocrit Care. 2010 Jun; 12(3):382-9. PMID: 20198513.
      View in: PubMed
    54. Trakadis Y, Blaser S, Hahn CD, Yoon G. A case report of prenatal exposure to rosuvastatin and telmisartan. Paediatr Child Health. 2009 Sep; 14(7):450-2. PMID: 20808473.
      View in: PubMed
    55. Verboon-Maciolek MA, Groenendaal F, Hahn CD, Hellmann J, van Loon AM, Boivin G, de Vries LS. Human parechovirus causes encephalitis with white matter injury in neonates. Ann Neurol. 2008 Sep; 64(3):266-73. PMID: 18825694.
      View in: PubMed
    56. Datta AN, Hahn CD, Sahin M. Clinical presentation and diagnosis of tuberous sclerosis complex in infancy. J Child Neurol. 2008 Mar; 23(3):268-73. PMID: 18230839.
      View in: PubMed
    57. Hahn CD. The ARX story: a new twist. Neurology. 2007 Jul 31; 69(5):421-2. PMID: 17664398.
      View in: PubMed
    58. Kuban KC, O'Shea M, Allred E, Leviton A, Gilmore H, DuPlessis A, Krishnamoorthy K, Hahn C, Soul J, O'Connor SE, Miller K, Church PT, Keller C, Bream R, Adair R, Miller A, Romano E, Bassan H, Kerkering K, Engelke S, Marshall D, Milowic K, Wereszczak J, Hubbard C, Washburn L, Dillard R, Heller C, Burdo-Hartman W, Fagerman L, Sutton D, Karna P, Olomu N, Caldarelli L, Oca M, Lohr K, Scheiner A. Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic study. J Child Neurol. 2005 Oct; 20(10):829-31. PMID: 16417880.
      View in: PubMed
    59. Hahn CD, Shroff MM, Blaser SI, Banwell BL. MRI criteria for multiple sclerosis: Evaluation in a pediatric cohort. Neurology. 2004 Mar 09; 62(5):806-8. PMID: 15007138.
      View in: PubMed
    60. Hahn CD, Miles BS, MacGregor DL, Blaser SI, Banwell BL, Hetherington CR. Neurocognitive outcome after acute disseminated encephalomyelitis. Pediatr Neurol. 2003 Aug; 29(2):117-23. PMID: 14580654.
      View in: PubMed
    61. Hahn CD, Nicolle DA, Lownie SP, Drake CG. Giant cavernous carotid aneurysms: clinical presentation in fifty-seven cases. J Neuroophthalmol. 2000 Dec; 20(4):253-8. PMID: 11130752.
      View in: PubMed
    62. Nishino I, Spinazzola A, Papadimitriou A, Hammans S, Steiner I, Hahn CD, Connolly AM, Verloes A, Guimarães J, Maillard I, Hamano H, Donati MA, Semrad CE, Russell JA, Andreu AL, Hadjigeorgiou GM, Vu TH, Tadesse S, Nygaard TG, Nonaka I, Hirano I, Bonilla E, Rowland LP, DiMauro S, Hirano M. Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations. Ann Neurol. 2000 Jun; 47(6):792-800. PMID: 10852545.
      View in: PubMed
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