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Laura Janzen

TitlePsychologist PhD (MU)
InstitutionThe Hospital for Sick Children
DepartmentPsychology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Biography 
    Collapse education and training
    University of Victoria , Victoria BC Ph.D. 2001Clinical Psychology (Clinical Neuropsychology emphasis)
    University of Rochester Medical Center , Rochester NY Post-Doctoral Fellowship2002Clinical Neuropsychology

    Collapse Overview 
    Collapse overview
    Training and Experience:
    Following completion of a PhD in clinical psychology (clinical neuropsychology specialization) at the University of Victoria, including a one-year clinical internship at the London Health Sciences Centre, I pursued post-doctoral training in clinical neuropsychology at the University of Rochester Medical Center in Rochester, NY. I was then employed as a staff neuropsychologist in the Epilepsy Program at London Health Sciences Centre in London, ON from 2002 to 2005. From 2005 to 2007, I was employed as a staff neuropsychologist at Holland Bloorview Kids Rehabilitation in Toronto, ON. I have been in my current position as a staff neuropsychologist in the Division of Haematology/Oncology at The Hospital for Sick Children since 2007.

    Clinical Activities:
    I provide neuropsychological assessment and consultation services primarily to patients in the Neuro-Oncology, Leukemia/Lymphoma and Sickle Cell Disease programs, although I see patients with other diagnoses as well. I am also coordinator of post-doctoral neuropsychology training in the Department of Psychology.

    Research:
    My research focuses on the evaluation and treatment of cognitive deficits associated with medical and neurological disorders. In the past, my work has included studies of the cognitive implications of neuronal migration disorders (e.g., subcortical band heterotopia), seizure disorders, Tourette’s syndrome and Fetal Alcohol Syndrome (FAS). I have co-authored two Cochrane reviews of the effects of nutritional programs for children (e.g., school feeding) on physical and cognitive outcomes.

    Currently, my research explores the neurocognitive outcomes of children with leukemia, brain tumors and sickle cell disease. In particular, I am interested in individual variables that moderate disease and treatment-related neurocognitive deficits.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Conklin HM, Chintagumpala M, Bouffet E, Mabbott D. Superior Intellectual Outcomes After Proton Radiotherapy Compared With Photon Radiotherapy for Pediatric Medulloblastoma. J Clin Oncol. 2019 Nov 27; JCO1901706. PMID: 31774710.
      View in: PubMed
    2. de Medeiros CB, Moxon-Emre I, Scantlebury N, Malkin D, Ramaswamy V, Decker A, Law N, Kumabe T, Leonard J, Rubin J, Jung S, Kim SK, Gupta N, Weiss W, Faria CC, Vibhakar R, Lafay-Cousin L, Chan J, Kros JM, Janzen L, Taylor MD, Bouffet E, Mabbott DJ. Medulloblastoma has a global impact on health related quality of life: Findings from an international cohort. Cancer Med. 2019 Nov 21. PMID: 31755223.
      View in: PubMed
    3. Schulte F, Kunin-Batson AS, Olson-Bullis BA, Banerjee P, Hocking MC, Janzen L, Kahalley LS, Wroot H, Forbes C, Krull KR. Social attainment in survivors of pediatric central nervous system tumors: a systematic review and meta-analysis from the Children's Oncology Group. J Cancer Surviv. 2019 Dec; 13(6):921-931. PMID: 31625086.
      View in: PubMed
    4. Desjardins L, Barrera M, Chung J, Cataudella D, Janzen L, Bartels U, Downie A, Fairclough D. Are we friends? Best friend nominations in pediatric brain tumor survivors and associated factors. Support Care Cancer. 2019 Nov; 27(11):4237-4244. PMID: 30847703.
      View in: PubMed
    5. Zapotocky M, Beera K, Adamski J, Laperierre N, Guger S, Janzen L, Lassaletta A, Figueiredo Nobre L, Bartels U, Tabori U, Hawkins C, Urbach S, Tsang DS, Dirks PB, Taylor MD, Bouffet E, Mabbott DJ, Ramaswamy V. Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost. Cancer. 2019 Jun 01; 125(11):1867-1876. PMID: 30768777.
      View in: PubMed
    6. Desjardins L, Barrera M, Schulte F, Chung J, Cataudella D, Janzen L, Bartels U, Downie A. Predicting social withdrawal, anxiety and depression symptoms in pediatric brain tumor survivors. J Psychosoc Oncol. 2019 Jan-Feb; 37(1):22-36. PMID: 30614410.
      View in: PubMed
    7. Desjardins L, Solomon A, Janzen L, Bartels U, Schulte F, Chung J, Cataudella D, Downie A, Barrera M. Executive functions and social skills in pediatric brain tumor survivors. Appl Neuropsychol Child. 2018 Nov 30; 1-9. PMID: 30501139.
      View in: PubMed
    8. Barrera M, Atenafu EG, Schulte F, Bartels U, Sung L, Janzen L, Chung J, Cataudella D, Hancock K, Saleh A, Strother D, McConnell D, Downie A, Hukin J, Zelcer S. Determinants of social competence in pediatric brain tumor survivors who participated in an intervention study. Support Care Cancer. 2017 09; 25(9):2891-2898. PMID: 28411324.
      View in: PubMed
    9. Barrera M, Atenafu EG, Schulte F, Bartels U, Sung L, Janzen L, Chung J, Cataudella D, Hancock K, Saleh A, Strother D, McConnell D, Downie A, Hukin J, Zelcer S. Determinants of quality of life outcomes for survivors of pediatric brain tumors. Pediatr Blood Cancer. 2017 Sep; 64(9). PMID: 28296130.
      View in: PubMed
    10. Barrera M, Atenafu EG, Sung L, Bartels U, Schulte F, Chung J, Cataudella D, Hancock K, Janzen L, Saleh A, Strother D, Downie A, Zelcer S, Hukin J, McConnell D. A randomized control intervention trial to improve social skills and quality of life in pediatric brain tumor survivors. Psychooncology. 2018 01; 27(1):91-98. PMID: 28124799.
      View in: PubMed
    11. Baum KT, Powell SK, Jacobson LA, Gragert MN, Janzen LA, Paltin I, Rey-Casserly CM, Wilkening GN. Implementing guidelines: Proposed definitions of neuropsychology services in pediatric oncology. Pediatr Blood Cancer. 2017 Aug; 64(8). PMID: 28121073.
      View in: PubMed
    12. Moxon-Emre I, Taylor MD, Bouffet E, Hardy K, Campen CJ, Malkin D, Hawkins C, Laperriere N, Ramaswamy V, Bartels U, Scantlebury N, Janzen L, Law N, Walsh KS, Mabbott DJ. Intellectual Outcome in Molecular Subgroups of Medulloblastoma. J Clin Oncol. 2016 12; 34(34):4161-4170. PMID: 27507873.
      View in: PubMed
    13. Janzen LA. Long-term neurocognitive and functional effects of treatment for childhood acute lymphoblastic leukaemia. Lancet Psychiatry. 2016 10; 3(10):912-913. PMID: 27639662.
      View in: PubMed
    14. Janzen LA, Guger S. Clinical neuropsychology practice and training in Canada. Clin Neuropsychol. 2016 Nov; 30(8):1193-1206. PMID: 27684307.
      View in: PubMed
    15. Cheng S, Kilday JP, Laperriere N, Janzen L, Drake J, Bouffet E, Bartels U. Outcomes of children with central nervous system germinoma treated with multi-agent chemotherapy followed by reduced radiation. J Neurooncol. 2016 Mar; 127(1):173-80. PMID: 26744133.
      View in: PubMed
    16. Janzen LA, David D, Walker D, Hitzler J, Zupanec S, Jones H, Spiegler BJ. Pre-Morbid Developmental Vulnerabilities in Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL). Pediatr Blood Cancer. 2015 Dec; 62(12):2183-8. PMID: 26305495.
      View in: PubMed
    17. Lafay-Cousin L, Fay-McClymont T, Johnston D, Fryer C, Scheinemann K, Fleming A, Hukin J, Janzen L, Guger S, Strother D, Mabbott D, Huang A, Bouffet E. Neurocognitive evaluation of long term survivors of atypical teratoid rhabdoid tumors (ATRT): The Canadian registry experience. Pediatr Blood Cancer. 2015 Jul; 62(7):1265-9. PMID: 25787232.
      View in: PubMed
    18. Kristjansson E, Francis DK, Liberato S, Benkhalti Jandu M, Welch V, Batal M, Greenhalgh T, Rader T, Noonan E, Shea B, Janzen L, Wells GA, Petticrew M. Food supplementation for improving the physical and psychosocial health of socio-economically disadvantaged children aged three months to five years. Cochrane Database Syst Rev. 2015 Mar 05; (3):CD009924. PMID: 25739460.
      View in: PubMed
    19. Moxon-Emre I, Bouffet E, Taylor MD, Laperriere N, Scantlebury N, Law N, Spiegler BJ, Malkin D, Janzen L, Mabbott D. Impact of craniospinal dose, boost volume, and neurologic complications on intellectual outcome in patients with medulloblastoma. J Clin Oncol. 2014 Jun 10; 32(17):1760-8. PMID: 24516024.
      View in: PubMed
    20. Brinkman TM, Palmer SL, Chen S, Zhang H, Evankovich K, Swain MA, Bonner MJ, Janzen L, Knight S, Armstrong CL, Boyle R, Gajjar A. Parent-reported social outcomes after treatment for pediatric embryonal tumors: a prospective longitudinal study. J Clin Oncol. 2012 Nov 20; 30(33):4134-40. PMID: 23071220.
      View in: PubMed
    21. Mabbott DJ, Monsalves E, Spiegler BJ, Bartels U, Janzen L, Guger S, Laperriere N, Andrews N, Bouffet E. Longitudinal evaluation of neurocognitive function after treatment for central nervous system germ cell tumors in childhood. Cancer. 2011 Dec 01; 117(23):5402-11. PMID: 21563173.
      View in: PubMed
    22. Palmer SL, Lesh S, Wallace D, Bonner MJ, Swain M, Chapieski L, Janzen L, Mabbott D, Knight S, Boyle R, Armstrong CL, Gajjar A. How parents cope with their child's diagnosis and treatment of an embryonal tumor: results of a prospective and longitudinal study. J Neurooncol. 2011 Nov; 105(2):253-9. PMID: 21499990.
      View in: PubMed
    23. Scantlebury N, Mabbott D, Janzen L, Rockel C, Widjaja E, Jones G, Kirby M, Odame I. White matter integrity and core cognitive function in children diagnosed with sickle cell disease. J Pediatr Hematol Oncol. 2011 Apr; 33(3):163-71. PMID: 21325970.
      View in: PubMed
    24. Schulte F, Bartels U, Bouffet E, Janzen L, Hamilton J, Barrera M. Body weight, social competence, and cognitive functioning in survivors of childhood brain tumors. Pediatr Blood Cancer. 2010 Sep; 55(3):532-9. PMID: 20658626.
      View in: PubMed
    25. Finkelstein-Shechter T, Gassas A, Mabbott D, Huang A, Bartels U, Tabori U, Janzen L, Laura J, Hawkins C, Taylor M, Bouffet E. Atypical teratoid or rhabdoid tumors: improved outcome with high-dose chemotherapy. J Pediatr Hematol Oncol. 2010 Jul; 32(5):e182-6. PMID: 20495479.
      View in: PubMed
    26. Bowles B, Crupi C, Pigott S, Parrent A, Wiebe S, Janzen L, Köhler S. Double dissociation of selective recollection and familiarity impairments following two different surgical treatments for temporal-lobe epilepsy. Neuropsychologia. 2010 Jul; 48(9):2640-7. PMID: 20466009.
      View in: PubMed
    27. Nathan PC, Wasilewski-Masker K, Janzen LA. Long-term outcomes in survivors of childhood acute lymphoblastic leukemia. Hematol Oncol Clin North Am. 2009 Oct; 23(5):1065-82, vi-vii. PMID: 19825453.
      View in: PubMed
    28. Janzen LA, Spiegler BJ. Neurodevelopmental sequelae of pediatric acute lymphoblastic leukemia and its treatment. Dev Disabil Res Rev. 2008; 14(3):185-95. PMID: 18924154.
      View in: PubMed
    29. Danckert J, Mirsattari SM, Bihari F, Danckert S, Allman AA, Janzen L. Functional MRI characteristics of a focal region of cortical malformation not associated with seizure onset. Epilepsy Behav. 2007 Jun; 10(4):615-25. PMID: 17482882.
      View in: PubMed
    30. Kristjansson EA, Robinson V, Petticrew M, MacDonald B, Krasevec J, Janzen L, Greenhalgh T, Wells G, MacGowan J, Farmer A, Shea BJ, Mayhew A, Tugwell P. School feeding for improving the physical and psychosocial health of disadvantaged elementary school children. Cochrane Database Syst Rev. 2007 Jan 24; (1):CD004676. PMID: 17253518.
      View in: PubMed
    31. Janzen L, Sherman E, Langfitt J, Berg M, Connolly M. Preserved episodic memory in subcortical band heterotopia. Epilepsia. 2004 May; 45(5):555-8. PMID: 15101838.
      View in: PubMed
    32. Pharis RP, Janzen L, Nakajima SK, Zhu J, Back TG. Bioactivity of 25-hydroxy-, 26-hydroxy, 25,26-dihydroxy- and 25,26-epoxybrassinolide. Phytochemistry. 2001 Dec; 58(7):1043-7. PMID: 11730867.
      View in: PubMed
    33. Sung GC, Janzen L, Pharis RP, Back TG. Synthesis and bioactivity of 6alpha- and 6beta-hydroxy analogues of castasterone. Phytochemistry. 2000 Sep; 55(2):121-6. PMID: 11065287.
      View in: PubMed
    34. Janzen LA, Nanson JL, Block GW. Neuropsychological evaluation of preschoolers with fetal alcohol syndrome. Neurotoxicol Teratol. 1995 May-Jun; 17(3):273-9. PMID: 7623737.
      View in: PubMed
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