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Sarah Alexander

TitleStaff Physician
InstitutionThe Hospital for Sick Children
DepartmentHaematology/Oncology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tang N, Kovacevic A, Zupanec S, Sivananthan A, Patel R, Patel P, Vennettilli A, Paw Cho Sing E, Alexander S, Sung L, Dupuis LL. Perceptions of parents of pediatric patients with acute lymphoblastic leukemia on oral chemotherapy administration: A qualitative analysis. Pediatr Blood Cancer. 2021 Sep 07; e29329. PMID: 34492743.
      View in: PubMed
    2. Mark C, Gupta S, Punnett A, Upton J, Orkin J, Atkinson A, Clarke L, Heisey A, McGovern C, Alexander S. Safety of administration of BNT162b2 mRNA (Pfizer-BioNTech) COVID-19 vaccine in youths and young adults with a history of acute lymphoblastic leukemia and allergy to PEG-asparaginase. Pediatr Blood Cancer. 2021 Aug 16; e29295. PMID: 34398511.
      View in: PubMed
    3. Raffa EH, Branson HM, Ngan B, Alexander S, Abla O. Central nervous system relapse in a child with anaplastic large cell lymphoma: potential for new therapeutic strategies. Cancer Rep (Hoboken). 2021 Apr 06; e1377. PMID: 33822480.
      View in: PubMed
    4. Shaikh F, Arzola C, Alexander S, Carvalho JCA, Everett T, Shroff M, Doria AS, Trottier L, To T, Sung L. Feasibility of ultrasound-assisted lumbar punctures performed by pediatric oncologists at the point of care. Pediatr Blood Cancer. 2021 Jul; 68(7):e29015. PMID: 33764681.
      View in: PubMed
    5. Raghuram N, Alodan K, Bartels U, Alexander S, Pole JD, Gibson P, Johnston DL, Portwine C, Silva M, Sung L. Diagnostic discrepancies between antemortem clinical diagnosis and autopsy findings in pediatric cancer patients. Virchows Arch. 2021 Jun; 478(6):1179-1185. PMID: 33392797.
      View in: PubMed
    6. Maser B, Pelland-Marcotte MC, Alexander S, Sung L, Gupta S. Levofloxacin prophylaxis in hospitalized children with leukemia: A cost-utility analysis. Pediatr Blood Cancer. 2020 10; 67(10):e28643. PMID: 32785971.
      View in: PubMed
    7. Egan G, Athale U, Johnston D, Pole JD, Silva M, Zorzi A, Alexander S. Outcomes of children with chronic myeloid leukemia: A population-based cohort study. Pediatr Blood Cancer. 2020 09; 67(9):e28491. PMID: 32589368.
      View in: PubMed
    8. Minard-Colin V, Aupérin A, Pillon M, Burke GAA, Barkauskas DA, Wheatley K, Delgado RF, Alexander S, Uyttebroeck A, Bollard CM, Zsiros J, Csoka M, Kazanowska B, Chiang AK, Miles RR, Wotherspoon A, Adamson PC, Vassal G, Patte C, Gross TG. Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children. N Engl J Med. 2020 06 04; 382(23):2207-2219. PMID: 32492302.
      View in: PubMed
    9. Barrera M, Hancock K, Atenafu E, Alexander S, Solomon A, Desjardins L, Shama W, Chung J, Mills D. Quality of life in pediatric oncology patients, caregivers and siblings after psychosocial screening: a randomized controlled trial. Support Care Cancer. 2020 Aug; 28(8):3659-3668. PMID: 31811485.
      View in: PubMed
    10. Alexander S, Science M, Breakey V, Clarke A, Gibson P. Recommendations for medical care in the pediatric oncology camp setting: Consensus statements based on Delphi methodology. Pediatr Blood Cancer. 2020 03; 67(3):e28107. PMID: 31797560.
      View in: PubMed
    11. Kovacevic A, Sivananthan A, Patel R, Patel P, Vennettilli A, Paw Cho Sing E, Zupanec S, Alexander S, Sung L, Dupuis LL. Chemotherapy-induced nausea and vomiting from oral chemotherapy for childhood acute lymphoblastic leukaemia: feasibility study. BMJ Support Palliat Care. 2019 Nov 29. PMID: 31784465.
      View in: PubMed
    12. Desjardins L, Etkin-Spigelman L, Hancock K, Chung J, Shama W, Mills D, Alexander S, Barrera M. Healthcare provider utility ratings of a psychosocial screening summary: from diagnosis to 6 months. Support Care Cancer. 2020 Apr; 28(4):1717-1723. PMID: 31292754.
      View in: PubMed
    13. Egan G, Robinson PD, Martinez JPD, Alexander S, Ammann RA, Dupuis LL, Fisher BT, Lehrnbecher T, Phillips B, Cabral S, Tomlinson G, Sung L. Efficacy of antibiotic prophylaxis in patients with cancer and hematopoietic stem cell transplantation recipients: A systematic review of randomized trials. Cancer Med. 2019 08; 8(10):4536-4546. PMID: 31274245.
      View in: PubMed
    14. Egan G, Goldman S, Alexander S. Mature B-NHL in children, adolescents and young adults: current therapeutic approach and emerging treatment strategies. Br J Haematol. 2019 06; 185(6):1071-1085. PMID: 30613948.
      View in: PubMed
    15. Alexander S, Fisher BT, Gaur AH, Dvorak CC, Villa Luna D, Dang H, Chen L, Green M, Nieder ML, Fisher B, Bailey LC, Wiernikowski J, Sung L. Effect of Levofloxacin Prophylaxis on Bacteremia in Children With Acute Leukemia or Undergoing Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial. JAMA. 2018 09 11; 320(10):995-1004. PMID: 30208456.
      View in: PubMed
    16. Barrera M, Alexander S, Shama W, Mills D, Desjardins L, Hancock K. Perceived benefits of and barriers to psychosocial risk screening in pediatric oncology by health care providers. Pediatr Blood Cancer. 2018 12; 65(12):e27429. PMID: 30160072.
      View in: PubMed
    17. Alexander S, Greenberg M, Malkin D, Portwine C, Johnston D, Silva M, Zelcer S, Sonshine S, Manzo J, Bennett C, Brodeur-Robb K, Deveault C, Ramachandran N, Gibson P. Pediatric oncology clinical trial participation where the geography is vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada. Pediatr Blood Cancer. 2018 04; 65(4). PMID: 29271602.
      View in: PubMed
    18. Lehrnbecher T, Robinson P, Fisher B, Alexander S, Ammann RA, Beauchemin M, Carlesse F, Groll AH, Haeusler GM, Santolaya M, Steinbach WJ, Castagnola E, Davis BL, Dupuis LL, Gaur AH, Tissing WJE, Zaoutis T, Phillips R, Sung L. Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update. J Clin Oncol. 2017 Jun 20; 35(18):2082-2094. PMID: 28459614.
      View in: PubMed
    19. Even-Or E, Di Mola M, Ali M, Courtney S, McDougall E, Alexander S, Schechter T, Whitlock JA, Licht C, Krueger J. Optimizing autologous nonmobilized mononuclear cell collections for cellular therapy in pediatric patients with high-risk leukemia. Transfusion. 2017 06; 57(6):1536-1542. PMID: 28439898.
      View in: PubMed
    20. Ceppi F, Weitzman S, Woessmann W, Davies K, Lassaletta A, Reismüller B, Mellgren K, Uyttebroeck A, Maia I, Abdullah S, Miakova N, Glaser D, Cohn R, Abla O, Attarbaschi A, Alexander S. Safety and efficacy of intrathecal rituximab in children with B cell lymphoid CD20+ malignancies: An international retrospective study. Am J Hematol. 2016 May; 91(5):486-91. PMID: 26872652.
      View in: PubMed
    21. Alexander S, Pole JD, Gibson P, Lee M, Hesser T, Chi SN, Dvorak CC, Fisher B, Hasle H, Kanerva J, Möricke A, Phillips B, Raetz E, Rodriguez-Galindo C, Samarasinghe S, Schmiegelow K, Tissing W, Lehrnbecher T, Sung L. Classification of treatment-related mortality in children with cancer: a systematic assessment. Lancet Oncol. 2015 Dec; 16(16):e604-10. PMID: 26678213.
      View in: PubMed
    22. Shaikh F, Dupuis LL, Alexander S, Gupta A, Mertens L, Nathan PC. Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-Analysis. J Natl Cancer Inst. 2016 Apr; 108(4). PMID: 26598513.
      View in: PubMed
    23. Brulé D, Gillmeister B, Lee M, Alexander S, Gassas A, Hendershot E, Zupanec S, Dupuis L, Sung L. A Feasibility Pilot Trial of Individualized Homeopathic Treatment of Fatigue in Children Receiving Chemotherapy. Integr Cancer Ther. 2016 12; 15(4):495-501. PMID: 26574487.
      View in: PubMed
    24. Grant RC, Shaikh F, Abdelhaleem M, Alexander SW, Cada M. Risk factors for inadequate bone marrow biopsies in children. Am J Hematol. 2015 Sep; 90(9):E187-9. PMID: 26043864.
      View in: PubMed
    25. Kassam A, Skiadaresis J, Alexander S, Wolfe J. Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care team. Pediatr Blood Cancer. 2015 Aug; 62(8):1409-13. PMID: 25882665.
      View in: PubMed
    26. DiLabio J, Doyle J, Alexander S, Gupta S, Punnett A. Impact of Ethnicity on Donor Search Results for Children Requiring Stem Cell Transplantation. J Pediatr Hematol Oncol. 2015 Apr; 37(3):e154-7. PMID: 25333838.
      View in: PubMed
    27. Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, Meier B, Gerstung M, Hong Y, Merino DM, Ramakrishna M, Remke M, Arnold R, Panigrahi GB, Thakkar NP, Hodel KP, Henninger EE, Göksenin AY, Bakry D, Charames GS, Druker H, Lerner-Ellis J, Mistry M, Dvir R, Grant R, Elhasid R, Farah R, Taylor GP, Nathan PC, Alexander S, Ben-Shachar S, Ling SC, Gallinger S, Constantini S, Dirks P, Huang A, Scherer SW, Grundy RG, Durno C, Aronson M, Gartner A, Meyn MS, Taylor MD, Pursell ZF, Pearson CE, Malkin D, Futreal PA, Stratton MR, Bouffet E, Hawkins C, Campbell PJ, Tabori U. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nat Genet. 2015 Mar; 47(3):257-62. PMID: 25642631.
      View in: PubMed
    28. Alexander S. Clinically defining and managing high-risk pediatric patients with acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program. 2014 Dec 05; 2014(1):181-9. PMID: 25696853.
      View in: PubMed
    29. Flank J, Thackray J, Nielson D, August A, Schechter T, Alexander S, Sung L, Dupuis LL. Olanzapine for treatment and prevention of acute chemotherapy-induced vomiting in children: a retrospective, multi-center review. Pediatr Blood Cancer. 2015 Mar; 62(3):496-501. PMID: 25328089.
      View in: PubMed
    30. Alexander S, Kraveka JM, Weitzman S, Lowe E, Smith L, Lynch JC, Chang M, Kinney MC, Perkins SL, Laver J, Gross TG, Weinstein H. Advanced stage anaplastic large cell lymphoma in children and adolescents: results of ANHL0131, a randomized phase III trial of APO versus a modified regimen with vinblastine: a report from the children's oncology group. Pediatr Blood Cancer. 2014 Dec; 61(12):2236-42. PMID: 25156886.
      View in: PubMed
    31. Shaikh F, Voicu L, Tole S, To T, Doria AS, Sung L, Alexander S. The risk of traumatic lumbar punctures in children with acute lymphoblastic leukaemia. Eur J Cancer. 2014 May; 50(8):1482-9. PMID: 24656342.
      View in: PubMed
    32. Kassam A, Skiadaresis J, Alexander S, Wolfe J. Parent and clinician preferences for location of end-of-life care: home, hospital or freestanding hospice? Pediatr Blood Cancer. 2014 May; 61(5):859-64. PMID: 24265171.
      View in: PubMed
    33. Kirwan C, Ngan BY, Halliday W, Alexander S, Ali A. Primary conjunctival anaplastic large cell lymphoma in a child. J AAPOS. 2013 Aug; 17(4):437-9. PMID: 23896363.
      View in: PubMed
    34. Rodrigues A, Wong C, Mattiussi A, Alexander S, Lau E, Dupuis LL. Methylnaltrexone for opioid-induced constipation in pediatric oncology patients. Pediatr Blood Cancer. 2013 Oct; 60(10):1667-70. PMID: 23766091.
      View in: PubMed
    35. Shaikh F, Brzezinski J, Alexander S, Arzola C, Carvalho JC, Beyene J, Sung L. Ultrasound imaging for lumbar punctures and epidural catheterisations: systematic review and meta-analysis. BMJ. 2013 Mar 26; 346:f1720. PMID: 23532866.
      View in: PubMed
    36. Kassam A, Skiadaresis J, Habib S, Alexander S, Wolfe J. Moving toward quality palliative cancer care: parent and clinician perspectives on gaps between what matters and what is accessible. J Clin Oncol. 2013 Mar 01; 31(7):910-5. PMID: 23182989.
      View in: PubMed
    37. Al Mahmoud R, Weitzman S, Schechter T, Ngan B, Abdelhaleem M, Alexander S. Peripheral T-cell lymphoma in children and adolescents: a single-institution experience. J Pediatr Hematol Oncol. 2012 Nov; 34(8):611-6. PMID: 23042011.
      View in: PubMed
    38. Diorio C, Tomlinson D, Boydell KM, Regier DA, Ethier MC, Alli A, Alexander S, Gassas A, Taylor J, Kellow C, Mills D, Sung L. Attitudes toward infection prophylaxis in pediatric oncology: a qualitative approach. PLoS One. 2012; 7(10):e47815. PMID: 23112849.
      View in: PubMed
    39. Shaikh F, Ngan BY, Alexander S, Grant R. Progressive transformation of germinal centers in children and adolescents: an intriguing cause of lymphadenopathy. Pediatr Blood Cancer. 2013 Jan; 60(1):26-30. PMID: 22707034.
      View in: PubMed
    40. Gupta S, Crump HL, Alexander S. The utility of end-of-treatment bone marrow aspirates in pediatric acute lymphoblastic leukemia: a quality improvement project. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1305-6. PMID: 22619044.
      View in: PubMed
    41. Sung L, Manji A, Beyene J, Dupuis LL, Alexander S, Phillips R, Lehrnbecher T. Fluoroquinolones in children with fever and neutropenia: a systematic review of prospective trials. Pediatr Infect Dis J. 2012 May; 31(5):431-5. PMID: 22189521.
      View in: PubMed
    42. Ethier MC, Alexander S, Abla O, Green G, Lam R, Sung L. Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia. Leuk Lymphoma. 2012 Sep; 53(9):1677-81. PMID: 22390648.
      View in: PubMed
    43. Blanco E, Beyene J, Maloney AM, Almeida R, Ethier MC, Winick N, Alexander S, Sung L. Non-relapse mortality in pediatric acute lymphoblastic leukemia: a systematic review and meta-analysis. Leuk Lymphoma. 2012 May; 53(5):878-85. PMID: 22066711.
      View in: PubMed
    44. Alexander S, Nieder M, Zerr DM, Fisher BT, Dvorak CC, Sung L. Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn? Pediatr Blood Cancer. 2012 Jul 15; 59(1):16-20. PMID: 22102612.
      View in: PubMed
    45. McCrone L, Alexander S, Karsli C, Taylor G, Amaral JG, Parra D, Temple M, John P, Connolly BL. US-guided percutaneous needle biopsy of anterior mediastinal masses in children. Pediatr Radiol. 2012 Jan; 42(1):40-9. PMID: 21863292.
      View in: PubMed
    46. Sung L, Yanofsky R, Klaassen RJ, Dix D, Pritchard S, Winick N, Alexander S, Klassen A. Quality of life during active treatment for pediatric acute lymphoblastic leukemia. Int J Cancer. 2011 Mar 01; 128(5):1213-20. PMID: 20473921.
      View in: PubMed
    47. Li S, Traubici J, Ethier MC, Gillmeister B, Alexander S, Gassas A, Sung L. Pneumatosis intestinalis in children with acute lymphoblastic leukemia and acute myeloid leukemia. Support Care Cancer. 2012 Feb; 20(2):343-7. PMID: 21234607.
      View in: PubMed
    48. Alexander S, Hopewell S, Hunter S, Chouksey A. Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis. J Pediatr Hematol Oncol. 2008 Jan; 30(1):93-5. PMID: 18176193.
      View in: PubMed
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