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Jason Maynes

TitleAnesthesiologist
InstitutionThe Hospital for Sick Children
DepartmentAnaesthesia
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Echaniz G, Chan V, Maynes JT, Jozaghi Y, Agur A. Ultrasound-guided maxillary nerve block: an anatomical study using the suprazygomatic approach. Can J Anaesth. 2019 Sep 23. PMID: 31549339.
      View in: PubMed
    2. Drost CC, Rovas A, Kusche-Vihrog K, Van Slyke P, Kim H, Hoang VC, Maynes JT, Wennmann DO, Pavenstädt H, Linke W, Lukasz A, Hesse B, Kümpers P. Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis. Thromb Haemost. 2019 Sep 07. PMID: 31493777.
      View in: PubMed
    3. Lokoff A, Maynes JT. The incidence, significance, and management of accidental intra-arterial injection: a narrative review. Can J Anaesth. 2019 May; 66(5):576-592. PMID: 30877587.
      View in: PubMed
    4. O'Leary JD, Janus M, Duku E, Wijeysundera DN, To T, Li P, Maynes JT, Faraoni D, Crawford MW. Influence of Surgical Procedures and General Anesthesia on Child Development Before Primary School Entry Among Matched Sibling Pairs. JAMA Pediatr. 2019 Jan 01; 173(1):29-36. PMID: 30398535.
      View in: PubMed
    5. Norris MJ, Malhi M, Duan W, Ouyang H, Granados A, Cen Y, Tseng YC, Gubbay J, Maynes J, Moraes TJ. Targeting Intracellular Ion Homeostasis for the Control of Respiratory Syncytial Virus. Am J Respir Cell Mol Biol. 2018 12; 59(6):733-744. PMID: 30095982.
      View in: PubMed
    6. Chatterjee D, Fatah M, Akdis D, Spears DA, Koopmann TT, Mittal K, Rafiq MA, Cattanach BM, Zhao Q, Healey JS, Ackerman MJ, Bos JM, Sun Y, Maynes JT, Brunckhorst C, Medeiros-Domingo A, Duru F, Saguner AM, Hamilton RM. An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis. Eur Heart J. 2018 11 21; 39(44):3932-3944. PMID: 30239670.
      View in: PubMed
    7. Selvadurai S, Maynes JT, McDonnell C, Cushing SL, Propst EJ, Lorenzo A, Lim A, Meltzer LJ, Lu Z, Horner RL, Narang I. Evaluating the effects of general anesthesia on sleep in children undergoing elective surgery: an observational case-control study. Sleep. 2018 08 01; 41(8). PMID: 29741674.
      View in: PubMed
    8. Traister A, Patel R, Huang A, Patel S, Plakhotnik J, Lee JE, Medina MG, Welsh C, Ruparel P, Zhang L, Friedberg M, Maynes J, Coles J. Cardiac regenerative capacity is age- and disease-dependent in childhood heart disease. PLoS One. 2018; 13(7):e0200342. PMID: 30044800.
      View in: PubMed
    9. Moran J, G Sanderson K, Maynes J, Vig A, Batmanabane V, Kannu P, Tavares E, Vincent A, Héon E. IFT80 mutations cause a novel complex ciliopathy phenotype with retinal degeneration. Clin Genet. 2018 10; 94(3-4):368-372. PMID: 29923190.
      View in: PubMed
    10. Wang L, Dou W, Malhi M, Zhu M, Liu H, Plakhotnik J, Xu Z, Zhao Q, Chen J, Chen S, Hamilton R, Simmons CA, Maynes JT, Sun Y. Microdevice Platform for Continuous Measurement of Contractility, Beating Rate, and Beating Rhythm of Human-Induced Pluripotent Stem Cell-Cardiomyocytes inside a Controlled Incubator Environment. ACS Appl Mater Interfaces. 2018 Jun 27; 10(25):21173-21183. PMID: 29874032.
      View in: PubMed
    11. Coghlan M, Richards E, Shaik S, Rossi P, Vanama RB, Ahmadi S, Petroz C, Crawford M, Maynes JT. Inhalational Anesthetics Induce Neuronal Protein Aggregation and Affect ER Trafficking. Sci Rep. 2018 03 27; 8(1):5275. PMID: 29588456.
      View in: PubMed
    12. Gutbier B, Jiang X, Dietert K, Ehrler C, Lienau J, Van Slyke P, Kim H, Hoang VC, Maynes JT, Dumont DJ, Gruber AD, Weissmann N, Mitchell TJ, Suttorp N, Witzenrath M. Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia. Crit Care. 2017 Nov 13; 21(1):274. PMID: 29132435.
      View in: PubMed
    13. Hogarth KA, Costford SR, Yoon G, Sondheimer N, Maynes JT. DNM1L Variant Alters Baseline Mitochondrial Function and Response to Stress in a Patient with Severe Neurological Dysfunction. Biochem Genet. 2018 Apr; 56(1-2):56-77. PMID: 29110115.
      View in: PubMed
    14. Wong BM, Keilman J, Zuccaro J, Kelly C, Maynes JT, Fish JS. Anesthetic Practices for Laser Rehabilitation of Pediatric Hypertrophic Burn Scars. J Burn Care Res. 2017 Jan/Feb; 38(1):e36-e41. PMID: 27532615.
      View in: PubMed
    15. O'Leary JD, Janus M, Duku E, Wijeysundera DN, To T, Li P, Maynes JT, Crawford MW. A Population-based Study Evaluating the Association between Surgery in Early Life and Child Development at Primary School Entry. Anesthesiology. 2016 08; 125(2):272-9. PMID: 27433745.
      View in: PubMed
    16. Vincent A, Ng J, Gerth-Kahlert C, Tavares E, Maynes JT, Wright T, Tiwari A, Tumber A, Li S, Hanson JV, Bahr A, MacDonald H, Bähr L, Westall C, Berger W, Cremers FP, den Hollander AI, Héon E. Biallelic Mutations in CRB1 Underlie Autosomal Recessive Familial Foveal Retinoschisis. Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2637-46. PMID: 27258436.
      View in: PubMed
    17. Vincent A, Audo I, Tavares E, Maynes JT, Tumber A, Wright T, Li S, Michiels C, Condroyer C, MacDonald H, Verdet R, Sahel JA, Hamel CP, Zeitz C, Héon E. Biallelic Mutations in GNB3 Cause a Unique Form of Autosomal-Recessive Congenital Stationary Night Blindness. Am J Hum Genet. 2016 05 05; 98(5):1011-1019. PMID: 27063057.
      View in: PubMed
    18. Traister A, Lu M, Coles JG, Maynes JT. Dataset of integrin-linked kinase protein: Protein interactions in cardiomyocytes identified by mass spectrometry. Data Brief. 2016 Jun; 7:1148-50. PMID: 27408918.
      View in: PubMed
    19. Sittampalam S, Eglen R, Ferguson S, Maynes JT, Olden K, Schrader L, Shelper T, Ferrer M. Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays? Assay Drug Dev Technol. 2015 Jun; 13(5):254-61. PMID: 26120951.
      View in: PubMed
    20. Vincent A, Forster N, Maynes JT, Paton TA, Billingsley G, Roslin NM, Ali A, Sutherland J, Wright T, Westall CA, Paterson AD, Marshall CR, Héon E. OTX2 mutations cause autosomal dominant pattern dystrophy of the retinal pigment epithelium. J Med Genet. 2014 Dec; 51(12):797-805. PMID: 25293953.
      View in: PubMed
    21. Traister A, Li M, Aafaqi S, Lu M, Arab S, Radisic M, Gross G, Guido F, Sherret J, Verma S, Slorach C, Mertens L, Hui W, Roy A, Delgado-Olguín P, Hannigan G, Maynes JT, Coles JG. Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function. Nat Commun. 2014 Sep 11; 5:4533. PMID: 25208486.
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    22. Zhu J, Ide H, Fu YY, Teichert AM, Kato H, Weisel RD, Maynes JT, Coles JG, Caldarone CA. Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2550-7. PMID: 25172325.
      View in: PubMed
    23. Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, Coles JG, Caldarone CA. Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins. J Thorac Cardiovasc Surg. 2014 Jul; 148(1):245-53. PMID: 24084286.
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    24. Skene-Arnold TD, Luu HA, Uhrig RG, De Wever V, Nimick M, Maynes J, Fong A, James MN, Trinkle-Mulcahy L, Moorhead GB, Holmes CF. Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. Biochem J. 2013 Feb 01; 449(3):649-59. PMID: 23088536.
      View in: PubMed
    25. Maynes JT, Luu HA, Cherney MM, Andersen RJ, Williams D, Holmes CF, James MN. Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins. J Mol Biol. 2006 Feb 10; 356(1):111-20. PMID: 16343532.
      View in: PubMed
    26. Maynes JT, Cherney MM, Qasim MA, Laskowski M, James MN. Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations. Acta Crystallogr D Biol Crystallogr. 2005 May; 61(Pt 5):580-8. PMID: 15858268.
      View in: PubMed
    27. Maynes JT, Perreault KR, Cherney MM, Luu HA, James MN, Holmes CF. Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding. J Biol Chem. 2004 Oct 08; 279(41):43198-206. PMID: 15280359.
      View in: PubMed
    28. Lamoureux JS, Maynes JT, Glover JN. Recognition of 5'-YpG-3' sequences by coupled stacking/hydrogen bonding interactions with amino acid residues. J Mol Biol. 2004 Jan 09; 335(2):399-408. PMID: 14672650.
      View in: PubMed
    29. Maynes JT, Garen C, Cherney MM, Newton G, Arad D, Av-Gay Y, Fahey RC, James MN. The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold. J Biol Chem. 2003 Nov 21; 278(47):47166-70. PMID: 12958317.
      View in: PubMed
    30. Holmes CF, Maynes JT, Perreault KR, Dawson JF, James MN. Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins. Curr Med Chem. 2002 Nov; 9(22):1981-9. PMID: 12369866.
      View in: PubMed
    31. Maynes JT, Bateman KS, Cherney MM, Das AK, Luu HA, Holmes CF, James MN. Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1. J Biol Chem. 2001 Nov 23; 276(47):44078-82. PMID: 11535607.
      View in: PubMed
    32. Maynes JT, Yuan RG, Snyder FF. Identification, expression, and characterization of Escherichia coli guanine deaminase. J Bacteriol. 2000 Aug; 182(16):4658-60. PMID: 10913105.
      View in: PubMed
    33. Maynes JT, Yuan RG, Phipps BM, Litster SA, Leung K, Snyder FF. Further refinement on the engineering of adenosine phosphorylase from purine nucleoside phosphorylase. Adv Exp Med Biol. 2000; 486:107-10. PMID: 11783463.
      View in: PubMed
    34. Maynes JT, Yam W, Jenuth JP, Gang Yuan R, Litster SA, Phipps BM, Snyder FF. Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase. Biochem J. 1999 Dec 01; 344 Pt 2:585-92. PMID: 10567244.
      View in: PubMed
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