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Martin Offringa

TitleSenior Scientist
InstitutionThe Hospital for Sick Children
DepartmentChild Health Evaluative Sciences
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
ORCID ORCID Icon0000-0002-4402-5299 Additional info
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    Collapse Biography 
    Collapse education and training
    Erasmus University, RotterdamMDMedicine
    Erasmus University, RotterdamPhDEpidemiology
    University of Amsterdam, AmsterdamNeonatology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Butcher NJ, Tricco AC, Offringa M, Moher D, Galica J. Training researchers in publication science: why, what, and how. J Clin Epidemiol. 2019 Aug 27. PMID: 31465843.
      View in: PubMed
    2. Orkin J, Chan CY, Fayed N, Lin JLL, Major N, Lim A, Peebles ER, Moretti ME, Soscia J, Sultan R, Willan AR, Offringa M, Guttmann A, Bartlett L, Kanani R, Culbert E, Hardy-Brown K, Gordon M, Perlmutar M, Cohen E. Complex care for kids Ontario: protocol for a mixed-methods randomised controlled trial of a population-level care coordination initiative for children with medical complexity. BMJ Open. 2019 Aug 01; 9(8):e028121. PMID: 31375613.
      View in: PubMed
    3. Joachim KC, Farid-Kapadia M, Butcher NJ, Chee-A-Tow A, Monsour A, Cohen E, Mahant S, Guttmann A, Offringa M. Core outcome set for children with neurological impairment and tube feeding. Dev Med Child Neurol. 2019 Aug 01. PMID: 31372989.
      View in: PubMed
    4. Hepburn CM, Gilpin A, Autmizguine J, Denburg A, Dupuis LL, Finkelstein Y, Gruenwoldt E, Ito S, Jong G', Lacaze-Masmonteil T, Levy D, Macleod S, P Miller S, Offringa M, Pinsk M, Power B, Rieder M, Litalien C. Improving paediatric medications: A prescription for Canadian children and youth. Paediatr Child Health. 2019 Aug; 24(5):333-339. PMID: 31379437.
      View in: PubMed
    5. Szatmari P, Offringa M, Butcher NJ, Monga S. Counting What Counts: The Case for Harmonized Outcomes in Child and Youth Mental Health Research. J Am Acad Child Adolesc Psychiatry. 2019 Jul; 58(7):656-658. PMID: 31229181.
      View in: PubMed
    6. Kelly LE, Richer L, Ali S, Plint AC, Poonai N, Freedman SB, Knisley L, Shimmin C, Hickes S, 't Jong GW, Pechlivanoglou P, Offringa M, Lacaze T, Klassen TP. Innovative approaches to investigator-initiated, multicentre paediatric clinical trials in Canada. BMJ Open. 2019 Jun 27; 9(6):e029024. PMID: 31253625.
      View in: PubMed
    7. Knaapen M, Hall NJ, van der Lee JH, Butcher NJ, Offringa M, Van Heurn EWE, Bakx R, Gorter RR. Establishing a core outcome set for treatment of uncomplicated appendicitis in children: study protocol for an international Delphi survey. BMJ Open. 2019 May 22; 9(5):e028861. PMID: 31123006.
      View in: PubMed
    8. Butcher NJ, Monsour A, Mew EJ, Szatmari P, Pierro A, Kelly LE, Farid-Kapadia M, Chee-A-Tow A, Saeed L, Monga S, Ungar W, Terwee CB, Vohra S, Fergusson D, Askie LM, Williamson PR, Chan AW, Moher D, Offringa M. Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT). Trials. 2019 Mar 06; 20(1):161. PMID: 30841935.
      View in: PubMed
    9. Butcher NJ, Mew EJ, Saeed L, Monsour A, Chee-A-Tow A, Chan AW, Moher D, Offringa M. Guidance for reporting outcomes in clinical trials: scoping review protocol. BMJ Open. 2019 02 19; 9(2):e023001. PMID: 30782872.
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    10. Onland W, Cools F, Kroon A, Rademaker K, Merkus MP, Dijk PH, van Straaten HL, Te Pas AB, Mohns T, Bruneel E, van Heijst AF, Kramer BW, Debeer A, Zonnenberg I, Marechal Y, Blom H, Plaskie K, Offringa M, van Kaam AH. Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. JAMA. 2019 01 29; 321(4):354-363. PMID: 30694322.
      View in: PubMed
    11. Monsour A, Mew EJ, Szatmari P, Patel S, Saeed L, Offringa M, Butcher NJ. Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol. BMJ Open. 2019 01 15; 9(1):e024191. PMID: 30782729.
      View in: PubMed
    12. Gibb ACN, Crosby MA, McDiarmid C, Urban D, Lam JYK, Wales PW, Brockel M, Raval M, Offringa M, Skarsgard ED, Wester T, Wong K, de Beer D, Nelson G, Brindle ME. Creation of an Enhanced Recovery After Surgery (ERAS) Guideline for neonatal intestinal surgery patients: a knowledge synthesis and consensus generation approach and protocol study. BMJ Open. 2018 12 09; 8(12):e023651. PMID: 30530586.
      View in: PubMed
    13. Guillot M, Offringa M, Lacaze-Masmonteil T, Thébaud B. Cell-based therapy for bronchopulmonary dysplasia in preterm infants 1. Can J Physiol Pharmacol. 2019 Mar; 97(3):232-234. PMID: 30290122.
      View in: PubMed
    14. Sadeghirad B, Florez ID, Chang Y, Forutan F, Zeraatkar D, Morgan RL, Shahid S, Bala MM, Beyene J, Offringa M, Adams-Webber T, Sherman PM, El-Gouhary E, Guyatt GH, Johnston BC. Comparative Effectiveness of Prophylactic Therapies for Necrotizing Enterocolitis in Preterm Infants: Protocol for a Network Meta-analysis of Randomized Trials. Int J Prev Med. 2018; 9:83. PMID: 30283615.
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    15. Yu AM, Balasubramanaiam B, Offringa M, Kelly LE. Reporting of interventions and "standard of care" control arms in pediatric clinical trials: a quantitative analysis. Pediatr Res. 2018 09; 84(3):393-398. PMID: 29899384.
      View in: PubMed
    16. Janssen Lok M, Miyake H, Hock A, Daneman A, Pierro A, Offringa M. Value of abdominal ultrasound in management of necrotizing enterocolitis: a systematic review and meta-analysis. Pediatr Surg Int. 2018 Jun; 34(6):589-612. PMID: 29721677.
      View in: PubMed
    17. Barker CIS, Standing JF, Kelly LE, Hanly Faught L, Needham AC, Rieder MJ, de Wildt SN, Offringa M. Pharmacokinetic studies in children: recommendations for practice and research. Arch Dis Child. 2018 07; 103(7):695-702. PMID: 29674514.
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    18. Kelly LE, Sinha Y, Barker CIS, Standing JF, Offringa M. Useful pharmacodynamic endpoints in children: selection, measurement, and next steps. Pediatr Res. 2018 06; 83(6):1095-1103. PMID: 29667952.
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    19. Groothoff JW, Offringa M, Grootenhuis M, Jager KJ. Long-term consequences of renal insufficiency in children: lessons learned from the Dutch LERIC study. Nephrol Dial Transplant. 2018 04 01; 33(4):552-560. PMID: 28992218.
      View in: PubMed
    20. Woods H, Oronsaye E, Bali A, Rajakulasingam Y, Lee T, Umali N, Cohen E, Finkelstein Y, Offringa M, Persaud N. Development of a provisional essential medicines list for children in Canada: consensus process. CMAJ Open. 2018 Mar 26; 6(1):E146-E150. PMID: 29592851.
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    21. Ardell S, Offringa M, Ovelman C, Soll R. Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates. Cochrane Database Syst Rev. 2018 02 05; 2:CD008342. PMID: 29401369.
      View in: PubMed
    22. Puligandla PS, Skarsgard ED, Offringa M, Adatia I, Baird R, Bailey M, Brindle M, Chiu P, Cogswell A, Dakshinamurti S, Flageole H, Keijzer R, McMillan D, Oluyomi-Obi T, Pennaforte T, Perreault T, Piedboeuf B, Riley SP, Ryan G, Synnes A, Traynor M. Diagnosis and management of congenital diaphragmatic hernia: a clinical practice guideline. CMAJ. 2018 01 29; 190(4):E103-E112. PMID: 29378870.
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    23. Gorter RR, van der Lee JH, Heijsters FACJ, Cense HA, Bakx R, Kneepkens CMF, Wijnen MH, van der Steeg AFW, In't Hof KH, Offringa M, Heij HA. Outcome of initially nonoperative treatment for acute simple appendicitis in children. J Pediatr Surg. 2018 Sep; 53(9):1849-1854. PMID: 29395151.
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    24. Potter BK, Hutton B, Clifford TJ, Pallone N, Smith M, Stockler S, Chakraborty P, Barbeau P, Garritty CM, Pugliese M, Rahman A, Skidmore B, Tessier L, Tingley K, Coyle D, Greenberg CR, Korngut L, MacKenzie A, Mitchell JJ, Nicholls S, Offringa M, Schulze A, Taljaard M. Establishing core outcome sets for phenylketonuria (PKU) and medium-chain Acyl-CoA dehydrogenase (MCAD) deficiency in children: study protocol for systematic reviews and Delphi surveys. Trials. 2017 Dec 19; 18(1):603. PMID: 29258568.
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    25. Tedesco D, Farid-Kapadia M, Offringa M, Bhutta ZA, Maldonado Y, Ioannidis JPA, Contopoulos-Ioannidis DG. Comparative evidence on harms in pediatric randomized clinical trials from less developed versus more developed countries is limited. J Clin Epidemiol. 2018 03; 95:63-72. PMID: 29191447.
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    26. Costain G, Moore AM, Munroe L, Williams A, Zlotnik Shaul R, Rockman-Greenberg C, Offringa M, Kannu P. Enzyme replacement therapy in perinatal hypophosphatasia: Case report of a negative outcome and lessons for clinical practice. Mol Genet Metab Rep. 2018 Mar; 14:22-26. PMID: 29159075.
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    27. Rokhsefat S, Morra DE, Offringa M, Askie LM, Kelly LE. Trial registration in pediatric surgery trials. J Pediatr Surg. 2018 Jul; 53(7):1273-1279. PMID: 29150369.
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    28. Kelly LE, Caswell K, Short MA, Parimi PS, Offringa M, Diacovo T. Response biomarkers in neonatal intervention studies. Pediatr Res. 2018 02; 83(2):425-430. PMID: 29278643.
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    29. Onland W, Offringa M, van Kaam A. Late (= 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev. 2017 08 24; 8:CD002311. PMID: 28836266.
      View in: PubMed
    30. Hall NJ, Eaton S, Abbo O, Arnaud AP, Beaudin M, Brindle M, Bütter A, Davies D, Jancelewicz T, Johnson K, Keijzer R, Lapidus-Krol E, Offringa M, Piché N, Rintala R, Skarsgard E, Svensson JF, Ungar WJ, Wester T, Willan AR, Zani A, St Peter SD, Pierro A. Appendectomy versus non-operative treatment for acute uncomplicated appendicitis in children: study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial. BMJ Paediatr Open. 2017; 1(1). PMID: 29637088.
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    31. Farid-Kapadia M, Joachim KC, Balasingham C, Clyburne-Sherin A, Offringa M. Are child-centric aspects in newborn and child health systematic review and meta-analysis protocols and reports adequately reported?-two systematic reviews. Syst Rev. 2017 03 06; 6(1):31. PMID: 28260528.
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    32. Farid-Kapadia M, Askie L, Hartling L, Contopoulos-Ioannidis D, Bhutta ZA, Soll R, Moher D, Offringa M. Do systematic reviews on pediatric topics need special methodological considerations? BMC Pediatr. 2017 03 06; 17(1):57. PMID: 28260530.
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    33. Offringa M, Newton R, Cozijnsen MA, Nevitt SJ. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2017 02 22; 2:CD003031. PMID: 28225210.
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    34. Onland W, De Jaegere AP, Offringa M, van Kaam A. Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev. 2017 01 31; 1:CD010941. PMID: 28141913.
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    35. Kelly LE, Ito S, Woods D, Nunn AJ, Taketomo C, de Hoog M, Offringa M. A Comprehensive List of Items to be Included on a Pediatric Drug Monograph. J Pediatr Pharmacol Ther. 2017 Jan-Feb; 22(1):48-59. PMID: 28337081.
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    36. Kelly LE, Jansson LM, Moulsdale W, Pereira J, Simpson S, Guttman A, Allegaert K, Askie L, Roukema H, Lacaze T, Davis JM, Finnegan L, Williamson P, Offringa M. A core outcome set for neonatal abstinence syndrome: study protocol for a systematic review, parent interviews and a Delphi survey. Trials. 2016 11 08; 17(1):536. PMID: 27821184.
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    37. van der Zanden TM, de Wildt SN, Liem Y, Offringa M, de Hoog M. Developing a paediatric drug formulary for the Netherlands. Arch Dis Child. 2017 04; 102(4):357-361. PMID: 27799154.
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    38. Kapadia MZ, Joachim KC, Balasingham C, Cohen E, Mahant S, Nelson K, Maguire JL, Guttmann A, Offringa M. A Core Outcome Set for Children With Feeding Tubes and Neurologic Impairment: A Systematic Review. Pediatrics. 2016 07; 138(1). PMID: 27365302.
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    39. De Jaegere AP, Deurloo EE, van Rijn RR, Offringa M, van Kaam AH. Individualized lung recruitment during high-frequency ventilation in preterm infants is not associated with lung hyperinflation and air leaks. Eur J Pediatr. 2016 Aug; 175(8):1085-90. PMID: 27325148.
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    40. Kapadia MZ, Askie L, Hartling L, Contopoulos-Ioannidis D, Bhutta ZA, Soll R, Moher D, Offringa M. PRISMA-Children (C) and PRISMA-Protocol for Children (P-C) Extensions: a study protocol for the development of guidelines for the conduct and reporting of systematic reviews and meta-analyses of newborn and child health research. BMJ Open. 2016 Apr 18; 6(4):e010270. PMID: 27091820.
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    41. Kelly LE, Davies EH, Saint-Raymond A, Tomasi P, Offringa M. Important issues in the justification of a control treatment in paediatric drug trials. Arch Dis Child. 2016 Oct; 101(10):962-7. PMID: 27052950.
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    42. Askie L, Offringa M. Systematic reviews and meta-analysis. Semin Fetal Neonatal Med. 2015 Dec; 20(6):403-9. PMID: 26515266.
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    43. Jansen-van der Weide MC, Caldwell PH, Young B, de Vries MC, Willems DL, Van't Hoff W, Woolfall K, van der Lee JH, Offringa M. Clinical Trial Decisions in Difficult Circumstances: Parental Consent Under Time Pressure. Pediatrics. 2015 Oct; 136(4):e983-92. PMID: 26416935.
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    44. Clyburne-Sherin AV, Thurairajah P, Kapadia MZ, Sampson M, Chan WW, Offringa M. Recommendations and evidence for reporting items in pediatric clinical trial protocols and reports: two systematic reviews. Trials. 2015 Sep 18; 16:417. PMID: 26385379.
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    45. Offringa M, Davis JM, Turner MA, Ward R, Bax R, Maldonado S, Sinha V, McCune SK, Zajicek A, Benjamin DK, Bucci-Rechtweg C, Nelson RM. Applying Regulatory Science to Develop Safe and Effective Medicines for Neonates: Report of the US Food and Drug Administration First Annual Neonatal Scientific Workshop, October 28-29, 2014. Ther Innov Regul Sci. 2015 Sep; 49(5):623-631. PMID: 30227031.
      View in: PubMed
    46. Pullenayegum EM, Platt RW, Barwick M, Feldman BM, Offringa M, Thabane L. Knowledge translation in biostatistics: a survey of current practices, preferences, and barriers to the dissemination and uptake of new statistical methods. Stat Med. 2016 Mar 15; 35(6):805-18. PMID: 26307183.
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    47. Patel N, Ram D, Swiderska N, Mewasingh LD, Newton RW, Offringa M. Febrile seizures. BMJ. 2015 Aug 18; 351:h4240. PMID: 26286537.
      View in: PubMed
    48. Hall NJ, Kapadia MZ, Eaton S, Chan WW, Nickel C, Pierro A, Offringa M. Outcome reporting in randomised controlled trials and meta-analyses of appendicitis treatments in children: a systematic review. Trials. 2015 Jun 17; 16:275. PMID: 26081254.
      View in: PubMed
    49. Fernandes RM, Plint AC, Terwee CB, Sampaio C, Klassen TP, Offringa M, van der Lee JH. Validity of bronchiolitis outcome measures. Pediatrics. 2015 Jun; 135(6):e1399-408. PMID: 25986025.
      View in: PubMed
    50. Cools F, Offringa M, Askie LM. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2015 Mar 19; (3):CD000104. PMID: 25785789.
      View in: PubMed
    51. Gorter RR, van der Lee JH, Cense HA, Kneepkens CM, Wijnen MH, In 't Hof KH, Offringa M, Heij HA. Initial antibiotic treatment for acute simple appendicitis in children is safe: Short-term results from a multicenter, prospective cohort study. Surgery. 2015 May; 157(5):916-23. PMID: 25791031.
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    52. Needham AC, Kapadia MZ, Offringa M. Ethics review of pediatric multi-center drug trials. Paediatr Drugs. 2015 Feb; 17(1):23-30. PMID: 25354988.
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    53. Van't Hoff W, Offringa M. StaR Child Health: developing evidence-based guidance for the design, conduct and reporting of paediatric trials. Arch Dis Child. 2015 Feb; 100(2):189-92. PMID: 25260517.
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    54. Hulzebos CV, Dijk PH, van Imhoff DE, Bos AF, Lopriore E, Offringa M, Ruiter SA, van Braeckel KN, Krabbe PF, Quik EH, van Toledo-Eppinga L, Nuytemans DH, van Wassenaer-Leemhuis AG, Benders MJ, Korbeeck-van Hof KK, van Lingen RA, Groot Jebbink LJ, Liem D, Mansvelt P, Buijs J, Govaert P, van Vliet I, Mulder TL, Wolfs C, Fetter WP, Laarman C. The bilirubin albumin ratio in the management of hyperbilirubinemia in preterm infants to improve neurodevelopmental outcome: a randomized controlled trial--BARTrial. PLoS One. 2014; 9(6):e99466. PMID: 24927259.
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    55. Onland W, Debray TP, Laughon MM, Miedema M, Cools F, Askie LM, Asselin JM, Calvert SA, Courtney SE, Dani C, Durand DJ, Marlow N, Peacock JL, Pillow JJ, Soll RF, Thome UH, Truffert P, Schreiber MD, Van Reempts P, Vendettuoli V, Vento G, van Kaam AH, Moons KG, Offringa M. Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study. BMC Pediatr. 2013 Dec 17; 13:207. PMID: 24345305.
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    56. Schoenmaker NJ, Haverman L, Tromp WF, van der Lee JH, Offringa M, Adams B, Bouts AH, Collard L, Cransberg K, van Dyck M, Godefroid N, van Hoeck K, Koster-Kamphuis L, Lilien MR, Raes A, Taylan C, Grootenhuis MA, Groothoff JW. Children of non-Western origin with end-stage renal disease in the Netherlands, Belgium and a part of Germany have impaired health-related quality of life compared with Western children. Nephrol Dial Transplant. 2014 Feb; 29(2):448-57. PMID: 24235076.
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    57. Offringa M, Needham AC, Chan WW. StaR Child Health: improving global standards for child health research. Early Hum Dev. 2013 Nov; 89(11):861-4. PMID: 24113210.
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    58. Schoenmaker NJ, Tromp WF, van der Lee JH, Offringa M, Craig JC, Groothoff JW. Quality and consistency of clinical practice guidelines for the management of children on chronic dialysis. Nephrol Dial Transplant. 2013 Dec; 28(12):3052-61. PMID: 24097802.
      View in: PubMed
    59. Offringa M, Newton R. Prophylactic drug management for febrile seizures in children (Review). Evid Based Child Health. 2013 Jul; 8(4):1376-485. PMID: 23877946.
      View in: PubMed
    60. de Kluiver E, Offringa M, Walther FJ, Duvekot JJ, de Laat MW. [Perinatal policy in cases of extreme prematurity; an investigation into the implementation of the guidelines]. Ned Tijdschr Geneeskd. 2013; 157(38):A6362. PMID: 24050448.
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    61. van Laerhoven H, de Haan TR, Offringa M, Post B, van der Lee JH. Prognostic tests in term neonates with hypoxic-ischemic encephalopathy: a systematic review. Pediatrics. 2013 Jan; 131(1):88-98. PMID: 23248219.
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    62. Wittmeier KD, Craig J, Klassen TP, Offringa M. The mission of StaR Child Health is to improve the quality of the design, conduct, and reporting of pediatric clinical research by promoting the use of modern research standards. Introduction. Pediatrics. 2012 Jun; 129 Suppl 3:S111. PMID: 22661755.
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    63. Hartling L, Wittmeier KD, Caldwell P, van der Lee H, Klassen TP, Craig JC, Offringa M. StaR child health: developing evidence-based guidance for the design, conduct, and reporting of pediatric trials. Pediatrics. 2012 Jun; 129 Suppl 3:S112-7. PMID: 22661756.
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    64. Caldwell PH, Dans L, de Vries MC, Newman Ba Hons J, Sammons H, Spriggs M Bioeth M, Tambe P, Van't Hoff W, Woolfall K, Young B, Offringa M. Standard 1: consent and recruitment. Pediatrics. 2012 Jun; 129 Suppl 3:S118-23. PMID: 22661757.
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    65. Hartling L, Hamm M, Klassen T, Chan AW, Meremikwu M, Moyer V, Scott S, Moher D, Offringa M. Standard 2: containing risk of bias. Pediatrics. 2012 Jun; 129 Suppl 3:S124-31. PMID: 22661758.
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    66. Ellenberg S, Fernandes RM, Saloojee H, Bassler D, Askie L, Vandermeer B, Offringa M, Van der Tweel I, Altman DG, van der Lee JH. Standard 3: data monitoring committees. Pediatrics. 2012 Jun; 129 Suppl 3:S132-7. PMID: 22661759.
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    67. van der Tweel I, Askie L, Vandermeer B, Ellenberg S, Fernandes RM, Saloojee H, Bassler D, Altman DG, Offringa M, van der Lee JH. Standard 4: determining adequate sample sizes. Pediatrics. 2012 Jun; 129 Suppl 3:S138-45. PMID: 22661760.
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    68. Sinha IP, Altman DG, Beresford MW, Boers M, Clarke M, Craig J, Alberighi OD, Fernandes RM, Hartling L, Johnston BC, Lux A, Plint A, Tugwell P, Turner M, van der Lee JH, Offringa M, Williamson PR, Smyth RL. Standard 5: selection, measurement, and reporting of outcomes in clinical trials in children. Pediatrics. 2012 Jun; 129 Suppl 3:S146-52. PMID: 22661761.
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    69. de Haan TR, Bijleveld YA, van der Lee JH, Groenendaal F, van den Broek MP, Rademaker CM, van Straaten HL, van Weissenbruch MM, Vermeulen JR, Dijk PH, Dudink J, Rijken M, van Heijst A, Dijkman KP, Gavilanes D, van Kaam AH, Offringa M, Mathôt RA. Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study. BMC Pediatr. 2012 May 22; 12:45. PMID: 22515424.
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    70. Onland W, Offringa M, van Kaam A. Late (= 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev. 2012 Apr 18; (4):CD002311. PMID: 22513906.
      View in: PubMed
    71. Offringa M, Newton R. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2012 Apr 18; (4):CD003031. PMID: 22513908.
      View in: PubMed
    72. Onland W, Offringa M, Cools F, De Jaegere AP, Rademaker K, Blom H, Cavatorta E, Debeer A, Dijk PH, van Heijst AF, Kramer BW, Kroon AA, Mohns T, van Straaten HL, te Pas AB, Theyskens C, van Weissenbruch MM, van Kaam AH. Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trial. BMC Pediatr. 2011 Nov 09; 11:102. PMID: 22070744.
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    73. Hartling L, Wittmeier KD, Caldwell PH, van der Lee JH, Klassen TP, Craig JC, Offringa M. StaR Child Health: developing evidence-based guidance for the design, conduct, and reporting of pediatric trials. Clin Pharmacol Ther. 2011 Nov; 90(5):727-31. PMID: 21993427.
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    74. Tromp WF, Schoenmaker NJ, van der Lee JH, Adams B, Bouts AH, Collard L, Cransberg K, Van Damme-Lombaerts R, Godefroid N, van Hoeck K, Koster-Kamphuis L, Lilien MR, Raes A, Offringa M, Groothoff JW. Important differences in management policies for children with end-stage renal disease in the Netherlands and Belgium--report from the RICH-Q study. Nephrol Dial Transplant. 2012 May; 27(5):1984-92. PMID: 21976739.
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    75. de Ru MH, Boelens JJ, Das AM, Jones SA, van der Lee JH, Mahlaoui N, Mengel E, Offringa M, O'Meara A, Parini R, Rovelli A, Sykora KW, Valayannopoulos V, Vellodi A, Wynn RF, Wijburg FA. Enzyme replacement therapy and/or hematopoietic stem cell transplantation at diagnosis in patients with mucopolysaccharidosis type I: results of a European consensus procedure. Orphanet J Rare Dis. 2011 Aug 10; 6:55. PMID: 21831279.
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    76. Tromp WF, van der Lee JH, Offringa M, Bouts AH, Collard L, Cransberg K, Van Damme-Lombaerts R, Godefroid N, Van Hoeck K, Koster-Kamphuis L, Lilien MR, Raes A, Groothoff JW. Lessons learned from efforts to improve the quality of care in children with end-stage renal disease in the Netherlands and Belgium. Arch Dis Child. 2011 Dec; 96(12):1093-6. PMID: 21798874.
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    77. Fernandes RM, van der Lee JH, Offringa M. Data monitoring committees, interim analysis and early termination in paediatric trials. Acta Paediatr. 2011 Oct; 100(10):1386-92. PMID: 21434998.
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    78. de Winter JP, Joosten KF, Ijland MM, Verkade HJ, Offringa M, Dorrius MD, van Hasselt PM. [New Dutch practice guideline for administration of vitamin K to full-term newborns]. Ned Tijdschr Geneeskd. 2011; 155(18):A936. PMID: 21672291.
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    79. Offringa M, van der Lee H. Small sample approach, and statistical and epidemiological aspects. Handb Exp Pharmacol. 2011; 205:181-202. PMID: 21882112.
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    80. Kemper EM, Merkus M, Wierenga PC, Van Rijn PC, Van der Werff D, Lie-A-Huen L, Offringa M. Towards evidence-based pharmacotherapy in children. Paediatr Anaesth. 2011 Mar; 21(3):183-9. PMID: 21199133.
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    81. Onland W, van Kaam AH, De Jaegere AP, Offringa M. Open-label glucocorticoids modulate dexamethasone trial results in preterm infants. Pediatrics. 2010 Oct; 126(4):e954-64. PMID: 20837588.
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    82. Weijenberg A, Offringa M, Brouwer OF, Callenbach PM. RCTs with new antiepileptic drugs in children: a systematic review of monotherapy studies and their methodology. Epilepsy Res. 2010 Sep; 91(1):1-9. PMID: 20674277.
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    83. Onland W, de Laat MW, Mol BW, Offringa M. Effects of antenatal corticosteroids given prior to 26 weeks' gestation: a systematic review of randomized controlled trials. Am J Perinatol. 2011 Jan; 28(1):33-44. PMID: 20648416.
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    84. Cools F, Askie LM, Offringa M, Asselin JM, Calvert SA, Courtney SE, Dani C, Durand DJ, Gerstmann DR, Henderson-Smart DJ, Marlow N, Peacock JL, Pillow JJ, Soll RF, Thome UH, Truffert P, Schreiber MD, Van Reempts P, Vendettuoli V, Vento G. Elective high-frequency oscillatory versus conventional ventilation in preterm infants: a systematic review and meta-analysis of individual patients' data. Lancet. 2010 Jun 12; 375(9731):2082-91. PMID: 20552718.
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    85. Israëls J, Frakking FN, Kremer LC, Offringa M, Kuijpers TW, van de Wetering MD. Mannose-binding lectin and infection risk in newborns: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2010 Nov; 95(6):F452-61. PMID: 20488866.
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    86. de Laat MW, Wiegerinck MM, Walther FJ, Boluyt N, Mol BW, van der Post JA, van Lith JM, Offringa M. [Practice guideline 'Perinatal management of extremely preterm delivery']. Ned Tijdschr Geneeskd. 2010; 154:A2701. PMID: 21429260.
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    87. Fernandes RM, van der Lee JH, Offringa M. A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials. BMC Pediatr. 2009 Dec 13; 9:77. PMID: 20003383.
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    88. Tabbers MM, Boluyt N, Offringa M. Implementation of an evidence-based guideline on fluid resuscitation: lessons learnt for future guidelines. Eur J Pediatr. 2010 Jun; 169(6):749-58. PMID: 19937452.
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    89. Klassen TP, Hartling L, Hamm M, van der Lee JH, Ursum J, Offringa M. StaR Child Health: an initiative for RCTs in children. Lancet. 2009 Oct 17; 374(9698):1310-2. PMID: 19837237.
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    90. van der Lee JH, Wesseling J, Tanck MW, Offringa M. Sequential design with boundaries approach in pediatric intervention research reduces sample size. J Clin Epidemiol. 2010 Jan; 63(1):19-27. PMID: 19788954.
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    91. Cools F, Henderson-Smart DJ, Offringa M, Askie LM. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2009 Jul 08; (3):CD000104. PMID: 19588317.
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    92. Cools F, Askie LM, Offringa M. Elective high-frequency oscillatory ventilation in preterm infants with respiratory distress syndrome: an individual patient data meta-analysis. BMC Pediatr. 2009 May 16; 9:33. PMID: 19445701.
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    93. van der Starre C, van den Bos-Boon A, van der Tuijn Y, Maas I, Molendijk AH, Offringa M, Vreede WT, Tibboel D. [Multidisciplinary care of patient's safety at the child intensive care]. Ned Tijdschr Geneeskd. 2009 Feb 21; 153(8):334-9. PMID: 19294936.
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    94. Weber EH, Timmermans IT, Offringa M. The Dutch Medicines for Children Research Network: a new resource for clinical trials. Paediatr Drugs. 2009; 11(3):161-3. PMID: 19445544.
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    95. Onland W, Offringa M, De Jaegere AP, van Kaam AH. Finding the optimal postnatal dexamethasone regimen for preterm infants at risk of bronchopulmonary dysplasia: a systematic review of placebo-controlled trials. Pediatrics. 2009 Jan; 123(1):367-77. PMID: 19117904.
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    96. van der Lee JH, Offringa M. [Start of reliable pediatric clinical research]. Ned Tijdschr Geneeskd. 2009; 153:A1310. PMID: 19900330.
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    97. van der Lee JH, Tanck MW, Wesseling J, Offringa M. Pitfalls in the design and analysis of paediatric clinical trials: a case of a 'failed' multi-centre study, and potential solutions. Acta Paediatr. 2009 Feb; 98(2):385-91. PMID: 18826493.
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    98. Klassen TP, Hartling L, Craig JC, Offringa M. Children are not just small adults: the urgent need for high-quality trial evidence in children. PLoS Med. 2008 Aug 12; 5(8):e172. PMID: 18700813.
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    99. Onland W, De Jaegere AP, Offringa M, van Kaam AH. Effects of higher versus lower dexamethasone doses on pulmonary and neurodevelopmental sequelae in preterm infants at risk for chronic lung disease: a meta-analysis. Pediatrics. 2008 Jul; 122(1):92-101. PMID: 18595991.
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    100. Brand PL, Offringa M. [Serious concerns regarding research linking cot death with child day care]. Ned Tijdschr Geneeskd. 2008 Jun 14; 152(24):1361-4. PMID: 18664212.
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    101. Fernandes R, van der Lee JH, Twisk JW, Offringa M. Design, analysis and reporting on a croup trial: a reply to Chub-Uppakarn s et al. Int J Pediatr Otorhinolaryngol. 2008 Aug; 72(8):1288-9; author reply 1290. PMID: 18538420.
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    102. Mokkink LB, van der Lee JH, Grootenhuis MA, Offringa M, Heymans HS. Defining chronic diseases and health conditions in childhood (0-18 years of age): national consensus in the Netherlands. Eur J Pediatr. 2008 Dec; 167(12):1441-7. PMID: 18340463.
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    103. van der Lee JH, Wesseling J, Tanck MW, Offringa M. Efficient ways exist to obtain the optimal sample size in clinical trials in rare diseases. J Clin Epidemiol. 2008 Apr; 61(4):324-30. PMID: 18313556.
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    104. Boluyt N, Tjosvold L, Lefebvre C, Klassen TP, Offringa M. Usefulness of systematic review search strategies in finding child health systematic reviews in MEDLINE. Arch Pediatr Adolesc Med. 2008 Feb; 162(2):111-6. PMID: 18250233.
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    105. Boluyt N, van der Lee JH, Moyer VA, Brand PL, Offringa M. State of the evidence on acute asthma management in children: a critical appraisal of systematic reviews. Pediatrics. 2007 Dec; 120(6):1334-43. PMID: 18055684.
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    106. Ankum WM, Reitsma JB, Offringa M. IVF with preimplantation genetic screening, a promising new treatment with unexpectedly negative health outcomes: the Hippocratic role of Data Monitoring Committees. Hum Reprod. 2008 Jan; 23(1):1-3. PMID: 18029343.
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    107. van de Wetering MD, Weggelaar N, Offringa M, Caron HN, Kuijpers TW. Granulocyte transfusions in neutropaenic children: a systematic review of the literature. Eur J Cancer. 2007 Sep; 43(14):2082-92. PMID: 17761413.
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    108. Frakking FN, Brouwer N, van Eijkelenburg NK, Merkus MP, Kuijpers TW, Offringa M, Dolman KM. Low mannose-binding lectin (MBL) levels in neonates with pneumonia and sepsis. Clin Exp Immunol. 2007 Nov; 150(2):255-62. PMID: 17711490.
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    109. Henderson-Smart DJ, Cools F, Bhuta T, Offringa M. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2007 Jul 18; (3):CD000104. PMID: 17636590.
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    110. van der Lee JH, Mokkink LB, Grootenhuis MA, Heymans HS, Offringa M. Definitions and measurement of chronic health conditions in childhood: a systematic review. JAMA. 2007 Jun 27; 297(24):2741-51. PMID: 17595275.
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    111. Boluyt N, Bollen CW, Bos AP, Kok JH, von Rosenstiel IA, Offringa M. [The practice guideline 'Volume suppletion in critically-ill neonates and children up to the age of 18 years' of the Dutch Paediatric Association]. Ned Tijdschr Geneeskd. 2006 Nov 04; 150(44):2421-6. PMID: 17131700.
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    112. Frakking FN, Brouwer N, Zweers D, Merkus MP, Kuijpers TW, Offringa M, Dolman KM. High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. Clin Exp Immunol. 2006 Jul; 145(1):5-12. PMID: 16792667.
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    113. Boluyt N, van Kempen A, Offringa M. Neurodevelopment after neonatal hypoglycemia: a systematic review and design of an optimal future study. Pediatrics. 2006 Jun; 117(6):2231-43. PMID: 16740869.
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    114. Boluyt N, Bollen CW, Bos AP, Kok JH, Offringa M. Fluid resuscitation in neonatal and pediatric hypovolemic shock: a Dutch Pediatric Society evidence-based clinical practice guideline. Intensive Care Med. 2006 Jul; 32(7):995-1003. PMID: 16791662.
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    115. de Waal KA, Baerts W, Offringa M. Systematic review of the optimal fluid for dilutional exchange transfusion in neonatal polycythaemia. Arch Dis Child Fetal Neonatal Ed. 2006 Jan; 91(1):F7-10. PMID: 16371393.
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    116. van de Wetering MD, de Witte MA, Kremer LC, Offringa M, Scholten RJ, Caron HN. Efficacy of oral prophylactic antibiotics in neutropenic afebrile oncology patients: a systematic review of randomised controlled trials. Eur J Cancer. 2005 Jul; 41(10):1372-82. PMID: 15913983.
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    117. Boluyt N, Lincke CR, Offringa M. Quality of evidence-based pediatric guidelines. Pediatrics. 2005 May; 115(5):1378-91. PMID: 15867050.
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    118. Cools F, Offringa M. Neuromuscular paralysis for newborn infants receiving mechanical ventilation. Cochrane Database Syst Rev. 2005 Apr 18; (2):CD002773. PMID: 15846639.
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    119. Groothoff JW, Grootenhuis MA, Offringa M, Stronks K, Hutten GJ, Heymans HS. Social consequences in adult life of end-stage renal disease in childhood. J Pediatr. 2005 Apr; 146(4):512-7. PMID: 15812455.
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    120. Brand PL, Engelbert RH, Helders PJ, Offringa M. [Systematic review of the effects of therapy in infants with the KISS-syndrome (kinetic imbalance due to suboccipital strain)]. Ned Tijdschr Geneeskd. 2005 Mar 26; 149(13):703-7. PMID: 15819137.
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    121. Groothoff J, Gruppen M, de Groot E, Offringa M. Cardiovascular disease as a late complication of end-stage renal disease in children. Perit Dial Int. 2005 Feb; 25 Suppl 3:S123-6. PMID: 16048276.
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    122. van Karnebeek CD, Jansweijer MC, Leenders AG, Offringa M, Hennekam RC. Diagnostic investigations in individuals with mental retardation: a systematic literature review of their usefulness. Eur J Hum Genet. 2005 Jan; 13(1):6-25. PMID: 15523501.
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    123. Groothoff JW, Cransberg K, Offringa M, van de Kar NJ, Lilien MR, Davin JC, Heymans HS. Long-term follow-up of renal transplantation in children: a Dutch cohort study. Transplantation. 2004 Aug 15; 78(3):453-60. PMID: 15316376.
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    124. Heij HA, Offringa M. Effect of an imaging protocol on clinical outcomes among pediatric patients with appendicitis. Pediatrics. 2004 Mar; 113(3 Pt 1):626. PMID: 14993563.
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    125. Assendelf WJ, Scholten RJ, Offringa M. Pneumococcal vaccination for the elderly in The Netherlands? Assessment of the quality and content of available comparative studies. Neth J Med. 2004 Feb; 62(2):36-44. PMID: 15127829.
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    126. Boluyt N, Scholten RJ, Offringa M. [The practice of systematic reviews. XI. The Cochrane Library]. Ned Tijdschr Geneeskd. 2003 Dec 27; 147(52):2572-7. PMID: 14723024.
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    127. van Santen HM, Vulsma T, Dijkgraaf MG, Blumer RM, Heinen R, Jaspers MW, Geenen MM, Offringa MO, de Vijlder JJ, van den Bos C. No damaging effect of chemotherapy in addition to radiotherapy on the thyroid axis in young adult survivors of childhood cancer. J Clin Endocrinol Metab. 2003 Aug; 88(8):3657-63. PMID: 12915651.
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    128. Gruppen MP, Groothoff JW, Prins M, van der Wouw P, Offringa M, Bos WJ, Davin JC, Heymans HS. Cardiac disease in young adult patients with end-stage renal disease since childhood: a Dutch cohort study. Kidney Int. 2003 Mar; 63(3):1058-65. PMID: 12631088.
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    129. Groothoff JW, Grootenhuis MA, Offringa M, Gruppen MP, Korevaar JC, Heymans HS. Quality of life in adults with end-stage renal disease since childhood is only partially impaired. Nephrol Dial Transplant. 2003 Feb; 18(2):310-7. PMID: 12543886.
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    130. Henderson-Smart DJ, Bhuta T, Cools F, Offringa M. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2003; (4):CD000104. PMID: 14583909.
      View in: PubMed
    131. Groothoff JW, Offringa M, Van Eck-Smit BL, Gruppen MP, Van De Kar NJ, Wolff ED, Lilien MR, Davin JC, Heymans HS, Dekker FW. Severe bone disease and low bone mineral density after juvenile renal failure. Kidney Int. 2003 Jan; 63(1):266-75. PMID: 12472792.
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    132. Olde Scholtenhuis MA, Cohen-Overbeek TE, Offringa M, Barth PG, Stoutenbeek P, Gooskens RH, Wladimiroff JW, Bilardo CM. Audit of prenatal and postnatal diagnosis of isolated open spina bifida in three university hospitals in The Netherlands. Ultrasound Obstet Gynecol. 2003 Jan; 21(1):48-52. PMID: 12528161.
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    133. Henderson-Smart DJ, Bhuta T, Cools F, Offringa M. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2003; (1):CD000104. PMID: 12535383.
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    134. Groothoff JW, Gruppen MP, Offringa M, de Groot E, Stok W, Bos WJ, Davin JC, Lilien MR, Van de Kar NC, Wolff ED, Heymans HS. Increased arterial stiffness in young adults with end-stage renal disease since childhood. J Am Soc Nephrol. 2002 Dec; 13(12):2953-61. PMID: 12444214.
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    135. Groothoff JW, Grootenhuis M, Dommerholt A, Gruppen MP, Offringa M, Heymans HS. Impaired cognition and schooling in adults with end stage renal disease since childhood. Arch Dis Child. 2002 Nov; 87(5):380-5. PMID: 12390905.
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    136. Assendelft WJ, van Tulder MW, van Everdingen JJ, Offringa M, Bouter LM. [Systematic reviews in practice. IX. Determining their place in treatment recommendations in practice guidelines]. Ned Tijdschr Geneeskd. 2002 Aug 17; 146(33):1527-31. PMID: 12212498.
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    137. Kremer LC, van der Pal HJ, Offringa M, van Dalen EC, Voûte PA. Frequency and risk factors of subclinical cardiotoxicity after anthracycline therapy in children: a systematic review. Ann Oncol. 2002 Jun; 13(6):819-29. PMID: 12123328.
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    138. Kremer LC, van Dalen EC, Offringa M, Voûte PA. Frequency and risk factors of anthracycline-induced clinical heart failure in children: a systematic review. Ann Oncol. 2002 Apr; 13(4):503-12. PMID: 12056699.
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    139. Kremer LC, Bastiaansen BA, Offringa M, Lam J, van Straalen JP, de Winter RJ, Voûte PA. Troponin T in the first 24 hours after the administration of chemotherapy and the detection of myocardial damage in children. Eur J Cancer. 2002 Mar; 38(5):686-9. PMID: 11916551.
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    140. Groothoff JW, Gruppen MP, Offringa M, Hutten J, Lilien MR, Van De Kar NJ, Wolff ED, Davin JC, Heymans HS. Mortality and causes of death of end-stage renal disease in children: a Dutch cohort study. Kidney Int. 2002 Feb; 61(2):621-9. PMID: 11849405.
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    141. Coutinho HM, Groothoff JW, Offringa M, Gruppen MP, Heymans HS. De novo malignancy after paediatric renal replacement therapy. Arch Dis Child. 2001 Dec; 85(6):478-83. PMID: 11719332.
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    142. Offringa M, Moyer VA. Evidence based paediatrics: Evidence based management of seizures associated with fever. BMJ. 2001 Nov 10; 323(7321):1111-4. PMID: 11701580.
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    143. Offringa M, Moyer VA. An evidence-based approach to managing seizures associated with fever in children. West J Med. 2001 Oct; 175(4):254-9. PMID: 11577055.
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    144. Assendelft WJ, Scholten RJ, Hoving JL, Offringa M, Bouter LM. [Systematic reviews in practice. VIII. Searching and assessing systematic reviews]. Ned Tijdschr Geneeskd. 2001 Aug 25; 145(34):1625-31. PMID: 11552363.
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    145. van Karnebeek CD, Naeff MS, Mulder BJ, Hennekam RC, Offringa M. Natural history of cardiovascular manifestations in Marfan syndrome. Arch Dis Child. 2001 Feb; 84(2):129-37. PMID: 11159287.
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    146. Kremer LC, van Dalen EC, Offringa M, Ottenkamp J, Voûte PA. Anthracycline-induced clinical heart failure in a cohort of 607 children: long-term follow-up study. J Clin Oncol. 2001 Jan 01; 19(1):191-6. PMID: 11134212.
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    147. Henderson-Smart DJ, Bhuta T, Cools F, Offringa M. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2001; (3):CD000104. PMID: 11686950.
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    148. Vos JM, Offringa M, Bilardo CM, Lijmer JG, Barth PG. [Sensitive and specific screening for detection of spina bifida by echography in the second trimester; systematic review and meta-analysis]. Ned Tijdschr Geneeskd. 2000 Sep 02; 144(36):1736-41. PMID: 10992900.
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    149. Cools F, Offringa M. Neuromuscular paralysis for newborn infants receiving mechanical ventilation. Cochrane Database Syst Rev. 2000; (4):CD002773. PMID: 11034760.
      View in: PubMed
    150. Puckett RM, Offringa M. Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. Cochrane Database Syst Rev. 2000; (4):CD002776. PMID: 11034761.
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    151. de Kraker J, Bierings MB, Offringa M. Lack of protection of proximal tubular cells by amifostine (ethyol) in ifosfamide-containing regimens. Med Pediatr Oncol. 2000 Jan; 34(1):78-9. PMID: 10611598.
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    152. Henderson-Smart DJ, Bhuta T, Cools F, Offringa M. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev. 2000; (2):CD000104. PMID: 10796129.
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    153. Zondervan HA, van Gemert MJ, Nikkels PJ, Omtzigt A, Offringa M, Deprest J, Bleker OP. Twin-to-twin transfusion syndrome: a case report. Antepartum prediction of underlying placental vascular pattern in monochorionic twin pregnancies may be possible. Twin Res. 1999 Dec; 2(4):286-9. PMID: 10723807.
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    154. Kremer LC, Tiel-van Buul MM, Ubbink MC, Offringa M, Ottenkamp J, Olmos RV, Voûte PA. Indium-111-antimyosin scintigraphy in the early detection of heart damage after anthracycline therapy in children. J Clin Oncol. 1999 Apr; 17(4):1208. PMID: 10561180.
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    155. Offringa M, de Craen AJ. [The practice of systematic reviews. I. Introduction]. Ned Tijdschr Geneeskd. 1999 Mar 27; 143(13):653-6. PMID: 10321295.
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    156. Cools F, Offringa M. Meta-analysis of elective high frequency ventilation in preterm infants with respiratory distress syndrome. Arch Dis Child Fetal Neonatal Ed. 1999 Jan; 80(1):F15-20. PMID: 10325805.
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    157. Offringa M, Gemke RJ, Henny CP. [Excess mortality in critically ill patients after treatment with human albumin]. Ned Tijdschr Geneeskd. 1998 Aug 15; 142(33):1855-8. PMID: 9856165.
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    158. Offringa M. Consider validity, clinical relevance, and applicability of albumin for critically ill patients. BMJ. 1998 Aug 01; 317(7154):343. PMID: 9685288.
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    159. Offringa M. Excess mortality after human albumin administration in critically ill patients. Clinical and pathophysiological evidence suggests albumin is harmful. BMJ. 1998 Jul 25; 317(7153):223-4. PMID: 9677204.
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    160. van Esch A, Steyerberg EW, van Duijn CM, Offringa M, Derksen-Lubsen G, van Steensel-Moll HA. Prediction of febrile seizures in siblings: a practical approach. Eur J Pediatr. 1998 Apr; 157(4):340-4. PMID: 9578974.
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    161. Benbassat J, Gergawi M, Offringa M, Bearman JE, Drukker A. Variability in management of symptomless microhaematuria in schoolchildren. Postgrad Med J. 1998 Mar; 74(869):161-4. PMID: 9640442.
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    162. Benbassat J, Gergawi M, Offringa M, Drukker A. Symptomless microhaematuria in schoolchildren: causes for variable management strategies. QJM. 1996 Nov; 89(11):845-54. PMID: 8977964.
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    163. Van Esch A, Van Steensel-Moll HA, Steyerberg EW, Offringa M, Habbema JD, Derksen-Lubsen G. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun; 149(6):632-7. PMID: 7767417.
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    164. van Esch A, Steyerberg EW, Berger MY, Offringa M, Derksen-Lubsen G, Habbema JD. Family history and recurrence of febrile seizures. Arch Dis Child. 1994 May; 70(5):395-9. PMID: 8017960.
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    165. Offringa M, Bossuyt PM, Lubsen J, Ellenberg JH, Nelson KB, Knudsen FU, Annegers JF, el-Radhi AS, Habbema JD, Derksen-Lubsen G, et al. Risk factors for seizure recurrence in children with febrile seizures: a pooled analysis of individual patient data from five studies. J Pediatr. 1994 Apr; 124(4):574-84. PMID: 8151472.
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    166. Tissing WJ, van Steensel-Moll HA, Offringa M. Severity of respiratory syncytial virus infections and immunoglobulin concentrations. Arch Dis Child. 1993 Jul; 69(1):156-7. PMID: 8024304.
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    167. van Krugten RJ, Bos AP, Offringa M, Tibboel D, Molenaar JC. Postoperative care after craniofacial surgery: evaluation of routine laboratory testing. Plast Reconstr Surg. 1993 Mar; 91(3):429-32. PMID: 8438012.
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    168. Tissing WJ, van Steensel-Moll HA, Offringa M. Risk factors for mechanical ventilation in respiratory syncytial virus infection. Eur J Pediatr. 1993 Feb; 152(2):125-7. PMID: 8444219.
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    169. Offringa M, Beishuizen A, Derksen-Lubsen G, Lubsen J. Seizures and fever: can we rule out meningitis on clinical grounds alone? Clin Pediatr (Phila). 1992 Sep; 31(9):514-22. PMID: 1468167.
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    170. Offringa M, Benbassat J. The value of urinary red cell shape in the diagnosis of glomerular and post-glomerular haematuria. A meta-analysis. Postgrad Med J. 1992 Aug; 68(802):648-54. PMID: 1448406.
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    171. Offringa M, Derksen-Lubsen G, Bossuyt PM, Lubsen J. [Risk factors for the occurrence of recurrent convulsions following an initial febrile convulsion]. Ned Tijdschr Geneeskd. 1992 Mar 14; 136(11):516-21. PMID: 1552954.
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    172. Offringa M, Derksen-Lubsen G, Bossuyt PM, Lubsen J. Seizure recurrence after a first febrile seizure: a multivariate approach. Dev Med Child Neurol. 1992 Jan; 34(1):15-24. PMID: 1544510.
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    173. Verburgh ME, Bruijnzeels MA, van der Wouden JC, van Suijlekom-Smit LW, van der Velden J, Hoes AW, Offringa M. Incidence of febrile seizures in The Netherlands. Neuroepidemiology. 1992; 11(4-6):169-72. PMID: 1291879.
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    174. Offringa M, Hazebroek-Kampschreur AA, Derksen-Lubsen G. Prevalence of febrile seizures in Dutch schoolchildren. Paediatr Perinat Epidemiol. 1991 Apr; 5(2):181-8. PMID: 2052480.
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    175. Offringa M, Kroes AC, Derksen-Lubsen G. Viral infections in febrile seizures. J Pediatr. 1990 Sep; 117(3):510-1. PMID: 2391613.
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    176. van Steensel-Moll HA, Tissing WJ, Offringa M, Hazelzet JA. Mechanical ventilation and respiratory syncytial virus infection. Arch Dis Child. 1990 Mar; 65(3):332. PMID: 2334216.
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