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Ran Kafri

TitleScientist
InstitutionThe Hospital for Sick Children
DepartmentCell Biology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Biography 
    Collapse education and training
    Ben-Gurion University, Beersheba, IsraelBSc09/1999Chemistry and Biophysics
    Weizmann Institute of Science, Rehovot, IsraelMSc06/2002Chemisty
    Weizmann Institute of Science, Rehovot, IsraelPhD06/2006Molecular Genetics
    Harvard Medical School, Cambridge, MassachusettsPostdoc 07/2010Systems Biology
    Collapse awards and honors
    2005Dean’s Honor Award (Distinction), Weizmann Institute of Science
    2006Dean’s Honor Award (Distinction), Weizmann Institute of Science
    2007 - 2010Fellowship, Human Frontier Science Program Organization, HFSP
    2010 - 2012Charles A. King Trust Postdoctoral Research Fellowship, Harvard Medical School
    2016 - 2021Early Researcher Award (ERA), Ministry of Research and Innovation
    2016 - 2021Canada Research Chair – Tier II, University of Toronto
    2017EMHSeed Award, University of Toronto

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X. Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth. J Exp Med. 2020 May 04; 217(5). PMID: 32097463.
      View in: PubMed
    2. Demian WL, Persaud A, Jiang C, Coyaud É, Liu S, Kapus A, Kafri R, Raught B, Rotin D. The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1. Cell Rep. 2019 05 07; 27(6):1886-1896.e6. PMID: 31067471.
      View in: PubMed
    3. Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, Avni-Magen N, Kaufman E, Ginzberg MB, Snider D, Ray S, Brecht M, Holmes MM, Meir K, Avivi A, Shams I, Berkowitz A, Shapiro AMJ, Glaser B, Ben-Sasson S, Kafri R, Dor Y. Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals. Dev Cell. 2018 06 18; 45(6):726-737.e3. PMID: 29920277.
      View in: PubMed
    4. Ginzberg MB, Chang N, D'Souza H, Patel N, Kafri R, Kirschner MW. Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity. Elife. 2018 06 11; 7. PMID: 29889021.
      View in: PubMed
    5. Liu S, Ginzberg MB, Patel N, Hild M, Leung B, Li Z, Chen YC, Chang N, Wang Y, Tan C, Diena S, Trimble W, Wasserman L, Jenkins JL, Kirschner MW, Kafri R. Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length. Elife. 2018 03 29; 7. PMID: 29595474.
      View in: PubMed
    6. Ginzberg MB, Kafri R, Kirschner M. Cell biology. On being the right (cell) size. Science. 2015 May 15; 348(6236):1245075. PMID: 25977557.
      View in: PubMed
    7. Kafri R, Levy J, Ginzberg MB, Oh S, Lahav G, Kirschner MW. Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle. Nature. 2013 Feb 28; 494(7438):480-3. PMID: 23446419.
      View in: PubMed
    8. Karanam K, Kafri R, Loewer A, Lahav G. Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol Cell. 2012 Jul 27; 47(2):320-9. PMID: 22841003.
      View in: PubMed
    9. Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, Kafri R, Kirschner MW, Clish CB, Mootha VK. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science. 2012 May 25; 336(6084):1040-4. PMID: 22628656.
      View in: PubMed
    10. Juang YT, Peoples C, Kafri R, Kyttaris VC, Sunahori K, Kis-Toth K, Fitzgerald L, Ergin S, Finnell M, Tsokos GC. A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report. Lupus. 2011 Mar; 20(3):243-9. PMID: 21138984.
      View in: PubMed
    11. Kafri R, Markovitch O, Lancet D. Spontaneous chiral symmetry breaking in early molecular networks. Biol Direct. 2010 May 27; 5:38. PMID: 20507625.
      View in: PubMed
    12. Tzur A, Kafri R, LeBleu VS, Lahav G, Kirschner MW. Cell growth and size homeostasis in proliferating animal cells. Science. 2009 Jul 10; 325(5937):167-71. PMID: 19589995.
      View in: PubMed
    13. Kafri R, Springer M, Pilpel Y. Genetic redundancy: new tricks for old genes. Cell. 2009 Feb 06; 136(3):389-92. PMID: 19203571.
      View in: PubMed
    14. Kafri R, Dahan O, Levy J, Pilpel Y. Preferential protection of protein interaction network hubs in yeast: evolved functionality of genetic redundancy. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1243-8. PMID: 18216251.
      View in: PubMed
    15. Kafri R, Levy M, Pilpel Y. The regulatory utilization of genetic redundancy through responsive backup circuits. Proc Natl Acad Sci U S A. 2006 Aug 01; 103(31):11653-8. PMID: 16861297.
      View in: PubMed
    16. Shenhav B, Bar-Even A, Kafri R, Lancet D. Polymer GARD: computer simulation of covalent bond formation in reproducing molecular assemblies. Orig Life Evol Biosph. 2005 Apr; 35(2):111-33. PMID: 16010993.
      View in: PubMed
    17. Kafri R, Bar-Even A, Pilpel Y. Transcription control reprogramming in genetic backup circuits. Nat Genet. 2005 Mar; 37(3):295-9. PMID: 15723064.
      View in: PubMed
    18. Kafri R, Lancet D. Probability rule for chiral recognition. Chirality. 2004 Jul; 16(6):369-78. PMID: 15190582.
      View in: PubMed
    19. Rosenwald S, Kafri R, Lancet D. Test of a statistical model for molecular recognition in biological repertoires. J Theor Biol. 2002 Jun 07; 216(3):327-36. PMID: 12183121.
      View in: PubMed
    20. Segré D, Shenhav B, Kafri R, Lancet D. The molecular roots of compositional inheritance. J Theor Biol. 2001 Dec 07; 213(3):481-91. PMID: 11735293.
      View in: PubMed
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