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Last name

Julie Lefebvre

TitleSenior Scientist
InstitutionThe Hospital for Sick Children
DepartmentNeurosciences & Mental Health
Address555 University Avenue
Toronto ON M5G 1X8
ORCID ORCID Icon0000-0002-3110-860 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Pennsylvania, Philadelphia, PAPhDCell & Molecular Biology
    McGill University, Montreal, QCBScPhysiology
    Harvard University, Cambridge, MApostdoctoral fellowshipNeurobiology
    Collapse awards and honors
    2015Sloan Research Fellowship in Neuroscience, Alfred P. Sloan Foundation
    2014 - 2019Canada Research Chair, Tier 2

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ing-Esteves S, Lefebvre JL. Time-Lapse Imaging of Neuronal Arborization using Sparse Adeno-Associated Virus Labeling of Genetically Targeted Retinal Cell Populations. J Vis Exp. 2021 03 19; (169). PMID: 33818570.
      View in: PubMed
    2. Lefebvre JL. Molecular mechanisms that mediate dendrite morphogenesis. Curr Top Dev Biol. 2021; 142:233-282. PMID: 33706919.
      View in: PubMed
    3. Carriere CH, Wang WX, Sing AD, Fekete A, Jones BE, Yee Y, Ellegood J, Maganti H, Awofala L, Marocha J, Aziz A, Wang LY, Lerch JP, Lefebvre JL. The ?-Protocadherins Regulate the Survival of GABAergic Interneurons during Developmental Cell Death. J Neurosci. 2020 11 04; 40(45):8652-8668. PMID: 33060174.
      View in: PubMed
    4. Ing-Esteves S, Kostadinov D, Marocha J, Sing AD, Joseph KS, Laboulaye MA, Sanes JR, Lefebvre JL. Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. J Neurosci. 2018 03 14; 38(11):2713-2729. PMID: 29439167.
      View in: PubMed
    5. Lefebvre JL. Neuronal territory formation by the atypical cadherins and clustered protocadherins. Semin Cell Dev Biol. 2017 09; 69:111-121. PMID: 28756270.
      View in: PubMed
    6. Lefebvre JL, Sanes JR, Kay JN. Development of dendritic form and function. Annu Rev Cell Dev Biol. 2015; 31:741-77. PMID: 26422333.
      View in: PubMed
    7. Gibson DA, Tymanskyj S, Yuan RC, Leung HC, Lefebvre JL, Sanes JR, Chédotal A, Ma L. Dendrite self-avoidance requires cell-autonomous slit/robo signaling in cerebellar purkinje cells. Neuron. 2014 Mar 05; 81(5):1040-1056. PMID: 24607227.
      View in: PubMed
    8. Lefebvre JL, Kostadinov D, Chen WV, Maniatis T, Sanes JR. Protocadherins mediate dendritic self-avoidance in the mammalian nervous system. Nature. 2012 Aug 23; 488(7412):517-21. PMID: 22842903.
      View in: PubMed
    9. Chen WV, Alvarez FJ, Lefebvre JL, Friedman B, Nwakeze C, Geiman E, Smith C, Thu CA, Tapia JC, Tasic B, Sanes JR, Maniatis T. Functional significance of isoform diversification in the protocadherin gamma gene cluster. Neuron. 2012 Aug 09; 75(3):402-9. PMID: 22884324.
      View in: PubMed
    10. Jing L, Lefebvre JL, Gordon LR, Granato M. Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor. Neuron. 2009 Mar 12; 61(5):721-33. PMID: 19285469.
      View in: PubMed
    11. Lefebvre JL, Zhang Y, Meister M, Wang X, Sanes JR. gamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina. Development. 2008 Dec; 135(24):4141-51. PMID: 19029044.
      View in: PubMed
    12. Lefebvre JL, Jing L, Becaficco S, Franzini-Armstrong C, Granato M. Differential requirement for MuSK and dystroglycan in generating patterns of neuromuscular innervation. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2483-8. PMID: 17284594.
      View in: PubMed
    13. Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS. FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development. Development. 2006 Dec; 133(24):4827-38. PMID: 17092955.
      View in: PubMed
    14. Schweitzer J, Becker T, Lefebvre J, Granato M, Schachner M, Becker CG. Tenascin-C is involved in motor axon outgrowth in the trunk of developing zebrafish. Dev Dyn. 2005 Nov; 234(3):550-66. PMID: 16110513.
      View in: PubMed
    15. Zhang J, Lefebvre JL, Zhao S, Granato M. Zebrafish unplugged reveals a role for muscle-specific kinase homologs in axonal pathway choice. Nat Neurosci. 2004 Dec; 7(12):1303-9. PMID: 15543140.
      View in: PubMed
    16. Lefebvre JL, Ono F, Puglielli C, Seidner G, Franzini-Armstrong C, Brehm P, Granato M. Increased neuromuscular activity causes axonal defects and muscular degeneration. Development. 2004 Jun; 131(11):2605-18. PMID: 15128655.
      View in: PubMed
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