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Karel O'Brien

TitleAssociate Staff
InstitutionThe Hospital for Sick Children
DepartmentNeonatology
Address555 University Avenue
Toronto ON M5G 1X8
Phone416-813-1500
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Franck LS, O'Brien K. The evolution of family-centered care: From supporting parent-delivered interventions to a model of family integrated care. Birth Defects Res. 2019 May 21. PMID: 31115181.
      View in: PubMed
    2. O'Brien K, Lui K, Tarnow-Mordi W, Lee SK. Breastfeeding data in the Family Integrated Care trial. Lancet Child Adolesc Health. 2018 04; 2(4):e5. PMID: 30169303.
      View in: PubMed
    3. O'Brien K, Robson K, Bracht M, Cruz M, Lui K, Alvaro R, da Silva O, Monterrosa L, Narvey M, Ng E, Soraisham A, Ye XY, Mirea L, Tarnow-Mordi W, Lee SK. Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial. Lancet Child Adolesc Health. 2018 04; 2(4):245-254. PMID: 30169298.
      View in: PubMed
    4. Shah PS, McDonald SD, Barrett J, Synnes A, Robson K, Foster J, Pasquier JC, Joseph KS, Piedboeuf B, Lacaze-Masmonteil T, O'Brien K, Shivananda S, Chaillet N, Pechlivanoglou P. The Canadian Preterm Birth Network: a study protocol for improving outcomes for preterm infants and their families. CMAJ Open. 2018 Jan 18; 6(1):E44-E49. PMID: 29348260.
      View in: PubMed
    5. Barton M, Shen A, O'Brien K, Robinson JL, Davies HD, Simpson K, Asztalos E, Langley J, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Yau YC, Richardson SE. Early-Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome. Clin Infect Dis. 2017 Apr 01; 64(7):921-927. PMID: 28077516.
      View in: PubMed
    6. King SK, Alfaraj M, Gaiteiro R, O'Brien K, Moraes T, Humpl T, Marcon M, Chiang M, Reyes J, Haliburton B, Ryan G, Cox P, Chiu PP. Congenital diaphragmatic hernia: Observed/expected lung-to-head ratio as a predictor of long-term morbidity. J Pediatr Surg. 2016 May; 51(5):699-702. PMID: 26932249.
      View in: PubMed
    7. O'Brien K, Bracht M, Robson K, Ye XY, Mirea L, Cruz M, Ng E, Monterrosa L, Soraisham A, Alvaro R, Narvey M, Da Silva O, Lui K, Tarnow-Mordi W, Lee SK. Evaluation of the Family Integrated Care model of neonatal intensive care: a cluster randomized controlled trial in Canada and Australia. BMC Pediatr. 2015 Dec 15; 15:210. PMID: 26671340.
      View in: PubMed
    8. Gibbins S, Stevens B, Dionne K, Yamada J, Pillai Riddell R, McGrath P, Asztalos E, O'Brien K, Beyene J, McNamara P, Johnston C. Perceptions of health professionals on pain in extremely low gestational age infants. Qual Health Res. 2015 Jun; 25(6):763-74. PMID: 25854616.
      View in: PubMed
    9. Jiang S, Warre R, Qiu X, O'Brien K, Lee SK. Parents as practitioners in preterm care. Early Hum Dev. 2014 Nov; 90(11):781-5. PMID: 25246323.
      View in: PubMed
    10. Barton M, O'Brien K, Robinson JL, Davies DH, Simpson K, Asztalos E, Langley JM, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Richardson SE. Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls. BMC Infect Dis. 2014 Jun 12; 14:327. PMID: 24924877.
      View in: PubMed
    11. Doyle LW, Schmidt B, Anderson PJ, Davis PG, Moddemann D, Grunau RE, O'Brien K, Sankaran K, Herlenius E, Roberts R. Reduction in developmental coordination disorder with neonatal caffeine therapy. J Pediatr. 2014 Aug; 165(2):356-359.e2. PMID: 24840756.
      View in: PubMed
    12. Lee SK, O'Brien K. Parents as primary caregivers in the neonatal intensive care unit. CMAJ. 2014 Aug 05; 186(11):845-7. PMID: 24710910.
      View in: PubMed
    13. Coles N, Wolfe-Wylie M, Atkinson A, O'Brien K, Unger S. Case 2: Sepsis and shock in a term neonate. Paediatr Child Health. 2013 Nov; 18(9):497-8. PMID: 24426811.
      View in: PubMed
    14. Galarza-Winton ME, Dicky T, O'Leary L, Lee SK, O'Brien K. Implementing family-integrated care in the NICU: educating nurses. Adv Neonatal Care. 2013 Oct; 13(5):335-40. PMID: 24042139.
      View in: PubMed
    15. Macdonell K, Christie K, Robson K, Pytlik K, Lee SK, O'Brien K. Implementing family-integrated care in the NICU: engaging veteran parents in program design and delivery. Adv Neonatal Care. 2013 Aug; 13(4):262-9, quiz 270-1. PMID: 23912018.
      View in: PubMed
    16. Bracht M, O'Leary L, Lee SK, O'Brien K. Implementing family-integrated care in the NICU: a parent education and support program. Adv Neonatal Care. 2013 Apr; 13(2):115-26. PMID: 23532031.
      View in: PubMed
    17. O'Brien K, Bracht M, Macdonell K, McBride T, Robson K, O'Leary L, Christie K, Galarza M, Dicky T, Levin A, Lee SK. A pilot cohort analytic study of Family Integrated Care in a Canadian neonatal intensive care unit. BMC Pregnancy Childbirth. 2013; 13 Suppl 1:S12. PMID: 23445639.
      View in: PubMed
    18. Zhang Q, Macartney J, Sampaio L, O'Brien K. High Frequency Jet Ventilation during Initial Management, Stabilization, and Transport of Newborn Infants with Congenital Diaphragmatic Hernia: A Case Series. Crit Care Res Pract. 2013; 2013:937871. PMID: 23346391.
      View in: PubMed
    19. Shah V, O'Brien K. NIPPV after Surfactant Treatment for RDS Reduces the Need for Mechanical Ventilation at 7 Days of Age and BPD in Preterm Infants: Interpret Results with Caution. J Clin Neonatol. 2012 Jul; 1(3):115-7. PMID: 24027703.
      View in: PubMed
    20. Safavi A, Synnes AR, O'Brien K, Chiang M, Skarsgard ED, Chiu PP. Multi-institutional follow-up of patients with congenital diaphragmatic hernia reveals severe disability and variations in practice. J Pediatr Surg. 2012 May; 47(5):836-41. PMID: 22595557.
      View in: PubMed
    21. O'Brien K, Campbell C, Brown L, Wenger L, Shah V. Infant flow biphasic nasal continuous positive airway pressure (BP- NCPAP) vs. infant flow NCPAP for the facilitation of extubation in infants' = 1,250 grams: a randomized controlled trial. BMC Pediatr. 2012 Apr 04; 12:43. PMID: 22475409.
      View in: PubMed
    22. Frisk V, Jakobson LS, Unger S, Trachsel D, O'Brien K. Long-term neurodevelopmental outcomes of congenital diaphragmatic hernia survivors not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2011 Jul; 46(7):1309-18. PMID: 21763827.
      View in: PubMed
    23. Stevens B, Riahi S, Cardoso R, Ballantyne M, Yamada J, Beyene J, Breau L, Camfield C, Finley GA, Franck L, Gibbins S, Howlett A, McGrath PJ, McKeever P, O'Brien K, Ohlsson A. The influence of context on pain practices in the NICU: perceptions of health care professionals. Qual Health Res. 2011 Jun; 21(6):757-70. PMID: 21357756.
      View in: PubMed
    24. Alfaraj MA, Shah PS, Bohn D, Pantazi S, O'Brien K, Chiu PP, Gaiteiro R, Ryan G. Congenital diaphragmatic hernia: lung-to-head ratio and lung volume for prediction of outcome. Am J Obstet Gynecol. 2011 Jul; 205(1):43.e1-8. PMID: 21529758.
      View in: PubMed
    25. Nasef N, O'Brien K, Wylie L, Unger S. Lessons from SARS: a retrospective study of outpatient care during an infectious disease outbreak. BMC Pediatr. 2010 Jul 20; 10:51. PMID: 20646293.
      View in: PubMed
    26. Stevens B, McGrath P, Ballantyne M, Yamada J, Dupuis A, Gibbins S, Franck L, Allen Finley G, Howlett A, Johnston C, O'Brien K, Ohlsson A. Influence of risk of neurological impairment and procedure invasiveness on health professionals' management of procedural pain in neonates. Eur J Pain. 2010 Aug; 14(7):735-41. PMID: 20047845.
      View in: PubMed
    27. Unger S, Wylie L, Fallah S, Heinrich L, O'Brien K. Motivated by money? The impact of financial incentive for the research team on study recruitment. IRB. 2010 Jan-Feb; 32(1):16-9. PMID: 20184220.
      View in: PubMed
    28. Robinson JL, Davies HD, Barton M, O'Brien K, Simpson K, Asztalos E, Synnes A, Rubin E, Le Saux N, Hui C, Langley JM, Sauve R, de Repentigny L, Kovacs L, Tan B, Richardson SE. Characteristics and outcome of infants with candiduria in neonatal intensive care - a Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study. BMC Infect Dis. 2009 Nov 23; 9:183. PMID: 19930662.
      View in: PubMed
    29. Stevens B, McGrath P, Dupuis A, Gibbins S, Beyene J, Breau L, Camfield C, Finley GA, Franck LS, Howlett A, Johnston C, McKeever P, O'Brien K, Ohlsson A, Yamada J. Indicators of pain in neonates at risk for neurological impairment. J Adv Nurs. 2009 Feb; 65(2):285-96. PMID: 19040693.
      View in: PubMed
    30. Gibbins S, Stevens B, McGrath P, Dupuis A, Yamada J, Beyene J, Breau L, Camfield C, Finley GA, Franck L, Johnston C, McKeever P, O'Brien K, Ohlsson A. Changes in physiological and behavioural pain indicators over time in preterm and term infants at risk for neurologic impairment. Early Hum Dev. 2008 Nov; 84(11):731-8. PMID: 18565699.
      View in: PubMed
    31. Sampalis JS, Langley J, Carbonell-Estrany X, Paes B, O'Brien K, Allen U, Mitchell I, Aloy JF, Pedraz C, Michaliszyn AF. Development and validation of a risk scoring tool to predict respiratory syncytial virus hospitalization in premature infants born at 33 through 35 completed weeks of gestation. Med Decis Making. 2008 Jul-Aug; 28(4):471-80. PMID: 18556643.
      View in: PubMed
    32. Barton P, Bracht M, Cranis M, O'Doherty B, Dennis M, James A, O'Brien K. A patient-centric, Internet-based application for the data management of a multi-centre respiratory syncytial virus prophylaxis program. AMIA Annu Symp Proc. 2007 Oct 11; 867. PMID: 18693968.
      View in: PubMed
    33. Gibbins S, Stevens B, McGrath PJ, Yamada J, Beyene J, Breau L, Camfield C, Finley A, Franck L, Johnston C, Howlett A, McKeever P, O'Brien K, Ohlsson A. Comparison of pain responses in infants of different gestational ages. Neonatology. 2008; 93(1):10-8. PMID: 17630493.
      View in: PubMed
    34. Stevens B, Franck L, Gibbins S, McGrath PJ, Dupuis A, Yamada J, Beyene J, Camfield C, Finley GA, Johnston C, O'Brien K, Ohlsson A. Determining the structure of acute pain responses in vulnerable neonates. Can J Nurs Res. 2007 Jun; 39(2):32-47. PMID: 17679584.
      View in: PubMed
    35. Smith GN, Walker MC, Ohlsson A, O'Brien K, Windrim R. Randomized double-blind placebo-controlled trial of transdermal nitroglycerin for preterm labor. Am J Obstet Gynecol. 2007 Jan; 196(1):37.e1-8. PMID: 17240225.
      View in: PubMed
    36. Stevens B, McGrath P, Gibbins S, Beyene J, Breau L, Camfield C, Finley A, Franck L, Howlett A, Johnston C, McKeever P, O'Brien K, Ohlsson A, Yamada J. Determining behavioural and physiological responses to pain in infants at risk for neurological impairment. Pain. 2007 Jan; 127(1-2):94-102. PMID: 16997468.
      View in: PubMed
    37. Moore AM, O'Brien K. Follow-up issues with multiples. Paediatr Child Health. 2006 May; 11(5):283-6. PMID: 19030290.
      View in: PubMed
    38. Stevens B, McGrath P, Yamada J, Gibbins S, Beyene J, Breau L, Camfield C, Finley A, Franck L, Howlett A, Johnston C, McKeever P, O'Brien K, Ohlsson A. Identification of pain indicators for infants at risk for neurological impairment: a Delphi consensus study. BMC Pediatr. 2006 Feb 02; 6:1. PMID: 16457711.
      View in: PubMed
    39. Breau LM, McGrath PJ, Stevens B, Beyene J, Camfield C, Finley GA, Franck L, Gibbins S, Howlett A, McKeever P, O'Brien K, Ohlsson A. Judgments of pain in the neonatal intensive care setting: a survey of direct care staffs' perceptions of pain in infants at risk for neurological impairment. Clin J Pain. 2006 Feb; 22(2):122-9. PMID: 16428945.
      View in: PubMed
    40. Bracht M, Heffer M, O'Brien K. Development, implementation, and evaluation of a community- and hospital-based respiratory syncytial virus prophylaxis program. Adv Neonatal Care. 2005 Feb; 5(1):39-49. PMID: 15685161.
      View in: PubMed
    41. Bracht M, Heffer M, O'Brien K. Family teaching toolbox. Preventing respiratory syncytial virus (RSV) infection. Adv Neonatal Care. 2005 Feb; 5(1):50-1. PMID: 15685162.
      View in: PubMed
    42. Breau LM, McGrath PJ, Stevens B, Beyene J, Camfield CS, Finley GA, Franck L, Howlett A, O'Brien K, Ohlsson A. Healthcare professionals' perceptions of pain in infants at risk for neurological impairment. BMC Pediatr. 2004 Nov 12; 4(1):23. PMID: 15541179.
      View in: PubMed
    43. Law BJ, Langley JM, Allen U, Paes B, Lee DS, Mitchell I, Sampalis J, Walti H, Robinson J, O'Brien K, Majaesic C, Caouette G, Frenette L, Le Saux N, Simmons B, Moisiuk S, Sankaran K, Ojah C, Singh AJ, Lebel MH, Bacheyie GS, Onyett H, Michaliszyn A, Manzi P, Parison D. The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation. Pediatr Infect Dis J. 2004 Sep; 23(9):806-14. PMID: 15361717.
      View in: PubMed
    44. Stevens B, McGrath P, Gibbins S, Beyene J, Breau L, Camfield C, Finley A, Franck L, Howlett A, McKeever P, O'Brien K, Ohlsson A, Yamada J. Procedural pain in newborns at risk for neurologic impairment. Pain. 2003 Sep; 105(1-2):27-35. PMID: 14499417.
      View in: PubMed
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