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IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

Morini E, Prudente S, Succurro E, Chandalia M, Zhang YY, Mammarella S, Pellegrini F, Powers C, Proto V, Dallapiccola B, Cama A, Sesti G, Abate N, Doria A, Trischitta V. IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants. Diabetologia. 2009 Sep; 52(9):1852-7.

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