 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1986 | 0 | 1 | 1 | | 1989 | 2 | 0 | 2 | | 1990 | 1 | 1 | 2 | | 1991 | 1 | 2 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 2 | 3 | | 1994 | 1 | 0 | 1 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 2 | 3 | | 1998 | 1 | 3 | 4 | | 1999 | 2 | 2 | 4 | | 2000 | 3 | 6 | 9 | | 2001 | 1 | 2 | 3 | | 2002 | 4 | 7 | 11 | | 2003 | 1 | 2 | 3 | | 2004 | 1 | 6 | 7 | | 2005 | 2 | 4 | 6 | | 2006 | 2 | 2 | 4 | | 2007 | 1 | 4 | 5 | | 2008 | 0 | 5 | 5 | | 2009 | 1 | 3 | 4 | | 2010 | 2 | 7 | 9 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 7 | 9 | | 2014 | 1 | 6 | 7 | | 2015 | 2 | 2 | 4 | | 2016 | 1 | 4 | 5 | | 2017 | 1 | 2 | 3 | | 2018 | 2 | 2 | 4 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Freeman SA, Grinstein S. Phagocytosis: Mechanosensing, Traction Forces, and a Molecular Clutch. Curr Biol. 2020 01 06; 30(1):R24-R26.
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Ostrowski PP, Freeman SA, Fairn G, Grinstein S. Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides. Dev Cell. 2019 08 19; 50(4):397-410.e3.
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Coquenlorge S, Yin WC, Yung T, Pan J, Zhang X, Mo R, Belik J, Hui CC, Kim TH. GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis. Cell Rep. 2019 06 04; 27(10):3006-3018.e4.
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Boddy KC, Gao AD, Truong D, Kim MS, Froese CD, Trimble WS, Brumell JH. Septin-regulated actin dynamics promote Salmonella invasion of host cells. Cell Microbiol. 2018 10; 20(10):e12866.
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Vega AR, Freeman SA, Grinstein S, Jaqaman K. Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis. Biophys J. 2018 03 13; 114(5):1018-1025.
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Niedergang F, Grinstein S. How to build a phagosome: new concepts for an old process. Curr Opin Cell Biol. 2018 02; 50:57-63.
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Schlam D, Grinstein S, Freeman SA. Screening for Rho GTPase Modulators in Actin-Dependent Processes Exemplified by Phagocytosis. Methods Mol Biol. 2018; 1821:107-127.
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Chen J, Zhong MC, Guo H, Davidson D, Mishel S, Lu Y, Rhee I, Pérez-Quintero LA, Zhang S, Cruz-Munoz ME, Wu N, Vinh DC, Sinha M, Calderon V, Lowell CA, Danska JS, Veillette A. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. 2017 04 27; 544(7651):493-497.
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Kahr WH, Pluthero FG, Elkadri A, Warner N, Drobac M, Chen CH, Lo RW, Li L, Li R, Li Q, Thoeni C, Pan J, Leung G, Lara-Corrales I, Murchie R, Cutz E, Laxer RM, Upton J, Roifman CM, Yeung RS, Brumell JH, Muise AM. Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. Nat Commun. 2017 04 03; 8:14816.
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Wang JC, Lee JY, Christian S, Dang-Lawson M, Pritchard C, Freeman SA, Gold MR. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017 03 15; 130(6):1094-1109.
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