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Adaptor Proteins, Signal TransducingConcept Why?
Brumell, JohnPerson Why?
McGlade, CatherinePerson Why?
Grinstein, SergioPerson Why?
A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.Academic Article Why?
A double hit implicates DIAPH3 as an autism risk gene.Academic Article Why?
A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.Academic Article Why?
A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.Academic Article Why?
A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.Academic Article Why?
Absent CNKSR2 causes seizures and intellectual, attention, and language deficits.Academic Article Why?
Adult-onset autosomal dominant centronuclear myopathy due to BIN1 mutations.Academic Article Why?
APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction.Academic Article Why?
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.Academic Article Why?
Autoantibodies to Dense Fine Speckles in Pediatric Diseases and Controls.Academic Article Why?
Caspase-dependent cleavage of the hematopoietic specific adaptor protein Gads alters signalling from the T cell receptor.Academic Article Why?
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